지상발표 : 간 형질세포종 1례

강진경,최흥재,김영수,전재윤,정남식 대한소화기학회 1979 대한소화기학회 추계학술대회 Vol.1979 No.-

북서태평양 표층대 박테리아와 바이러스의 공간 분포 특성

강진경,강선혜,이준,박지혜,황청연 한국수로학회 2022 한국수로학회지 Vol.11 No.2

Marine microbes, as essential members of lower trophic levels, play an important role in the biogeochemical cycle and cause impacts on the structure and function of marine ecosystems. To understand the spatial distribution of marine microbes in the Northwestern Pacific Ocean, the bacterial and viral abundances were measured for the epipelagic seawater samples (within 100 m), which were collected at 12 stations from the East Sea to the subarctic Bering Seaduring the R/V Aaron cruise in July 2012. Bacterial abundances were 0.2–1.9×106 cells ml-1 and gradually increased with increasing latitude. The variability of bacterial abundance was well explained by chlorophyll a concentrations rathern than physical variables. Cyanobacterial abundances were highest in the East Sea (1.8×105 cells ml-1) and were not detected in low temperature of seawater (8℃) above 55°N. Viral abundances were 0.8–15.2×106 viruses ml-1, and showed a significant positive correlation with bacterial abundances (r2=0.58, p<0.001, n=71). These results showed that the transfer of dissolved organic matter (DOM) from phytoplankton to higher trophic levels via bacteria (microbial loop) and the process of returning particulate organic matter (bacteria) to the DOM pool via viruses (viral shunt) in the study area. This study suggests that lower trophic level organisms are tightly coupled and contribute to the energy transfer and matter cycling in the marine ecosystem of the Northwestern Pacific Ocean.

내시경적 역행성 담췌관 조영술로 진단된 선천성 체관변이 9예

강진경,박인서,정재복,송시영,한기준,정준표 대한소화기내시경학회 1994 Clinical Endoscopy Vol.14 No.3

Although variation is the rule with pancreatic duct morphology, certain variants occur as a result of altered embroological development. These ductal configurations, most striking deviations from the normal configuration, may be classfied according to alterations of embryological development. These congenital variants of pancreatic duct may be important for several reasons. First, the pseudomass effect of ductal anomalies can be mistaken for carcinoma by the inexperienced radiologists. Second, whether or not the anomaly is important, it is present in many patients with recurrent pacreatitis. Original descriptions were based on small sampling of postmortem studies and surgical specimen, but more recently the advent of endoscopic retrograde cholangiopancreatography(ERCP) has confirmed of the work of early anastomists and increased awareness of these variants. To evalute of frequency, characteristics of associated disease and clinical significance of pancreatic anomalies, we have reviewed of 5330 case of ERCP filmes which were undertaken between July, 1973 and August, 1993. Having reviewed of ERCP filmes, we found out 9 case of pancreatic duct variants. Among them, 7 cases were classified as ductal duplication anomalies, 4 cases of number variation, most, bifuricaiton and 3 cases of form variation, which were composed of loop, spiral and terminal N. Three cases of fusion anomalies were also noted, which were 2 cases of panceratic divisum and 1 case of incomplete pancreatic divisum. The associated diseases were 6 cases of bile duct and galbladder stones and 3 cases of pancreatic cancer. We could not find out the case of congenital anomalies as cause of obstructive pain and pseudomass effect.

