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        간암환자에 있어서 Doppler 초음파 검사로 진단된 간내 동맥 - 문맥루

        강진경(Jin Kyung Kang),최흥재(Heung Jai Choi),김원호(Won Ho Kim),정재복(Jae Bock Chungj),안광진(Kwang Jin Ahn) 대한소화기학회 1988 대한소화기학회지 Vol.20 No.3

        Doppler ultrasonography, which provides noninvasive evaluation of bloodflow patterns has used widely in cardiovascular diseases. Recently intratumoral Doppler signal has been analysed to evalu- ate intra and peritumoral blood flow and to differentiate malignant from benign neoplasm. Hepatocellular carcinomas have characteristic vascular appearance including arteriovenous shunts that aid in their diagnosis and Doppler ultrasonography allows recognition of these arteriovenous shunts. But Doppler ultrasonographic observation of arterio-portal fistula involving relatively large branch of portal vein is very rare. We present a 55-year-o)d female patient with hepatoce)lular carcinoma showing characteristic L)oppler signal consistant with intrahepatic arterio-portal fistula which was confirmed by hepatic arteriography. After transarterial embolization with Gelfoam this high velocity flow signal was clisappeared.

      • SCOPUSKCI등재

        췌장의 유두상 낭성종양

        강진경(Jin Kyung Kang),최흥재(Heung Jai Choi),김원호(Won Ho Kim),홍성표(Sung Pyo Hong),노성훈(Sung Hun Noh),신동환(Dong Hwan Shin) 대한소화기학회 1988 대한소화기학회지 Vol.20 No.2

        Papillary cystic neoplasm of the pancreas is a rare low-grade malignant tumor which occurs chiefly in young women. It is also designated as a solid and papillary epithelial neoplasm of the pancreas because of its distinctive microscopic features, that is, papillary areas composed of layers of tall cells situated on fibrovascular stalks and solid areas consisting of sheets of cells with interspersed areas of cystic degeneration. Since the prognosis for this lesion is much more favorable than for any other pancreatic neoplasm due to its rare metastasis and recurrence rate, preoperative suspicion and correct diagnosis are important for this unusual and potentially curable tumor. We present a 22-year-old female patient with a papillary-cystic neoplasrn of the pancreas who complained of left upper quadrant abdominal pain. Ultrasonography demonstrated a large, partly cystic tumor in the pancreatic tail and abdominal cornputed tomography disclosed a well-defined solid and cystic mass. On celiac arteriography, the splenic artery and superior mensenteric artery were displaced by the tumor, and no tumor vessel was seen. ERCP showed displacement of the main pancreatic duct and absence of ductal branches in the mass area. The tumor was totally excised with the attached spl en and a small portion of the adherent distal pancreas on the 13th. Hospital day.

      • SCOPUSKCI등재

        식도 (食道) 편평유두종 (扁平乳頭腫) 2예

        강진경(Jin Kyung Kang),최흥재(Heung Jai Choi),박인서(In Suh Park),문영명(Young Myoung Moon),이상인(Sang In Lee),전재윤(Chae Yoon Chon),김원호(Won Ho Kim),박찬일(Chan Il Park),이강석(Kang Suk Lee),이광길(Kwang Kill Lee) 대한소화기학회 1984 대한소화기학회지 Vol.16 No.1

        Benign tumors of esophagus arising either from mucosa or submucosa are rare pathological entities. Of the benign esophageal tumor, squamous papilloma is a distinct rare pathological peculiarity recently reported with increased frequency, giving no symptoms during life and discovered unusually and in cidentally during autopsy. Morphologically, squamous papilloma of the esophagus was benign sessile lesions of surface epithelium characteristically composed of finger-like projections of tissue lined by increased numbers of squamous cells and having cores of fibrovascular tissue. Although the etiology of squamous papilloma of esophagus remains uncertain, the most convincing etiology of humans remains chronic irritation from gastric acid reflux. Squamous papilloma of the esophagus have not been shown to be premalignant. They should be removed completely so that coexisting malignant conditions are not overlooked. Recently we had the opportunity to observe two cases of histologically demonstrated squamous papilloma of the esophagus. Our purpose here is to report these patients and to review the literatures.

