205. 수종의 항암제가 인체과립백혈구의 화학주성에 미치는 영향에 관한 실험적 연구

박신희,조장환,이경식 대한외과학회 1989 대한외과학회 학술대회 초록집 Vol.1989 No.11

초기결함을 갖는 측면부재의 충돌 해석 및 실험 ( Crashworthiness Analysis and Experiment of Side Rails with Initiators )

박신희,강신유,한동철 대한기계학회 1994 대한기계학회 춘추학술대회 Vol.- No.-

배려의 관점에서 지역아동센터 구성원 간 상호작용 분석: ‘배려관계’ 형성의 가능성과 한계

박신희,김민성 한국아동교육학회 2022 아동교육 Vol.31 No.4

The purpose of this study is to understand the interaction between members in the child community center from the perspective of 'caring'. The long-term observation and participant interviews of the interaction between the members in the two child community centers were analyzed through continuous comparison method from hermeneutic qualitative approach. From the result, it was found that the child community center is an institution with various possibilities to promote a caring relationship among members. First, the fact that members of the child community centers can meet and interact for a long time provided an opportunity to experience and practice 'caring'. In addition, at the child community center, children were able to experience and learn various types of caring by interacting with multi-grade children, center heads, welfare teachers, part-time teachers, and volunteers with various backgrounds and specialties. On the other hand, there exist factors that hinder the formation of a caring relationship: 1) the strong connection of existing children that makes it difficult to understand other children, 2) the excessive workload of full-time teachers, 3) the emphasis on their role or teaching rather than the acceptance of children by teachers, and 4) the short-time commitment by part-time teacher or voulnteers. 본 연구는 지역아동센터 내 구성원 간의 상호작용을 ‘배려’의 관점에서 이해하고자 2개의 지역아동센터의 일상 및 활동 속에서 구성원 간의 상호작용을 장기간 관찰하고 참여자들의 경험을 면담을 통해 살펴보았다. 해석학적 질적접근과 지속적 비교방법을 통해 아동 간 상호작용, 상근교사 및 비상근 교사와 아동 간의 상호작용을 분석하였다. 그 결과, 지역아동센터가 구성원 간의 배려관계를 촉진하는 다양한 가능성을 지닌 기관이라는 것을 알 수 있었다. 먼저 지역아동센터에서 구성원들이 오랜 기간 만남과 교류를 가질 수 있다는 것이 ‘배려’를 경험하고 실천할 기회를 제공하고 있었다. 그리고 지역아동센터에서 아동들은 다학년의 아동들, 센터장과 생활복지사 선생님, 다양한 배경과 전문성을 가진 비상근 교사와 자원봉사자와 상호작용하며 다양한 배려를 경험하고 배울 수 있었다. 한편, 배려관계 형성에 장애가 되는 요소로는 다른 아동을 수용하는 것을 힘들게 만드는 기존 아동들 간의 관계망, 상근 교사의 과다한 업무, 교사들이 아동보다는 자신의 역할이나 아동지도를 중시하는 것, 비상근 교사와의 짧은 만남 등을 확인할 수 있었다. 이러한 결과를 토대로 ‘배려관계’ 형성과 관련하여 지역아동센터가 가진 가능성과 한계 및 지역아동센터에 필요한 지원책을 논의하였다.

에폭시 말단기를 함유한 macromonomer 의 리빙음이온 중합

박신희,류상욱 한국공업화학회 2014 한국공업화학회 연구논문 초록집 Vol.2014 No.1

리빙 음이온 중합은 조절된 분자량, 분자량 분포 및 계산된 조성을 합성 할 수 있는 방법으로 고차구조제어 고분자 합성에 폭넓게 이용되고 있다. 본 연구에서는 poly(ethylene glycol) methyl ether (PEGME)와 epichlorohydrin (ECH)의 Willamson반응을 이용하여 glycidyl ether macromonomer를 합성하였다. 고진공 유리장치 내에서 음이온 개시제인 diphenylmethyl potassium (DPM-K)을 사용하여 합성된 macromonomer의 에폭시기를 개환하였으며, 50°C에서 3일간 중합한 뒤 styrene oxide (SO)를 첨가하여 추가로 10일간 중합시켜 블록공중합체를 합성하였다. 합성된 고분자는 1H-NMR, FT-IR, GPC 측정을 통해 성분비 및 작용기, 분자량, 분자량 분포를 확인하였다. 그 결과 음이온 리빙중합이 성공적으로 진행 된 것을 확인하였고 계산치와 유사한 조성의 블록공중합체를 얻을 수 있었다.

