카드뮴 급성폭로에 의한 Metallothionein 생성과 독성작용

민경준,박정덕,홍연표,장임원,Min, Kyung-Joon,Park, Jung-Duck,Hong, Yeon-Pyo,Chang, Im-Won 대한예방의학회 1993 Journal of Preventive Medicine and Public Health Vol.26 No.2

Thirty five male Sprague-Dawley rats were treated with cadmium chloride solution ranging from 0.2 to 3.2mg $CdCl_2/kg$ by intravenous single injection. At 48 hours after administration of cadmium, total cadmium, MT bound cadmium and histopathologic finding in liver, kidney, lung, heart, testis, metallothionein in liver, kidney and total cadmium in bleed were examined. Tissue cadmium concentration was highest in liver, followed by in kidney, heart, lung and testis. Cadmium bound to rnetallothionein (MT-Cd) and ratio of MT-Cd to total cadmium were increased in liver and kidney dependently of cadmium exposure dose, but not significantly changed in other organs. On histopathologic finding, the most susceptible organ was heart in considering cadmium exposed dose, but testis in considering cadmium concentration. Blood cadmium concentration was increased with dose-dependent pattern, and significantly correlated with tissue cadmium concentration, so that we may estimate tissue cadmium concentration by measurement of blood cadmium concentration. Metallothionein in liver and kidney was increased with dose-dependent pattern, higher in liver than in kidney, and was significantly correlated with tissue cadmium concentration. However, metallothionein induction efficiency of tissue cadmium(${\mu}g\;MT/{\mu}g\;Cd$) was eater in liver than in kidney, and reverse to tissue concentration or exposed dose of cadmium.

우울증 치료에서의 어려운 문제들

민경준,Min, Kyung-Joon 대한생물정신의학회 2001 생물정신의학 Vol.8 No.1

Whenever a clinician manages the patients with depression, he may meet various problems that make it difficult to treat them. Even though he has good skills and knowledge about depression, some barriers will be appear during his practice. In general, the difficulties in treating depression are treatment-resistance, adverse effects of antidepressants, pregnancy in female patients, comorbid medical conditions, poor compliance, drug-drug interactions, and so on, which are related with pharmacological treatments. Here, only the two of them, the treatment-resistant depression and difficult problems concerned with pregnancy, were discussed. Some level of treatment resistance is the norm rather than the exception. As the treatment failure stems from inadequate treatment, it is important that the clinician should prescribe medications with sufficient doseage and adequate duration. And to overcome the treatment resistant depression the polypharmacy is necessary, in that case, the side effects and toxicities should be explored and managed immediately. So the clinician have to learn more about the pharmacokinetic and pharmacodynamic mechanisms of each drugs used in treatment of depression. When the risk of the fetus by the exposure is higher than the risk of untreated maternal psychiatric disorder, psychotropic medications should be used during pregnancy. Women who are maintained on psychotropics and become pregnant, as well as women with the new onset of psychiatric symptoms during pregnancy, should be carefully reassessed. However, data concerning the potential risk of long-term behavioral changes following prenatal exposure to psychotropics is rare, so further longitudinal follow-up studies are needed.

