위험 음주자의 선별을 위한 한국어판 Alcohol Use Disorders Identification Test(AUDIT-K)의 최적 절단값

조근호(Keun-Ho Joe),채숙희(Suk-Hi Chai),박애란(Aeran Park),이해국(Hae-Kook Lee),신임희(Im-Hee Shin),민성호(Seong-Ho Min) 한국중독정신의학회 2009 중독정신의학 Vol.13 No.1

Objects:Through this study, we intended to set up new cut-off score for the screening of hazardous drinking using the Korean version of alcohol use disorders identification test (AU-DIT-K). Methods:A total of 1,100 subjects were enrolled in this study. Questionnaires about drinking patterns, AUDIT-K, CAGE and NAST (National Alcohol Screening test) were col-lected. The cut-off scores of AUDIT-K for hazardous drinking were calculated and determined by area under the Receiver Operating Characteristic (ROC) curve. Pearson’s correlation test was applied to validate the test and re-test data. Results:Suggestible cut-off scores based on drinking frequency and amount, the AUDIT-K for screening the hazardous drinking would be 11 for men and 8 for women. However, we further proposed the CAGE 1 point as a reference value and concluded that cut-off scores of 10 for men and 6 for women were more appropriate in screening of hazardous drinking in Korean subjects. According to these scores recommended limits for normal drink-ing behavior among Koreans would 13 standard drinks per week for men and 6 standard drinks per week for women. Conclusion:The lower cut-offs of 10 for men and 6 for women suggest that nationwide a more vigorous effort in screening for hazardous drinking is needed in order to prevent alcohol abuse and hazardous consequences.

일 산촌 지역의 음주 행태 변화- 6년 추적 조사 -

이유라(You-Ra Lee),신정호(Jong-Ho Shin),민성호(Seong-Ho Min),김태희(Tae-Hui Kim),김민혁(Min-Hyuck Kim),장형민(Hyung-Min Chang),박기창(Ki-Chang Park),안정숙(Joung-Sook Ah),전영안(Yong-An Jeon),장지숙(Jee-Sook Jang) 한국중독정신의학회 2005 중독정신의학 Vol.9 No.1

Objectives:This study was designed to find out the changes of alcohol use behavior and it’s attributing factors through two surveys conducted in 1998 and 2004 in a rural community. Methods:We selected 116 problem drinkers and 116 matched non-problem drinkers among 480 men of the first survey. We surveyed basic epidemiologic data and alcohol use behavior with several questionnaires. Results:The results were as follows : 1) Drinking amount and frequency decreased with increasing age. 2) More than half among previous problem drinkers did not show any significant change in their alcohol use behavior. 3) Most of previous non-problem drinkers maintained their past alcohol use behavior. 4) Continuous problem drinkers had larger amount of past alcohol drinking than no more problem drinkers. They had lower scores on awareness of negative consequence, higher scores on drinking for coping strategy of Alcohol Effects Questionnaire (AEQ) and higher scores on drinking urge to relieve hangover of the Severity of Alcohol Dependence Questionnaire (SADQ) than no more problem drinkers. 5) Continuous problem drinkers showed more smoking and earlier drinking than continuous non-problem drinkers. 6) Continuous problem drinkers became poorer than no more problem drinkers. Conclusions: Continuous problem drinking pattern was associated with larger amount of past alcohol drinking, higher drinking frequency, higher drinking urge to relieve hangover, higher use of drinking for coping strategy and less awareness of negative consequence.

중독 관련 행동 문제에 대한 일반인들의 인식조사

이소정(So-Jung Lee),윤해주(Hai-Joo Yoon),이태경(Tae-Kyung Lee),민성호(Seong-Ho Min) 한국중독정신의학회 2003 중독정신의학 Vol.7 No.1

The purpose of this survey was to obtain a comprehensive social attitude about alcohol, pathological gambling and internet addiction in a Korean city population. 425 volunteers living in Seoul were surveyed by questionnaire about the demographic data, attitude about behavioral problems related to addictions. They responded to these problems’severity about alcohol (82.1%), pathological gambling (75.3%), and internet (73%) addiction, But most of them answered that the perceived reason of alcoholism and internet addiction was social atmosphere (each 51.5%, 43.7%), and that the cause of pathological gambling was personality (38.2%). The rates of answer that chose the biological cause of addictions were 3.5% in alcoholism, 5.4% in pathological gambling, 3.6% in internet addiction. These results suggest that most of the people well recognized these addiction’s severity but they did not have a concept that addiction is a disease. Therefore, we concluded that to treat early, there should be systemic information and guidance about the clinical organizations or centers.

