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한양방 동시 치료를 통하여 회복되지 않은 양측성 돌발성 난청 환자 1례
송민경,홍승욱,Song, Min-Kyung,Hong, Seung-Ug 대한한방안이비인후피부과학회 2010 한방안이비인후피부과학회지 Vol.23 No.1
Back ground & Objectives : Bilateral sudden sensorineural hearing loss(SSNHL) is very rare disease. This is the first case report in the oriental medical literature. This study describes a case of bilateral SSNHL with incomplete recovery. Methods : We treated 1 patient who had SSNHL sequentially in both ears. He received oriental and western medical treatments for more than 2 weeks and measured the hearing recovery. For diagnosis on this case, pure tone audiometry was used. The degree of improvement was evaluated by Siegel's Criteria. Results & Conclusions : This patient discharged without hearing improvement. For bilateral SSNHL patients, the result of treatment is important for their qualities of life. But the recovery rate of hearing in bilateral SSNHL is lower than unilateral SSNHL. The oriental medical therapy had some theraputic effects on SSNHL and the theraputic effects on bilateral SSNHL requires further study.
송민경,홍승욱,Song, Min-Kyung,Hong, Seung-Ug 대한한방안이비인후피부과학회 2012 한방안이비인후피부과학회지 Vol.25 No.3
Objectives : The purpose of this study is to evaluate students' satisfaction on participation learning using role-play in clerkship of Oriental Ophthalmology & Otolaryngology department. Methods : In 2012, 93 sixth grade students undergoing Oriental Ophthalmology & Otolaryngology clerkship were included in this study. The students listened to a lecture on nasal disease. And three days later, Students were randomly divided into two groups, doctor or patient, and performed role-play in their role. After role- play, they completed the questionnaire, the questionnaire was composed of 16 items. Results : Mean of total satisfaction score was 4.14. Mean of interest and appropriacy score was 4.48, mean of usefulness satisfaction was 3.93. There was no significant difference in mean scores by the role groups. Students evaluated the role-play in clerkship positively. Conclusions : Students evaluated the role-play that it was interesting and useful educational tool in clerkship. It is necessary to undergo further trials and complement programs to upgrade the quality of Oriental medical clerkship.
알레르기 비염 동물 모델에서 유산균 발효 신이(辛夷)의 효과
송민경,홍승욱,Song, Min-Kyung,Hong, Seung-Ug 대한한방안이비인후피부과학회 2013 한방안이비인후피부과학회지 Vol.26 No.1
Objectives : We aimed to determine therapeutic effects of probiotics-fermented Magnolia denudata(MD) in the allergic rhinitis model mice. Methods : Polyphenol production, DPPH radical scavenging activity and NO inhibition of fermented MD by different bacterial strains were evaluated to select the one that is most suitable for fermentation. Thirty C57BL/6 mice were divided randomly into 5 groups as follows: normal group, ovalbumin(OVA)-treated plus water fed(CON group), OVA-treated plus unfermented MD fed(UMD group), OVA-treated plus fermented autoclaved MD fed(A-FMD group) and OVA-treated plus fermented unautoclaved MD fed(FMD group). After 9 weeks, we observed changes in the blood cell count, OVA-specific IgE level, nasal rubbing, nasal mucosal tissue and body weight. Results : Extract of MD fermented by Bifidobacterium breve(BB) for 48 hours showed the highest anti-oxidant activity and anti-inflammatory activity out of all the other bacterial strains. The number of eosinophil count in A-FMD, FMD group and platelet count in FMD group showed statistically significant decrease(p<0.05). OVA-specific IgE level decreased in all 3 experimental groups, significantly in UMD and A-FMD group. Nasal symptoms were attenuated in all 3 experimental groups, statistically significant in A-FMD and FMD group (p<0.05). Histologically, infiltration of eosinophils into the nasal mucosa decreased in all 3 experimental groups, especially marked decrease in FMD group. Conclusions : According to the above results, it is considered that probiotics-fermented Magnolia denudata has inhibitory effects on the allergic rhinitis animal models.
송민경,공승대,오은하,윤철훈,김윤신,임호섭,Song, Min-Kyung,Kong, Seung-Dae,Oh, Eun-Ha,Yoon, Hun-Cheol,Kim, Yoon-Shin,Im, Ho-Sub 한국환경보건학회 2010 한국환경보건학회지 Vol.36 No.3
In preparative anti-corrosive coating experiments, polyaniline was obtained by reacting an oxidizing agent with the monomer aniline. Further, the primer coating was prepared using a variety of widely-used materials such as urethane resin. For the top coating, epoxy resin and acrylic urethane resin were used. Characteristics of the coatings were assessed according to KS and ASTM specifications, and the structure of the polyaniline was characterized using FT-IR and TGA. For analysis of anti-corrosive properties in salt-spray experiments, measurements of the oxidation state of iron and surface atomic analysis were conducted using XPS and SEM-EDX. Unlike general anti-corrosive coatings which exhibit anti-corrosive effects only as a primer coating, the anti-corrosive coatings using polyaniline as the anti-corrosive pigment showed a marked synergistic effect with the top coatings. In other words, the top coatings not only produce a fine view effect, but also increase, through interaction with the primer coatings, the resistance to diffusion of corrosive factors from the external environment. It was also found that, unlike the heavy metal oxide-forming layer of the passive barrier alone, the polyaniline anti-corrosive pigment oxidized iron at the interface with the iron substrate to form a passive barrier in the oxidic layer, and itself formed a potential barrier layer with anti-corrosive factors from the external environment. Although the passive layer was damaged, the damaged area did not become completely oxidized iron; on the contrary, it showed a tendency to reduction. This can be interpreted such that a passive layer is formed again on the damaged area, and that at the same time there is a tendency to self-healing.
