대학생의 기질 및 성격이 정신건강에 미치는 영향

노성현,채경선 한국효학회 2023 효학연구 Vol.- No.38

Background: According to Cloninger's personality model, factors in the temperament and character affect an individual's cognition, emotion, and behavior independently or through interaction between temperament and character. Through studies using the Temperament and Character Inventory(TCI-RS) developed based on Cloninger's theory, the relationship between temperament/character and psychopathology such as anxiety or depression has been confirmed. However, there is a lack of research to identify the relationship between temperament/character and non-pathological level of mental health experienced in daily life. If the relationship between temperament/character and mental health is identified, it will be possible to help discover and deal with potential risk factors for mental health through individual temperament and character traits. Purpose: The purpose of this study is to examine the affect of temperament and character factors on mental health and to verify the mediating effect of character in the affect of temperament on mental health. Methodology/Approach: The subjects of this study were 330 university students who were surveyed by temperament/character scale and mental health scale, and the effects of temperament/character on mental health and the mediating effects of character were verified using Baron & Kenny's three-step mediated regression analysis. Findings/Conclusions: First, factors that significantly affect mental health were identified as novelty seeking, harm avoidance, reward dependence, persistence, and self-directedness. Second, self-directedness showed a complete mediating effect in‘the relationship between novelty seeking and mental health’and ‘the relationship between persistence and mental health’, and a partial mediating effect in‘the relationship between harm avoidance and mental health’. Implications: This study is significant in that it identified the vulnerability of mental health through temperament and character traits and provided a basis for using self-directedness as a means of intervention in mental health problems.

Intracranial Hemangiopericytomas : A Retrospective Study of 15 Patients with a Special Review of Recurrence

노성현,Jae Joon Lim,조경기 대한신경외과학회 2015 Journal of Korean neurosurgical society Vol.58 No.3

Objectives : Although surgical resection is used to treat meningeal hemangiopericytoma (MHPC), there is a high risk of subsequent recurrence. This study investigated factors associated with treatment outcomes and recurrence in patients who had undergone surgical resection of intracranial MHPC. Methods : Fifteen patients underwent surgical treatments performed by one senior neurosurgeon between 1997 and 2013. Clinical data, radiologic images, surgical outcomes, recurrence, and other relevant characteristics were reviewed and analyzed. Results : Fifteen patients were included in the analysis, 12 (80%) of whom had tumors in the supratentorial region, and 3 (20%) of whom had tumors in the infratentorial region. Complete resection was achieved in all 15 patients, and 3 (20%) patients were administered radiosurgery and conventional radiotherapy after surgery as adjuvant radiotherapy. Three patients developed recurrence, 2 of whom had not received adjuvant radiotherapy. In 1 of the patients who had not received adjuvant radiotherapy, recurrence developed at the original tumor site, 81 months after surgery. The other 2 recurrences occurred at other sites, 78 and 41 months after surgery. The 5- and 10-year overall survival rates were 88.3%, while the 5- and 10-year recurrence-free survival rates were 83% and 52%, respectively. Additionally the mean Ki-67 index differed significantly between patients who did and did not develop recurrence (43% vs. 14%; p=0.001). Conclusion : Because of the high risk of MHPC recurrence, MHPC tumors should be completely resected, whenever feasible. However, even when complete resection is achieved, adjuvant radiotherapy might be necessary to prevent recurrence.

Changes in Trends of Spondylitis in Korea Based on a Nationwide Database

노성현,장호열,이상훈,최정규,진동규 연세대학교의과대학 2019 Yonsei medical journal Vol.60 No.5

The Effect of Denosumab and Risk Factors for Recurrence in Spinal Giant Cell Tumors: A Systematic Review and Meta-Analysis

