퇴행성 슬관절염 환자의 증상 중증도 측정을 위한 적외선 체열상의 유용성

이두익,김건식,김수영,최도영,이상훈,이재동,이윤호 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

Objectives: To investigate the applicability of thermography as severity measurement in the patients with osteoarthritis (OA) of the knee. Methods: Data were obtained from 80 patiens with OA of the knee. They were asked to answer two disease-specific questionnaire (Western Ontario and McMaster Universities (WOMAC) OA index, Lequesne's Functional Index (LEI)), one generic instrument (Korean Health Assessment Questionnaire (KHAQ)), Visual Analogue Scale (VAS) pain intensities in order to assess the severity of disease, quality of life, and degree of pain and taken thermography in standardized environment before and after treatment, respectively. Results: The thermal differences between ipsilateral side and contralateral side in lateral aspect, medial aspect, patella region and suprapatella of both knees were correlated with pain lesion sites. Age, duration of disease, duration of morning stiffness, sex, and crepitus of knee were not correlated with the thermal differences of each regions. And also LFI, WOMAC, WOMAC pain subscale, WOMAC stiffness subscale, WOMAC physical function, KHAQ, were not correlated with the thermal differences of each region. But, the changes of VAS pain intensities were highly correlated with the thermal differences of each regions, especially in patelaa and suprapatella of knees after teratment. Conclusions: Although several specific evaluation indices for osteoarthritis of knee were not correlated with the degree of thermal differences between both knees, the differences of pain intensity (VAS) were quit correlated with thermal differences after treatment. And infrared thermography might be a very useful devices fot the evaluation of OA of knee and its treatment. Further study on the thermography on OA of the knee in more size of patients with appropriate severity grade and the standardization of analysis of thermographic data were recommended.

편두통 환자의 임상 양상 및 생체전기 자율반응과의 상관성 고찰

이현종,정인태,김수영,이두익,김건식,이재동,이윤호,최도영 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Objective : We had a clinical report in headache but didn't in migraine. We have planned this study in order to get the basic data of migraine in oriental medicine. Methods : The patient of 36 in migraine checked sec, age, onset, family history, severity of pain, influences of life, induced cause, clinical pain characteristics, associated symptom, treatment style, and paescription, frequency, using period of analgesics by a questionnaire and differentiated syndromes in migraine and evaluated autonomic bioelectric response recorder(ABR-2000). Results : There are 23.4% in prevalence rate of migraine. The ratio of sex is M: F=1:17. The age of an attack is the highest in thirties. The patient are the most in forties. The mean duration of illness is 12.0±9.9 years. 83.4% had a family history. 61.1% had a moderate grade in severity of pain. 77.8% selected fatigue in induced cause of migraine. 69.4% had tingling sense, nausea and vomiting in the associated symptoms. 91.7% used analgesics for treatment and 51.5% of them used analgesics voluntarily. 61.9% of them take analgesics less than once in a week. 33.6% had the phlegm syncope headache in differentiation of syndrome. In ABR-2000 results, item of graph showed low tendency mostly. Conclusions : We expected that this re port of clinical progress, differentiation of syndromes and ABR-2000 results in migraine would be used basic data by oriental medicine to treat migraine.

봉독약침이 류마티스 관절염 환자의 기능회복 및 삶의 질에 미치는 영향

이상훈,이현종,박상민,김수영,박재경,홍승재,양형인,이재동,최도영,김건식,이두익,이윤호 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2003 東西醫學硏究所 論文集 Vol.2003 No.-

Objective: To evaluate the effects of bee venom acupuncture(BVA) on the rehabilitation and quality of life in rheumatoid arthritis(RA) patients Methods: Patients with RA were treated with the BVA therapy twice a week for 3 months. Tender joint counts, swollen joint counts, morning stiffness, Erythrocyte Sedimentation Rate(ESR), C-reactive protein(CRP), patient global assessment, physician global assessment, Korean health assessment questionnaire(KHAQ) were estimated and analyzed before and after BVA therapy. Results: Tender joint counts, swollen joint counts, morning stiffness showed significant decrease after BVA therapy. But, as acute inflammatory reactants, ESR showed no significant difference and CRP showed significant increase after BVA therapy. Patient global assessment physician global assessment, and KHAQ index showed significant improvement after BVA therapy. Conclusions: BVA therapy can improve rehabilitation and health-related quality of life RA patients as well as clinical symptom and signs. Further study is required in more population with large scale including acute inflammatory reaction of BVA therapy.

