신 이식후 거부반응 환자에서의 In Situ 교잡법을 이용한 Herpesviruses의 검출

심상인,김양리,강진한,유진홍,윤영석,강문원,박인석,방병기,신완식,최영진,장윤식 대한감염학회 1993 감염 Vol.25 No.4

Viral infection would have a deleterious impact on renal graft survival, and increase the morbidity and mortality in renal transplant patients. The clinical diagnosis of viral infection in renal transplant is difficult. Standard procedure for identification of viruses is tissue culture, but it takes much time. Serological diagnosis of viral infection does not always represent the clinically apparent infections. Recently, the value of direct virus detection by nonisotopic DNA probe in situ hybridization (ISH) has been introduced. To evaluate the potential role of cytomegalovirus(CMV), Epstein-Barr virus(EBV) and herpes simplex virus(HSV) on renal graft rejection, eleven rejected kidney allograft specimens were analyzed by ISH with biotinylated DNA probes. CMV-infected lung tissue, EBV-infected lymph node tissue and HSV-infected skin tissues were used as positive controls. One specimen showed positive hybridization with CMV probe and one with EBV probe. The whole procedure can be completed in less than 1.5 hours. In conclusion, we suggest the colorimetric method for ISH could be a powerful tool of detection of viruses in tissues without the need of radioactive probe. Cytomegalovirus, Epstein-Barr virus and herpes simplex virus may be of minor importance in triggering allograft rejection in Korea.

제주 4·3사건 초기 ‘무장대의 조직과 활동 - 「제주도인민유격대 투쟁보고서」의 분석

장윤식 제주4.3연구소 2005 4.3과 역사 Vol.5 No.-

연소합성법에 의한 $MoSi_2-Al_2O_3$ 복합재료의 특성에 미치는 $Mo/MoO_3$ 몰비의 영향

장윤식,이윤복,김용백,김인술,박흥채,오기동 한국세라믹학회 1996 한국세라믹학회지 Vol.33 No.11

MoSi2-Al2O3 composites were prepared by thermal explosion mode of self-propagating high temperature syn-thesis (SHS) using element powders of MoO3 Mo Si and Al. The combustion products of MoSi2 which have 10, 20, 30 and 40 wt% Al2O3 showed the molten state in the range of Mo to MoO3 6:1-9.5:1, 2:1-8:1, 1:1-5:1, and 1:1-3:1 (molar ratio) respectively. The combustion products which made least seperation the molten phase from the slag phase were in Mo/MoO3=9, 5:1, 8:1, 5:1 and 3:1 (molar ratio) respectively. Particles size of MoSi2 and Al2O3 in the combustion product were decreased as the molar ratio of Mo to MoO3 increase. By XRD analysis only MoSi2 and $\alpha$-Al2O3 peaks were identified in the combusion products, In case of MoSi2 containing 20wt% Al2O3 5.1wt% Al existed into MoSi2 grains and 30.7wt% Si and 7.7wt% Mo existed into Al2O3 grains. The relative density of MoSi2 containing 10, 20, 30 and 40 wt% Al2O3 were 82.7, 85.2, and 81.9% respectively. The fracture strength of MoSi2-Al2O3 composites increased with increasing Al2O3 and that of MoSi2-20wt% Al2O3 composite was 195 MPa.

연소합성법에 의한 Plasma-arc Deposit 용 $Cr_3C_2$ 합성 및 특성에 관한 연구

장윤식,윤정아,이윤복,박성수,김인술,박흥채,오기동 한국세라믹학회 1996 한국세라믹학회지 Vol.33 No.11

Using Cr2O3 Al and graphite powders as starting materials Cr3C2 was synthesized by combustion synthesis process according to the following reaction : 3Cr3C2 +4C+6Allongrightarrow2Cr3C2 +3Al2O3. The synthesis was conducted at 2 atm in an argon atmosphere. in this study main-product was monolithic phase of Cr3C2 /Cr7C3 mixture and sub-product was slag state of $\alpha$-Al2O3. Single phase of Cr3C2 was obtained when crushed main-product was heat-treated at 120$0^{\circ}C$ for 3h in vacuum state with addition of 2.5wt% C. The obtained Cr3C2 powder can be used as plasma-arc deposit material because the flowability index of powder with the size of 9-50${\mu}{\textrm}{m}$ was 66.

