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- 저자 : 송제일 (검색결과 9 건)
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송제일,김유영,강석영 대한천식알레르기학회 1981 천식 및 알레르기 Vol.1 No.2
Cows milk allergy can be s aid to be present when the immunologic re a,ctions to c m v miik are associ ated with c IinicaI symptoms. Despite of its low incidence, the decrease in breast feeding in most developed ccuntries has made cows milk allergy an important ca se cf infant morbidity and one cf the best know n and most frequently encontered problems in current infant feeding practices. With the incre zse of cows milk feeding in Korea, it is thought that cows milk allergy might be one of the major prcblems in inf snt feeding. So we show a case of cows milk allergy manif ested by erythematous periorbital angioedem a and cows milk allergy is discussed with review of 1 iter atures.
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Dose- and Time-Related Effects of Pilocarpine Mouthwash on Salivation
송제일,박조은,김혜경,김미은,김기석 대한안면통증∙구강내과학회 2017 Journal of Oral Medicine and Pain Vol.42 No.3
Purpose: Pilocarpine as a salivation stimulant in pill form has mostly been used to relieve oral dryness for xerostomic patients but its use may often be limited due to variable side effects from systemic absorption. Therefore, the purpose of this study was to investigate the effects of pilocarpine mouthwash on salivation according to the variable concentration and duration for healthy volunteers. Related adverse effects and subjective assessment on its effects on salivation were also examined. Methods: This study was performed as placebo-controlled, double-blind, randomized clinical trial. Thirty healthy volunteers (male=23, mean age=22.2 years) were randomly allocated to 6 groups with the different concentration of pilocarpine mouthwash (placebo, 0.1%, 0.5%, 1.0%, 1.5%, and 2.0%). The whole experiment consisted of 3 sessions according to the duration of mouthwash, i.e., 1, 3, and 5 minutes with the mean wash-out period ≥2 days between the sessions. Unstimulated whole saliva was collected before and after gargling with a mouthwash. Results: Salivation of the higher concentration groups ≥1% significantly increased than those of lower concentration group. The application period of mouthwash did not cause any changes of salivary flow rate at the higher concentrations ≥1.0%. The lower concentrations of 0.5% and 0.1% had no effects on salivation even after 5-minute mouthwash. There was no significant difference between blood pressure and pulse rate before and after use of mouthwash. Conclusions: From the results of the current study, pilocarpine mouthwash with at least 1.0% concentration more than a minute might be clinically effective in salivation without any serious side effects. Dose of mouthwash rather than duration seems to be a critical factor to salivation.
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국내 치과대학병원에서 시행한 단기 금연진료에 대한 조사
송제일,이기호,김미은,김기석,Song, Je-Il,Lee, Gi-Ho,Kim, Mee-Eun,Kim, Ki-Suk 대한안면통증구강내과학회 2010 Journal of Oral Medicine and Pain Vol.35 No.4
Smoking has been identified not as a major risk factor for circulatory and respiratory diseases but also as causes of various oral diseases. A number of clinical studies and regional health surveys have found an association between smoking and poor oral health status and between smoking and prognosis of dental treatments. However, there is few studies about status of smoking cessation treatment and policies in dentistry in Korea. The purpose of this study was to investigate the smoking patterns of outpatients and outcomes of short-term smoking cessation treatment in dental hospitals in Korea and, subsequently, to seek further smoking cessation services in dentistry. This study was sponsored by Korean Dental Association (KDA) and department of culture and welfare. 825 dental patients were voluntarily participated in a 4-week smoking cessation program with nicotine patch and 297 participants of them completed on smoking-related questionnaires. All participants were recruited from outpatients of 11 dental university hospitals (primarily in the department of oral medicine, oral surgery and periodontology) in Korea during 3-month period from October 2009 to January 2010. The Questionnaires included demographics, duration of smoking, heavy smoking index (HSI), number of thinking of quit smoking, duration of stop smoking and reasons to smoking, awareness of smoking effects on oral health, and their success rate after 4 weeks of nicotine patch program was investigated. The statistical analysis was carried by SPSS version 18.0 program and Chi-square test. According to the results of this study, male in their 30s to 50s were the most prevalent of all the participants and duration of smoking increased with age. Attempt rate to quit smoking (Quit smoking) was the highest in 30s and 40s with duration of quit smoking ranging 1 to 3 months. Emotional stresswas the most frequently reported reason for smoking, followed by habit and pleasure in order. All age group showed high HIS over 71% and awareness of smoking effects on oral diseases such as oral soft tissue diseases, periodontal diseases and dental caries was found relatively high (50~60%) Periodontal implant was the main reason for participation in the smoking cessation services in dental clinics and the success rate of, 4-week nicotine patch program of all the participants was 29.4%, extremely low compared to that of medical clinics. Systemic education for dentists to be able to provide interventions to quit smoking including counseling with the 5As'and development of available measures for smokers is needed as considered that the low success rate of the smoking cessation services in dentistry could be explained mainly by lack of dentists' strategies, experience and attention. Awareness and attention of dentists should be emphasized and their participation be encouraged by long-term, multidisciplinary policies such as establishment of insurance fee, which would made a considerable progress in preventing smoking-related oral diseases and promoting public oral health.