아동기 학업수행과 성인 정신질환의 연관성

권오인(Oh In Kwon),박기창(Ki Chang Park),신정호(Jong Ho Shin),안정숙(Joung Sook Ahn),민성호(Seong Ho Min),한준규(Joon Kyu Han) 한국정신병리진단분류학회 2000 精神病理學 Vol.9 No.1

N/A N/A

우울증을 동반한 진폐증 입원환자의 정신병리와 대처방식

박새한(Sae-Han Park),박기창(Ki-Chang Park),안정숙(Joung-Sook Ahn),한윤경(Yun-Kyoung Han),민성호(Seong-Ho Min) 대한사회정신의학회 2005 사회정신의학 Vol.10 No.2

연구목적: 장기간 요양 및 치료를 필요로 하는 진폐증 입원환자에서 우울증 유무에 따른 스트레스 대처방식 및 정신병리의 특성을 알아보 고자 하였다. 방 법: 태백시 소재 산재병원에 1개월 이상 입원중인 진폐증환자 85명을 대상으로 해밀턴 우울평가척도(HAM-D), 간이정신증상척도 (SCL-90-R), 상태-특성 불안척도(STAI), 대처방식척도(Ways of Coping Checklist)를 시행하였으며 대상자들을 해밀턴 우울평가척도(HAM-D)의 18점을 절단점으로 우울증 환자군과 대조군으로 분류해 사회 인구학적 특성, 재원기간, 대처방식의 특성및 정신병리 등을 비교하였다. 결 과: 연구대상 85명 중 22명(25.9%)이 해밀턴 우울평가척도에서 18점 이상으로 우울장애를 시사하였다. 우울증 환자군에서 문제 초점적 대처방식과 대처방식 총점이 낮았으며 나이가 많았고 교육정도가 낮았다. 진폐증 입원환자에게 나타나는 정신병리는 신체 화, 우울, 공포불안, 불안의 순서로 많았다. 결 론: 장기입원 진폐증환자에게는 우울증을 비롯한 정신병리가 많이 나타나는바 치료효율을 높이고 재활을 돕기 위해서는 정신증상을 조사하여 문제 초점적이며 적극적인 대처방식을 함양시키는 정신사회적 치료개입이 필요할 것이다. Objectives:We examined the presumptive association between psychological characteristics and coping style in hospitalized pneumoconiosis patients. Method:Eighty-five hospitalized pneumoconiosis patients were divided into two groups according to their Hamilton Depression Rating Scale(HAM-D) scores;Group A consisted of twenty-two patients with HAM-D score higher than 18, Group B had sixty-three patients with HAM-D score lower than 18. All of them were interviewed with the Hamilton Depression Rating Scale(HAM-D) and completed the Symptom Checklist-90 items-Revised(SCL-90-R), the StateTrait Anxiety Inventory(STAI) and Ways of Coping Checklist. Days of hospital care, socio-demographic data and three evaluation scores were compared between two groups . Results:Twenty-two patients’ HAM-D scores were higher than 18. Group A patients were older and their problem focused coping scores and educational levels were lower. Hospitalized pneumoconiosis patients showed somatization, depression, phobic anxiety and anxiety, in order. Conclusion:In our study, pneumoconiosis patients showed depressive symptoms and inadequate coping strategies.

우리나라에서 직업군에 따른 자살의 표준화사망비와 연령보정 비례사망비의 추세

윤진하(Jin-Ha Yoon),이기현(Ki-Hyun Lee),한규연(Kyu-Yeon Hahn),오성수,장세진(Sei Jin Chang),차봉석(Bong Suk Cha),민성호(Seong Ho Min),이경숙(Kyung Suk Lee),채혜선(Hye-Seon Chae),엄애용(Aeyong Eom),고상백(Sang Baek Koh) 대한직업환경의학회 2011 대한직업환경의학회지 Vol.23 No.2

서울시 강남정신보건센터의 운영과 문제제기

이주훈,민성호 용인정신의학연구소 1995 용인정신의학보 Vol.2 No.2

정신분열병 환자에서 지연성 운동장애와 양성, 음성 증후군과의 관련성

민성호,조두영,유범희 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.6

Object : The authors investigated the association between tardive dyskinesia and positive and negative syndrome in schizophrenia. Method : Eighty-two inpatients who satisfied DSM-Ⅲ-R criteria for schizophrenia and were given antipsychotic medication for more than two years were rated for positive and negative syndromes with the Postive and Negative Syndromc Scale(PANSS) as well as cognitive state with the Mini-Mental State Examination(MMSE). The subjects comprised 41 patients meeting Schooler & Kane's criteria for tardive dyskinesia and 41 age- & gender-matched control patients without tardive dyskinesia. Results : Statistically significant associations were found between tardive dyskinesia and negative syndrome, especially in female schizophrenic patients, bur there was no association between tardive dyskinesia and cognitive impairment. Patients with negative syndrome had a lower score in MMSE and a higher score in general psychopathology scale of PANSS with statistical significance than those with positive syndrome and intermediate type. Conclusion : Tardive dyskinesia was associated with negative syndrome in schizophrenia and it was suggested that there may be a sexual difference in the etiology of tardive dyskinesia and negative syndrome. Schizophrenics with negative syndrome had more severe cognitive impairment and psychopathology compared to those with positive syndrome or intermediate type, possibly due to their early onset and longer duration of illness.