      • SCOPUSKCI등재

        간장 및 담도 : 생검으로 확진된 지방간의 임상적 고찰

        강진경(Jin Kyung Kang),최흥재(Heung Jae Choi),전재윤(Chae Yoon Chon),박찬일(Chan Il Park),윤정한(Jung Han Yoon),임대순(Dae Soon Yim) 대한소화기학회 1986 대한소화기학회지 Vol.18 No.1

        N/A Fatty liver is caused by derangement of fat metabolism and can be reversed by removal of contributing factors. The contributing factors of fatty liver include overweight, chronic alcoholism, diabetes mellitus, malnutrition, and drug abuse such as tetracycline. In this study, age and sex distribution, contributing factors, clinical features, liver function tests, correlation of grade of fatty liver to body weight, liver function test and viral markers were reviewed. Clinical diagnosis, peritoneoscopic diagnosis, and pathologic findings were compared in 54 cases with fatty liver proven by peritoneoscopic liver biopsy who were admitted to Yonsei University Severance Hospital from January 1981 to June 1985. The following results were obtained. 1) The mean age of 54 cases was 39. 9 years and the male to female ratio was 2.9 to 1 2) Contributing factors of fatty liver were overweight in 27 cases(50.0%), chronic alcoh- olism in 23 cases(42.5%), diabetes mellitus in 8 cases(14.9%), and malnutrition in 1 case (1 .9%). Overweight was the only contributing factor in 13 cases(24.o%), chronic alcoholism only in 12 cases(22.2%) There were more than one contributing factors in 16 cases(29.7%) and no definite contributing factors in 12 cases(22.2%). 3) Easy fatigability was the most frequent symptom which was found in 28 cases(52.7%) and hepatomegaly was the most common physical finding which was found in 26 cases (48.6%). 4) The r-GTP level was increased in 43 cases(80%), SGOT in 35 cases(65.5%), SGPT in 40 cases(74.5%), and triglyceride in 37 cases(68.9%). 5) The r-GTP and SGOT level were more elevated with statistical significance in chronic alcoholic group than in overweight group. G) There were no correlations of grade of fatty liver to body weight and liver function tests. 7) Eleven cases(22.5%) of 49 cases were HBsAg positive which was significantly higher than that of normal population in Korea. 8) A clinical diagnosis prior to peritoneoscopy was chronic hepatitis in 34 cases(62.8%), alcoholic liver disease in 9 cases(16.7%), fatty liver in 5 cases(9.2%), and HBsAg carrier in 4 cases(7.5%) A peritoneoscopic diagnosis was fatty liver in 3l cases(57.4%), chronic hepatitis in 10 cases(18.5%), acute unresolved hepatitis in 5 cases(9.3%), and normal liver in 8 cases(14.8%). In summary, the clinical diagnosis of fatty liver was made only in 5 cases(9.2%), and peritoneoscopic diagnosis of fatty liver in 31 cases(57.4%). The majority of the rest was chronic hepatitis. Therefore, it is mandatory to perform liver biopsy to distinguish fatty liver from chronic hepatitis.

