성인 두부백선의 임상 및 진균학적 분석(61증례, 1990∼2018)

정인순 ( In Soon Jung ),류건욱 ( Geon Wook Ryu ),윤숙정 ( Sook Jung Yun ),이지범 ( Jee Bum Lee ),김성진 ( Seong Jin Kim ),이승철 ( Seung Chul Lee ),원영호 ( Young Ho Won ) 대한피부과학회 2020 大韓皮膚科學會誌 Vol.58 No.1

Background: Tinea capitis, a superficial dermatomycosis, is caused by a dermatophyte infection on the scalp and hair. Recently, the number of adult patients with tinea capitis have been increasing; therefore, the clinical and mycological features of tinea capitis may be different from those of previous reports. However, only a few studies on adult tinea capitis have been conducted in Korea. Objective: This study aimed to analyze the clinical and mycological features of Korean adult patients with tinea capitis. Methods: A retrospective review of 61 adult patients with tinea capitis was conducted. Clinical features including age, sex, clinical type, and treatment outcome were obtained from medical records and images. The mycological features, including the result of KOH smear and fungal culture, were also analyzed. Results: The mean onset age was 61.3 years, and the male-to-female ratio was 1:4.1. Two patients (3.3%) had a family history of developing the same symptoms, and 17 (27.9%) had a history of close contact with animals. The most predilection site was the vertex, followed by the frontal and parietal areas. Microsporum canis was cultured in 66.7% patients, and Trichophyton rubrum was cultured in 28.6% patients. The number of adult patients with tinea capitis has been increasing constantly. The proportion of patients infected by T. rubrum has been increasing since 2000. Of the 51 patients who received treatments, 42 showed improvements. No significant difference was observed between patients treated with terbinafine and itraconazole. Conclusion: This is the large-scale study that analyzed the clinical and mycological features of Korean adult patients with tinea capitis. (Korean J Dermatol 2020;58(1):1∼6)

개인안전용 외피형 에어백의 개념설계 및 충격해석

정인덕(I. D. Jung),이용문(Y. M. Lee),신종국(J. G. Shin),이태구(T. G. Lee),신보성(B. S. Shin),강명창(M. C. kang) 한국기계가공학회 2016 한국기계가공학회 춘추계학술대회 논문집 Vol.2016 No.10

그래핀 물질 기반의 음향 발생장치 개발 및 산화그래핀 함침을 통한 폴리우레탄의 흡음 성능 향상

정인화(Inhwa Jung),이재혁(Jae Hyuk Lee),이형래(Hyeong Rae Lee),김재형(Jae Hyung Kim),신유진(Yu Jin Shin),강연준(Yeon June Kang) 한국소음진동공학회 2019 한국소음진동공학회 학술대회논문집 Vol.2019 No.2

분화 유도된 근육줄기세포의 내막증식 억제 효과

정인목(In Mok Jung),한소리(So Rhee Han),최금희(Keum Hee Choi),권유진(Yujin Kwon),이태승(Taeseung Lee),민승기(Seung-Kee Min),박양진(Yang Jin Park),정중기(Jung Kee Chung),하종원(Jongwon Ha),김상준(Sang Joon Kim) 대한외과학회 2010 Annals of Surgical Treatment and Research(ASRT) Vol.79 No.6

