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SIMULTANEOUS CONCENTRATION AND DETECTION OF ESCHERICHIA COLI USING CARBON NANOTUBE DEVICES
박동원,최원진,양철수,박세린,서은미,김승수,장현주,이종오,김범수 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2013 NANO Vol.8 No.5
The performance of a nanoscale sensor is not limited by the sensitivity of the sensor itself but rather by the diffusion time required for target molecules to reach to the extremely small sensor surface. In this work, we developed a carbon nanotube device that performed the dual functions of concentrating and detecting microorganisms in a sample solution. The sensor surface area was increased by fabricating a carbon nanotube network device using thermal chemical vapor deposition and standard microfabrication techniques. The target Escherichia coli (E. coli) cells were concentrated at the sensor surface via dielectrophoretic concentration by the carbon nanotube network channels. After 10 min of collection, the chip was washed with ample amounts of a clean buffer solution, and only the E. coli cells that were bound to the antibodies remained on the sensor surface. The binding of E. coli to the CNT network device decreased the conductance, presumably due to an increase in the scattering at the sensor surface. The detection limit and the time required for microorganism detection was greatly improved by combining dielectrophoresis with the carbon nanotube devices.
박동원,Park, Dong-Won 배재대학교 공학연구소 1998 공학논문집 Vol.3 No.1
This paper describes a model suitable for real-time languages, which explicitly defines a set of resource objects. The resource objects are constituted in a specialization hierarchy which allows programmers to perform resource handling at any desired level of detail, as well as providing a uniform interface. This object-oriented model is used to extend the applicability of the imprecise computation approach to deal with shortfalls of any computational resource, and enable to build real-time systems which can handle dynamic situations. 본 논문에서는 실시간 프로그래밍 언어와 적절히 연동할 수 있는 자원관리 모델을 제시한다. 시스템의 자원을 계층적으로 관리하여 일관된 인터페이스 환경을 유지하면서 미세조정까지 가능한 자원 이용환경을 제공하고자 하는 것이다. 이와 같은 객체지향 자원관리 기법은 계산 시간 부족을 처리하는 근사값 접근방법의 효과를 더욱 상승시킬 것이며, 또한 동적 실시간 시스템을 구축함도 용이롭게 할 수 있을 것이다.
초산 수용액을 포함한 4성분계에서의 용제회수에 관한 연구
박동원,장윤식,최성욱,김영일,서진기 동아대학교 환경문제연구소 1998 硏究報告 Vol.21 No.1
Due to the rising cost of energy, new separation processes based on extraction are becoming more attractive than before. Thus, the need for calculating and predicting liquid-liquid equilibria(LLE) compositions has very much increased. The purpose of this study is to determine and describe LLE data for the quaternary system containing acetic acid aqueous solution and solvent at 25℃. We investigated that the selection of the optimum solvent to separate acetic acid from aqueous solution and compared with ternary and quaternary LLE including binary solvent also.
박동원,문재영,구은영,김선종,구영모,김옥주,이순행,조민우,임채만,John David Armstrong II,고윤석 대한의학회 2015 Journal of Korean medical science Vol.30 No.4
This research aimed to investigate the changes in ethical issues in everyday clinical practicerecognized by critical care nurses during two observation periods. We conducted aretrospective analysis of data obtained by prospective questionnaire surveys of nurses inthe intensive care units (ICU) of a tertiary university-affiliated hospital in Seoul, Korea. Data were collected prospectively during two different periods, February 2002-January2003 (Period 1) and August 2011-July 2012 (Period 2). Significantly fewer cases withethical issues were reported in Period 2 than in Period 1 (89 cases [2.1%] of 4,291 ICUadmissions vs. 51 [0.5%] of 9,302 ICU admissions, respectively; P < 0.001). The highestincidence of cases with identified ethical issues in both Periods occurred in MICU. Themajor source of ethical issues in Periods 1 and 2 was behavior-related. Among behaviorrelatedissues, inappropriate healthcare professional behavior was predominant in bothperiods and mainly involved resident physicians. Ethical issue numbers regarding end-oflife(EOL) care significantly decreased in the proportion with respect to ethical issues duringPeriod 2 (P = 0.044). In conclusion, the decreased incidence of cases with identified ethicalissues in Period 2 might be associated with ethical enhancement related with EOL andimprovements in the ICU care environment of the studied hospital. However, behaviorrelatedissues involving resident physicians represent a considerable proportion of ethicalissues encountered by critical care nurses. A systemic approach to solve behavior-relatedissues of resident physicians seems to be required to enhance an ethical environment in thestudied ICU.
정상면역 환자에서 외상 후 발생한 Mycobacterium fortuitum에 의한 무릎아래주머니염 1예
박동원,김지은,백수영,박혜선,손창남,안성은,박혜정,장시형,백승삼,최충혁,최태열,배현주 대한감염학회 2008 감염과 화학요법 Vol.40 No.5
Mycobacterium fortuitum is a rare pathogen, frequently found in water, soil, animals and plant materials, It can cause infections involving skin, soft tissue and skeletal system after direct inoculation of the pathogen through surgical traumas, Punctures and injections. We report a case of infrapatellar bursitis caused by M. fortuitum in an immunocompetent, 42-year-o1d female, which occurred after bicycle trauma. She experienced marked improvement after surgical excision and debridement of the wound site and antimicrobial therapy.
진공 승화법에 의한 금속 옥시네이트 화합물의 분리거동과 물질전달
朴東源 동아대학교 공과대학 부설 한국자원개발연구소 1984 硏究報告 Vol.8 No.2
The heating temperaure, vacuum condensing point, velocity of sublimation and distance of diffusion were measured according to the change of vacuum degree of metal oxinate by vacuum sublimation method. Their corelation and separation were experimented. Mass transfer was studied with their diffusion coefficient and mass tranefer coefficient. Results obtained on the sublimatographic character of metal oxinate are as follows; 1) Vacuum condensing point of metal oxinate at different heating tomperature and vacuum degree is obtained. 2) The possibility of separation of any metal oxinate will be presumable from the th-V. C. P. curve for each component in metal oxinate. 3) The vapor pressure, molar velocity of sublimation and mass transfre coefficient of copper oxinate are calculated by experimental data; P_(h)/P_(s)=r r=1.1) P_(s)=KNⁿ (n=0.58) k_(G)=1.88×10^(-6) (at 10^(-2)㎜Hg)