      • KCI등재
      • SCOPUSKCI등재

        개에서 회장내 단백이 췌효소 및 담즙분비와 위배출 및 소장주행 시간에 미치는 영향

        강진경(Jin Kyung Kang),최흥재(Heung Jai Choi),박인서(In Suh Park),정재복(Jae Bock Chung),이상인(Sang In Lee),송시영(Si Young Song),정준표(Jun Pyo Chung),(Hiroshi Tohno),(eugene P . DiMagno) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.6

        N/A The aim of this study is to determine if protein in the ileum of dogs affects postprandial pancreaticobiliary secretion, gastric emptying, small bowel transit time, and circulating levels of gastrointestinal regulatory peptides such as peptide YY (PYY), neurotensin (NT), and pancreatic polypeptide (PP). Five dogs were prepared with permanent infusion and aspiration catheters in the duodenum and ileum. Ileal infusion (2 ml/rnin) was begun coincidentally with feeding a 300 Cal mixed nutrient meal containing both a iiquid marker (PEG 4000) and a solid marker (99mTc-sulfur colloid) in a conscious state of dogs. Ileal infusates were isosmolar solutions containing either 0.9% NaCl (control study) or 20 mg/rnl of protein solution (protein infusion study) in the 3:1 ratio of casein to essential amino acids. The secretory pattern of amylase and lipase was parallel, but. the secretion of trypsin was non-parallel to secretion of amylase and lipase. The pattern of exocrine pancreatic enzyme secretion was similar both in control and intraileal protein infusion studies. The secretion of exocrine pancreatic enzymes including amylase, lipase and trypsin, were increased by intraileal protein infusion compared with their secretion in control studies, and the secretion of amylase was significantly decreased (p<0.02) by intraileal protein infusion compared with their results in control studies. Although gastric emptying of both liquid and solid meals was delayed by the intraileal infusion compared with the control studies, there was no significant delay in gastric emptying (Tl/ 2) of liquid, whereas significant difference was noticed in gastric emptying (Tl/4) ol solid (p<0.02) between the control and intraileal protein infusion studies. The small bowel transit time was significantly prolonged (p<0.01) by intraileal protein infusion compared with time measured in control studies. The mean serum levels of PYY and NT were increased by intraileal protein infusion compared with those of control studies, but the mean serum level of PP was not changed. ln conclusion, it is suggested that intraileal protein riiay promote digestion and absorption of nutrients by increasing the enzyme secretion of the pancreas, delaying gastric emptying and prolonging small bowel transit time which may be influenced by hormones such as PYY and NT.

      • SCOPUSKCI등재

        위장관 ( 胃腸管 ) : 약년자 대장 및 직장암의 임상적 고찰

        강진경(Jin Kyung Kang),최흥재(Heung Jai Choi),박인서(In Suh Park),정재복(Jae Bock Chung),김원호(Won Ho Kim),김경희(Kyung Hee Kim),노성훈(Sung Hoon Noh),김도영(Doe Young Kim) 대한소화기학회 1991 대한소화기학회지 Vol.23 No.1

        N/A Colorectal carcinoma in young patients reportedly has a poor prognosis. Several reviews have suggested multiple explantations, including a low index of suspicion, delay in diagnosis or uniquely virulent tumor cells. However, some recent articles have suggested that the outlook is not necessarily dismal. To identify any distinctive characteristics of colorectal cancer in young patients, we studied the difference of incidence, initial symptoms, duration of symptoms, the location, gross types and size of the tumor, depth of invasion, resectability, lymph node involvement, distant metastasis, tumor stage by Astler-Coller classification, histologic types and five-year survival rates between 91 cases of young patients (less than 35 years of age) with colorectal cancer and 915 cases of eldly patients (35 years of age or more) as control, who were operated at Yonsei University Medical College, Severance Hospital during the 18 year period between January 1971 and December 1988. The results obtained are as follows: 1) The incidence of colorectal carcinoma in the young among total colorectal cancer patients was 9.0% (91/1,006 cases). There were 44 males and 47 females in the young age group, and the male to female ratrio was 0.93 : l. 2) There were no differences in the clinical symptoms, location, size, gross types of tumor and resectability between the two groups. 3) The duration of symptoms was longer in the younger age group than in the older age group. 4) The incidence of lymph node involvement was significantly higher in the younger age group than in the older age group (62.8% vs 39.2%; p<0.001). 5) The incidence of modified Dukes C cases was significantly higher in the younger age group than in the older age group (49.5% vs 33.49% p<0.001). 6) The incidence of mucinous carcinoma was significantly higher in the younger age group than in the older age group (32.5% vs. 10.1%; p<0.001). 7) The cumulative five-year survival rate was significantly lower in the younger age group than in the older age group (34.1% vs. 58.0%; p<0.005). 8) Even in the same stage or in the same status of lymph node involvement or with the same histologic type, the five-year survival rate was significantly lower in the younger age group than in the older age group. We conclude that the colorectal caricr in younger patients is worse than older patients. This unfavorable prognosis in young patients with colorectal cancer may be related to delayed diagnosis, more malignant histologic feature and other unidentified causes such as host factor. We suggest that a high degee of index of suspicion and aggressive treatment is mandatory even in young patients.

