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TVWS Multi-channel Cluster Tree PAN 성능평가
장인 ( In Jang ),황광일 ( Kwang-il Hwang ),최석준 ( Seok-jun Choi ),심병섭 ( Byoung-sup Sim ) 한국정보처리학회 2013 한국정보처리학회 학술대회논문집 Vol.20 No.2
본 논문에서는 무선 주파수 자원의 부족문제가 대두됨에 따라 TV White Space(TVWS) 주파수 대역을 효과적으로 사용하기 위한 IEEE 802.15.4m TVWS Multi-channel Cluster PAN(TMCTP)을 소개하고 NS-3 를 이용하여 Association 시간과 Uplink, Downlink 데이터 전송시간에 대한 성능평가를 한다. 성능평가 결과에 대하여 분석하고 향후 TMCTP 의 추가할 부분에 대하여 도출한다.
Acetaminophen 유도 마우스 간 손상에 대한 가감공진단(加減拱辰丹) 추출물의 간보호 효과
장선일 ( Seon Il Jang ),김홍준 ( Hong Hun Kim ),목지예 ( Ji Ye Mok ),박광현 ( Kwang Hyun Park ),정승일 ( Seung Il Jeong ),황병순 ( Byung Soon Hwang ),황성연 ( Sung Yeoun Hwang ),조정근 ( Jung Keun Cho ) 대한본초학회 2010 大韓本草學會誌 Vol.25 No.3
Objective: Gagam-Gongjin-dan (GGD) is an oriental medicinal prescription composited with Cervi parvum Cornu, Corni Fructus, Angelica Gigantis Radix, Lycii Fructus, Dioscoreae Rhizoma, Citri Pericarpium, Gastrodiae Rihzoma, Agastachis Herba, Cassiae cortex, Scutellariae Radix and Schisandrae Fructus. The purpose of this study was to investigate the effects of GGD extract against acetaminophen (APAP)-induced liver injury in mice. Methods: GGD extract was prepared by extracting with methanol for 7 days. The extract was freeze-dried following filtration through vacuum distillation system. The first, we investigated the antioxidant effects of GGD extract on electronic donating ability (DPPH), nitrite (NO) scavenging and superoxide dismutase (SOD)-like activity. The next, we investigated the possible hepatoprotective effect of GGD extract administration against acetaminophen-induced liver injury in mice. Mice were orally administrated with or without GGD extract of different doses (25-100mg/kg/day) one times per day for 6 days. After 3 days, APAP was orally applied with a single dose (400mg/kg). Results:GGD extract increased DPPH, NO and SOD-like activities in dose dependant. APAP treatment significantly increased aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities in plasma. Also, APAP treatment significantly evaluated lipid peroxidation product thiobarbituric reacting substances (TBARS) and depleted some antioxidant enzymes (superoxide dismutase, catalase, d-aminolevulinate dehydratase and gluthathione peroxidase activities) in liver homogenates compared to the control group. However, the orally administration of GGD extract was able to counteract these effects. Histological studies provided supportive evidence for biochemical analysis Conclusions: These results suggest that GGD extract has a potential antioxidant and hepatoprotective effect against APAP-induced liver injury, these properties may contribute to liver disease care.
Acetaminophen 유도 간 손상에 대한 조릿대 애엽 추출물의 보호 효과
장선일,윤용갑,박광현,설광화,권태오,Jang, Seon-Il,Yun, Young-Gab,Park, Kwang-Hyun,Xie, Guanghua,Kwon, Tae-Oh 대한한의학방제학회 2008 大韓韓醫學方劑學會誌 Vol.16 No.2
Acetaminophen (N-acety1-p-aminophenol, paracetamol) is widely used as an over-the-counter analgesic and antipyretic drug. Intake of a over dose of acetaminophen may result in severe hepatic necrosis. In this study, we investigated the liver damage in mice using single dose (300 mg/kg) of acetaminophen and the possible protective effects of administration (50-200 mg/kg body weight) of SB-Ex on acetaminophen-induced liver damage in mice. The alanine aminotransferase (ALT), and aspartate aminotransferase (AST) activities were determined in the plasma of mice. The effect of SB-Ex on lipid peroxidation product thiobarbituric reacting substances (TBARS) and some antioxidant enzymes superoxide dismutase (SOD), catalase, d-aminolevulinate dehydratase (${\sigma}$-ALA-D) activities, and gluthathione peroxidase (GPx), were also evaluated in the mouse liver homogenate. Acetaminophen caused liver damage as evident by statistically significant increased in plasma activities of AST and ALT. There were general statistically significant losses in the activities of SOD, catalase, ${\sigma}$-ALA-D, and GPx and an increase in TBARS in the liver of acetaminophen-treated group compared with the control group. However, SB-Ex was able to counteract these effects. These results suggest that SB-Ex can act as hepatoprotectives against acetaminophen toxicity and is a good candidate for further evaluation as an effective chemotherapeutic agent.
