눈운동장애 없이 시력 저하를 보인 해면정맥동 내경동맥류 1예

김승훈,김선웅,김범태,장지호,Seung Hoon Kim,Sun Woong Kim,Bum-Tae Kim,Jee Ho Chang 대한안과학회 2012 대한안과학회지 Vol.53 No.3

Purpose: Oculomotor disturbance is the common manifestation of intracavernous carotid aneurysm cases. Intracavernous carotid aneurysms causing compressive optic neuropathy with no oculomotor disturbance are relatively rare due to their anatomical characteristics. We experienced a case of intracavernous carotid aneurysm which resulted in a shifted supraclinoid segment of the internal carotid artery, presenting with visual loss and visual field defect with no oculomotor disturbance. Case summary: A 40-year-old woman presented with loss of vision in the right eye. A relative afferent pupillary defect was observed in this eye. Visual field test showed quadranopsia in the right eye. Magnetic resonance imaging revealed that the intracavernous carotid aneurysm had shifted the supraclinoid segment of the internal carotid artery to the superomedial position. The right optic nerve was directly molded by the shifted supraclinoid segment of the internal carotid artery at the point of the bifurcation between the anterior cerebral artery and the middle cerebral artery. A Guglielmi detachable coil (GDC) embolization was performed successfully with no operational complications. Six months after coiling, best corrected visual acuity of the right eye was 1.0, and the visual field defect had recovered in all except the superior temporal field. Conclusions: Oculomotor disturbance is frequently associated with intracavernous carotid aneurysms. Nevertheless, optic neuropathy without oculomotor disturbance may be the only sign in patients with an intracavernous carotid aneurysm that causes shifting of the supraclinoid segment of the internal carotid artery. J Korean Ophthalmol Soc 2012;53(3):486-491

류마티스 관절염 환자에서 Conserved T 세포 수용체의 CDR3 motif를 표현하는 제2형 콜라겐 특이 T세포주의 형성과 유지

김승훈,조미라,윤지희,박성환,조철수,황수연,김호연,Kim, Seung-Hoon,Cho, Mi-La,Youn, Jeehee,Park, Sung-Hwan,Hwang, Sue-Yun,Cho, Chul-Soo,Kim, Ho-Youn 대한면역학회 2001 Immune Network Vol.1 No.1

Background: To determine the molecular structure of type II collagen-specific T-cell receptors associated with rheumatoid arthritis (RA). Methods: We generated CII-specific T-cell lines of 8 RA patients by prolonged in vitro culture with bovine CII (bCII) and the immunogenic peptide (256-270) of human CII. The proliferation response towards CII stimulation was measured from the uptake of 3H-thymidine. Changes in the secretion of Th 1 and Th2 cytokines in the culture supernatent were measured by ELISA. The TCR clonotypes of these T-cells were examined by RT-PCR/SSCP analyses of all 22 $V_{\beta}$ chains. Results: T-cells from patients' tissue exhibited strong proliferation index upon CII stimulation, which was maintained up to 6 months in the culture. The secretion of INF-$\gamma$from these T-cells increased along with the duration of culture time, while the amount of IL-4 production did not show significant changes. The SSCP band patterns of patients' T-cells appear as discrete bands unlike the smeary streak produced from normal samples. Some SSCP bands, each representing selected expansion of a TCR containing certain subtype of $V_{\beta}$ peptides, appeared to be identical in more than one patients. Among these, the expansion of SSCP band representing the $V_{\beta}$ 14 CDR3 region persisted after switching the antigen to the immunogenic human peptide (256-270). Conclusion: CII-reactive T-cells expressing distinct CDR3 motifs are selectively expanded in the peripheral blood and synovial fluid of RA patients, and their persistent proliferation upon CII stimulation, as well as the production Th 1-type cytokines, may play pivotal roles in RA pathogenesis.

