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다중박막적층법을 이용한 피톤치드 담지 Copoly(Styrene-Acrylic Acid)나노입자의 특성 제어
김민관,문성현,여지애,김한도 한국고분자학회 2024 폴리머 Vol.48 No.5
Mean particle size, colloidal stability, and release profile of copoly(styrene-acrylic acid) nanoparticles were controlled by layer-by-layer (LbL) assembly method using chitosan (CS) and carboxy methylcellulose (CMC) aqueous solutions. From FTIR analysis, successful layer assembly of CS and CMC was confirmed. Optimum conditions of LbL assembly was also confirmed by scanning electro microscopy (SEM) and particle size analyzer (PSA) analyses. Colloidal stability was evaluated by measuring zeta potential of particles. Release profile of core material (phytoncide oil) was measured by using UV-Vis spectrophotometer and high performance liquid chromatography (HPLC). (St-AA)NP prepared by miniemulsion copolymerization shows mean particle size and zeta potential of 351.0 nm and -39.77 mV, respectively. Mean particle size of LbL assembled particles can be controlled from 351 nm to 2,803 nm by optimization of LbL assembly conditions. Zeta potential values above ±40 mV evidence the coilloidal stability of particles. LbL assembled particles show controlled release profiles of phytoncide oil over 2 months.
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Native Aortic Valve Thrombosis Resembling Papillary Fibroelastoma
김민관,김석현,문상일,정유근,정의한,남화성,최재혁,박경일 한국심초음파학회 2014 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.22 No.3
The differential diagnosis of cardiac mass is important in determining the therapeutic plan and avoiding unnecessary surgical intervention. Non-invasive imaging methods would be useful in the diagnosis of suspected cardiac mass, because they may provideearlier diagnosis and more accurate assessment of cardiac mass. Native aortic valve thrombosis is a rare disorder and difficult todifferentiate from a tumor, and in particular, a papillary fibroelastoma. Thus, the clinical decision making with imaging modalitiesshould be performed cautiously. We recently met a female patient who had a aortic valve mass resembling papillary fibroelastomain normal native valve. The patient underwent a surgical resection and the pathologic finding showed an organized thrombuswith no evidence of papillary fibroelastoma.
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