지리정보시스템과 빅데이터 분석 시스템을 활용한 관광 정책수립 방안 -인천광역시 주요 관광지 중심으로-

민경준,임희석,Min, Kyoungjun,Lim, Heuiseok 한국융합학회 2021 한국융합학회논문지 Vol.12 No.8

본 연구는 지리정보시스템과 빅데이터 분석 시스템을 활용하여 관광객 유입동향 및 소비패턴 분석에 목적을 둔 연구이다. 인천광역시 주요 관광지 중 송도센트럴파크와 차이나타운을 선정하여 2017년 6월 1개월 동안 유동인구 분석, 카드매출 분석을 진행하였다. 전국 광역시도로부터 송도센트럴파크에 방문한 관광객은 인천광역시, 경기도, 서울특별시 순으로 높게 나타났으며, 외국인 관광객 비중은 중국이 가장 높았다. 차이나타운 관광객의 카드 소비 이용건수는 남성이 여성보다 12.4% 높게 나타났고 카드소비 금액도 남성이 18% 높게 나타났다. 본 연구는 관광객들의 유입동향 및 소비패턴을 분석하여 관광정책 수립의 주요 쟁점들을 도출함으로써 관광정책의 전략적 방안을 제안하는데 시사점이 있다. 본 연구를 바탕으로 향후 관광 인프라 구축 개선에 도움이 될 수 있다고 기대된다. This study aims to analyze tourist inflow trends and consumption patterns using a geographic information system and big data analysis system. Songdo Central Park and Chinatown were selected among the major tourist destinations in Incheon, and floating population analysis and card sales analysis were conducted for one month in June 2017. The number of tourists visiting Songdo Central Park from metropolitan cities across the country was highest in the order of Incheon Metropolitan City, Gyeonggi-do, and Seoul Metropolitan City, and the proportion of foreign tourists was the highest in China. The number of card consumption used by Chinatown tourists was 12.4% higher for men than for women, and the amount of card consumption was also higher for men by 18%. This study has implications for proposing a strategic plan for tourism policy by analyzing the inflow trend and consumption pattern of tourists and deriving major issues in the establishment of tourism policy. Based on this study, it is expected that it can be helpful in improving the construction of tourism infrastructure in the future.

「만주국」 조선인의 ‘皇國臣民’觀

민경준(Min Kyongjoon) 부산경남사학회 2009 역사와 경계 Vol.72 No.-

This article focuses on the responses(separation and cooperation) of the Korenas in Manchuria to the concord of nations and oneness of Korea and Japan, as a part of research for investigating their identity. What did the Korenas in Manchuria who, on the whole, sympathized with oneness of Korea and Japan think of Japanes empire? How did they relate to Manchuria? This article gave attention to their own responses like this. This research can be summarized as follows. First, the Koreans in Manchuria came to be in discord with the concord of nations and oneness of Korea and Japan. Secondly, the movement of establishing the national organization composed of the Koreans alone by using the ideology of oneness of Korean and Japan came into existence while their position fell in the Manchuria Concord Association. Thirdly, the logic of pushing on their demand and profit to the last by insisting on oneness of Korea and Japan in the full scale mobilization system was developed.

오염 지수 산정법을 활용한 토양 내 중금속 오염도 평가

민경준(Kyungjun Min),홍영규(Youngkyu Hong),최원석(Wonsuk Choi),김의영(Euiyeong Kim),김성철(Sungchul Kim) 한국토양비료학회 2017 한국토양비료학회 학술발표회 초록집 Vol.2017 No.10