$(HF)_2(CO)$ 분자착물에 관한 Ab Initio 연구

김승훈,Kim, Seung Hoon 대한화학회 1998 대한화학회지 Vol.42 No.6

$6-31+G^{\ast}^{\ast}와\;6-311+G^{\ast}^{\ast}$의 기본조를 사용해서 이합체 분자착물 FH…FH, FH…CO, FH…OC 뿐만 아니라 $(HF)_2(CO)$의 형성가능한 두가지 삼합체 분자착물들에 대해서 HF-SCF, MP2 그리고 B3LYP 계산을 수행했다. 이 삼합체 분자착물들에 대한 여러 가지 바닥상태 성질들을 구하였으며, 대응하는 단위체들과 이합체들의 성질들과 비교하였다. FH…CO가 FH…OC에 비해 평균 0.85 kcal/mol 만큼 안정했고, F-H…F-H…C≡O가 F-H…F-H…O≡C 보다 1∼2 kcal/mol 만큼 안정한 것으로 계산되었다. 삼합체 분자착물 형성에 따른 C≡O stretching band 는 그들의 이합체들(FH…CO, FH…OC)에 비해 각각 24, $37\;cm^{-1}$만큼, H-F stretching band는 각각 $54, 353\; cm^{-1}$만큼 red shift 되는 것으로 평가되었다. The HF-SCF, MP2 and B3LYP calculations have been performed on the two conceivable clusters $(HF)_2(CO)$ trimers as well as their dimer complexes FH…FH, FH…CO and FH…OC applying $6-31+G^{\ast}^{\ast}$, and $6-311+G^{\ast}^{\ast}$ basis sets. A variety of ground state properties of these trimer complexes have been listed, and compared with corresponding properties of isolated monomers and combined dimers. It was calculated that FH…CO is more stable than FH…OC by average 0.85 kcal/mol and F-H…F-H…C≡O is more stable than F-H…F-H…O≡C by 1-2 kcal/mol. The C≡O stretching bands of the F-H…F-H…C≡O and F-H…F-H…O≡C were red shifted by 24, $37\;cm^{-1}$ compared with the FH…CO and FH…OC respectively. Also, H-F stretching bands were red shifted by 54 and $353\;cm^{-1}$.

스펙트럼 영역 빛간섭단층촬영기를 이용한 근시 정도에 따른 황반 구조의 정량적 분석

김승훈,박주연,박태관,온영훈,Seung Hoon Kim,Joo Youn Park,Tae Kwann Park,Young-Hoon Ohn 대한안과학회 2011 대한안과학회지 Vol.52 No.11

Purpose: To investigate the correlation of macular retinal thickness and refractive error using spectral-domain optical coherence tomography (SD-OCT). Methods: A total of 120 eyes with no posterior abnormalities were enrolled in the present study. Subjects were divided into 3 groups based on their spherical equivalent. Visual acuity, refraction, slit lamp examination, tonometry and fundus examination were performed. Retinal thickness between the RPE and IS/OS junction was measured at the fovea, 1 mm (inner ring) and 2 mm (outer ring) superiorly, inferiorly, nasally and temporally using SD-OCT. Overall average thickness, average foveal thickness, and the inner and outer ring macular thickness were measured. Results: The average foveal thickness was significantly greater in the high myopic eyes than in the low to moderate myopic and emmetropic eyes (p = 0.001). However, the RPE-IS/OS junction thickness of the foveola and the outer macular thickness were significantly lower (p = 0.001, p = 0.002) in the high myopic eyes. There was a weak, but significant negative correlation between refractive error and average foveal thickness (r = -0.38, p = 0.001). A positive correlation was found between refractive error and the RPE-IS/OS junction thickness (r = 0.40, p = 0.001). Conclusions: Macular retinal thickness is related to refractive error in normal subjects. Effects of eyeball elongation are more apparent in high myopic eyes than in low to moderate myopic eyes. A significant decline in the RPE-IS/OS junction thickness suggests the photoreceptor outer segments in the foveola are damaged in high myopic eyes. J Korean Ophthalmol Soc 2011;52(11):1286-1295