ASEA-SKF 래들용 내화재의 용손현상

박홍채,오기동,박성수,이윤복,장윤식 釜山大學校生産技術硏究所 1995 生産技術硏究所論文集 Vol.49 No.-

ASEA-SKF 래들에 사용된 마그카본, 마그크로 내화물의 광물 및 화학적 변화가 화학분석, 현미경 관찰, X-선 회절분석에 의해서 조사되었다. 마그카본 내화물에서는 미변질층에 비하여 변질층에서 SiO₂, Fe₂O₃,CaO, 고정탄소의 함량이 높았다. 한편, 마그크로 내화물에서는 가동면에서 산화철의 함량이 현저히 높았으며, AI₂O₃와 CaO는 가동면으로부터 침윤층까지 침투하였다. 마그크로 내화물에서는 페이클레이즈, 머위나이트, 스피넬, 크롬광이, 마그카본 내화물에서는 페리클레이즈와 흑연이 주된 광물상으로 존재하였다. 알루미나와 규산염 액상은 마그크로 내화물의 내부로 침투하여 크롬광과 반응하여 2차 스피넬을 생성하였다. 열적 및 구조적 스폴링으로 인하여 마그크로 내화물에서 주요 균열이 발생하였다. Mineral and chemical changes of MgO-C and MgO-Cr₂O₃refractories used in ASEA-SKF ladle were examined by chemical analysis, microscopy and X-ray diffraction method. The amount of SiO₂, Fe₂O₃,CaO and fixed carbon in used MgO-C refractory was high in the hot-face compared with the cold face. On the other hand, the amount of iron oxide in MgO-Cr₂O₃refractory apparently increased in working surface, and AI₂O and CaO penetrated from working surface to permeating layer. Periclase and mercantile, spinel and chromite in MgO-Cr₂O₃refractory and, periclase and graphite in MgO-C refractory existed as main minerals. Alumina and silicate liquid penetrated into the inner face of MgO-Cr₂O₃refractory and then reacted with chromite to form secondary spinel. The major crack was occurred in MgO-Cr₂O₃refractory owing to thermal and structural spalling.

o-Xylene-ethylacetate 혼합용매를 이용한 초산수용액의 액-액평형에 관한 연구

장윤식,이진우,박동원 동아대학교 생산기술연구소 1999 生産技術硏究所硏究論文集 Vol.4 No.1

Due to the rising cost of energy, new separation processes based on extraction are becoming more attractive than before. The phase equilibria of quaternary liquid-liquid extraction(LLE) system composed o-xylene-water-acetic acid-ethylacetate was investigated. The purpose of this study is to determine and describe LLE data for the quaternary system containing acetic acid aqueous solution and solvent at 25℃. We investigated that the selection of the optimum solvent to separate acetic acid from aqueous solution. The distribution and selectivity for quaternary system o-xylene(1)-water(2)-acetic acid(3)-ethylacetate(4) are increased with addition of o-xylene. These experimental tie-line data are also compared with the values predicted by UNIFAC model. It is shown that UNIFAC model is capable of predicting the tie-line in these quaternary systems within an average root mean square deviation of 4.07㏖%.

Butyl acetate-MEK 혼합용매를 이용한 초산분리에 관한 연구

장윤식,황승순,박동원 동아대학교 환경문제연구소 2000 硏究報告 Vol.23 No.1

We studied on the phase equilibria of quaternary liquid-liquid extraction system containing acetic acid-water-binary solvent at 25℃, MEK-butyl acetate were used as binary solvents. Binodal curve, tie-line, distribution and selectivity for each quaternary system have been determined in order to investigate the effect of using binary solvent in extracting acetic acid from aqueous solution. And these experimental tie-line data were also compared with the values predicted by WAC model. It was shown that UNIFAC model is capable of predicting the tie-line in these quaternary systems within an average RSDM of 3.76 mol%.