봉독약침이 류마티스 관절염 환자의 관절 통증, 종창 및 급성 염증 반응에 미치는 영향

이상훈,이현종,백용현,김수영,박재경,홍승재,양형인,김건식,이재동,최도영,이두익,이윤호 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2003 東西醫學硏究所 論文集 Vol.2003 No.-

Objective In order to study the effects of bee venom(BV) on the pain, edema, and acute inflammatory reactant of rheumatoid arthritis(RA) patients. Methods Patients with RA who met the ACR(American College of Rheumatology) 1987 revised criteria for the diagnosis of RA were treated with the BV therapy twice a week for 3 months. Tender Joint counts, swollen joint counts, Visual analog scale(VAS), morning stiffness, ESR. C-reactive protein(CRP) were analyzed before and after BV therapy. Results The results as follows. 1. Tender joint counts in patients after BV therapy were significantly lower than those before BV therapy(9.0±7.9 vs 15± 11.4, p=0.002). 2. Swollen joint counts of the patients after BV therapy were significantly lower than those before BV therapy(50±61 vs 15±23, p=0.001). 3. VAS in patients after BV therapy was significantly lower than those before BV therapy(608± 17.6 vs 380± 159, p=0.000). 4. Duration of morning stiffness in patients after BV therapy was significantly reduced compared with that before BV therapy(119.1± 112.6 min vs 59.0±89.7 min, p=0.009). 5. ESR and CRP were not significantly changed before and after BV therapy, suggesting BV itself could make inflammatory reaction as well as therapeutic effect. Conclusions BV therapy improved tender joint counts, swollen joint counts and duration of morning stiffness in this study, and further study is needed on long-term effect of BV therapy.