淸代 江南 해항 劉河鎭의 성쇠와 무역상인

민경준(Min Kyong-joon) 경성대학교 인문과학연구소 2008 인문학논총 Vol.13 No.1

이 글은 청대 江南 지방의 해항 市鎭의 하나인 劉河鎭의 성쇠 과정을 정리함으로써 교통기능 중심 市鎭의 기능과 발달상의 특정을 파악하고자 한 것이다. 江南 지방의 교통기능 중심 市鎭은 大運河를 비롯한 주요 수로변의 하항이나 연해의 해항 등 교통의 중추에 위치하면서 화물 집산지로서 발달해 왔다. 이들 市鎭 가운데 일부는 특정 상품의 생산으로도 유명하지만, 일부는 그렇지 못하다. 특히 후자는 정책적, 경제적 환경 변화에 부침이 심하다는 특정을 갖는다. 劉河鎭은후자의 유형에 속한다. 劉河鎭은 長江 하구 삼각주의 海港市鎭으로서 淸 전기에는 上海와 더불어 江南 지방의 해상 무역을 분담하면서 발달하였지만, 청 후기가 되면 지형적 변화와 함께 해항기능을 상실하고 쇠퇴하게 된다. 무역항으로서의 劉河鎭의 쇠퇴는 인근 上海의 번성과 궤를 같이 하고 있다. 그러나 종래의 연구에서는 淸代 전 시기를 통하여 上海의 해상무역만을 중시 했을 劉河鎭의 것은 관심 밖이었다. 근대의 대도시 上海 중심의 시각이 淸代 연구에도 영향을 끼친 것이다. 淸代 劉河鎭의 번성은 해항으로서의 입지조건과 기능 외에도 정부의 해운, 해양 정책을 배경으로, 북양무역을 주로 하여 이루어졌다. 그렇지만 교통 기능 일변도로 전개된 劉河鎭의 도시적 기능은 해항도시 이상으로는 발휘될 수 없었다. 무역은 배후의 대도시 蘇州에 의해 조종되었고, 무역이익은 劉河鎭에 재투자되지 않았다. 또한 산업적 기반은 취약하여 특산으로 내세울 상품은 거의 없었다. 淸代 후기 劉河鎭의 쇠퇴는 뻘의 퇴적에 의한 항구기능의 정지에 있지만 무역상인의 劉河鎭 탈출과 上海로의 이전, 그리고 上海의 번성에는 또 다른 이유가 있었던 것이다. This paper have examined the rise and fall of Liuhezhen(劉河鎭), seaport city in Jiangnan(江南), and its background. Liuhezhen is a seaport in Chang river(長江) Delta. While It had taken charge of seaborne trade with Shanghai (上海) in the early period of Qing, it lost the function of a seaport in the later period of Qing. The fall of Liuhezhen as trading port has the same way of the rise of Shanghai, its neighboring port. The existing studies laid a emphasis on only seaborne trade of Shanghai but were not concerned about Liuhezhen, because the view of Shanghai, a metropolis in the Modern Age had a influence on the valuation of Shanghai in the period of Qing. A market town(市鎭) as a transport center, which was located in a river port including the Grand Canal or a seaport, has been developed as a trading center. Some ports were famous for a local specialty, but others didn't. The latter ports had ups and downs according to changes of policy and geographical conditions. Liuhezhen belongs to the second type of port. The prosperity of Liuhezhen in the period of Qing was owing to a favorable situation as a seaport, and shipping and marine policy of the government. However, Liuhezhen wasn’t developed beyond a seaport, for its main function was a transport center. Its trade was put the wire by Suzhou(蘇州), a large city at the rear, and its profit was not reinvested in Liuhezhen. It also didn’t have well-known products. The fall of Liuhezhen in the later period of Qing was caused by suspension of functions as a port because of the expansion of foreshore. However, There were also above-mentioned reasons for traders of Liuhezhen to move into Shanghai.

청대 강남사선의 북양무역

민경준 ( Kyong Joon Min ) 명청사학회 2002 명청사연구 Vol.17 No.1

海禁政策被開放以後, 江南的北洋貿易是在分口收舶政策之影響下, 以劉河鎭爲中心進行的。貿易商人(海商)是以江蘇商人和山東商人爲主, 而海運業則江南沙船商, 特別是通州, 崇明商人勢力較强。 通過江南船的漂着資料可知, 江南沙船的主要海運狀況是; (一)乾隆末爲止, 比較遵守分口收舶, (二)安到達之地而言, 山東相對多于關東, (三)海運路則與嘉道時期的海運論者們所主張的觀点相反, 仍利用元朝至元19年和29年以來的沿岸海運路, (四)在航海日程方面也和海運論者所主張的旬日說、二旬說、一年三、四回往返說相反, 一般情況下, 一次航海需三十、四十餘日, 往返則需三、四個月, 因此一年二回以上是不大可能。 在江南沙船的海運經營方面, 開始出現擁有四十、五十소船商的現象是以借用船隻, 直接進行貿易或者運貨等船戶的存在爲前提的, 而船戶們的經營活動則在客商們給其提供船隻(雇船)下, 才有可能。漂着江南船的多半是客商作爲貨主而一起乘船, 這種現象可認爲是根据貨客要求而雇給的船隻, 而且在乾隆以後逐漸被變爲貨主不同船的托送等方式。 關于江南沙船的船載貨物方面, 進一步確認了北貨爲豆貨, 南貨爲棉布、棉花等多數主張, 但 到乾隆前期爲止, 通過海運供給江南的是山東豆貨而不是關東豆貨。而這一点又根据江海關稅收資料,; 至乾隆前期爲止, 占該關豆貨稅三分之二的是山東豆貨, 推定通關量平均爲84萬石, 又加算漏稅率則爲二百七十、八十萬石, 最多爲八百四十萬石, 而這與通過大運河, 只不구占四分之一, 由此可知, 海運論者所謂的關東豆貨一年爲千餘萬石等等認識是相當于反映嘉道時期的事情。

