뇌졸중 환자에서 호흡기능과 연하장애의 연관성

양혜은,박윤길,김선미 대한연하장애학회 2014 대한연하장애학회지 Vol.4 No.1

Objective: Dysphagia is a very common complication of stroke and is can be a marker of poor prognosis. In addition altered respiratory function is also observed in stroke patients. The purposes of this study are to find out correlations between dysphagia and respiratory function, and if specific parameter of respiratory function can screen patients at high risk of aspiration. Method: 37 adult stroke patients were enrolled (18 in aspirated group, 19 in non-aspirated group). All patients underwent video fluoroscopic swallowing study (VFSS) and pulmonary function test (PFT) including forced vital capacity (FVC), forced expiratory volume at one second (FEV1), and peak cough flow (PCF). Diaphragmatic motion during breathing was measured through fluoroscope and end-tidal CO2 (EtCO2) was measured on resting state. Patients were separated into two groups in term of aspiration on VFSS. Result: The FVC of aspirated group (48.5±14.1%) was significantly lower than that of non-aspirated group (57.2±9.95%) (P=0.036). The FEV1 of aspirated group (43.3±15.3%) was also significantly lower than that of non-aspirated group (53.8±15.6%) (P=0.047). Other parameters and patient characteristics did not show significant differences. Conclusion: FVC is considered an important factor to expect aspiration on swallowing in stroke patients. So PFT including FVC and FEV1 could be a useful method to screen stroke patients at high risk of aspiration.

내가 옆집 애라구?

양혜은 샘터사 2003 월간 샘터 Vol.34 No.3

두께변화에 따른 다공성 역 오팔구조 WO₃ 박막의 전기변색 특성 비교

양혜은,서현진,유정훈,김동인,이지원,정낙현,남상훈,부진효 한국진공학회 2018 한국진공학회 학술발표회초록집 Vol.2018 No.2

Galangin 및 양강추출물의 KBrO3 유도 DNA 및 염색체 손상에 대한 보호효과

양혜은(Hye Eun Yang),허문영(Moon Young Heo) 대한약학회 2010 약학회지 Vol.54 No.6

The aim of this study was to evaluate the in vivo effect of galangin and the 70% ethanolic extract of Alpinia officinarum (AO) toward KBrO3-induced DNA and chromosomal damage in mice. Galangin and AO inhibited the formation of 8-hydroxy-2'-deoxyguanosine (8-OH2'dG) as an indicator of DNA oxidative damage in the liver cell. Galangin and AO showed the inhibitory effect on the formation of DNA single strand break in the splenocyte by single cell gel electrophoresis (SCGE) assay and also inhibited micronucleated reticulocyte (MNRET) formation of peripheral blood in tail blood of mice. Vit-E revealed antigenotoxic effects in DNA and chromosome levels, but galangin was more potent active compound compare to vit-E under our experimental conditions. The results suggest that the extract of Alpinia officinarum containing galangin can modify the oxidative DNA and chromosomal damage and may act as chemopreventive agent against oxidative stress in vivo.

구두닦이의 회의근의 결절종으로 인한 후골간신경마비

정수진,양혜은,전하라,김선미,김대현,박홍석 대한근전도전기진단의학회 2016 대한근전도 전기진단의학회지 Vol.18 No.1

Posterior interosseous nerve (PIN) is a deep muscular branch of radial nerve, and non-traumatic paralysis of this nerve is relatively rare. This case reports that shoeshine man had complained of finger extensor muscles weakness caused by PIN nerve compression because of ganglion at the edge of supinator muscles. In magnetic resonance imaging, there was 1.3 x 0.6 x 1.6 cm-sized ganglion occurring at the edge of supinator muscles and compression of PIN nerve. This ganglion may also be associated with his occupational factor. After resection of ganglion, his finger extensor weakness was improved, but still remained.

Lesion Characteristics of Chronic Dysphagia in Patients With Supratentorial Stroke

장솔,양혜은,양희승,김대현 대한재활의학회 2017 Annals of Rehabilitation Medicine Vol.41 No.2

Objective To analyze the relationship between brain lesion location and type of chronic dysphagia in patients with supratentorial stroke.Methods Data from 82 chronic stroke patients who underwent videofluoroscopic swallowing studies at >6 months after an initial stroke event were retrospectively analyzed. Delayed oral transit time, delayed pharyngeal transit time, and the presence of aspiration were extracted. A voxel-based lesion symptom mapping (VLSM) analysis was used to correlate types of dysphagia with specific brain lesions.Results VLSM identified several clusters of voxels that significantly correlated with type of dysphagia. Delayed oral transit time mainly correlated with lesions in the left inferior frontal lobe and precentral gyrus; delayed pharyngeal time mainly correlated with lesions in the right basal ganglia and corona radiate; and aspiration was mainly correlated with lesions in the putamen.Conclusion Understanding the association between lesion location and dysphagia in chronic stroke patients is an important first step towards predicting permanent dysphagia after stroke. Improved understanding of the neural correlates of dysphagia will inform the utility of interventions for its treatment and prevention after stroke.