블록체인이 통신업계의 가치사슬에 미치는 영향

이건수 ( Keon Su¸ Lee ) 한국지급결제학회 2020 지급결제학회지 Vol.12 No.2

2016년도의 일본경제산업성 시산에 따르면 블록체인이 영향을 미칠 가능성이 있는 시장규모가 67조엔이나 된다. 그러나 유력한 차세대 기술 중 하나인 블록체인에 대해서는 그 개요를 들은 적은 있어도, 자사의 사업에 어떠한 영향을 초래할지를 상상하고 있는 사람은 많지 않다. 비트코인에서 사용되는 기술을 바탕으로 거대한 시스템에서 데이터를 집중 관리하지 않고도 가치 기록이 요구되는 다양한 활용 사례에 대응 가능한 시스템으로 추출된 것이 블록체인이며, 현 시점에서는 금융계 Fintech의 활용사례가 앞서 검증되고 있다. 블록체인은 데이터 변조가 어렵다. 데이터 변경 이력을 시계열로 기록정보를 공개검증 가능성이 다운되지 않는 시스템 구성, 비교적 저비용으로 구축 가능이라는 특성을 가지면서도 현 시점에서는 개발 중인 기술로 보안 향상 외에 처리성능, 운용비용, 편리성, 확장성 등 해결해야 할 과제는 복합적으로 존재한다. 한편, 블록체인 기술은 향후 발전 가능성을 감안할 때, 아직은 여명기라고 할 수 있다. 인터넷이 정보를 혁신했듯이 블록체인은 가치에 대해 비슷한 혁신을 일으킬 가능성을 내포하고 있다. 이전의 PC통신과 같이 중앙집권적인 틀에서 공유되던 정보는 메일이나 www로 공유되는 시대로 넘어가 블로그, SNS 등 인터랙티브성을 가진 Web2.0 시대를 거쳐 IoT 시대로 진화하는 흐름 속에서 사회에 큰 영향과 혁신적인 발전을 가져왔다. 이와 마찬가지로 블록체인이 만들어 낼 혁신이 향후 사회를 크게 발전시키리라고 기대할 수 있다. 본 논문은 금융업계와 함께 블록체인과의 관계가 깊은 사회 인프라인 통신업계에서 블록체인의 의의, 영향을 살펴보고 있다. 블록체인이 가지는 성질상, 어느 통신 사업자가든 한 회사에서 맞붙는 테마가 아니기 때문에 해외 통신 사업자와의 공동 검증 활동 등 서서히 컨소시엄형의 대응이 나타나고 있다. 몇 가지 유스 케이스에서의 실제 비즈니스화가 진전되어 감과 동시에, 21세기의 가장 중요한 인프라 중 하나인 통신업계에는 블록체인 기술을 중장기적인 시점에서 파악해 계속적으로 이노베이션을 창출하는 기점이 되기를 기대한다. 본고의 내용이 그에 도움이 된다면, 더할 나위 없는 기쁨이다. According to the estimate by the Ministry of Economy, Trade and Industry in 2016, the market size that the blockchain could have an influence on is 67 trillion yen. However, even if you have heard an overview of blockchain, one of the most promising next-generation technologies, few are imagining how it will affect their business. Based on the technology used in Bitcoin, blockchain was extracted as a system capable of responding to various use cases that require value recording without centrally managing data in a huge system. Blockchain is difficult to alter data. A system configuration that does not reduce the possibility of public verification of data change history as a time series, and can be built at relatively low cost, but is a technology under development at this time, in addition to improving security, processing performance, operating cost, convenience, and expandability. There are complex tasks to be solved. Meanwhile, considering the potential for future development of blockchain technology, it can be said that it is still a dawning period. Just as the Internet has revolutionized information, blockchain has the potential to bring about similar innovations in value. Information that was shared in a centralized framework like PC communication in the past has moved to the era of sharing via email or WWW, and has a great influence on society in the evolution of the IoT era through the Web2.0 era with interactive features such as blogs and SNS. And brought innovative developments. Likewise, it can be expected that the innovation that the blockchain will create will greatly improve society in the future. This paper examines the significance and impact of blockchain in the telecommunications industry, a social infrastructure that has a deep relationship with the blockchain with the financial industry. Due to the nature of blockchain, no telecommunications operator is a theme that one company faces, so a consortium-type response is gradually appearing, such as joint verification activities with overseas telecommunications operators. As the actual business activation progresses in several use cases, I expect that blockchain technology, which is one of the most important infrastructures of the 21st century, will be grasped from a mid- to long-term perspective to continue to create innovation. If the contents of this article are helpful to that, it is a joy.

만성두통환자에 대한 동서협진의 임상적 연구

정인태,이상훈,김수영,차남현,김건식,이두익,이재동,임사비나,이윤호,최도영 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

Objective : Because the cause and etiology of chronic headache are not yet fully explained, the treatment of this symptom is not simple. In order to study the effectiveness East-West pain treatment on chronic headache, we evaluated its effect of pain alleviation and quality of life improvement on chronic headache patients who were treated with nerve block and acupuncture, and only acupuncture for eight weeks. Methods : 92 clinical experiment participants were gathered and through a questionnaire patients who experienced headache for more than 4 hours a day and more than 15 days per month were qualified as chronic headache patients. The qualified patients were classified into two groups, nerve block and acupuncture group(EW group, n=49) and acupuncture group(E group, n=43). Treatment was applied 2 times a weeks for 8 weeks. The acupoints, GV20, HN23, ST8, HN46, TE17, GB20, LI20, LI11, LI14, ST36, and LR3 were stimulated for 20 minutes. The effects of two groups were analyzed using VAS scores and BPI(Brief Pain Inventory). Results : The VAS and BPI after four weeks of treatment showed significant improvement among two but differences between the three groups was statistically insignificant. The VAS and BPI of the EW group after eight weeks of treatment showed statistically significant improvement compared to the other two groups. Conclusion : The pain treatment for chronic headache might be contributed to improvement of quality of life as well as alleviation of pain of chronic headache patients. It was suggested that the West pain treatment in combination with East pain treatment might be an useful modality to improve the pain and quality of life in chronic headache patients.