      • SCOPUSKCI등재

        한국인 간질환 (肝疾患) 환자의 B 형 간염 (肝炎) 바이러스 표식자 (標識子) 양성율에 (陽성율) 관한 연구

        강진경(Jin Kyung Kang),최흥재(Heung Jae Choi),박인서(In Suh Park),문영명(Young Myoung Moon),이상인(Sang In Lee),김영수(Young Soo Kim),박규숙(Kye Sook Park) 대한소화기학회 1983 대한소화기학회지 Vol.15 No.2

        N/A Authors carried out studies to determine the frequency of Hepatitis B virus markers in the serum of 3450 patients with liver diseases, who were diagnosed by clinically, biochemically, serologically and morphologically from September 1977 to August 1982 at Severance hospital, Yonsei University Medical College. The hepatitis B virus markers were measured by method of solid phase radioimmunoassay technique. The results obtained were summarized as follows. The positivity of HBsAg was 78. 9, in chronic active hepatitis, 68.4% in hepatoma, 60.1% in liver cirrhosis, 55.8% in chronic persistent hepatitis, 47.9% In chronic hepatitis, 45.7% in acute viral hepatitis, 37.9% in fulminant hepatitis. The overall positivity of patients with liver diseases was 54.6%. 2) The positivity of anti-HBs was 46.2% in fulminant hepatitis, 33.6% in chronic hepatitis, 27.0% in liver cirrhosis, 21.3% in hepatoma, 20.0% in chronic persistent hepatitis, 18.3% in acute viral hepatitis, 16.3% in chronic active hepatitis. 3) The positivity of anti-HBc was 100.0% in fulminant and chronic persistent hepatitis, 97.8% in chronic active hepatitis, 97. 6% in hepatoma, 88. 2%. In liver cirrhosis, 87% in chronic hepatitis, 74. 6% in acute viral hepatitis. 4) The positivity of HBeAg was 61.1% in chronic active hepatitis, 50.0% in fulminant hepatitis, 44. 6% in acute viral hepatitis, 38. 1% in chronic hepatitis, 37. 5% in chronic persistent hepatitis, 36.0% in liver cirrhosis, 20.2% in hepatoma. 5) The positivity of anti-Hbe was 66. 7% in fulminant hepatitis, 60. 0% in hepatoma, 48.0% in liver cirrhosis, 35.1% chronic active hepatitis, 33.3% in chronic persistent hepatitis, 29.4% in chronic hepatitis, 20.3% in acute viral hepatitis. 6) The detection rate of one or more markers among HBsAg, anti-HBs, anti-HBc in patients with liver diseases was 84.1%. And the most frequent distribution pattern of 5 hepatitis B viral markers was HBsAg(+), anti-HBc(+), anti-HBs( ), HBeAg(+), anti-HBe( ) in acute and chronic hepatitis, HBsAg(+), anti-HBc(+), anti-HBs( ), HBeAg( ), anti-HBe (+) in liver cirrhosis and hepatoma.

      • KCI등재후보

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