요추 황색인대 및 후종인대 골화증 : 2례 보고

박승림,김형수,강준순,이우형,이주형,박주식 대한척추외과학회 1997 대한척추외과학회지 Vol.4 No.2

Ossifications of the ligamentum flavum(OLF) and the posterior longitudinal ligament(OPLL) are uncommon clinical entities as a cause of the progressive compression myelopathy or radiculopathy. Although there are considerable literatures concerning OPLL or OLF in cervical and thoracic spine, there are only a few references about OPLL or OLF in the lumbar spine. OLF and OPLL have been reported that they may lead to severe complication only with a minor trauma or even without trauma, such as paraplegia. The authors have experienced 2 cases of OLF accompanied by OPLL in the lumbar spine, who were treated with decompressive laminectomy and excision of ossified ligaments. For its rarity of OLF and OPLL in the lumbar region, we report here with review of literature.

Chitooligosaccharide가 생쥐의 간 기능에 미치는 영향

김세재,고영환,강소영,신태균,박승림 제주대학교 방사능이용연구소 1998 연구보고 Vol.12 No.-

Chitin의 탈아세틸화된 유도물인 chitosan과 chitooligosaccharides는 다양한 생리활성 기능을 나타내므로 생물 의학적인 응용에 많은 관심이 집중되고 있다. 본 연구는 수용성 chitooligosaccharide이 생쥐의 간 기능에 미치는 영향을 조사하기 위하여 수행되었다. 6주 동안 3% cholesterol를 식이한 생쥐에서는 혈장 cholesterol 함량이 증가하였으나, 1% chitooligosaccharide와 3% cholesterol을 함께 식이한 생쥐에서는 혈장 cholesterol 함량이 23% 정도 감소하였다. 그러나 혈장내 HDL-cholesterol과 간내 cholesterol 함량에는 유의한 차이가 없었다. 15% enthanol을 8주간 투여한 생쥐에서는 inflammation, necrosis, 지방구의 축적, GPT의 활성 증가등 간 상해가 관찰되었다. 그러나 0.5% chitooligosaccharide와 15% ethanol을 함께 투여한 생쥐에서는 ethanol에 의해 유발된 간 상해가 현저히 억제되어 지방구의 축적이 관찰되지 않았고, 혈장의 GPT 활성이 25% 정도 감소하였다. 따라서, chitooligosaccharide가 생쥐에서 혈장 cholesterol 함량을 감소시키고, 알코올성 지방간을 예방하는등 부분적인 기능이 있음을 보여주었다. Chitosan is the deacetylated product of chitin. Chitosan and its derivatives have many properties that make them attractive for a wide variety of health applications. This study was performed to investigate some effects of water soluble chitooligosaccharides on liver function in the mouse. The animals given the sterol diet containing 3% cholesterol for 6weeks showed increase in plasma cholesterol level, which were lowered by 23% when they were fed on 1% chotooligosaccharide. While there was no significant change in liver cholesterol and plasma HDL-cholesterol levels. Continuous administration of 15% ethanol via drinking water to mice for 8 weeks elicited pathological alterations such as inflammation, necrosis, accumulation of lipid droplets in the liver and increase in GPT activity, while simultaneous administration of ethanol and chitooligosaccharide prevented remarkedly ethand-induced liver injury; there was no observable lipid droplet and GPT activity was decreased by 25% in the liver. These results suggest that chitooligosaccharide play some roles in liver function, such as reducing the plasma cholesterol level and preventing alcoholic liver disease.

선천성 양측 전방십자인대 결핍

박승림,김형수,강준순,이우형,이주형,이동주,Park Seung Rim,Kim Hyoung Soo,Kang Joon Soon,Lee Woo Hyeong,Lee Joo Hyung,Lee Tong Joo 대한관절경학회 1997 대한관절경학회지 Vol.1 No.1

Congenital deficiency of the anterior cruciate ligament (ACL) is a rare disorder that has been reported in association with other knee dysplasia like as congenital knee dislocation. congenital short femur, congenital absence of menisci, congenital ring meniscus, and thrombocytopenia-absent radius syndrome. There has been no published explanation about the etiology of bilaeral ACL deficiencies without other abnomality. The patient of congenital ACL deficiency must be carefully inspected about combined anomaly. Those efforts may be helful in treatment or ACL deficient patients and evaluation of pathophysiology or ACL deficiency. However there has not been a ruptured congenital deficiency of the ACL without other dysplasia or the knee and other congenital skeletal abnomalities. We reported a case of symptomatic bilateral congenital deficiencies of the ACL which have not been associated with other skeletal abnormalities.

