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윤희정 ( Hee Jung Yoon ),정준표 ( Jun Pyo Chung ),최승호 ( Seung Ho Choi ),김철식 ( Chul Sik Kim ),강병승 ( Byung Seung Kang ),이태희 ( Tae Hee Lee ),지상원 ( Sang Won Chi ),조준식 ( Jun Sik Cho ),문범수 ( Byoung Soo Moon ),이관식 대한소화기학회 2003 대한소화기학회지 Vol.41 No.2
Background/Aims: The purpose of this study was to evaluate the prognosis of gastric proper muscle (pm) cancer and its prognostic factors to identify a high risk group of patients with recurrence. Methods: Consecutive 154 patients (mean age, 57.6 years; M;
남문석(Moon Suk Nam),정준표(Jun Pyo Chung),이홍우(Hong Woo Lee),오제열(Je Yol Oh),박효진(Hyo Jin Pack),이관식(Kwan Sik Lee),이상인(Sang In Lee),박인서(In Suh Park),이안나(An Na Lee),송경순(Kyung Soon Song) 대한소화기학회 1994 대한소화기학회지 Vol.26 No.2
Behcets disease is a systemic disease involving skin, joint, gastrointestinal tract, vascular and nervous systems, characterized by recurrent oral and genital ulcerations and ocular in- flammation. The intestinal Behcets disease has nonspecific abdominal symptoms of colicky pain, constipation, diarrhea, nausea, vomiting, and malabsorption. Therefore, we need to dif- ferentiate with other diseases having nonspecific abdominal symptoms. We have experienced a case of lead intoxication after ingestion of herbal pills believed to contain lead compounds. A 40 year-old female with known Behcet's disaese was admitted due to acute colicky abdominal pain. The cause of abdominal pain and anemia was investigated and intestinal Behcets disease was ruled out. The diagnosis of lead intoxication was made by careful history, clinical manifestations, and various laboratory findings including peripheral blood smear, bone marrow aspiration and biopsy, serum lead and free erythrocyte protoporphyrin levels. W e also used lead mobilization test for measure of chelatable lead level. The treatment was performed with 4 courses of EDTA infusion therapy and the clinical symptoms and chemical data associated with lead intoxication improved.(Korean J Gastroen- terol 1994; 26: 399 404)
서정건(Jung Kun Seo),정준표(Jun Pyo Chung),조현근(Hyeon Geun Cho),이귀순(Kwi Soon Lee),이관식(Kwan Sik Lee),전재윤(Chae Yoon Chon),강진경(Jin Kyung Kang),박인서(In Suh Park),김기황(Ki Whang Kim),김호근(Ho Geun Kim),이상인(Sang In Lee 대한내과학회 1997 대한내과학회지 Vol.53 No.1
N/A We experienced a case of primary sclerosing cholangitis(PSC) in a 40-year-old female who complained of jaundice and pruritus. Marked elevation of serum alkaline phophatase level, typical beaded appearance and pruned-tree appearance on endoscopic retrograde cholangiography, together with a finding of chronic obliterative fibrosing cholangitis on sono-guided gun biopsy specimen of the liver led to a confirmative diagnosis of PSC. The patient responded to ursodeoxycholic acid (UDCA), but was reluctant to treatment and died of hepatic failure 7 months later. PSC is a very rare disease in Korea. So far, only 5 cases including our present case have been reported in the Korean literature. Male-to-female ratio was 2:3 and the median age was 40(27-80 years old). Ulcerative colitis was associated in one case. Four cases involved both intra, and extrahepatic bile ducts and one case was reported to be confined in the intrahepatic bile ducts. Fatality was in 3 cases, 20 days, 36 days, and 7 months after the initial presentaion, respectively. The causes of death were acute cholangitis and sepsis in two, and hepatic failure in one. We herein report a case of PSC and clinical charateristics of the reported cases in Korea, and review the literature with an emphasis on UDCA treatment in PSC.