Purpose: Although progenitor cells may contribute to intimal hyperplasia (IH) after arterial injury, positive contribution of IH is variable with type of injury or cells. This study was designed to examine whether differentiated muscle derived stem cells (MDSC) attenuate IH in rat. Methods: MDSCs were retrieved using preplate techniques from rat calf muscle and MDSCs (preplate 6th culture fraction, pp6) were exposed to VEGF (50 ng/㎖) for endothelial differentiation prior to injection. Male rats were divided into two groups (cell treated vs. control) and underwent carotid balloon injury with 2-Fr catheter. The virus containing Green fluorescent protein (GFP) gene was transfected into cells for monitoring. Cells (5×10?) were indwelled into carotid artery for 30 minutes after injury and then blood flow was restored. Arteries were harvested at various intervals (1, 2 and 4 weeks) after injury. The intima to media thickness ratio (IMTR) was calculated with morphometric analysis. Results: Endothelial surface markers such as VE-CADHERIN were strongly expressed on differentiated MDSCs. At 4 weeks after injury, IH was predominantly observed in control group compared to cell treated group. The intensity of GFP was strongly observed at 1 week and declined at 4 weeks in carotid artery wall at MDSC group. CD31(+) endothelial cells were observed at MDSC group compared to control. The mean IMTR in cell treated groups were significantly lower than control at 2 weeks (P=0.005) and 4 weeks (P≤0.001). Conclusion: Our study demonstrates that MDSCs therapy promotes re-endothelialization and leads to attenuation of IH after balloon injury in rat.

급성전신발진농포증 환자의 임상 및 조직학적 분석

정인순 ( In Soon Jung ),윤숙정 ( Sook Jung Yun ),이지범 ( Jee-bum Lee ),김성진 ( Seong-jin Kim ),이승철 ( Seung-chul Lee ),원영호 ( Young Ho Won ) 대한피부과학회 2018 대한피부과학회지 Vol.56 No.10

Background: Acute generalized exanthematous pustulosis (AGEP) is typically a medication-induced acute febrile eruption. Few large-scale studies have reported clinical data regarding AGEP in Korea. Objective: This study analyzed the clinical and histopathological features of AGEP in Koreans to identify recent trends in this context. Methods: This study retrospectively reviewed 31 patients with AGEP. Age, sex, clinical features, etiologies, laboratory findings, histopathological features, and treatment outcomes were obtained from patients’ medical records and photographs. Results: The mean age of onset was 43.6 years, and the male:female ratio was 2.1:1. All patients showed non-follicular tiny pustules and erythema. Fever was reported in 13 patients and neutrophilia in 17 patients. Medications were considered the most common etiological contributors. Twenty patients showed drug-induced AGEP, and 11 of 20 patients showed antibiotic-induced AGEP. Serum C-reactive protein and lactate dehydrogenase levels increased in 93.8% and 77.8% of the patients, respectively. Histopathologically, all patients showed subcorneal or intraepidermal pustules, followed by exocytosis and neutrophilic dermal infiltrate. Twenty-five patients improved within a mean period of 7.5 days after the onset of the skin rash. The percentage of women in the drug-induced AGEP group was significantly higher than that in the non-drug-induced AGEP group. Conclusion: This report describes a large-scale study that analyzed the clinical and histopathological features of AGEP in Koreans and seems to accurately reflect the recent trends in this context. Clinically, it is important to note that the percentage of women in the drug-induced AGEP group was higher than that in groups showing other etiologies of AGEP. (Korean J Dermatol 2018;56(10):594∼602)

전치태반의 임상적 고찰

정인석 ( In Suk Jung ),오희연 ( Hee Yeon Oh ),이수 ( Soo Lee ),이재준 ( Jae Jun Lee ),성문수 ( Moon Su Sung ),김현찬 ( Hyun Chan Kim ) 대한주산의학회 1996 Perinatology Vol.7 No.3

흉부 X-Ray 검사실에서 Auto Voice Device의 유용성과 방사선사의 편의성에 관한 고찰

정인아(In-A Jung),이동희(Dong-Hee Lee),이민우(Min-Woo Lee),김순배(Sun-Bae Kim) 대한영상의학기술학회 2012 대한영상의학기술학회 논문지 Vol.2012 No.-

