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배재형 ( Jae Hyung Bae ),조상래 ( Seong Eun Kim ),정은희 ( Sang Rae Jo ),장은희 ( Eun Hui Jeong ),김성은 ( Eun Hui Jang ),권희녕 ( Hui Nyeong Kwon ),박동엽 ( Dong Yeop Park ),이국천 ( Kuk Cheon Lee ) 한국가축위생학회 2010 韓國家畜衛生學會誌 Vol.33 No.2
Bovine brucellosis, an important zoonosis, is diagnosed with serological tests such as the RBT, TAT using inactivated whole bacterial cells or bacterial lipopolysaccharide (LPS) antigen in Korea. However, a strong cross-reaction between Brucella spp. and Yersinia enterocolitica O9 in these tests has seriously complicated the diagnosis of animal brucellosis because Brucella spp. shares common antigenic determinants with Y. enterocolitica O9 in the smooth LPS region. In this study, Brucella-field strains were isolated from Brucellapositive Hanwoo in Kimhae, Korea and outer membrane protein (omp) which has low cross-reaction with Y. enterocolitica O9 and high immunogenicity was extracted from the field strains Then we compared ELISA using the extract with RBT-TAT. Fifteen field strains were isolated from 47 supramammary-lymph nodes, which were collected from 18 farms. Isolation rate was 32%. Brucella-specific antigen was identified by performing SDS-PAGE or Western blotting on extracted omp with at 0.5% n-lauroylsarcosine One hundred and ninety-two serum-samples were used in the experiment: 142 negative and 50 positive samples verified by RBT-TAT. According to ELISA results, 127 samples were negative and 15 appeared positive among 142 negatives by RBT-TAT, while 42 samples were positive and 8 were negative among 50 positives by RBT-TAT. Therefore, it showed 89.4% of specificity and 84% of sensi-tivity. Through the current experiments, we could set up an ELISA based on the omp which has low cross-reaction and high immunogenicity and concluded that the omp could be a good material for accurate diagnosis of bovine brucellosis.
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건축공사 주요자재별 에너지소비량 및 CO<sub>2</sub> 배출 원단위 값 산출에 산업연관표 적용 적정성 검토 연구 -2005년, 2007년 산업연관표를 중심으로-
정영철,김성은,장영준,김태희,김광희,Jung, Young-Chul,Kim, Sung-Eun,Jang, Young-Jun,Kim, Tae-Hui,Kim, Gwang-Hee 한국건축시공학회 2011 한국건축시공학회지 Vol.11 No.3
한국은행에서 2000년도에 발행된 산업연관표를 적용한 주요 건축자재의 에너지소비량과 $CO_2$ 배출에 대한 원단위 DB는 있지만 2005년, 2007년에 발행된 산업연관표를 이용한 원단위 DB는 없는 실정이다. 본 연구에서는 최근에 발행된 2005년, 2007년도 산업연관표를 이용하여 주요 건축자재에서 발생되는 에너지소비량 및 $CO_2$ 배출 원단위 값을 산정하고자 한다. 주요 건축자재의 에너지소비량 및 $CO_2$ 배출원단위 산출을 위한 방법은 산업연관표를 이용한 DB 구축 방식을 바탕으로 산출하였으며, 건설현장에서 주로 사용되는 16가지의 건설자재는 선별하여 적용하였다. 기존 연구결과에서 제시한 2000년도 산업연관표를 적용하여 산출된 원단위 DB 값과 비교한 결과 근소한 차이를 보이고 있어 본 연구의 산출방법이 적정한 것으로 판단하였다. 2005년, 2007년도 산업연관표를 이용하여 산출한 에너지소비량과 $CO_2$ 배출 원단위 값은 감소세를 보이고 있는 것으로 나타났으며, 시멘트와 철근을 주원료로 하는 자재에서 가장 많은 에너지소비량 및 $CO_2$ 배출 원단위 값을 나타났다. 본 연구의 결과를 통해 국내 실정에 적합한 건설자재 생산단계에서 발생되는 환경부하의 간접적인 예측이 가능할 것으로 사료된다. Currently, there is database for per unit requirements of major construction materials in terms of energy consumption and $CO_2$ emission based on the input-output table published by the Bank of Korea in 2000, but no database for per unit requirements based on input-output tables was published in 2005 and 2007. The purpose of this study was to calculate the unit requirement values of major construction materials in terms of energy consumption and $CO_2$ emission generated by using the input-output tables published in 2005 and 2007. To estimate the unit requirement values, a database building method with the input-output tables was adopted by selecting 16 types of construction materials in wide use on construction sites. When the study results were compared with existing unit requirement values based on the input-output table of 2000, there were small discrepancies, from which it can be interpreted that the method used in the study is reasonable. Unit requirement values estimated based on input-output tables of 2005 and 2007 tended to decrease, and the highest value of energy consumption and $CO_2$ emission were found in the materials using cement and rebar.
