부모의 물리치료 참여 및 만족도가 뇌성마비 아동의 운동기능 호전에 미치는 영향

이소영,김용남,강정일,Lee, So-Young,Kim, Yong-Nam,Kang, Jeong-Il 대한물리치료학회 2005 대한물리치료학회지 Vol.17 No.4

Family and parents which serve as a primary group for the children's development also play important role in their cerebral palsy children's treatment. This study wants to know how the parents' participation in their children's physical therapy and satisfaction degree have an impact on their children's improvement of the motor function. For that purpose, a home made self filling survey was conducted of 156 cerebral palsy children's parents whose children were treated in 4 university general hospitals and 3 welfare centers from the 1st of April 2004 to the 31th of march 2005. The gross motor function was employed to evaluate the cerebral palsy children's motor function improvement. In this study, those questioned were divided into two groups according to the time of treatment. 'Group A' is consist of the patients whose parents attended to the treatment more than one hour at home. The patients who belonged to 'Group B' were treated less than one hour at home. The general features of the cerebral palsy children and their parents and the characteristics of their physical disability, the parents' participation and their satisfaction degree were examined by survey. Evaluating the difference between two groups' motor function according to their parents participation degree in the physical therapy leads to the following results. First, 'Group A' was better than 'Group B' in their satisfaction degree with the physical therapy and participation degree. Statistically 'Group A' was superior to 'Group B' in the requirements of the information and education for the children with cerebral palsy. Second, after two months of treatment, 'Group A' showed more statistically significant improvement than 'Group B' in every items as like lying in item 1, sitting in item2, crawling and kneeling in item 3, standing in item 4, walking,running, jumping in item 5. Third, parents' participation in physical therapy and satisfaction degree have some relevance to their children' motor function improvement. The satisfaction degree is related to motor function like crawling and kneeling in item 3, walking,running, jumping in item 5. It is showed that the parents' participation degree and information about handicapped children.

담화분석을 통해 재조명하는 그라이스(Grice)의 협력 원칙 - 이기적 자아의 이타적 실현 -

이소영,Lee So-Yong 한국독어학회 2002 독어학 Vol.6 No.-

In dieser Arbeit wird versucht, das Gricesche Kooperationsprinzip und die dazu $geh\"{o}renden$ Maximen unter das Perspektiv der allgemin rnenschlichen Handlung zu revidieren. Vor allem wird in Frage gestellt, ob die Beteiligten an einem $Gespr\"{a}chsgeschehen$ unter sich in Wirklichkeit kooperieren. Um die Hypothese, dass die $Gespr\"{a}chsteilnehmer$ in der zugrunde liegenden Interaktionsebene kooperieren, zu $best\"{a}tigen$, wird auf das sogenannte iterierte Gefangenedilemma $r\"{u}ckgegriffen$M. Im $Anschlu\ss$ daran wird ein authentisches $Gespr\"{a}ch$ besonders in Hinsicht auf kooperative, sprachliche Interaktionen analysiert. Durch dieses empirsche Analyseverfahren manifestiert sieh, dass die Griceschen Kooperationsmaximen auf eine konkrete $Gespr\"{a}chssituation$ revidiert anzuwenden sind, denn in den verschiedentlich realisierten $Gespr\"{a}chen\;das\;Gespr\"{a}chsziel$ nicht als auf maximal effektiven Informationsaustausch $eingeschr\"{a}nkt$ betrachtet werden kann.

급성 조증 입원환자에 대한 항조증약물의 처방 경향

이소영,정한용,전용호,Lee, So Young Irene,Jung, Han-Yong,Jun, Yong-Ho 대한생물정신의학회 2002 생물정신의학 Vol.9 No.2

Objective:This study was performed to investigate the prescribing patterns of antimanic agents in the treatment of acute bipolar disorder inpatients in Korea from 1990 through 2000. The results will serve as the basic data for the practice guideline for the pharmacotherapy of bipolar disorder patients in Korea. Method:Retrospective chart review of bipolar disorder inpatients of Soonchunhyang Medical Center in Seoul and Chun-An was conducted for each of the year 1990, 1995, and 2000. The following data are collected ; 1) demographic data, 2) history of bipolar disorder, 3) length of hospital stay, 4) detailed drug titration records of antimanic agents and antipsychotic agents. Results:During the last decade, the frequency of lithium monotherapy was decreased obviously. Instead, more than half of the patients in 2000 were on combination therapy of lithium and anticonvulsants. Lithiumvalproate combination was the preferred strategy and the use rate of carbamazepine has been decreased. In addition, most of the patients were given antipsychotic agents during the last 10 years. And recently, atypical antipsychotics were increasingly prescribed. These changes in the field of pharmacology of bipolar disorder have resulted neither in shorter hospital stays nor lower dosages of concurrent neuroleptics. Conclusions:The results indicate the trends in the prescribing of antimanic agents for the treatment of bipolar disorder in Korea across the past 10 years. Mostly, the change seems to correspond to the international practice guideline. More systematic research is needed to find out the clinical benefits of the anticonvulsants in the real practice of treatment of bipolar disorder.