항암제를 투여한 HeLa와 OVCAR-3 세포주에서 Cytokeratin 18-Asp(396) (M30) 항체를 이용한 항암제 감수성의 측정
송민경 ( Min Kyung Song ),박상호 ( Sang Ho Park ),곽현성 ( Hyun Sung Kwack ),류기성 ( Ki Sung Ryu ),한구택 ( Ku Taek Han ) 대한산부인과학회 2010 Obstetrics & Gynecology Science Vol.53 No.1
Objective: The aim of this study was to detect the levels of M30-antigens as a biomarker of apoptosis in cells and their culture media after treatments with anticancer drugs as a preclinical study. Methods: After HeLa and OVCAR-3 cells were treated respectively with paclitaxel, cisplatin, and camptothecin, the harvested cells were stained sequentially with M30 monoclonal antibodies and propidium iodide (PI). Afterwards, they were analyzed using a FACScan flow cytometer and observed under an immunofluorescence microscope for M30-FITC immunofluorescences. Levels of M30 antigens were also detected in their culture media using M30-Apoptosense ELISA kit. Results: The levels of M30-FITC immunofluorescences were elevated in both cell lines after each drug treatments compared with those of control cells. The levels of M30 antigens detected by ELISA in media culturing each cell line treated with each of drugs were elevated compared with those of control cells. Conclusion: This study suggests that M30-antigens representing chemotherapy induced apoptosis may be a useful biomarker for predicting and monitoring the response of neoadjuvant chemotherapy in patients with gynecologic cancers.
자연재난이 관광수지에 미치는 파급효과분석 : 자연자원중심지와 문화 자원중심지를 대상으로
송민경(Song Min kyung),김상혁(Kim Sang hyuck) 대한관광경영학회 2017 관광연구 Vol.32 No.7
본 연구의 목적은 국가의 관광자원보유수준(자연자원, 문화자원)에 따라 자연재난 유형별 관광산업에 미치는 영향의 평균적인 크기와 지속기간을 측정하고자 하였다. 본 연구를 위한 자료의 수집은 52개 국가를 대상으로 1995년부터 2015년까지의 자연재난(지진, 폭풍, 홍수), 관광수지, 실질국내총생산, 실질실효환율 등의 2차 자료를 수집하여 실증분석에 사용하였다. 또한 국가의 관광자원 유형을 자연자원과 문화자원 보유수준을 기준으로 집단분류하고 자연재난은 강도를 기준으로 더미 변수화 하여 사용하였다. 본 연구의 분석결과를 살펴보면, 국가의 관광자원유형 중 자연자원 보유수준이 높은 집단은 자연재난 중 지진의 발생만이 관광산업에 영향을 미치는 것으로 나타났다. 그러나 자연자원 보유수준이 낮은 집단의 경우 폭풍과 지진의 발생 시에 관광산업에 영향을 미치는 것으로 나타났다. 또한, 국가의 관광자원 유형 중 문화자원의 보유수준이 높은 집단은 자연자원 보유수준이 높은 집단과 마찬가지로 지진의 발생 시에만 관광산업에 영향을 미치는 것으로 나타났다. 반면, 문화자원 보유수준이 낮은 그룹의 경우 폭풍의 발생 시에만 관광산업에 영향을 미치는 것으로 나타났다. 결론적으로, 자연재난 유형별 관광산업에 미치는 영향은 국가의 관광자원 유형 및 보유수준과 자연재난 유형에 따라 다른 특성을 갖는 것으로 나타났다. 본 연구의 결과는 관광자원 유형 및 보유수준에 따른 자연재난 유형별 파급효과의 평균적 크기와 지속기간을 규명하여 맞춤형 재난 대응전략수립 시 선행되는 정보를 제공하였다. The purpose of this study is to examine the average scale and duration of each type of natural disaster’s effect on the tourism balance in accordance with a country’s type and level of tourism resources. The data used for this study were the annual panel data from 1995 to 2015 of 52 countries. Types and level of natural disasters, tourism balance, real GDP, and real exchange rate in each sample country were gathered from various secondary data bases for this study. In addition, the sample were divided by two groups based on level of tourism resources in each sample country. The empirical results shows a natural disaster’s effect on the tourism industry differed depending on the type and level of tourism resource in a country. This study would provide useful information required to establish tailor-made natural disaster response strategies for each types of disaster and for each country that have different characteristics of tourism resources.
온라인에서의 레스토랑 구전정보 작성자와 구전평가 방향에 따른 레스토랑 방문의도와 정보 신뢰도 차이 연구
송민경(Min Kyung Song),윤혜현(Hye Hyun Yoon) 한국조리학회 2013 한국조리학회지 Vol.19 No.2
The arrival and expansion of the Internet has extended consumers` options and has provided consumers` opportunities to offer their own consumption. Through a laboratory experiment, we investigated questions: 1) do consumers trust the accuracy of reviews posted by anonymous reviewers or experts and 2) do readers trust negative and positive reviews equally? The messages were created as a form of 4 scenarios for this study. The statistical analysis was conducted using SPSS Win(v.16.0) for descriptive analysis, and t-test. Our results from a 2(positive reviews vs. negative reviews)*2(consumer vs. expert) experiment design showed that there was a significant difference between consumers` review and experts` one in restaurant visit intention(p<.001) and information credibility(p<.001). Also, between positive review and negative one, significant difference was found in restaurant visit intention(p<.001) and information credibility(p<.01). Other results, limitations and future research directions were also discussed.