마이크로파를 이용한 급속 가열 연신 공정의 동역학 모델링과 정상상태 특성 해석

김승훈,백영남,허유,Kim, Seung-Hoon,Paik, Yeong-Nam,Huh, You 한국섬유공학회 2006 한국섬유공학회지 Vol.43 No.6

Fiber forming is an important technology for producing multi-functional goods that have a flexible and structured plane form by using raw material with special properties. This research reports on the metal fiber manufacturing technology that adopted induction heating and drawing, but without use of dies that are now installed in the conventional wire drawing processes. Heating wires allows the drawing process to build up necking and to shorten the process by reducing the process steps so that a new and efficient production method of metal fibers is to be conceived and developed. A new device that can process a single wire consists of three major parts: the drawing part comprised of capstans, that is, feeding roll and take-up roll with specially hardened circumferential surface, the change gear part with continuously controllable draw ratio, and the heating part that includes a heating source and an energy propagation channel and an electromagnetic wave absorber With this device feasibility of the induction heating method is tested and the characteristics of the metal wire drawing process is analyzed. Results show that the microwave can be applied to attenuate the metal wire as a heating source and the experimental profiles of the cross-sectional area in the heated drawing zone under a steady state condition coincide well with those from theoretical model. The diametric variation of the drawn wires increased, however, as the drawing ratio increased.

정시안에서 스펙트럼영역 빛간섭단층촬영기를 이용한 연령과 성별에 따른 황반 두께의 변화

김승훈,최경식,이성진,Seung Hoon Kim,Kyung Seek Choi,Sung Jin Lee 대한안과학회 2011 대한안과학회지 Vol.52 No.3

Purpose: To evaluate the changes in macular thickness with regard to age and gender in normal subjects with emmetropia using spectral domain optical coherence tomography. Methods: The present study consisted of 90 healthy subjects (162 eyes) with no ophthalmic evidence of retinopathy and who had emmetropic eyes. The data from macular measurements using spectral domain optical coherence tomography was analyzed according to the groups divided by age (Group 1: 0 to 19 years of age, Group 2: 20 to 39 years of age, Group 3: 40 to 59 years of age, Group 4: 60 to 80 years of age) and gender. Results: Macular thickness of the central circle was 253.40 ± 23.03 μm in all subjects. There was no significant change with age (p > 0.05). However, the measurements at the inner (3 mm) and outer circle (6 mm) showed a reduction of macular thickness with age (p < 0.05). The macular thickness at the central and inner circle was significantly lower in the female subjects (p < 0.05). In group 3 and 4, macular thickness at the central circle in males was greater than in females. In group 3, the average inner macular thickness in males was significantly greater than in females (p < 0.05). Conclusions: In normal subjects with emmetropia, there are statistically significant differences in macular thickness between subjects of different age and gender. The results from the present study can be expected to provide a reference value for evaluating macular disease. J Korean Ophthalmol Soc 2011;52(3):299-307

PerFix<SUP>Ⓡ</SUP> Plug을 이용한 무긴장 탈장 교정술의 단기 성적 보고

김승훈(Seung Hoon Kim),정재희(Jae Hee Chung),송영택(Young Tack Song) 대한외과학회 2003 Annals of Surgical Treatment and Research Vol.64 No.5

2019년 자살 관련 지표들과 추이

김승훈 ( Seung Hoon Kim ),이두웅 ( Doo Woong Lee ),권준현 ( Junhyun Kwon ),양지은 ( Jieun Yang ),박은철 ( Eun-cheol Park ),장성인 ( Sung-in Jang ) 한국보건행정학회 2021 보건행정학회지 Vol.31 No.2