에틸렌 흡착제와 활성탄 처리에 의한 저장 포도의 품질 특성
장금일(Keum-Il Jang),이제홍(Je-Hong Lee),김광엽(Kwang-Yup Kim),정헌상(Heon-Sang Jeong),이희봉(Hee-Bong Lee) 한국식품영양과학회 2006 한국식품영양과학회지 Vol.35 No.9
포도의 저장성을 향상시킬 수 있는 방법을 모색하기 위하여 ‘Sheridan’과 ‘Muscat Bailey A’ 품종을 에틸렌 흡착제 및 0.1, 0.5, 1.0 및 2.0%의 활성탄을 처리하여 0±1℃에서 90±2%의 습도상태에서 60일간 저장하면서 중량감모율, 비정상과 발생률, 탈립율, 당도, 유리당함량, 총산, anthocyanin 색소 함량, 진균수를 조사하였다. 전체적으로 ‘Sheridan’, ‘Muscat Bailey A’ 두 품종 모두 무처리에 비하여 에틸렌 흡착제 및 활성탄을 처리하였을 때 저장성이 증가하였다. 품종별로는 ‘Sheridan’이 ‘Muscat Bailey A’보다 저장성이 우수하였으며, 처리구별로 무처리구에 비하여 에틸렌 흡착제, 활성탄 수준이 높을수록 중량감모율, 비정상과 발생률, 탈립율, 당도 및 진균수의 증가에 대한 억제 효율이 높게 나타났다. 그리고 유리당 함량 및 포도과피의 anthocyianin 함량을 조사한 결과 ‘Sheridan’, ‘Muscat Bailey A’ 두 품종 모두 저장 기간 중 유리당 함량 및 포도 과피의 anthocyanin 함량이 조금 증가하였고, 품종별로는 ‘Sheridan’이 ‘Muscat Bailey A’보다 증가율이 높게 나타났지만, 처리구간 유의적인 차이는 적었다, 또한, 총산은 ‘Sheridan’과 ‘Muscat Bailey A’ 두 품종 모두 저장 기간 중 감소하는 경향을 나타낸 반면, 처리구별 차이는 적었고 품종별로는 ‘Sheridan’이 ‘Muscat Bailey A’보다 적게 감소하였다. 전체적인 결과를 종합해보면 포도 저장 중 활성탄 처리 효과가 에틸렌 흡착제에 의한 효과와 유사하게 저장성을 향상시키는 결과를 나타내었으며, 처리구별로는 에틸렌 흡착제, 2% 활성탄>1% 활성탄>0.5% 활성탄 처리 순으로 저장성이 우수하게 나타났다. In order to ensure a stable supply of grapes for consumers and to extend grape storage, we investigated changes in the quality of grapes (Vitis labruscana) stored after treatment with ethylene-absorbent (EA) or activated charcoal (AC). We treated harvested ‘Sheridan’ and ‘Muscat Bailey A’ grapes with EA and with 0.1, 0.5, 1.0, and 2.0% (w/w) AC, and stored them at 0±1℃, 90±2% humidity for 60 days. After the EA or AC treatment, the storability of the ‘Sheridan’ and ‘Muscat Bailey A’ grapes was increased, as compared with non-treatment, and ‘Sheridan’ kept better than ‘Muscat Bailey A’. The quality of the stored grapes maintained with EA or the amount of AC, which decreased the rate of weight loss, abnormal fruit development, berry abscission, saccharinity, and growth of fungi. The free sugar and anthocyanin contents in the pericarp increased gradually in both ‘Sheridan’ and ‘Muscat Bailey A’, and increased more in ‘Sheridan’. Conversely, the total acidity of ‘Sheridan’ and ‘Muscat Bailey A’ decreased with storage, and decreased less in ‘Sheridan’. There were no differences in the free sugar content, anthocyanin content, and total acidity among treatments. The changes in grape quality with storage were delayed in the order of EA, 2% AC, 1% AC, 0.5% AC, and 0.1% AC. Ultimately, we postulate that EA and 2% AC best maintain the qualities of grape, and extend the grape storage period.