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내시경적 (內視鏡的) 역행성 췌담관조영술의 (膵膽管造影術) 합병증에 (合倂症) 대한 Gabexate mesilate ( FOY ) 의 예방적 (豫防的) 효과
송인성(In Sung Song),김정용(Chung Yong Kim),윤영범(Yong Bum Yoon),배순기(Soon Kie Bae),송제일(Je Il Song) 대한소화기학회 1981 대한소화기학회지 Vol.13 No.2
N/A The development and prevalence of endoscopic retrograde cholangiopancreatography(ERCP) has resulted in great progress in the diagnosis of the disease of the pancreas, and biliary tract. At the same time, however, the rise of serum amylase level has been often point out as the complication of ERCP. To assess the effect of synthetic protease inhibitor, Gabexate mesilate(FOY), in hyperamylasemia following ERCP, the authors carried out a controlled trial in 39 patients who were underwent ERCP under the impression of pancreatic or biliary system disease. Of them 20 patients were allocated to FOY@ treated group and 10 patients to control group. The following results were obtained: 1) There was no significant difference in serum amylase level between FOY treated group and control group before ERCP, however significant difference was observed in seram amylase level at 2 hour and 2 day after ERCP between FOY treated group and control group Before ERCP the serum amylase level was 107. 6 45. 1 I.U./dl in control group and 105. 7+-42.1 I.U./dl in FOY treated group.At 2hour after ERCP the serum amylase level was 186.7 +-150.1 I.U./dl in control group and 103.2+-47.9 I.U./dl in FOY treated group. On 2nd day after ERCP, the serum amylase level was 167.7+-84. 1 I.U,/dl in control group and 109.6+-59.1 I.U./dl in FOY treated group 2) The change in serum amylase levels at 2 hour and 2 day after ERCP by the extent of visualization showed a tendency that a greater extent of visualization was associated with a higher incidence of serum amylase levels. Such a tendency was more pronounced in control group and the mean serum amylase level was significantly higher in the control group. 3) FOY did not cause any serious side effect such as shock, fall of blood pressure, itching, eruption, chest pain etc. in all cases. 4) There was some report that FOY has a relaxant action on the Oddis sphincter and helps the cannulation to the opening of Papilla of Vater, however it more depended upon the skill of the endoscopist, anatomical variation of the Papilla of Vater and FOY did not give any great advantage to the cannulation.
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HBsAg 이 양성인 만성 간질환 환자에서 중합효소 연쇄반응법을 이용한 HBV DNA 검출의 의의
송제일(Je Il Song),유권(Kwon Yoo),이효석(Hyo Suk Lee),김정룡(Chung Yong Kim) 대한내과학회 1991 대한내과학회지 Vol.40 No.3
N/A The identification of serum HBV DNA is very important for the assessment of the disease activity in persistent infection, for the evaluation of the infectivity of an individual's blood, and for monitoring the therapeutic trials of antiviral agents. The dot blot, however, has limited sensitivity and sometimes inconsistent with other serological markers and clinical settings. Using the most important recent advance in molecular biology, the novel polymerase chain reaction (PCR), specific DNA sequences can be amplified more than a million-fold in a few hours and with this technique the detection of the extreme low level of DNA is possible. This study was to determine the detection level and sensitivity of the PCR-Southern blot analysis for the detection of serum HBV DNA in comparison with dot blot analysis and to investigate the persistence of HBV replication in 66 HBsAg-positive chronic liver disease patients with different sets of HBV serological profile; group 1) 33 HBsAg-, anti-HBc- and HBeAg-positive patients, group 2) 33 HBsAg-, anti-HBc- and anti-HBe-positive patients. The results were summarized as following; The detection levels of HBV DNA by dot blot, PCR-ethidium bromide staining, PCR-Southern blot were 1 pg, 10-2 pg, 10-5 pg., respectively. The detection rates of HBV DNA by dot blot, PCR-ethidium bromide staining, PCR-Southern blot were 84.8%, 93.9% and 100% in group 1, 42.4%, 63.6% and 72.7% in group 2, respectively. In conclusion, we confirmed that the PCR-Southern blot analysis is much more sensitive than the dot blot analysis in detecting the HBV DNA in the sera of patients with chronic liver disease. Presence of HBV DNA by the PCR highly suggested that active viral replication is still going on in most patients with chronic HBsAg-positive liver disease irrespective of HBeAg/anti-HBe status.
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