This study aimed to update suicide-related indicators including suicidal ideation, suicide attempts, and the number of suicidal deaths. Based on up-to-date information, we observed the trends of suicide-related indicators. In this study, five data sources were used to observe the trends of suicide-related indicators: Statistics Korea (1983-2019), Korean National Health and Nutrition Examination (KNHANES, ‘07-13, ‘15-19), Korean Community Health Survey (KCHS, ‘08-09, ‘13, ‘17), Korean Wealth Panel Study (KOWEPS, ‘12-19), and Korea Health Panel Survey (KHP, ‘10-13, ‘16-17). The suicide rate, which peaked in 2011, declined until 2017 and then started to rise again from 2018, recording a suicide rate of 26.9 per 100,000 people in 2019. The rate of suicidal ideation estimated based on the recently available data was 4.62% (KNHANES, ‘19), 3.51% (KHP, ‘16), 2.87% (KHP, ‘17), and 1.70% (KOWEPS, ‘19). That of suicide attempt as recent year was 0.43% (KNHANES, ‘19), 0.07% (KOWEPS, ‘19). Annual percentage change of death by intentional self-harm was -2.11% (Statistics Korea), and that of suicidal ideation was -14.7% (KNHANES), -2.5% (KCHS), -10.6% (KOWEPS), and -11.3% (KHP). Annual percentage change of suicide attempt was -5.0% (KNHANES), -4.4% (KCHS), and -11.3% (KOWEPS). The lower the income level, the higher the probability of experiencing suicide ideation and suicide attempts. Considering the recent increase in suicide rate in contrast to the continuing decline in suicidal ideation and suicide attempts, continuous data observation and appropriate policies regarding suicide prevention are needed.

사내근로복지기금이 성장성과 노동생산성에 미치는 영향 : KOSPI 200 제조기업

김승훈 ( Seung-hoon Kim ),윤병섭 ( Byung-seop Yoon ) 한국금융공학회 2020 금융공학연구 Vol.19 No.1

본 연구는 2002년부터 2018년까지 17년 동안 KOSPI 200 제조기업 159개를 대상으로 사내근로복지기금을 형성한 기업 87개와 사내근로복지기금을 형성하지 않은 기업 72개로 양분하여 사내근로복지기금이 성장성과 노동생산성 등 재무성과에 미치는 영향을 분석하였다. 실증분석 결과는 다음과 같다. 첫째, 사내근로복지기금을 형성한 기업이 고정효과에서 성장성인 매출액 증가율에 유의한 양(+)의 영향을 미치고 있음을 발견하였다. 둘째, 사내근로복지기금을 형성한 기업이 고정효과에서 노동생산성인 종업원 1인당 매출액 증가율에 유의한 양(+)의 영향을 미치고 있음을 발견하였다. 셋째, 사내근로복지기금을 형성한 기업이 고정효과에서 노동생산성인 종업원 1인당 부가가치생산성 증가율에 유의한 양(+)의 영향을 미치고 있음을 발견하였다. 넷째, 사내근로복지기금 기본자산 총액 변수, 경제성장률의 대용변수로 사용한 전년 대비 GDP 증가율 등이 매출액 증가율, 종업원 1인당 매출액 증가율, 종업원 1인당 부가가치생산성 증가율에 각각 체계적으로 유의한 양(+)의 영향을 미치고 있음을 발견하였다. 다섯째, 인건비 비율을 사내근로복지기금과 상호작용하였을 경우 매출액 증가율, 종업원 1인당 매출액 증가율, 종업원 1인당 부가가치생산성 증가율에 각각 체계적으로 유의한 양(+)의 영향을 미치고 있음을 발견하였다. 본 연구는 기금제도가 근로자의 근로의욕을 증진시켜 이직률을 낮추고 장기근속 유도로 숙련된 노동력이 불량률 감소, 원가절감 등으로 생산성을 높인다는 점을 시사한다. 즉 성장성, 노동생산성 등 재무성과가 향상되어 출연하는 기금액이 증가하는 선순환 구조를 이루므로 사내근로복지기금제도를 유용하게 활용할 필요성이 있다. This study analyzed the effects of the company labor welfare fund on financial performance, including growth and labor productivity, by dividing the total number of company work welfare funds into 87 companies that formed company work welfare funds and 72 companies that did not form company work welfare funds for 17 years from 2002 to 2018. The results of the empirical analysis are as follows. First, it was found that the comapnies that formed the company work welfare fund had a significant amount (+) effect on the growth rate of value added productivity per employee, which is labor productivity, in fixed effect. Second, it was found that the gross amount of the basic assets of the company work welfare fund and the year-on-year GDP growth rate used as a substitute for economic growth have systematically significant effects on sales growth, sales growth per employee and value added productivity growth per employee, respectively. Third, it was found that interaction of the labor cost ratio with the company work welfare fund affects systematically significant amounts (+) of increase in sales, increase in sales per employee, and increase in value added productivity per employee, respectively