균형 경사형 신발이 임산부의 보행과 족저압에 미치는 효과
장석일 ( Suck Il Jang ),이유리 ( Yu Ri Lee ),곽형심 ( Hyung Sim Kwak ),문광섭 ( Kwang Sup Moon ),신종철 ( Jong Chul Shin ),김장흡 ( Jang Heub Kim ) 대한산부인과학회 2010 Obstetrics & Gynecology Science Vol.53 No.11
목적: 본 연구는 균형 경사형 신발이 임산부의 안정된 보행, 피로 감소, 혈액순환 개선, 그리고 발 관련 질병에 미치는 효과를 조사하였다. 연구 방법: 병력이 없는 임신 7~9개월의 임산부 7명과 출산 후 3개월 이내의 산모 3명을 대상으로 각각 평면형 신발과 균형 경사형 신발을 착용하고 보행 실험을 실시하였다. 3차원 동작분석, 족저압력측정, 그리고 혈류속도에 대한 두 가지 보행 조건하의 실험이 통계적으로 조사되었고, 일원분산분석 방식의 통계방법을 사용하였다. 결과: 10명의 피험자 중 오류 데이터를 제외한 9명에 대하여 보행 시 균형 경사형 신발이 평면형 신발에 비해 평균 6 mm 정도 무릎을 안쪽으로 모아주어 신발에 따른 무릎 사이 거리의 변화 특성에 유의한 차이가 있었다(P < 0.05). 균형 경사형 신발이 평면형 신발에 비해 전체적인 압력의 크기를 15% 정도 감소시켜 주고, 발꿈치에 집중되었던 압력이 발바닥 홈 외측 부위로 분산되어 압력 분포 특성에서도 유의한 차이가 있었다(P < 0.05). 혈류속도는 9명의 피험자 전체가 착화 전에는 C (200~400 μm/sec)나 D (100~200 μm/sec) 구간에 속하였지만 균형 경사형 신발을 착용한 후에는 A (> 600 μm/sec)와 B (400~600 μm/sec)구간으로 1~2구간 개선되는 경향이 있었다. 결론: 균형 경사형 신발은 자세를 바르게 하고, 보행자세를 안정화시키고, 과도한 발목의 부하를 줄이고, 피로를 감소시키며, 혈액순환을 개선하는 효과를 나타내었다. Objective: This study investigated the effects of the balanced incline shoes on the stabilized walking, fatigue reduction, improvement of blood circulation and prevention of foot related disease for the pregnant women. Methods: The seven 7~9 month pregnant women and three maternities within 3 months after delivery without a history of disease performed the cycles for each of the two walking conditions: wearing balanced incline shoes and flat shoes. The differences between the two walking conditions were statistically investigated including three dimensional motion analysis, footprint pressures and blood flow. To find out any possible difference between these two kinds and among the subjects, the statistical tool was utilized with one-way layout design. Results: Of 10 subjects, seven subjects showed the significantly decreased in distance of both knee with balanced incline shoes than flat shoes (P<0.05). Those with the balanced incline shoes had a walking pattern whose knee moved inward about 6 mm, compared to those with the flat regular ones. Over plantar pressure measurements for all ten, it also revealed statistically significant differences that the balanced incline shoes decreased its pressure 15% and that the pressure heavily on heel area was distributed outward along the arch (P<0.05). The blood stream velocity belonged to C (200~300 μm/sec) or D (100~200 μm/sec) for the nine before wearing the balanced incline shoes. However, it was found to be enhanced in A (>600 μm/sec) or B (400~600 μm/sec) after they put them on, indicating 1~2 part equivalent improvement. The blood stream velocity showed a incremental tendency after wearing balanced incline shoes. Conclusion: This result suggests that the balanced incline shoes corrected the postures, stabilized the gait pattern, decreased the excessive load on ankle plantar flexors, reduced the fatigue level and improved the blood circulation.