지방교육재정교부금법의 제·개정내용 및 법적 쟁점 분석

민경준 ( Min Kyong Jun ),이일용 ( Lee Il Yong ) 대한교육법학회 2017 敎育 法學 硏究 Vol.29 No.1

지방교육재정교부금법은 지방자치단체가 교육기관 및 교육행정기관을 설치·경영함에 필요한 재원을 교부하여 교육의 균형 있는 발전을 도모하기 위해 제정된 법이다. 1971년 의무교육 운영을 위해 제정된 이후 정책적·사회적 필요에 따라 총 30차례 개정이 이루어졌다. 그럼에도 불구하고 최근 지방교육재정교부금법에 대한 발의횟수는 꾸준히 증가하고 있으며, 이에 대한 쟁점 또한 다양화, 다각화가 이뤄지고 있다. 본 연구는 지난 40여 년간 지방교육재정교부금법의 제·개정과정과 법적 쟁점에 대하여 살펴보았다. 이를 통해 본 연구의 결과는 다음과 같이 정리할 수 있다. 첫째, 국가와 지방자치단체 간 갈등 해소를 위해 지방교육재정교부금의 부담 범위를 설정할 필요가 있다. 둘째, 학생 수 감소에 따른 지방교육재정교부금의 배분 전반에 대한 검토가 필요하다. 셋째, 지방자치단체와의 원활한 협조 방안을 강구해야 한다. 넷째, 특별교부금의 역할에 대한 정립이 필요하다. 최근 지방교육재정교부금법은 정책적 필요와 열악한 지방교육재정의 현실로 인해 개정에 대한 요구가 높다. 개정과정 속에서의 충분한 검토와 공청회 등을 통한 의견 수렴은 필수적이다. The purpose of the Local Education Finance Subsidy Act is to make a contribution to the balanced development of education by allowing the State to provide, in whole or in part, the financial resources which are necessary for the establishment and operation of educational institutions and educational administrative institutions. After established in 1971, there were 30 times amendment according to political and social needs. At first, the Local Education Finance Subsidy Act aimed to secure a budget to operate compulsory education in middle schools. But in recent years, those amendments tend to cover local budgets. In this study, we search the total process of the legislation and amendment of Local Education Finance Subsidy Act and it`s legal issues. By those studies, we can find these results. First, the burden range of local education finance subsidy should be set-up to solve the conflict between the central government and the local autonomous entity. Second, the review and adjustment of distribution of local education finance subsidy should be considered. Third, the good cooperation with local government should be devised. Fourth, the role of special subsidy should be redefined. Lately, the amendment of the Local Education Finance Subsidy Act is required, because of policy needs and poor local finance status. And review of amendment process, and acceptance of an opinion during public hearing will be inevitable.

