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김혜인,심기남,조형원,최주영,이신아,이민진,오다연,노선희,태정현,김성은,정혜경,김태헌,정성애,이선영,유권,문일환 이화여자대학교 의과학연구소 2010 EMJ (Ewha medical journal) Vol.33 No.2
저자들은 부주의에 의해 강알칼리를 마신 후 초기에 내시경 검사에서 식도, 위, 십이지장의 점막에서 IIa-IIa-0 정도의 손상을 보였던 환자가, 발생 9주째에 부식성 손상에 의한 상부 위장관 괴사로 진행되어 사망한 예를 경험하였기에 이에 대해 보고하는 바이다. Ingestion of corrosive substances can produce severe injury to the gastrointestinal tract and can even result in death in the acute phase. The extent and degree of damage depends on the type and amount of substances. There are occasional reports of severe contiguous injury to the esophagus and stomach caused by strong alkali ingestion in the acute phase. Usually the deaths occur within a couple of days due to multi-organ failure after ingestion of relatively much amount of agent for a suicidal attempt. But death due to late progression is very rare. We have reported a case of 60-year-old female patient who was diagnosed as corrosive esophagitis after accidental ingestion of strong alkali. Initial endoscopic findings were compatible with IIa-IIa-0(according to Zargar’s classification) in the esophagus, stomach and duodenum, respectively. After several weeks of supportive care, her subjective symptoms were much improved during she had been wating for the operation of colon interposition due to esophageal stricture. Metabolic acidosis and thrombocytopenia developed abruptly probably due to upper gastrointestinal tract necrosis and she died when 60 days had passed after the occurrence of initial esophageal injury.