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문대성 ( Dae Sung Moon ),장태원 ( Tae Won Jang ),옥철호 ( Chul Ho Oak ),정만홍 ( Maan Hong Jung ),유찬희 ( Chan Hui Yoo ),송준영 ( Jun Young Song ),김성은 ( Sung Eun Kim ),김자경 ( Ja Kyung Kim ),장리라 ( Lee La Jang ),이은영 ( Eu 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.63 No.5
Standard antituberculous therapy, including isoniazid (INH), rifampin, ethambutol, and pyrazinamide (PZA), is widely used to treat active tuberculosis. The most important side effect is hepatotoxicity. In a standard four-drug regimen, PZA was the most common cause of drug-induced hepatitis and was dose-related. The incidence of drug-induced hepatitis is high at doses of 40∼70 mg/kg per day but has fallen significantly since the recommended dose was reduced. Liver toxicity induced by PZA is rare at doses of 25 mg/kg per day or less. PZA-induced fulminant hepatic failure is also rare but fatal. We report a case of fulminant hepatic failure caused by a re-challenge of PZA. (Tuberc Respir Dis 2007;63:435-439)
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위 MALT 림프종에서 다발성 림프절 전이로 오인된 동시성 림프절 결핵 1예
김성은,김규종,김도현,송준영,문대성,장리라,유찬희,문원,박무인,박선자,김영옥 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2
28세 남자가 내시경적 점막절제술을 통해 저등급 위MALT 림프종으로 진단되었다. 병기설정을 위해 18F-FDG PET 검사를 시행하였고 우측 쇄골상부, 우측상/하부 기관주위, AP window 부위에 강한 섭취가 관찰되어 전이성 림프절로 판단하였다. 그러나, 우측 쇄골상부 림프절에서 시행한 절제생검에서 만성육아종성염증소견이 관찰되었고 조직의 결핵 중합효소연쇄반응에서도 양성 반응을 보였다. 2개월간 항결핵제의 사용 후 시행한 추적 컴퓨터단층촬영 검사에서 림프절 크기의 감소를 보여 최종적으로 위 MALT 림프종에서 광범위 림프절 전이로 오인된 동시성 림프절 결핵으로 진단되었다. A 28-year-old man was diagnosed as gastric MALT lymphoma in diagnostic EMR (endoscopic mucosal resection). He subsequently underwent an 18F-FDG PET. 18F-FDG PET showed intense multifocal uptake in right supraclavicular, right upper and lower paratracheal, and AP window areas that was considered radiologically to represent widespread metastatic lymphadenopathy. Excisional biopsy of a supraclavicular lymph node, however, revealed chronic granulomatous lymphadenitis with a positive reaction of Tb-nested PCR. After antituberculosis treatment for 2 months, a follow-up CT scan showed complete resolution of the lesions. Intense 18F-FDG uptake could be due to an infectious process such as synchronous tuberculous lymphadenitis. Therefore, this could mimic a malignant condition such as lymphoma with extensive lymph node metastasis due to a false-positive finding, which may lead to a misdiagnosis.
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