내시경적 역행성 담췌관 조영술후 발생하는 고아밀라제혈증의 병인에 산소유리기의 역할

강진경,서창희,박인서,문영명,함기백,정재복,이동기,문희용 대한소화기내시경학회 1994 Clinical Endoscopy Vol.14 No.1

There is growing evidence that oxygen-derived free radicals(OFR's) play a role in the pathogenesis of pancreatic diseases, especially of acute paetcreatitis. Many types of experimental ex vivo and in vitro pancreatitis can be inhibited by superoxide dismutase and catalse. Allopurinol also ameliorates the injury response. While these experiments strongly suggest the involvement of OFR's in some forms of experimental acute pancreatitis, their clinical significance is still unknown. Clinical trials with free radical scavengers or allopurinol are clearly needed to answer the question of free radical initiation of acute or chronic pancreatitis. The aim of this study was to know the role of OFR's on the ERCP-induced hyperamylasemia. Total forty-two patients who underwent ERCP for diagnostic purposes were included and randomly divided into two group6, non-pretreatment group(NP group 19 patients) and pretreatment group(P group, 23 patients pretreated with vitamin E 1000 I.U. and allpurinol 300 mg for 5 days before ERCP orally). 15 ml of venous bloods were drawn in EDTA treated tubes. Serial changes of serum amylase levels(U/ml), washed RBC malonyDdialdehyde levels(MDA, nmol/ml RBC), buffy coats myeloperoxidase activites(MPO, U/ml buffy coats), and plasma superoxide dismutase levels(SOD, U/ml) were measured before, 2 and 24 hours after ERCP, respectively. Serum amylase levels in P group were decreased than NP group, but without statistical significance. The mean RBC MDA levels of P group measuted 2 hr after FRCP were 3.43±1.13, which were significantly decreased than those of NP group(5.27±1.53)(p$lt;0.05). The plasma SOD levels of P group were 17.71 1.8, 20.41±1.3, 19.4±2.2 at before, 2 and 24 hr after FRCP, respectively, which were all significantly decreased than those of NP group(p$lt;0.05). The huffy coats MPO activities were not changed at all in spite of pretreatment. In conclusion, OFR's might be in volved in the pathogenesis of ERCP-induced hyperamylasemia, but do not play a major role. A protective effect of allopurinol and vitamin E could be expected.

영아교사의 정서지능과 소진의 관계에서 원장의 감성리더십의 조절효과

강진경,이진희 한국어린이미디어학회 2019 어린이미디어연구 Vol.18 No.3

The purpose of this study is to investigate the moderating effect of the director’s emotional leadership in the relationship between the emotional intelligence and the burnout of infant teachers. For this purpose, the questionnaires were applied to 245 teachers of day care center in J city, and emotional intelligence, exhaustion, and director’s emotional leadership were surveyed. The collected data were analyzed by correlation and regression using SPSS 24.0 statistical program. First, there was a positive correlation between the emotional intelligence of the infant teachers and the emotional leadership of the director. The relationship between the emotional intelligence and burnout of the infant teachers, and the relationship between the director’s emotional leadership and the burnout of the infant teachers appeared negative correlations. Second, there was a moderating effect of the emotional leadership of the director in the relationship between emotional intelligence and burnout of infant teachers. Through this study, it can be seen that the degree of burnout of the infant teachers can be buffered by the director’s emotional leadership. 본 연구의 목적은 영아교사의 정서지능과 소진의 관계에서 원장의 감성리더십의 조절효과를 알아보는 것이다. 이를 위해 J시 소재 어린이집 영아반 교사 245명을 대상으로 설문지를 활용하여 영아교사의 정서지능 및 소진, 원장의 감성리더십 조사를 실시하였다. 수집된 자료는 SPSS 24.0 통계 프로그램을 이용하여 상관분석 및 회귀분석을 실시하였다. 연구결과, 첫째, 영아교사의 정서지능과 원장의 감성리더십 간에는 정적상관이 나타났으며, 영아교사의 정서지능과 소진 간의 관계, 원장의 감성리더십과 영아교사의 소진 간의 관계에서는 부적상관이 나타났다. 둘째, 영아교사의 정서지능과 소진의 관계에서 원장의 감성리더십의 조절효과가 있는 것으로 나타났다. 본 연구는 원장의 감성리더십에 따라 영아교사의 소진정도를 완충시킬 수 있음을 확인하였다는 점에 그 의의가 있다.