이태희 ( Tae Hee Lee ),정준표 ( Jun Pyo Chung ),윤동섭 ( Dong Sup Yoon ),공지현 ( Jee Hyun Kong ),김수영 ( Soo Young Kim ),추적금 ( Juck Kum Chu ),최성우 ( Sung Woo Choi ),송시영 ( Si Young Song ),정재복 ( Jae Bock Chung ),이상인 대한소화기학회 2003 대한소화기학회지 Vol.41 No.2
Adenosquamous carcinoma of the pancreas is a rare but particularly virulent variant of invasive ductal carcinoma. In Korea, total 4 cases of adenosquamous carcinoma of the pancreas have been reported. Adenosquamous carcinoma of the pancreas has a slight m
김똘미(Dol Mi Kim),정준표(Jun Pyo Chung),박우일(Woo Il Park),박영년(Young Nyun Park),박승우(Seung Woo Park),이세준(Se Joon Lee),송시영(Si Young Song),이관식(Kwan Sik Lee),정재복(Jae Bock Chung),이상인(Sang In Lee),강진경(Jin Kyung Ka 대한소화기학회 2002 대한소화기학회지 Vol.39 No.2
Paragonimiasis is essentially a pulmonary disorder, but many organs such as the brain, muscle, mesentery, genital tract, spinal cord, spleen, and liver may be involved. Cases of hepatic paragonimiasis presented with hepatic masses have rarely been reported in Korea. We experienced a case of hepatic paragonimiasis incidentally found after a hepatic resection for treatment of localized left intrahepatic stones in an asymptomatic 51-year-old female patient. We report this interesting case of hepatic paragonimiasis accompanied with intrahepatic bile duct stones with a review of literature. (Korean J Gastroenterol 2002;39:133-136)
동결건조 갈색거저리 유충의 제조공정 표준화에 따른 자가규격 및 유통기한 설정
정미연 ( Mi Yeon Chung ),이정용 ( Jeong Yong Lee ),이진채 ( Jin Chae Lee ),박길수 ( Kil Su Park ),정준표 ( Jun Pyo Jeong ),황재삼 ( Jae Sam Hwang ),구태원 ( Tae Won Goo ),윤은영 ( Eun Young Yun ) 한국잠사학회 2014 한국잠사곤충학회지 Vol.52 No.1
본 연구에서는 갈색거저리 유충의 식품등록 후 산업화에 대비하여 대량생산 시설에 적용 가능한 동결건조 갈색거저리 유충곤충의 제조공정을 확립하였다. 갈색거저리 유충을 1 ~ 2일간 절식시킨 후 식용을 목적으로 하므로 위생적인 측면을 고려하여 분변제거 및 세척한 후 고온 · 고압 살균법으로 살균하였다. 살균시 용기 내에 부직포(48 cm × 55 cm)를 깔고 갈색거저리 투입량은 1 kg(3 cm)이하로 하는 것이 세균 및 진균의 제거에 효율적임을 확인하였다. 또한 생산효율을 증가시키기 위하여 다단식 살균기를 사용하여 각 단 사이의 공간을 10 cm 이상 확보하여 115oC, 1 kgf/cm2에서 10분간 고온 · 고압 살균한 경우 미생물이 검출되지 않음을 확인하였다. 살균한 갈색거저리 유충 동결건조를 위해 동결은 -35oC 이하에서 용기[W(63 cm) × L(57 cm) × H(3 cm)]별 4 kg씩(두께 1.5 cm 이하) 투입하여 실시하고, 건조는 -15oC 이하, 0.5 torr 이하에서 최소 30시간 이상 건조하는 것이 효율적인 것으로 판단하였다. 동결건조 갈색거저리 유충의 자가규격으로 수분 5% 이하, 산가 3 mg/g 이하, 과산화물가 30 meq/g 이하, 조단백 45% 이상, 조지방 25% 이상, 올레산 11 ~ 16%를 허용범위로 설정하였다. 마지막으로 이화학적 특성, 관능적 특성, 미생물학적 지표 조사를 통한 유통기한 설정 결과 PET 재질 용기로 포장될 경우 동결건조 갈색거저리 유충의 최종 유통기한은 제조일로부터 12개월로 결정하였다. 