Effects of Lumbar Strengthening Exercise in Lower-Limb Amputees With Chronic Low Back Pain

신민경,양희승,양혜은,김대현,안보람,권협,이주환,정숙,최현철,윤선궁,안동영,심우섭 대한재활의학회 2018 Annals of Rehabilitation Medicine Vol.42 No.1

Objective To analyze the effect of lumbar strengthening exercise in lower-limb amputees with chronic low back pain. Methods We included in this prospective study 19 lower-limb amputees who had experienced low back pain for longer than 6 months. Participants were treated with 30-minute lumbar strengthening exercises, twice weekly, for 8 weeks. We used the visual analog scale (VAS), and Oswestry low back pain disability questionnaire, and measured parameters such as iliopsoas length, abdominal muscle strength, back extensor strength, and back extensor endurance. In addition, we assessed the isometric peak torque and total work of the trunk flexors and extensors using isokinetic dynamometer. The pre- and post-exercise measurements were compared. Results Compared with the baseline, abdominal muscle strength (from 4.4±0.7 to 4.8±0.6), back extensor strength (from 2.6±0.6 to 3.5±1.2), and back extensor endurance (from 22.3±10.7 to 46.8±35.1) improved significantly after 8 weeks. The VAS decreased significantly from 4.6±2.2 to 2.6±1.6 after treatment. Furthermore, the peak torque and total work of the trunk flexors and extensors increased significantly (p<0.05). Conclusion Lumbar strengthening exercise in lower-limb amputees with chronic low back pain resulted in decreased pain and increased lumbar extensor strength. The lumbar strengthening exercise program is very effective for lower-limb amputees with chronic low back pain.

다양한 크기를 갖는 폴리스틸렌 구를 이용한 염료감응형 태양전지의 전류밀도 향상 연구

남상훈,유정훈,김동인,양혜은,부진효 한국진공학회 2017 한국진공학회 학술발표회초록집 Vol.2017 No.2

로봇형 보조기 착용시 경사로에 따른 LSTM 기반의 보행패턴인식

김태희,이종명,권익중,심우섭,안동영,양혜은,최준호,박재환,손충현,김태환 한국재활복지공학회 2023 재활복지공학회논문지 Vol.17 No.3

In this study, the joint angle difference and the classification accuarcy of gait phase detection according to the ramp in the gait with the robotic orthotics were analyzed. Nine subjects were recruited, put on the robotic orthosis, and walked uphill, downhill, and level ground five times, respectively. During walking, three inertial sensors were attached to the human limb’s thigh, calf, and foot, and two inertial sensors were attached to the thigh and calf parts of the robotic orthotisis to measure the ankle and knee angles, respectively. The measured joint angles from the robotic orthotisis and the body limb were compared using SPM(Statistic Parameter Mapping) and trained to classify whether the stance phase or swing phase using LSTM(Long Short-Term Memory) classifier. As a result, the differences in the joint angle between the robotic orthotisis and the body limb were observed in the mid-stance and the mid-swing phase during gait. In addition, misclassification was observed during the change of stance phase and swing phase period. In particular, it was found that the number of misclassifications increased as the difference in joint angle between the robotic orthotisis and the body limb increased in the stance phase. Through this, the difference of joint angle between the robotic orthotisis and the body limb, which occurs along the ramp, affects the accuracy of gait phase detection. It is supposed to develop a phase detection and control algorism considering the effect of classification accuracy due to the difference in joint angle according to the slope change. 본 연구에서는 로봇형 보조기의 보행에서 경사로에 따른 관절각의 차이를 확인하고, 그 차이가 보행단계의 검출에 미치는 영향에 대해 분석하고자 하였다. 9명의 피험자를 모집하여 로봇형 보조기에 탑승시킨 후 각각 오르막 5회, 평지 5회, 내리막 5회의 보행을 진행하였다. 보행하는 동안 3개의 관성 센서를 신체의 대퇴, 종아리, 발에 부착하였고, 2개의 관성 센서를 로봇형 보조기의 대퇴부, 종아리부에 부착하여 로봇형 보조기와 신체의 발목 및 무릎각도를 측정하였다. 측정된 관절각도는 SPM(Statistic Parameter Mapping)을 사용하여 로봇형 보조기와 신체의 관절각을 비교하였고, LSTM(Long Short-Term Memory) 분류기를 사용하여 입각기와 유각기의 구분을 위하여 학습되었다. 그 결과, 보행을 진행하는 동안 중간 입각기와 중간 유각기에서 착용형 로봇형 보조기와 신체간의 관절각 차이가 확인되었다. 또한, 보행 단계의 검출 결과, 입각기와 유각기간 변화하는 동안 오분류가 확인되었다. 특히, 입각기 구간에서 로봇형 보조기와 신체의 관절 각 차이가 커짐에 따라 오분류의 횟수가 증가하는 것으로 나타났다. 이를 통해 본 연구에서는 경사로에 따라 발생하는 로봇형 보조기와 신체의 관절 각 차이가 보행 단계를 검출하는 데에 영향을 주는 것을 확인하였으며, 추후 보행단계 제어시 경사로에 따른 인체 분절과 유격으로 인한 분류 정확도의 영향을 고려하여 제어알고리즘을 개발할 것을 제안한다.

전기변색 내구성이 향상된 이산화티타늄/산화니켈 이종구조 제작 및 특성 분석

정낙현,유정훈,김동인,황기환,남상훈,양혜은,이지원,서현진,부진효 한국진공학회 2017 한국진공학회 학술발표회초록집 Vol.2017 No.8