지충이(Sargassum thunbergii) 에탄올 추출물의 항균활성

이소영(So-Young Lee),송유진(Eu-Jin Song),김꽃봉우리(Koth-Bong-Woo-Ri Kim),윤소영(So-Young Yoon),김서진(Seo-Jin Kim),이소정(So-Jeong Lee),홍용기(Yong-Ki Hong),임성미(Sung-Mee Lim),안동현(Dong-Hyun Ahn) 한국식품영양과학회 2009 한국식품영양과학회지 Vol.38 No.4

Paper disc법을 통하여 항균력을 측정한 결과, 물 추출물에서는 항균효과가 나타나지 않았으나, 4 ㎎/㎖ 농도의 에탄올 추출물에서는 그람 음성균 중 S. liquefaciens, S. Typhimurium 및 P. aerogenosa에 대해 항균효과를 보였으며, 실험에 사용된 모든 그람 양성균에 대해 항균효과를 보였다. 특히, B. subtilis, C. perfringens 및 L. monocytogens에 대해 높은 항균력을 보였다. 또한 A. niger 및 P. expansum에는 항진균 효과가 없었으나 S. cerevisae에 대해서는 4 ㎎/㎖ 농도에서 항진균 활성을 보였다. 지충이 에탄올 조추출물에 대한 MIC test를 실시한 결과, 그람 음성균에 대한 MIC 값은 0.6~0.8%로 약한 항균활성을 보였으나, 그람 양성 균주 중 C. perfringens와 L. monocytogenes에 대해서는 0.01 및 0.1%에서 두 균주의 생육을 효과적으로 억제하였다. 열 및 pH 안정성 실험 결과, 지충이 에탄올 추출물은 121℃에서 15분간의 열처리와 pH 2~8 처리에도 항균활성에 변화가 없어 이들 추출물 유래의 항균물질은 열 및 pH 변화에 안정한 물질임을 알 수 있었다. 지충이 에탄올 추출물의 silica gel column chromatography 분획물을 2개 또는 3개씩 1:1(또는 1:1:1)의 비율로 혼합한 후 항균력을 측정한 결과, 클로로포름 및 에탄올 분획 혼합물과 클로로포름, 에틸아세테이트 및 에탄올 분획 혼합물에서 조 추출물 이상의 항균활성이 나타났다. Antimicrobial activity of Sargassum thunbergii was determined by paper disc assay and minimum concentration inhibitor (MIC) test. A water extract of S. thunbergii did not show the antimicrobial activity, but an ethanol extract of S. thunbergii (SHE) inhibited Serratia liquefaciens, Salmonella Typhimurium, Pseudomonas aerogenosa and all of the tested gram-positive bacteria at 4 ㎎/㎖. Especially, Bacillus subtilis, Clostridium perfringens and Listeria monocytogenes were susceptible to SHE. As the results of MIC test, SHE inhibited the growth of B. subtilis, Staphylococcus aureus and Listeria monocytogenes at concentration of 0.1~0.3%, and inhibited C. perfringens at 0.01%. In the thermal and pH stability test for SHE, antibacterial activities of SHE were maintained when the SHE was treated at 121oC for 15 minutes or under pH 2~8. SHE was partitioned in the order of n-hexane, chloroform, ethyl acetate and butanol. As the results of the MIC test for each obtained fraction, no fraction exhibited higher antibacterial activity than that of the crude SHE. However, a mixture of chloroform, ethylacetate and ethanol fractions showed higher antibacterial activity than SHE.

치과위생사의 작업특성과 근골격계 증상의 상관성

이소영 ( So Young Lee ),유병철 ( Byeng Chul Yu ),엄상화 ( Sang Hwa Urm ),권현숙 ( Hyeon Sook Kwun ),박정희 ( Jung Hee Park ),김진범 ( Jin Bom Kim ),이용환 ( Yong Hwan Lee ) 대한예방치과·구강보건학회 2011 大韓口腔保健學會誌 Vol.35 No.4

