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RISS 인기검색어
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- 저자 : 김영관(Kim Young-Kwan) (검색결과 243 건)
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김영관,소양강,박다영,김현순,전재흥,추영국,고기성,Kim, Young-Kwan,So, Yang-Kang,Park, Da-Young,Kim, Hyun-Soon,Jeon, Jae-Heung,Choo, Young-Kug,Ko, Ki-Sung 한국식물생명공학회 2010 식물생명공학회지 Vol.37 No.3
Antibodies are powerful and versatile tools to play a critical role in the diagnosis and treatment of many diseases. Their application has been enhanced significantly with the advanced recombinant DNA and heterologonous expression technologies, allowing to produce immunotherapeutic proteins with improved biofunctional properties. However, with currently available technologies, mammalian cell-based therapeutic antibody production, as an alternative for production in humans and animals, is often not plentiful for passive immunotherapeutics in treatment of many diseases. Recently, plant expression systems for therapeutic antibodies have become well-established. Thus, plants have been considered to provide an attractive alternative production system for therapeutic antibodies, as plants have several advantages such as the lack of human pathogens, and low cost of upstream production and flexible scale-up of highly valuable recombinant glycoproteins. Recent advances in modification of posttranslational processing for human-like glycosylation in transgenic plants will make it possible that plant can become a suitable protein expression system over the animal cellbased current production system. This review will discuss recent advances in plant expression technology and issues for their application to therapeutic antibody production.
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시간영역 광 간섭 단층촬영 시스템의 소형 엔도스코프 제작 및 영상구현
김영관,이성헌,김용평,Kim, Young-Kwan,Lee, Sung-Hun,Kim, Yong-Pyung 한국광학회 2010 한국광학회지 Vol.21 No.5
We fabricated and characterized a compact endoscopic catheter for optical coherence tomography. The optical delay line (ODL), composed of a cylindrical piezoelectric transducer (PZT) and an optical fiber, was operated with a 1 kHz sinusoidal driving wave in the time-domain. When the ODL was driven with a sinusoidal wave function, the axial scanning speed was 6 m/s and the axial acquisition rate was 2000 line/s at a depth of about 3 mm. Endoscopic OCT images of a human finger and earhole were successfully obtained with an image rate of ten frames per second. 광 간섭 단층촬영 시스템(OCT)을 위한 소형의 광섬유 도관형 주사장치인 엔도스코프(endoscope catheter)를 제작하였다. 깊이방향 주사장치인 원통형 압전소자(PZT)를 이용한 광경로 지연기는 정현파 1 kHz로 구동하여 시간영역에서 엔도스코프 OCT 영상을 구현하였다. 정현파로 구동한 광경로 지연기의 속도는 6 m/s 이고, 깊이방향 스캐닝의 데이터 획득은 3 mm 기준에서 초당 2000 라인이다. 제작한 엔도스코프로 사람의 손가락 및 귀에 대한 초당 10프레임의 OCT 영상을 성공적으로 획득하였다.
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정현파로 구동되는 PZT 광경로 지연기를 이용한 광 간섭 단층촬영시스템
김영관,김용평,Kim, Young-Kwan,Kim, Yong-Pyung 한국광학회 2007 한국광학회지 Vol.18 No.4
We fabricated and characterized an optical delay line for optical coherence tomography (OCT). The delay line was composed of a cylindrical piezoelectric transduce (PZT) and a single mode optical fiber. The OCT system used a duplex scanning optical delay line which was symmetrically driven in the reference and sample arms. We showed that the sinusoidal-wave was superior to a triangular-wave for driving the optical delay line for scanning depth and repeatability. 광간섭 단층촬영(OCT)용으로 원통형 압전소자(PZT)와 단일모드 광섬유를 이용한 광경로 지연기를 제작하여 정현파로 구동하고 특성을 분석하였다. 제작한 OCT 시스템은 검침단과 기준단을 대칭 구동하는 이중 광경로 지연방식을 사용하였다. 정현파 구동을 통한 PZT 광경로 지연 방식은 삼각파 구동과 비교하여 입력파형의 첨두 부분에서의 비선형현상을 제거하여 높은 반복성을 나타냄을 보였고, 삼각파 구동으로는 불가능했던 부분을 영상화 할 수 있었다.
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광간섭 단층촬영(OCT)용 PZT 광경로 지연기에서의 편광모드 분산 및 열요동 보상
김영관,박성진,김용평,Kim, Young-Kwan,Park, Sung-Jin,Kim, Yong-Pyung 한국광학회 2005 한국광학회지 Vol.16 No.6
광간섭 단층촬영(OCT)용으로 원통형 압전소자(PZT)와 단일모드 광섬유를 이용한 광경로 지연기를 제작하여 그 특성을 분석하였다. 광경로 지연기에서 발생하는 편광모드 분산은 편광조절기로 조절하였고, 열요동을 2중 광경로 지연기를 구성하여 최소화하였다. 이중 광경로 지연기는 단일 광경로 지연기에 비해 2배의 측정 깊이와 속도를 구현하여 $18.6\pm0.5{\mu}m$의 해상도. 측정 깊이 1.68 mm, 측정 녹도 360.4 mm/s를 각각 얻었다. We have fabricated and characterized optical delay lines for optical coherence tomography, which is composed of cylindrical PZT(piezoelectric transducer) and single mode optical fiber. The polarization mode dispersion from the optical delay lines was compensated by the polarization controllers. By applying the duplex optical delay line, we minimized the thermal drift due to optical delay lines and obtained the scan range of 2 times that of a single optical delay line. The OCT system showed resolution of $18.6\pm0.5{\mu}m$, scanning range of 1.68mm, and scanning speed of 360.4mm/s.
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우세한 다리와 비우세한 다리 사이의 태권도 발차기 비교
김영관 ( Young Kwan Kim ),김윤혁 ( Yoon Hyuk Kim ) 한국운동역학회 2010 한국운동역학회지 Vol.20 No.2
The balanced performance of dominant and non-dominant leg is very important to Taekwondo sparring. The purpose of this study was to investigate whether elite Taekwondo athletes would have balanced biomechanical performance and intra-limb coordination in executing different types of Taekwondo kicks. Twelve athletes(more than 10 year practice experience) participated in this study and performed six basic kicks(i.e., the front, roundhouse, side, back, thrashing, and turning-back kick). Results indicated no statistical difference on response time, peak kicking velocity, single limb vertical jump height, and angle-angle plot between dominant leg and non-dominant leg(p>.05). In conclusion, elite Taekwondo athletes had equivalent ability between dominant leg and non-dominant leg in performing Taekwondo kicks. This might be an advantage to elite athletes for Taekwondo sparring because they could use both leg without any restriction.
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연구논문 : 유기 발광체의 에너지 준위 및 전자 상태 연구
김영관 ( Young Kwan Kim ),김영식 ( Young Sik Kim ),서지훈 ( Ji Hoon Seo ) 한국유화학회 2005 한국응용과학기술학회지 Vol.22 No.4
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