가족복지를 위한 남북이산가족상봉

김승훈(Seung-Hoon Kim) 大韓赤十字社 人道法硏究所 2005 人道法論叢 Vol.- No.25

가족은 인류역사에 있어서 모든 제도 중 가장 끈질기고 강력한 제도로서 인간의 양육 및 성장과 함께 가족 구성원의 생물학적 생존과 재생산, 사회화 기능을 담당하고 있다. 복지국가를 지향하고 있는 우리나라에서는 ‘모든 국민은 인간다운 생활을 할 권리를 가진다’라고 헌법에 명시하고 있으며, 이것은 복지사회의 기초 단위인 가족의 행복을 위해서 이산가족문제를 해결하고자 하는 이유가 되는 것이다. 그러나 남과 북의 특수한 상황을 고려하여 볼 때 이러한 노력에는 일방적인 주장보다는 당위성과 법률적 근거가 있어야 한다. 이것은 크게 직접적 근거와 간접적 근거로 대별할 수 있는데, 직접적 근거에는 남북 사이의 화해와 불가침 및 교류 · 협력에 관한 합의서와 이에 대한 부속서가 있으며 간접적 근거에는 국제연합 헌장, 세계인권선언, 제네바협약, 7 · 4남북공동성명, 국제적십자회의의 결의, 휴전협정, 남북조절위원회 합의서 등이 있다. 이러한 여러 가지의 근거에도 불구하고 이에 대하여 의무적 이행을 강제할 수 없기 때문에 이산가족상봉의 어려움이 따르고 있는 것이다. 이에 본 연구는 이산가족의 상봉이나 교류 자체를 목적으로 보기 보다는 가족 기능의 회복을 향해 가는 과정으로 파악하였다. 남북이산가족이 서로 만나고 재결합을 이루거나 또는 재결합을 이루지 못한 채 가족의 회복 또는 가족의 정상화를 위해 나가는 과정에 국민적 관심이 증대되기를 바란다. 더욱이 이러한 국민적 관심속에서 이산가족의 고통을 경감하는데 우리 민족은 물론 국제적 공감대 형성과 북한 측의 성의 있는 자세를 다시 한번 촉구하는 바이다. Family, the most persistent and steadfast system among all systems existing in human history, is playing the roles of raising and developing humans as well as preserving, reproducing and socializing the family members. In Korea as a country pursing a welfare state, the Constitution declares that 'All people reserve the right to live a decent life.' This is why the problem of separated families must be solved for the happiness of families, which are the basic unit of welfare society. Considering the special situation of South and North Korea. however, such an effort must not be an one-sided insistence but be supported by sound legal grounds. Such grounds are largely divided into direct and indirect ones. Direct grounds include the Agreement on Reconciliation, Nonaggression, Exchange and Cooperation between South and North Korea and its annexed documents, and indirect ones include the United Nations Charter, Universal Declaration of Human Rights, the Geneva Conventions, 7/4 South-North Korea Joint Declaration, the Resolution of International Conference of the Red Cross and Red Crescent, the Armistice Agreement, the Agreement of the South-North Coordinating Committee, etc. Despite these grounds, however, the reunion of separated families cannot be forced as an obligation. Thus the present study understood the reunion of separated families or exchange between them as a process toward the restoration of the family functions rather than as a goal. It is necessary for people to take more interest in the process of restoring or normalizing families with or without the reunion of separated families in South and North Korea. Thus the author urges that, in addition to our efforts, there must be international consensus and North Korea's sincere attitude to reduce separated families' pains.