에폭시 말단기를 함유한 macromonomer의 합성 및 리빙음이온 중합 Synthesis of macromonomer containing epoxy-end functional group and living anionic polymerization

박신희,류상욱 한국공업화학회 2015 한국공업화학회 연구논문 초록집 Vol.2015 No.1

리빙 음이온 중합은 조절된 분자량, 분자량 분포 및 계산된 조성을 합성 할 수 있는 방법으로 고차구조제어 고분자 합성에 폭넓게 이용되고 있다. 본 연구에서는 촉매 tin(IV) chloride를 사용하여 poly(ethylene glycol) methyl ether (PEGME)와 epichlorohydrin (ECH)으로 구성된 macromonomer를 합성하였다. 합성된 macromonomer를 고진공 유리장치 내에서 음이온 개시제인 diphenylmethyl potassium (DPM-K)을 사용하여 반응을 개시하였으며, 50°C에서 3일간 중합하였다. 합성된 고분자는 ¹H-NMR, FT-IR, GPC 측정을 통해 성분비 및 작용기, 분자량, 분자량 분포를 확인하였다. 그 결과 음이온 리빙 중합이 성공적으로 진행된 것을 확인하였고 계산치와 유사한 조성의 고분자가 중합되었다.

F-167 Clinical course and outcome of immunoglobulin G4 related lung disease

박신희,송준선,채은진,송태준,김명환,송진우 대한결핵 및 호흡기학회 2016 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.121 No.-

Background: There is few data on clinical features, courses and outcome of IgG4-related lung disease (IgG4-RLD). The purpose of this study is to investigate clinical course and outcome of IgG4-RLD. Methods: Clinical data was retrospectively analyzed in 191 patients with IgG4-related disease diagnosed from March, 2002 to August 2016 at Asan Medical Center. The characteristics of IgG4-RLD were compared to IgG4-RD without lung involvement. Results: Median follow-up was 25 months and lung involvement was identified in 41 (21.5%) patients. Age and sex were similar between IgG4-RLD and IgG4-RD without lung involvement but the number of ever-smoker was significantly higher in IgG4-RLD (75.6 vs. 58%, p<0.05.). Serum IgG and IgG4 level, anti-nuclear antibody and rheumatoid factor was not statistically different between groups. Baseline pulmonary function test was obtained in 31 patients; 11 (35.3%) had obstructive pattern and 4 (12.9%) had restrictive pattern. Solid nodular type (39.0%) was the most commonly found on CT, followed by alveolar consolidation (24.4%), alveolar interstitial (14.6%), bronchovascular (12.2%) and round shape GGO (9.8%) type. Median treatment duration was 10 months. Most of IgG4-RD (n=34) were treated with prednisolone alone (47.4%) or combined with azathioprine (42.1%). They responded well to treatment, achieving partial remission (66.7%) or stable state (21.2%) of the disease. Nine patients had relapse and 1 patient died during follow-up. Conclusions: IgG4-RLD patients respond well to steroid and show favorable outcome, although some of them had relapse.

학교장의 서번트 리더십이 교사 직무열의에 미치는 영향에서긍정심리자본의 매개효과

박신희 인문사회 21 2022 인문사회 21 Vol.13 No.6

The Mediating Effect of Positive Psychological Capitalon the Influence of Principal’s Servant Leadershipon Teacher Job EngagementShinhee Park Abstract: The purpose of this study is to analyze the mediating effect of positive psychological capital on the effect of principal’s servant leadership on teacher’s job engagement. An online survey was conducted with 250 teachers working in middle schools in Daegu Metropolitan City, and frequency analysis, descriptive statistics, correlation and multiple regression analysis were applied using SPSS program. The effects of principal’s servant leadership and teacher’s positive psychological capital on job engagement and the mediating effects of principal’s servant leadership on teacher’s job engagement were analyzed. The principal’s servant leadership and teacher’s positive psychological capital were found to be predictors of teacher's job engagement, and the partial mediating effect of positive psychological capital was found to be significant in the effect of principal’s servant leadership on teacher’s job engagement. Therefore, in order for teachers to be immersed in their duties, it is necessary to find ways to strengthen the principal’s servant leadership and the teacher’s positive psychological capital. Key Words: Servant Leadership, Positive Psychological Capital, Job Engagement, Principal, Teacher 학교장의 서번트 리더십이 교사 직무열의에 미치는 영향에서긍정심리자본의 매개효과박 신 희* 연구 목적: 본 연구는 학교장의 서번트 리더십이 교사 직무열의에 미치는 영향에서 긍정심리자본의 매개효과를 분석하는데 목적을 두었다. 연구 방법: 광주광역시 중학교에 근무 중인 교사 250명을 연구 대상으로 온라인 설문조사를 수행하였고, SPSS 프로그램을 이용해 빈도분석, 기술통계, 상관관계 및 중다회귀분석을 적용하였다. 연구 내용: 학교장의 서번트 리더십과 교사 긍정심리자본이 직무열의에 미치는 영향, 학교장의 서번트 리더십이 교사 직무열의에 미치는 영향에서 긍정심리자본의 매개효과를 분석하였다. 결론 및 제언: 학교장의 서번트 리더십과 교사 긍정심리자본은 교사 직무열의를 예측하는 변인으로 나타났고, 학교장의 서번트 리더십이 교사 직무열의에 미치는 영향에서 긍정심리자본의 부분매개효과는 유의한 것으로 나타났다. 따라서 교사가 자신의 직무에 몰입할 수 있도록 학교장의 서번트 리더십과 교사의 긍정심리자본을 강화하는 방안을 강구해야 할 것이다. 핵심어: 서번트 리더십, 긍정심리자본, 직무열의, 학교장, 교사 □ 접수일: 2022년 11월 28일, 수정일: 2022년 12월 12일, 게재확정일: 2022년 12월 20일* 조선간호대학교 조교수(Professor, Chosun Nursing Univ., Email: joy7282@naver.com)