목적: 음성안내가 많은 흉부 X-ray 검사실에서 사용할 Auto voice device를 제작하여 장비의 유용성과 이에 따른 방사선사의 업무 편의성에 대해 알아보고자 하였다. 대상 및 방법: 2012년 01월 09일 부터 02월 24일에 걸쳐 방사선사 87명에게 검사방법과 장비사용법이 담긴 동영상을 보여준 후 연구목적과 취지를 설명하고 협조를 요청하여 설문 지를 배부하여 분석하였다. 방사선사의 일반적 특성은 성별은 남성이 58명(67.7%)으로 9 명(33.3%)인 여성의 약 2배이고, 평균연령은 36(35.89±7.90)세이며, 근무기간은 13(13.41±7.54)년, 검사건수는 300~399건이 41명(28.7%)으로 가장 많은 비중을 차지했 다. 조사결과 분석은 방사선사의 검사에 대한 일반적 견해와 개선사항과 장비의 질에 대한 견해를 파악하기 위해 빈도와 백분율을 산출하고, 검사장비도입의 효과 및 효능의 통계적 처리는 SPSS를 이용하여 일원배치 분산분석(ANOVA)을 하였다. 결과: 설문조사 결과 연령과 근무기간에 따른 Auto voice device의 유용성은 유의확률이 0.05 이상으로 모두 통계적으로 유의하지 않아 상관관계가 적은 것으로 나타났다. 그러나 검사건수에 따른 검사자의 피로도 감소는 유의확률 0.000 (p<0.01)으로 매우 유의한 결과를 얻었고, 검사건수에 따른 업무의 편의성도 유의확률 0.001 (p<0.01)으로 매우 유의하다는 결과가 나왔다. 결론: Auto voice device를 사용함으로써 업무의 편의성 증가와 목의 피로도 감소는 매우 높은 평가를 얻었다. 하지만 장비를 조작하는 시간이 추가됨에 따라서 전체적인 검사시간은 단축되지 않았고, 호흡조절도 장비를 사용하는 것과 육성을 사용하는 것을 비교하였을 때크게 다르지 않았다. 향후 개선사항들을 토대로 장비의 음질 개선과 언어의 다양화, 자막기 능을 추가하여 현재 장비의 업그레이드를 진행 중이며, 더 발전된 Auto voice device로 방사선사의 업무에 보다 더 효율을 줄 것으로 기대한다. Purpose: This study investigated usefulness of the device and its work convenience for radiologic technologist by making auto voice device used at chest X-ray lab where many voice guidance is made. Materials and Methods: The subjects are 87 radiologic technologists and they were asked to see video clip where how to use the device and method of applying to examination was introduced during the period from Jan. 9, 2012 to Feb. 24, 2012. Since then, study purpose was explained to ask for cooperation. For general characteristics of the subjects, the gender is 58 males (67.7%); 29 females (33.3%) - male is double female. Average age is 36 (35.89±7.90). Working period is 13 (13.41±7.54) years. As for number of examination by radiologic technologist, 41 radiologic technologists (28.7%) did 300-399 cases each person. To show general opinion of the subjects about examination, and opinion about improvements and quality of device, percentage was used. Effect and efficiency of using Auto voice device was analyzed using ANOVA through statistical processing by SPSS. Results: For reduction of fatigue in radiologic technologist s throat according to number of examination, p-value 0.000 (p<0.01) - this is very significant result. For work convenience according to number of examination, p-value 0.000 (p<0.01) -this is also very significant result. Conclusion: Using auto voice device brought increase of work convenience and reduction of fatigue in throat. But whole time for examination was not saved because maneuvering device requires additional time. In controlling breathing, there is no much difference between using device and human voice. It is expected that if auto voice device is improved in sound quality, variety in provided language etc. through this study results, this device would be more useful for work of radiologic technologists in the future.