노성현,하윤,조평구,김긍년,신동아,김상현 연세대학교의과대학 2022 Yonsei medical journal Vol.63 No.9

Purpose: Giant cell tumors (GCTs) are common benign primary bone tumors and are well known for their locally aggressive per-formance and tendency to recur. The purpose of this study was to analyze the effects of denosumab and risk factors for recurrentspinal GCTs. Materials and Methods: We searched PubMed, EMBASE, Web of Science, and Cochrane Library databases to identify differencesbetween individuals treated with and without denosumab and risk factors for spinal GCT recurrence. Patient data, including age,sex, tumor resection range, location, denosumab use, Campanacci grade, and radiotherapy, were documented. Comparable fac-tors were evaluated using odds ratios (ORs) and weighted mean differences (WMDs) with 95% confidence intervals (CIs). Results: Sixteen studies were included. The overall incidence of spinal GCT recurrence was 29%. Campanacci grade III tumorsshowed better recurrence outcomes than grades I and II (OR, 16.36; 95% CI, 4.19–63.93; p<0.001). Gross total resection (OR, 0.09;95% CI, 0.04–0.19; p<0.001), radiotherapy (OR, 0.27; 95% CI, 0.11–0.65; p=0.004), and the use of denosumab during subtotal resec-tion (OR, 2.95; 95% CI, 1.07–8.17; p=0.04) were important factors for reducing recurrence. Conclusion: Clinicians must consider the effects of gross total resection, radiotherapy use, and denosumab use in cases of subto-tal resection during spinal GCT treatment. So far, many researchers have used denosumab in spinal GCT, but none have clearlysuggested an endpoint. Most studies, however, recommend using it for more than 6 months.

Commentary on “Cervical Inclination Angle: Normative Values in an Adult Multiethnic Asymptomatic Population”

노성현,하윤 대한척추신경외과학회 2023 Neurospine Vol.20 No.1

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포탄의 꼬리날개가 기저항력에 미치는 영향에 대한 해석적 연구

노성현,김종록,방재원 한국군사과학기술학회 2019 한국군사과학기술학회지 Vol.22 No.5

Recently, research on projectiles with wings for precision guidance is actively underway. In this study, weanalyzed how the tail fins attached to the projectile affect the base drag. Aerodynamic analysis was performedwith RANS(Reynolds Averaged Navier-Stokes) equations using FLUENT, a commercial CFD(Computational FluidDynamics) code. Through the aerodynamic analysis, the base drag characteristics of the projectile by parameters(number, length, thickness, position, shape of tail fin) were investigated. The results of this study are expected tobe applicable to aerodynamic design of tail fins mounted on projectiles.

PE-GOX 연소가스 물성치를 적용한 핀틀 노즐 하이브리드 로켓의 수치해석 연구

노성현,허환일 한국항공우주학회 2015 한국항공우주학회 학술발표회 논문집 Vol.2015 No.4

핀틀추력기는 노즐 내부의 핀틀 구조물의 움직임을 통해 챔버압력을 변화시켜 추력을 조절할 수 있다. 본 연구에서는 PE(Poly Ethylene)와 기체산소를 사용하는 하이브리드 로켓의 연소가스 물성치를 적용하여 4개의 서로 다른 물성치와 핀틀 스트로크에 따른 핀틀 노즐의 수치해 석을 진행하였다. 특정 질량유량과 특정 O/F의 연소가스 물성치를 적용한 해석결과에서는 수직충격파 직후에 재순환 영역이 발생하는 것을 확인하였다. 핀틀 스트로크의 증가에 따른 유동해석 결과에서는 노즐목면적이 감소함에도 추력이 증가하지 않는 지점이 발생하였지만 대체적으로는 핀틀 스트로크의 증가에 따라서 추력이 증가하는 경향을 보였다. Pintle thruster can control thrust by chamber pressure variation through movement of a pintle structure in nozzle. Numerical analysis was performed by four different properties and pintle stroke by using combustion gas properties of PE(Poly Ethylene) and GOX(Gas Oxygen), simulating hybrid rocket combustion. Recirculation zone was generated right behind a normal shock wave when specific mass flow rate and specific O/F are used. Except some exceptional cases, thrust usually tended to rise by the pintle stroke.