Objectives. The purpose of this study was to estimate the prevalence of musculoskeletal symptoms and work-related factors of these symptoms in dental hygienists. Methods. This questionnaire survey was conducted during May to August 2010 with 269 dental hygienists recruited as study subjects. The presence of musculoskeletal symptoms was assessed using a questionnaire of musculoskeletal symptoms from the Korea Occupational Safety Health Agency and work-related factors, and consisted of 7 job environmental factors and 4 job positions. Data analysis was performed using the chi square test and multiple logistic regression analysis using the SAS (ver 9.1) software. Results. The overall prevalence of musculoskeletal symptoms was 86.30% (233/269). The specific prevalence of musculoskeletal symptoms for different regions of the body were as follows: 64.44% in shoulders, 51.48% in legs/feet, 48.15% in waist, 47.41% in neck, 43.33% in hands/wrists/fingers, and 17.78% in arms/elbows. The related factors of musculoskeletal symptoms in dental hygienists were type of work place (OR=2.86, 95% CI: 1.07∼7.65 in dental clinics; reference group-dental hospital), number of patients per day (OR=6.10, 95% CI: 1.06∼35.04 in 15∼19 patients per day; reference group-below 10 patients per day), subjective physical burden (OR=3.06, 95% CI: 1.18∼7.94 in presence of physical burden; reference group-absence of physical burden) and location of operation (OR=9.60, 95% CI: 1.80∼51.19 in back to side position; reference group front to side position). Conclusions. More than four-fifths of the dental hygienists experienced musculoskeletal symptoms. Improvements of working environments in dental clinics, reasonable number of patients for operation, methods for reducing physical burden, correct working positions and procedures are needed to prevent musculoskeletal disease development in dental hygienists.

꽈배기 모자반 추출물 첨가에 의한 빵의 저장성 및 품질 증진 효과

이소영(So-Young Lee),김꽃봉우리(Koth-Bong-Woo-Ri Kim),송유진(Eu-Jin Song),김진희(Jin-Hee Kim),김아람(Ah-Ram Kim),김미정(Mi-Jung Kim),문지혜(Ji-Hea Moon),강희문(Hee-Moon Kang),이호동(Ho-Dong Lee),홍용기(Yong-Ki Hong),안동현(Dong-Hyun Ah 한국식품영양과학회 2008 한국식품영양과학회지 Vol.37 No.4

꽈배기 모자반 추출물을 0.01%, 0.1%, 1% 농도로 첨가하여 이들이 모닝빵의 저장성과 품질에 미치는 영향에 대하여 알아보았다. 9일간 저장하며 일반 세균수와 곰팡이수를 측정한 결과 저장기간 전반에 걸쳐 첨가 농도가 증가할수록 미생물의 생육이 억제되었으며, 수분함량의 변화에 있어서는 꽈배기 모자반 추출물 처리구가 약 5~6% 정도의 변화를 보인 반면 무처리구는 13% 정도의 큰 변화 폭을 보였다. 색도의 경우에는 추출물의 첨가농도가 높을수록 명도와 황색도는 감소하는 경향을 나타내었으며, 적색도는 이와 반대로 첨가 농도에 의존하여 증가하는 것으로 나타났다. 관능평가에서는 전체적인 호감도에서 0.01%와 0.1% 첨가구가 무처리구에 비하여 높은 점수를 받았으나 1% 첨가구에서는 가장 낮은 점수를 받았다. 이상의 결과를 종합해 볼 때 꽈배기 모자반 추출물을 0.1%정도 첨가할 경우 빵의 저장성, 품질 증진 및 관능 개선 효과가 있을 것으로 사료된다. The purpose of this study was to examine the qualities of breads added with 0.01%, 0.1% and 1% of Sargassum siliquastrum extracts (SSE). The result of total microbial count showed that breads with SSE were reduced with increasing storing time, especially bread with 1% SSE was reduced about 2 log cycle as compared to that of control. The moisture content of the bread added SSE and non-added bread were not significantly different during the early storage period, but after 9 days of storage, the moisture content of control was 13% decreased while that of the SSE added bread was decreased by only 5~6%. In the color, lightness and yellowness of bread diminished with increasing amounts of SSE in bread while conversely, redness increased. In sensory evaluation, bread containing 0.01% and 0.1% SSE were preferred than the control over total preference, while bread containing 1% SSE showed the lowest preference. These results suggest that the addition of 0.1% SSE in bread had a good effect on improving the preservation and development of quality.