생활습관병의 개념

강진경 대한의사협회 2004 대한의사협회지 Vol.47 No.3

담도계질환의 진단

강진경 한국의학사 1985 診斷과治療 Vol.5 No.1

총담관 결석 제거에서 풍선을 이용한 내시경적 유두부 성형술

강진경,박인서,문영명,정재복,이세준,이돈행,송시영,이천균 대한소화기내시경학회 1998 Clinical Endoscopy Vol.18 No.3

Background: The complications associated with endoscopic stone removal arise from the sphincterotomy that is performed to facilitate stone extraction. Early complications such as bleeding, perforation, pancreatitis and sepsis occur in about 10% of all patients. Moreover late complications may emerge due to the loss of the sphincter function. So the endoscopic removal of the bile duct stones without a sphincterotomy seems preferable in order to avoid the early complications related to the sphincterotomy, and may also help to preserve the function of the sphincter of Cddi. Aim: To evaluate the efficacy and safety of endoscopic balloon sphinteroplasty(EBS), we attempted to remove common bile duct stones, less than 12 mm, without sphincterotomy in 11 patients. We also investigated the effects of sphincteroplasy on the motility of sphincter of Oddi before and after EBS. Results: All patients were treated succesefully, with two patients administered sublingual nitroglycerine for the medical sphincter dilatation. Only one patient had mild abdominal pain, while the others experienced no complications. Follow-up manometric examinations showed the papillary function to be well preserved. Conclusion: This results suggested that the endoscopic balloon sphincteroplasy without sphincterotomy for the removal of small-sized stones is a useful and safe method, and its major advantage may lie in the preservation of the sphincter function. We recommend that prospective studies, preferably randomized, with clear objectives, are needed to clarify the success and safety of this technique compared to the standard sphincterotomy.

원발성 위 림프종의 내시경적 진단

강진경,박인서,문영명,정재복,이세준,양우익,박찬일,송시영,이명래 대한소화기내시경학회 1996 Clinical Endoscopy Vol.16 No.2

Primary gastric lymphorna represents one to 7% of all gastric cancer and is the most common type of extranodal lymphoma. In attempt to evaluate the endoscopic characteristics, we analysed clinical and endoscopic findings in 35 patients with primary gastric lymphoma between January 1980 and August 1994 at the Yonsei Medical Center. The results were as follows: 1) The mean age of patients was 47.1 years with male to female ratio of 1.5:1. 2) Gastroscopy was performed in all 35 patienits, which revealed polypoid lesion in one case(2.9%), ulcerative lesion in 15 cases(42.9%), ulcero-infiltrative lesion in 6 cases(17.1%) and diffuse infiltrative lesion in 2 cases(5.7%). Gastric lymphoma was suggested in 6 cases, advanced gastric cancer in 21 cases, early gastric cancer in 5 cases and benign gastric ulcer in 3 cases. Pathologic diagnosis of biopsy specimens were gastric lymphoma in 24 cases, adenocarcinoma in 5 cases and chronic superficial gastritis in one case. 3) The characteristics of the endoscopic findings in gastric lymphoma were intractable or recurrent ulcer in 10 cases, thickened and mounded ulcer margin in 9 cases, multiple ulcers in 9 cases, giant rugae in 7 cases and polypoid or depressed lesion with central ulceration in 4 cases. In conclusion, recognition of specific endoscopic findings such as intractable or recurrent ulcer, volcano-like ulcer, multiple ulcers, giant rugae and combined lesion, the possibility of a lymphoma should be considered and vigorous biopsy attempts should be carried out. Then if the first microscopic report does not suggest this diagnosis, a second investigation including jumbo biopsies, perhaps by diathermy, should be undertaken.

活動性 食道胃靜脈瘤出血의 內視鏡的 硬化治療에 關한 臨床的 考察

康鎭慶 고려대학교 의과대학 1986 고려대 의대 잡지 Vol.23 No.1

To evaluate the efficacy or impact of sclerotherapy in therapeutic regimen of bleeding esophageal varix, retrospective clinical analysis was made during period of 2 years from June of 1983 to June of at Hae Wha Hospital, Korea University Medical School. 71 cases with esophageal variceal bleeding were selected for clinical analysis. There were 63 cases(88.7%) of variceal bleeding due to liver cirrhosis, and 8 cases(11.3%) of hepatoma. Effectiveness of sclerotherapy was depended on anatomic site of bleeding and amount of transfusion. Lower and middle esophageal variceal bleeding were more effectively responded to sclerotherapy(100%), compared with cardiac and cardioesophageal junction 89.2% and 95.8% respectively. If total transfusion amount was over 10 pints, patients were less responded to sclerotherapy. Ethanolamine alone was the most effective and success rate was 100%, which was followed by ethanolamine with separately injected thrombin(91.7%), thrombin alone(89.7%) and thrombin and ethanolamine mixture(71.4%).