항정신병약물 사용 중인 정신분열병 환자에서 올란자판으로의 교체 방법에 관한 연구(II) : Comparison of Safety 안전성 비교

안용민,권용실,권준수,민성호,박두병,양문정,소형석,송종호,신윤식,우행원,유범희,이홍석,정한용,한창환,김용식 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.5

연구목적: 이 다기관 공동임상연구는 사용 중인 항정신병약물을 ’직접 교체 방법’또는 ’시작-감량 교체 방법’중 한 가지 방법으로 올란자핀으로 교체한 후, 안정성 측면에서 두 교체 방법 간의 비교와 교체후의 변화를 관찰하기 위한 것이다. 방법: 국내 13개 병원의 입원 및 외래에 내원한 환자들 중 ICD-10 지단기준으로 정신분열병에 해당되며, 임상적으로 항정신병약물 교체가 필요한 환자를 대상으로 하였다. 두 가지 교체 방법 중 한 가지를 무작위로 피험자에 적용하였으며, ’직접 교체 방법’에 배정된 경우에는 사용중인 항정신병약물을 일시에 중단하고 10㎎의 올란자핀을 바로 투여하였고, ’시작-감량 교체 방법’에 배정된 경우는 10㎎의 올란자핀 투여하고 2주에 걸쳐서 기존 약물을 감량하여 중단하였다. 올란자핀 사용기간은 총 6주이며, 용량은 5∼20㎎ 범위로 제한하였다. 한정성 평가를 위해서 체중, 생명징후, 자발적인 이상반응 복, 실험실 검사 그리고 Simpson-Angus Scale(SAS), Barnes akathisia rating scale(BARS), Abnormal involuntary movement scale(AIMS). Liverpool University neuroleptic side effect rating scale(LUNSERS)등을 이용하였다. 결과: 총 103명의 정신분열병 환자를 대상으로 하였다. 사용한 올란자핀의 용량, 벤조디아제핀의 병용률, 탈락률과 탈락 사유, 자발적인 이상반응 보고, 생명징후, 실험실 검사 그리고 대부분의 부작용 척도 상에서 임상적으로 의미 있는 차이를 두 교체 방법간에 발견하지 못하였다. 다만 AIMS의 감소는 ’직접 교체 방법’군에서 보다 적었고, 항콜린제의 병용률은 ’시작-감량 교체 방법’군에서 보다 많았다. 기저 상태에서 전체 피험자의 SAS와 BARS 점수는 각각 3.5점과 1.8점이었으며 70% 이상의 피험자가 고프로락틴 혈증을 보였다. 올란자핀으로 교체한 후, SAS, BARS, AIMS 점수의 유의한 감소가 있었으며 고프로락틴 혈증을 보인 피험자 분율도 약 30%이하로 감소하였다. 그러나 교체 방법과 상관없이 올란자핀 교체 후 유의한 체중 증가가 있었다. 결론: 이 연구를 통해 교체 방법에 관계없이 비교적 안전하고 용이하게 올란자핀으로 교체 할 수 있음을 알 수 있었다. 그리고 기존 항정신병약물을 올란자핀으로 교체함으로써 일부 부작용들을 줄일 수 있음을 간접적으로 관찰할 수 있었다. 하지만 이 연구는 여러 제한점과 문제점을 지니고 있기 때문에 보다 체계적인 연구를 통해 검정이 필요하리라 생각된다. Objectives: This multicenter clinical trial involving 13 hospital sites compared the safely of switching to olanzapine between ’direct switching method’ and ’start-tapering switching method’. Method: This study included both inpatients and outpatients who fulfilled the criteria for schizophrenia as defined in the ICD-10, and were in need to be appropriate for switching antipsychotics. Subjects were randomly assigned to one of the two switching methods. For ’direct switching method’group, previous antipsychotics were abruptly discontinued and 10㎎ of olanzapine was administered, and previous antipsychotics was gradually tapered for 2 weeks. Olanzapine was used for 6 weeks and the dose was adjusted within the range of 5-20㎎. The safety of switching to olanzapine was measured with vital sings including body weight, adverse events reported spontaneously, laboratory tests, and various scales such as Simpson-Angus Scale(SAS), Barnes Akathisia Rating Scale(BARS). Abnormal Involuntary Movement Scale(AIMS), and Liverpool University Neuroleptic Side Effect Rating Scale(LUNSERS). Results: 103 patients were switched to olanzapine in this study. The comparison between two switching methods did not show any significant difference in the dosage of olanzapine used, the concomitant use of benzodiazepine, the rate and reasons of drop-out, the adverse events, vital signs, laboratory tests, and most scales for measuring side-effects. However, the decrease in AIMS scores was significantly lower in ’direct switching method’ group, and the concomitant use of anticholinergics was comparatively greater in ’start-tapering switching method’ group. At baseline, SAS and BARS scores were 3.5 and 1.8 points respectively, and more than 70% of the subjects showed hyperprolactinemia. After switching to olanzapine, SAS, BARS, and AIMS scores were significantly decreased and the proportion of the patients with hyperprolactinemia was also decreased to less than 30%. However significant weight gain after the treatment of olanzapine was observed regardless of switching method. Conclusion: This study may suggest that switching to olanzapine can be done with relatively high safety regardless of switching methods and olanzapine can significantly decrease some side-effects induced by other antipsychotics.