Hoarseness after Section of a Cervical Vagus Nerve Schwannoma

노성현,장호열 대한말초신경학회 2017 The Nerve Vol.3 No.1

Schwannomas of the cervical vagus nerve are slow-growing asymptomatic solitary neck masses that rarely undergo malignant change. We report the case of a 41-year-old man who presented with a six-month history of a painless neck mass and paroxysmal coughing after palpation of the mass. Surgical excision of the mass was performed, and histopathological examination revealed that the mass was a schwannoma. The patient developed hoarseness after removal of the schwannoma, which originated from the fibers of the recurrent laryngeal nerve (RLN). We describe the relationship of the tumor and RLN and review the anatomy of the vagus nerve.

노인성 척추질환의 역학: 건강보험심사평가원 자료 기반 연구

노성현 대한의사협회 2021 대한의사협회지 Vol.64 No.3

According to the Statistics Korea in 2020, the elderly population aged 65 or older accounted for 15.7% of the total population, and by 2025 it will reach 20.3%, which will enter the super-aged society. In an aging society, many degenerative diseases occur with age. In particular, the spine is a structure that acts as a pillar of our body, and as we age, degenerative changes come. Representative senile spinal diseases include disc disease, spinal stenosis, spinal spondylolisthesis, scoliosis, kyphosis, and flat back syndrome. This study intends to examine the epidemiologic characteristics and trends of senile spinal diseases using Korean Health Insurance Review & Assessment Service database from 2010 to 2019. All of the senile spinal diseases have gradually increased in the number of patients and cost over the last 10 years. In addition, the proportion of those aged 60 and over increased among those diagnosed. And fusion surgery and discectomy also increased in the last 10 years, and the treatment cost and ratio of over 60 years old increased. Korea has already become an aging society. So, in the future, senile diseases will increase further, and among them, senile spinal diseases will steadily increase. As a result, the frequency and cost of surgery will continue to increase. Efforts are needed to understand this trend and to prevent senile spinal diseases. For example, regular exercise, proper posture and habits, adequate nutrition, and efforts such as quitting smoking should be required. When these efforts are made, more healthy old life will be achieved.

Predicting Mechanical Complications After Adult Spinal Deformity Operation Using a Machine Learning Based on Modified Global Alignment and Proportion Scoring With Body Mass Index and Bone Mineral Density

노성현,이혜선,박고은,하윤,박정윤,구성욱,진동규,김근수,조용은,김상현,김경현 대한척추신경외과학회 2023 Neurospine Vol.20 No.1

Objective: This study aimed to create an ideal machine learning model to predict mechanical complications in adult spinal deformity (ASD) surgery based on GAPB (modified global alignment and proportion scoring with body mass index and bone mineral density) factors. Methods: Between January 2009 and December 2018, 238 consecutive patients with ASD, who received at least 4-level fusions and were followed-up for ≥ 2 years, were included in the study. The data were stratified into training (n = 167, 70%) and test (n = 71, 30%) sets and input to machine learning algorithms, including logistic regression, random forest gradient boosting system, and deep neural network. Results: Body mass index, bone mineral density, the relative pelvic version score, the relative lumbar lordosis score, and the relative sagittal alignment score of the global alignment and proportion score were significantly different in the training and test sets (p < 0.05) between the complication and no complication groups. In the training set, the area under receiver operating characteristics (AUROCs) for logistic regression, gradient boosting, random forest, and deep neural network were 0.871 (0.817–0.925), 0.942 (0.911–0.974), 1.000 (1.000–1.000), and 0.947 (0.915–0.980), respectively, and the accuracies were 0.784 (0.722–0.847), 0.868 (0.817–0.920), 1.000 (1.000–1.000), and 0.856 (0.803–0.909), respectively. In the test set, the AUROCs were 0.785 (0.678–0.893), 0.808 (0.702–0.914), 0.810 (0.710–0.910), and 0.730 (0.610–0.850), respectively, and the accuracies were 0.732 (0.629–0.835), 0.718 (0.614–0.823), 0.732 (0.629–0.835), and 0.620 (0.507–0.733), respectively. The random forest achieved the best predictive performance on the training and test dataset. Conclusion: This study created a comprehensive model to predict mechanical complications after ASD surgery. The best prediction accuracy was 73.2% for predicting mechanical complications after ASD surgery. This information can be used to prevent mechanical complications during ASD surgery.