요추부 추간판 퇴행성 변화와 분절 불안정성 : 자기 공명 영상과 단순방사선 촬영 소견의 비교 A Comparison of Magnetic Resonance Images and Plain Radiographs

박승림,김형수,강준순,이우형,이주형,이동주 대한척추외과학회 1997 대한척추외과학회지 Vol.4 No.2

Summary of Literature Review : Many authors have described the association between lumbar disc degeneration and segmental instability but it has not been delineated in detail. Objectives : To compare the MRI assessment of disc degeneration with the conventional plain Xray evaluation of the intervertebral disc, in order to study lumbar segmental instability. Materials and Methods : In 75 patients with low back pain and/or sciatica, we analyzed disc space height, angular displacement, and horizontal displacement on plain radiographs of the lumbar spine. These parameters were compared with the grade of disc degeneration as evaluated by magnetic resonance imaging. Study Design : We analyzed the association between grade of disc degeneration as evaluated by magnetic resonance imaging assessment and segmental instability as evaluated by plain radiographs of the lumbar spine. Results : Disc space height was decreased in proportion to the grade of disc degeneration. Angular displacement was increased according to the grade of disc degeneration, but significantly less with severe degeneration, accompanied by a tendency to stabilization of the motion segment. Horizontal displacement was not correlated with the grade of disc degeneration. Conclusions : The incidence of lumbar segmental instability increased in proportion to the grade of disc degeneration but significantly decreased with severe disc degeneration.

선천성 종족골 단축에 대한 가골연장술

박승림,김명호,김형수,문경호,김영덕 최신의학사 1991 最新醫學 Vol.34 No.12

일측외고정장치를 이용하여 치료한 개방성 경골골절의 임상적 고찰

박승림,김형수,문경호,김이환 최신의학사 1994 最新醫學 Vol.37 No.1

둔부 구획 증후군 - 1예 보고 -

박승림,강준순,염승훈,고기홍,김형수 대한정형외과학회 2002 대한정형외과학회지 Vol.37 No.6

유구골 골절 및 탈구 : 치험 1례 One case report

박승림,김명호,김형수,문경호,최효엽 최신의학사 1992 最新醫學 Vol.35 No.1

장골의 외골종에서 속발한 연골육종 : 증례보고 A Case Report

박승림,강응식,한대용,장준섭 최신의학사 1974 最新醫學 Vol.17 No.10

This is a case, in a 27 year-old female, of secondary chondrosarcoma originating from a solitary exostosis of the central portion of the left iliac bone. Chief complaints were mild pain and a new hard growing mass which was just proximal to the left hip joint. Roentgenological study revealed a solitary exostosis with a pedicle which grew out from the cen?tral portion of the left ilium. Surgical en bloc excision in rectangular shape was performed, including the left iliac crest, under the clinical suspicion of chondrosarcoma since it had begun to grow with new activity after her growth cessation. Pathological diagnosis revealed an exostosis and there was no evidence of malignancy. With recurrence of the tumor, left hemipelvectomy was advised, under the clinical diagnosis of secondary chondrosarcoma, but the patient refused. Two other surgical excisions were performed and pathological diagnosis revealed secondary chondrosarcoma. A total of 6000 rad of radiation therapy was done. A pulmonary metastasis was noticed 4 months after the 3rd operation. Clinical findings were very important in the diagnosis of malignant change of the tumor.

γ-Poly(glutamic acid)와 키토산 공중합체 필름의 물성

박승림,고영환 제주대학교 생명과학연구소 2001 제주생명과학연구 Vol.4 No.-

Chitosan was prepared from crab shells. γ-Poly(glutamic acid)(y-PGA) was purified from culture filtrate of Bacillus licheniformis ATCC9945a. γ-PGA-chitosan interpolymers were used to make than films. Tensile strength, extent of elongation, weight loss in water, and moisture gain under standard conditions of the films were determined. Tensile strength of the γ-PGA-chitosan interpolymer film was 85.5MPa and its extent of elongation was 12.5%. When the interpolymer film was suspended in distilled water at 20℃ for 24 hours, the weight loss was 6.8%, which was much lower than those of γ-PGA film 100% or chitosan film 47.7%. Moisture gain of the interpolymer film showed the similar tendencies to the case of the weight loss and it was only 18.4% by weight under standard conditions.