성인 피부근염 환자 52명의 임상적 분석

정인순 ( In Soon Jung ),윤숙정 ( Sook Jung Yun ),이지범 ( Jee Bum Lee ),김성진 ( Seong Jin Kim ),이승철 ( Seung Chul Lee ),원영호 ( Young Ho Won ) 대한피부과학회 2018 대한피부과학회지 Vol.56 No.1

Background: Dermatomyositis is one of the idiopathic inflammatory myopathies, characterized by unique cutaneous features. Unfortunately, there is little data regarding the clinical features of dermatomyositis in Korea patients. Objective: The study aimed to analyze the clinical features of Korean patients with adult-onset dermatomyositis. Methods: A total of 52 patients from 2002 to 2016 were analyzed retrospectively. Clinical features such as sex, age, symptoms, associated connective tissue disorders and malignancy were studied using medical records. Results: The mean onset age was 43.4 years, and the male to female ratio was 1 : 1.9. Forty-two patients (80.8%) were classified as having dermatomyositis, and 8 patients (15.4%), as having amyopathic dermatomyositis. Skin rash (94.2%) was the most common clinical feature, followed by proximal muscle weakness (61.5%), itching (55.8%), arthralgia (36.5%), and muscle pain (32.7%). Among skin rashes, symmetric violaceous erythema (67.3%) was the most frequent, followed by heliotrope rash (63.5%) and Gottron’s papule (59.6%). Serum aldolase level was elevated in 77.8%, and LDH in 69.6%. The prevalence of malignancy (23.1%) was similar to that in previous studies. Cervical cancer made up 25% (3/12) of the associated malignancies, followed by ovarian cancer and lung cancer (16.7%). Ten patients (19.2%) had other accompanying connective tissue diseases. Conclusion: To date, this is the first large-scale case study that analyzed the clinical features of Korean patients with adult-onset dermatomyositis. (Korean J Dermatol 2018;56(1):24∼29)

개방 권선형 영구자석 동기전동기의 영상분 전압 저감을 위한 제어 기법

정인석(Insuk Jung),백현준(Hyunjun Baek),이창주(Changju Lee),이근호(Geunho Lee) 한국자동차공학회 2021 한국자동차공학회 학술대회 및 전시회 Vol.2021 No.11

보충수를 고려한 간척호의 담수화 분석 연구

정인균 ( Inkyun Jung ),황동주 ( Dongju Hwang ),이창희 ( Changhee Lee ),정광욱 ( Kwangwook Jung ) 한국농공학회 2012 한국농공학회 학술대회초록집 Vol.2012 No.-

시화지구에 위치한 탄도호는 호수면적에 비해 유역면적이 작아 유역자체에서 발생된 유출량은 탄도호 담수화에 충분하지 않은 상황으로 인근에 위치한 화성호의 용수를 제염보충수로 공급하는 방안을 검토하기 위하여 본 연구를 수행하였다. 국내에서 간척호의 담수화 해석에는 Jensen, Okuda, Minami 식을 주로 이용해왔으며, 현재는 DESAL(Desalinization of Salt Balance Model)을 이용하여 담수화 기간을 예측하고 있다. DESAL 모형은 농업진흥공사 시절인 1989년 일본의 Minami 식을 채택하여 개발된 국내유일의 제염해석 모형이다. Minami 식은 담수호를 담수층과 염수층의 2층류로 구분하고 층간 수직방향의 염분확산을 고려한 염분평형방정식에 의해 담수화 과정을 해석하는 방법으로서 다른 제염공식에 비해 제염과 관련된 기상조건, 제염시설, 용수취수, 용탈 등 여러 조건들을 반영할 수 있는 가장 물리적인 방법이라고 할 수 있다. 본 연구에서도 DESAL모형을 이용하였으며, 간척호인 화성호의 용수를 제염보충수로 공급하는바 보충수의 염분농도가 연계되어야 하므로 본 연구의 분석에 적합하도록 DESAL 모형을 수정하였다. 수정된 모형을 이용하여 호소간 연계모의를 통해 연중 공급시기, 보충수공급량, 1일 공급시간의 시나리오를 검토하였으며 제염보충수의 적정공급방안을 제안하였다.