만성신장병 - 예방

장윤식 한국만성질환관리협회 1995 월간성인병 Vol.176 No.-

태권도 교육 프로그램의 개발에 관한 연구

방영진,장윤식 경희대학교 사회체육연구소 1995 體育科學論叢 Vol.- No.8

Taekwondo Education Program toward 20th century should be planned on the basis of diversified and three-dimensional view considering the feature of future Koreans and foreigners by founding the research institute studying only TaeKwonDo education program Korean TaeKwonDo should succeed the traditional culture inheritances as a suzerain and inspire national pride through a series of process ; physical checkup and exercise-prescription according to the simple Cardiac output index lasting supplement and expansion of education program, construction of the great-sphere computer networking system which enable us to use the various program through the public computer network. The aim of this study is through development and research of TaeKwonDo education program to make a transcendentl base for Korean TaeKwonDo to be activated as the sport for all and make a foundation on which TaeKwonDo is firmly established as national martial arts. At this stage that Korean TaeKwonDo is making overseas expansion in order to realize the gymnastics ideology and develop it in the desirable direction deve-lopment of education program must be made without delay So, I came to these conclusions : Korea TaeKwonDo's diffusion toward sport for all should be more accelerated and through the improvement of wrong social conception we should, in all aspects of TaeKwonDo, develop and apply systematically TaeKwonDo programs which is nation-wide, general, and beneficial as well as TaeKwonDo guidance programs(facilities, activities, objects, leader) The programs should consider the various features like as the distinction of sex and age, physical, mental, physiological, and emotional characters and we should develop and spread them step by step to the grades. In addition, The TaeKwonDo Program aim.at the scientification and rationalization of health care through development and extension of exercise-prescribed computer-programs in due consideration of Korean and foreign bodily shape. The programs also have the contents presenting TaeKwonDo training methods and joining motives and they are considered as the concrete means to guarantee the efficient and reasonable TaeKwonDo training and practical problem to enlarge TaeKwonDo population.

법과학 교육의 일반적 논점과 시사점

장윤식 이실학회(구 한국경찰이론과실무학회) 2012 경찰연구논집 Vol.9 No.-

법과학은 다양한 증거를 분석하고 여러 과학 기술을 응용할 필요가 있는 무작위적이고 조직화되지 않은 ``범죄``의 특성에 덧붙여 그 결과가 통상의 과학과정의 추론과다른 복합적 규칙을 지닌 법적 영역에서 표현되어야 하는 특별한 분야이다. 대학에서 의 법과학 교육은 전문지식의 습득과 실무기관의 훈련 부담의 절감, 연구를 통한 기여 등 여러 측면에서 확대가 될 필요가 있다. 하지만 과학 교육이 조금씩 확대되어가는 국내 사정과 달리 여러 선진국은 교육의 과잉으로 인한 문제를 겪고 있다. 이에 는 취업문제, 교육 품질 문제, 교육의 내용과 훈련 등 다른 전문성 요소와의 관계 등이 포함된다. 이에 본고에서는 주로 미국과 영국을 중심으로 법과학 교육과 관련하여인지된 문제와 이를 해결하기 위한 노력들을 살펴보고 국내 법과학 교육발전에 시사하는 바를 모색해보고자 하였다. 국내 법과학 전문인력의 수요는 크지만 이는 조직과 예산상의 문제일 따름이며, 실제 국립과학수사연구원 등 소수 기관에 집중된 신임 연구원 수급은 법과학 교육에 의존하지 않고 있어 무엇보다 법과학 교육의 활성화를 가로막는 요인은 취업 문제라고 할 수 있다. 특화된 법과학 교육에 대한 인식제고와 함께 실제 교육이 진행될 때에도 교육 품질의 인증과 국가적인 진로모델의 마련을 통한 전문성 개발의 효율화를 도모할 필요가 있으나 법과학 실무가 관련 기관별로 이루어져 이러한 기틀을 마련할법과학 거버넌스가 뚜렷하지 않다는 것이 범국가적인 제도마련의 장애요소라고 할수 있다. Forensic sciences are specialized area due to the random and unorganized nature of crimes requiring diverse evidence analysis and application of various sciences and technologies, and the result should be demonstrated in legal context requiring complicated rules, unlike ordinary scientific inferring process. In Korea, forensic education is needed to expanded regarding such aspects as acquisition of more specialized knowledge, reduction of training costs of current laboratories, and other contributions of academia including researches. In contrast, excessive amount of forensic education came into question in some countries. Difficulty in seeking a job, quality of education, and harmonization with other factors of expertise are recognized problems. This paper explores implication from the recognized issues and countermeasures mostly in the U.S. and the U.K. Needs for new recruitment in Korean forensic laboratories are increasing. It does not directly imply that more forensic education is required. Because the laboratories do not rely on forensic education to hire new employees, it is one of the most distinctive causes of inactive forensic education. Other than awareness for forensic education, such resolutions as accreditation of forensic courses for the better quality education and suggestion of career path for forensic practitioners for the better efficiency should be pursued by a forensic governance. Korean forensic governance seems not even formulated because laboratories belong to separate organizations have their own approaches for management including development of expertise.