Acid-Catalyzed Rearrangements of Aldehydo Ozonides

박신희,허태성,Park, Sin Hui,Heo, Tae Seong Korean Chemical Society 2001 Bulletin of the Korean Chemical Society Vol.22 No.3

P-54 Comparison of QuantiFERON-TB Gold Plus with QuantiFERON-TB Gold-In-Tube in the diagnosis of tuberculosis infection

박신희,조경욱,심태선 대한결핵 및 호흡기학회 2017 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.124 No.-

Background: The interferon (IFN)-γ release assays (IGRAs) are widely used for the diagnosis of tuberculosis (TB) infection. Recently, an updated version test, QuantiFERON-TB Gold Plus (QFT-Plus), has been introduced which has additional antigen tube and stimulates both CD4+ and CD8+ lymphocytes. Methods: We conducted a prospective study to compare the results between QuantiFERON Gold-In-Tube (QFT-GIT) vs. QFT-Plus. Results: From March 2017 to September 2017, 98 subjects who had both test results were enrolled. Mean age was 47.9 years and 40.8% were male. Most (93.9%) of them had BCG vaccination and 8 patients were previously treated for TB. The reasons for IGRA testing were anticipated tumor necrosis factor (TNF) inhibitor user (42.9%), health care worker (HCW, 18.4%), abnormal chest radiograph (16.3%) and TB contact (13.3%). For QFT-GIT, 57 (58.2%) were positive and 1 had indeterminate result. For QFT-Plus, 47 (48.0%) were positive and 51 (52.0%) were negative. The results agreed between both tests in 81 patients (κ coefficient = 0.67). In 61 low-risk subjects (non-contacts), 44.2% and 37.8% were positive with QFT-GIT and QFT-Plus, respectively. In 31 high-risk groups (TB contact and HCWs), the positive rate was 80.6% and 58.1%, respectively. Among 6 active TB patients, 5 (83.3%) and 6 (100%) were positive, respectively. Discordant results were seen in 16 patients: 13 were QFT-GIT (+)/QFT-Plus (-) and the other 3 were QFT-GIT(-)/QFT-Plus (+). Conclusions: QTF-Plus showed moderate agreement with QFT-GIT in the diagnosis of TB infection.

F-11 Treatment outcomes of pulmonary pyrazinamide-resistant multidrug-resistant tuberculosis

박신희,조경욱,심태선 대한결핵 및 호흡기학회 2017 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.124 No.-

Background: Treatment outcome of MDR-TB has been improved recently with use of novel anti-TB agents such as bedaquiline and delamanid. However, it is unclear whether pyrazinamide-resistant (PZA-R), but simple (not pre-XDR/XDR-TB) MDR-TB requires novel drugs to improve treatment outcome. Methods: We conducted a retrospective comparison study to investigate the treatment outcomes of PZA-R or PZA-susceptible (PZA-S), simple MDR-TB. The patients treated with novel drugs were excluded. Results: Total 152 patients who had simple MDR-TB were included: 81 were PZA-R. Mean age was 40.8 and 45.1 years in PZA-R and PZA-S MDR-TB, respectively. The male sex was 65.4% and 60.6%, respectively. Other baseline characteristics were similar between two groups. The PZA-R were more resistant to ethambutol (50.0% vs. 36.6%, p=0.003). Regarding treatment, use of second-line drugs such as prothionamide and cycloserine were similar between groups (86.4% and 93.8% vs. 91.5% and 67%, p>0.05) but PAS was used more frequently in PZA-R (80.2% vs. 38.0%, p<0.001). Treatment duration was not different between two groups. Treatment success rate was 74.1% in PZA-R and 76.1% in PZA-S (p=0.852). Treatment failure was observed in 3 (3.7%) and 2 (2.8%) patients, respectively. The recurrence rate was similar; 3.7% (3/54) vs. 5.0% (2/54), respectively. Conclusions: The PZA-R, simple MDR-TB patients showed a comparable treatment success rate with that of PZA-S MDR-TB patients, even without novel drugs.