위 림프종으로 오인된 원발성 위 소세포암

이소영 ( So Young Lee ),김진일 ( Jin Il Kim ),김상희 ( Sang Hee Kim ),박용재 ( Yong Jai Park ),김재광 ( Jae Kwang Kim ),우인숙 ( In Sook Woo ),이연수 ( Youn Soo Lee ) 대한내과학회 2008 대한내과학회지 Vol.75 No.6

내시경 소견에서 악성 림프종을 의심하였으나 조직학적으로 간 전이를 동반한 원발성 위 소세포암으로 진단된 환자에서 항암화학요법을 시행하여 유효한 결과를 얻었기에 문헌고찰과 함께 보고한다. Primary gastric small cell carcinoma (SmCC) is rarely encountered and has a poor prognosis, even when discovered at an early stage. A 69-year-old man presented with upper abdominal pain and melena. Endoscopic examination revealed an 8-cm-diameter submucosal tumor with ulceration high on the body of the greater curvature suggesting malignant lymphoma. Histological examination revealed a solid proliferation of small cells with hyperchromatic round nuclei and scant cytoplasm. On immunohistochemical staining, the neoplastic cells were positive for synaptophysin, EMA, and CD56. Abdominal computed tomography (CT) revealed multiple variable-sized low-attenuated masses with peripheral rim enhancement in both hepatic lobes. He was diagnosed with a pure type gastric SmCC with multiple hepatic metastasis. After systemic chemotherapy, the tumor regressed substantially on CT and endoscopy. We report a case of hepatic metastasis of gastric SmCC mimicking gastric lymphoma. (Korean J Med 75:694-699, 2008)

Lactobacillus paracasei AO356의 항비만 활성 및 안전성 평가

이소영(So-Young Lee),신동욱(Dong-Uk Shin),김승용(Seung Yong Kim),엄지은(Ji-Eun Eom),남영도(Young-Do Nam),신희순(Hee-Soon Shin),김정은(Jeong-Eun Kim),우용호(Yong-Ho Woo) 한국식품영양과학회 2021 한국식품영양과학회지 Vol.50 No.9

고지방식이로 비만을 유도한 6주령 C57BL/6J 마우스에 AO356을 1×10<SUP>7</SUP> 및 1×10<SUP>8</SUP> 농도로 10주간 투여하여 항비만 활성을 평가하였다. AO356 투여 시 식이 섭취량 변화없이 고지방식이에 의해 유도되는 체중증가 및 지방조직 무게 증가가 억제되었으며, 이상지질혈증 및 인슐린 저항성이 개선되었다. 특히 1×10<SUP>8</SUP> CFU 농도 투여군에서는 catechin 투여군과 유사한 수준의 항비만 활성을 보여 체지방 개선에 도움을 줄 수 있는 건강기능식품으로의 개발 가능성을 확인하였다. 또한 식품 원료 미생물로의 안전성을 확인하기 위해 9종 항생제에 대한 감수성을 평가한 결과, AO356은 L. paracasei 종에 대한 EFSA의 기준을 충족하였으며, 용혈성 평가에서는 γ-hemolysis 반응으로 적혈구 용혈을 일으키지 않았다. 또한 β-glucuronidase, gelatinase, urea 분해능 및 indole 생성능 등의 유효 효소와 유해 물질을 생산하지 않는 것으로 나타나 식품 원료로 사용 가능한 안전한 균주임을 확인할 수 있었다. The prevalence of obesity and associated metabolic disorders is rapidly increasing and becoming a severe health problem. Recent reports have suggested that the consumption of probiotics can be considered to be an effective approach in the treatment and prevention of obesity. In this study, we investigated the anti-obesity effect of Lactobacillus paracasei AO356 (AO356) in an obese mice model and its safety for use in functional foods. The oral administration of AO356 (10<SUP>7</SUP>∼10<SUP>8</SUP> CFU/d for 10 weeks) to mice fed a high-fat diet (HFD) significantly suppressed body weight gain and fat mass. Total plasma triglycerides, totalcholesterol, and LDL-cholesterol levels were significantly lower in mice that were treated with AO356 as compared with mice fed just an HFD. Also, the mice treated with AO356 exhibited a significant reduction of the insulin resistance index (HOMA-IR). To evaluate the safety of AO356, we conducted an antibiotics resistance test, a hemolytic test, and an enzymes (gelatinase, β-glucuronidase) activity test. The minimum inhibitory concentration (MIC) value for the 9 antibiotics specified in the European Food Safety Authority (EFSA) guidance was below the acceptable cut-off value. In the hemolysis test, AO356 showed γ-hemolysis (non-hemolytic response) on a blood agar plate. In addition, AO356 did not produce the enzymes such as gelatinase and β-glucuronidase. Taken together, these results indicate that AO356 could be safely used as a health functional food for the prevention of antiobesity.

한 여창 가객의 음악하기(musicking)

이소영(Lee, So-yong) 계명대학교 한국학연구원 2014 한국학논집 Vol.0 No.54

생애주기비용 분석을 통한 비점오염저감시설의 경제적·환경적 효과 평가

이소영 ( So Young Lee ),이정용 ( Jeong Yong Lee ),문현생 ( Hyun Saing Mun ),김이형 ( Lee-hyung Kim ) 한국물환경학회(구 한국수질보전학회) 2015 한국물환경학회·대한상하수도학회 공동 춘계학술발표회 Vol.2015 No.-