청대 중국의 해삼 소비와 무역 - 동남아산을 중심으로 -

민경준(Min, Kyong-Joon) 효원사학회 2021 역사와 세계 Vol.- No.60

개항 전의 청 시기, 중국의 해산물 수입 특히 동남아로부터 수입하는 해삼의 양은 계속 증가하는 중이었다. 이 논문에서는 중국 내 해삼 소비 시장의 동향이 무역에 끼치는 영향을 파악하려고 한다. 기존의 적잖은 연구에도 불구하고 해삼 소비 시장의 구체적 모습은 뚜렷이 밝혀지지 않았다. 우리는 먼저 청대 중국인의 해삼 소비에 대한 인식과 관련하여 중국인이 선호하는 해삼을 중심으로 정리한다. 그리고 그와 같은 인식이 동남아에서 실제 수입하는 해삼의 양 및 품종과는 괴리되어 있다는 점을 부각한다. 그리고 그 괴리의 이유를 밝히기 위해 해삼요리의 조리법을 찾아내고 분석하는 순서로 논지를 전개한다. 청대 중국인들이 좋아하는 해삼은 『본초강목습유(本草綱目拾遺)』에서 말하는 ‘요삼(遼參)’과 ‘자삼(刺參)’이었다. 이들은 “요해(遼海)”에서 생산되거나 일본에서 수입하는 해삼을 말한다. 그러나 청 후기로 갈수록 중국에 수입되는 해삼 중에 ‘광삼(光參)’의 종류가 증가하였다. 이들은 원래 중국인이 선호하지 않던 해삼이다. ‘광삼’의 소비 증가는 동남아 해역의 해삼 수출을 지탱하는 주요한 요인으로 작용하였다. 그리고 그 배경에는 해삼을 삶고 고는 것에서 볶고 튀기는 것으로 조리법의 변화가 있었다. 동남아산 해삼의 소비 증가에 영향을 끼친 다른 이유를 밝히는 연구는 이후 더 진행될 예정이다. During the Qing period before the port was opened, the amount of seafood imported by China especially sea cucumber from Southeast Asia was on the rise. In this paper, we attempt to understand the impact of the sea cucumber consumption market trends on trade. Despite numerous existing studies, the specific shape of the sea cucumber consumption market was not clearly revealed. First, we summarize the types and characteristics of sea cucumbers preferred by the Qing Dynasty Chinese. In addition, it highlights the fact that such perception is different from the amount and variety of sea cucumbers actually imported from Southeast Asia. And in order to find out the reason for the disparity, it proceeds in the order of finding and analyzing a recipe for sea cucumber cuisine. The sea cucumbers that the Chinese people of the Qing Dynasty like are “Liaoshen(遼參)” and “Cishen(刺參)”, which are referred to in Bencaogangmushiwei(本草綱目拾遺). These are sea cucumbers produced in “Liaohai(遼海)” or imported from Japan. However, the type of “Guangshen(光參)” among sea cucumbers imported to China increases as it goes to the late Qing. This was originally a type of sea cucumber that the Chinese did not prefer. The increase in consumption of “Guangshen” acts as a major factor supporting sea cucumber exports in Southeast Asia. And the background of the increase in consumption of “Guangshen” is the spread of a recipe called “Hongxiao(紅燒)”. Further studies will be conducted later to reveal other reasons that have influenced the increase in consumption of sea cucumbers from Southeast Asia.

API X80 라인파이프 강의 인장 및 샤르피 충격 특성에 미치는 Mo 및 Nb의 영향

민경준 ( Kyung Zoon Min ),배진호 ( Jin Ho Bae ),김기수 ( Ki Soo Kim ),이도재 ( Doh Jae Lee ) 대한금속재료학회(구 대한금속학회) 2011 대한금속·재료학회지 Vol.49 No.10

In this study, three kinds of linepipe steels were processed by changing the amount of Mo and Nb to investigate the effects on microstructures, tensile and Charpy impact properties. All the specimens consisted of acicular ferrite, granular bainite and secondary phases such as martensite and austenite constituents (MA). The increase in Mo raised the volume fractions of the granular bainite and MA, and raised the number of fine precipitates, which increased the yield and tensile strengths and decreased the upper self energy and energy transition temperatures. In the steel having less Mo and more Nb, the volume fractions of the granular bainite and MA decreased, and a finer microstructure was observed. This microstructure suppressed the formation of separation during Charpy impact testing and led to a higher upper shelf energy and lower energy transition temperature, while the yield and tensile strengths were lower than those of the steels with more Mo and less Nb.