따라서 본 연구를 통해 확립된 대량생산 시설에 적용 가능한 동결건조 갈색거저리 유충의 제조공정을 통해 식품등록 후 산업화시 보다 위생적이며 균일한 제품 제조가 가능할 것이고, 자가규격 및 유통기한은 제품 관리에 응용되어 보다 안전성 및 안정성 확보가 가능할 것이라고 사료된다. This study was carried out to establish the self-specification and shelf-life by standardization of manufacturing process for Tenebrio molitor larvae. First, standardization of manufacturing process for T. molitor was set up. Sterilization for larvae placed on a multistage shelf with intervals of about 10 cm was carried out at 115oC, 1 kgf/cm2 for 10 min. After sterilization, T. molitor larvae were frozen at less than ?35oC for more than 12 hrs. And then, they were dried under ?15oC, 0.5 torr vacuum for more than 30 hrs. Second, we decided self-specification for T. molitor larvae. Their moisture, acidity, peroxide, crude protein and crude fat level should be 5% or less, 3 mg/g or less, 30 meq/g or less, 45% or more, and 25% or more, respectively. Also, oleic acid, representative material, level was set up 11 ~ 16%. Third, we decided shelf-life by analysis of the physicochemical characteristic, sensory evaluation and microbial indicators. The final expiry date for lyophilized T. molitor larvae in PET bottle was calculated as 12 months from date of manufacture. We expect that optimal manufacturing process system, self-specification, and shelf-life proposed in this study can be used in industrial production of T. molitor as a novel food.
급성 췌장염의 진단에 있어서 Urinary Trypsinogen-2 Dipstick 검사의 유용성
황성준 ( Seoung Joon Hwang ),정준표 ( Jun Pyo Chung ),김영균 ( Young Gyun Kim ),송대훈 ( Dae Hoon Song ),이재성 ( Jae Sung Lee ),백승석 ( Seung Seok Baek ),김도연 ( Do Yun Kim ),이덕용 ( Dok Yong Lee ),정연수 ( Yon Soo Jeong ) 대한소화기학회 2004 대한소화기학회지 Vol.43 No.6
Background/Aims: The clinical usefulness of urinary trypsinogen-2 dipstick test is still in controversy. We evaluated the usefulness of urinary trypsinogen-2 dipstick test in patients with acute pancreatitis. Methods: Urinary trypsinogen-2 dipstick test was prospectively performed in 50 patients with acute pancreatitis, 50 patients with non-pancreatic abdominal pain, and 50 healthy controls. Results: On admission, urinary trypsinogen-2 dipstick test was positive in 36 of 50 patients with acute pancreatitis (sensitivity, 72%) and in 4 of 50 patients with non-pancreatic abdominal pain (specificity, 92%). On the other hand, it was all negative in controls. The sensitivity and specificity of serum lipase were 78% and 94%, respectively. At 24 hours after admission, the positive rate of urinary trypsinogen-2 dipstick test rose from 72% to 94% (p=0.02). The results of urinary trypsinogen-2 dipstick test was positive in 14 of 15 patients with severe pancreatitis and 22 of 35 patients with mild pancreatitis according to the criteria by Atlanta International Symposium, 1992. Conclusions: Urinary trypsinogen-2 dipstick test is comparable to serum lipase in diagnosing acute pancreatitis. Delayed measurement and severe pancreatitis are more likely to yield positive results with urinary trypsinogen-2 dipstick test. Thus, we suggest that the cut-off value of urinary trypsinogen-2 dipstick test should be lowered to increase its sensitivity. (Korean J Gastro-enterol 2004;43:364-369)