만성두통환자에 대한 침치료가 심박변이도에 미치는 영향

정인태,이상훈,김수영,차남현,김건식,이두익,이재동,임사비나,이윤호,최도영 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

Objective : The purpose of this study was to assess the effect of acupuncture treatment for chronic headache patients using power spectrum analysis of the heart rate variability(HRV). Methods : 15 clinical experiment participants were gathered and through a questionnaire patients who experienced headache for more than 4 hours a day and more than 15 days per month were qualified as Chronic Headache patients. Treatment was applied 2 times a weeks for 8 weeks. The acupoints, GV20, HN23, ST8, HN46, TE17, GB20, LI20, LI11, LI14, ST36, and LR3 were stimulated for 20 minutes. The effects of acupuncture treatment were analyzed using power spectrum analysis of the HRV, HRV was recorded before and after acupuncture treatment. Results : HRV before and after treatment was compared after 8 weeks of acupuncture treatment. Increase in mean values of SDNN and RMSSD were observed but the increases were not statistically significants. Increase in mean values of TP, LF and HF were observed but, the increase was significant(p<0.05) only in TP. Conclusions : The results suggest that acupuncture treatment on chronic headache patients can increase the activity of autonomic nervous system. Further use of HRV for quantitative analysis of acupuncture treatment on autonomic nervous system related symptoms is suggested.

제통단이 퇴행성 슬관절염 환자의 삶의 질에 미치는 영향

서병관,류성룡,강중원,우현수,이상훈,이재동,최도영,김건식,이두익,이윤호 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

Objectives : to evaluate the effects of Jetongdan, the newly developed herbal medicine, on the quality of life in patients with osteoarthritis of knee Methods : Placebo-controlled, randomized clinical trial on the 80 patients with osteoarthritis of the knee was fulfilled. After enrollment, they took medication as they enrolled. And they were asked to answer the questionnaires (Korean Health Assessment Questionnaire (KHAQ), Lequesne's functional index (LF1), visual analogue scale (VAS)) and analysed with the erythrocyte sedimentation rate (ESR) at baseline, after 4 weeks and 8 weeks of medication. Results : Total KHAQ score, some categories of KHAQ like hygiene, activities were significantly improved after 8 weeks of medication. And the change of the KHAQ score was significantly correlated with the change of VAS. But LFI, VAS, ESR level was not significantly improved, and it was considered because of the short medication period and small size of study population. Conclusion : In conclusion, Jetongdan could improve the health-related quality of life in patients with osteoarthritis of knee. Further study in the large population, in long period were recommended.

만성두통 환자의 성격유형 A 행태, 스트레스, 우울 및 두통영향정도의 관계 연구

차남현,임사비나,정인태,김수영,안경애,김건식,이재동,이상훈,최도영,이윤호,이두익 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

To examine an estimate factor and grasp the relation of difference for Ype A Behavior Pattern(TABP), Perceived Stress Questionnaire. Depression and HIT-6 in the Chronic headache client. Method: Data collected by self-reported questionnaires from 38 client in S city who were selected by criteria of IHS, from the 19^(th) of October to 10^(th) of December, 2004. Result: 1) Differences between biographical data by TABP was significant by SaSang constitutions, by Stress was significantly influenced by age, and by Depression were significantly influenced health status and SaSang constitutions. 2) Correlations Coefficients among Study Variables were Stress and Depression(r=.494, p=.002) and Depression and HIT-6(r=.432, p=.010). 3) In regression analysis, HIT-6 were significantly influenced by Depression and Type A Behavior Pattern(TABP). These variables explained 38% and 34% respectively. Conclusion: The result suggest that chronic headache management with psychological aspect, as well as physical aspect should be a focus to enhance the quality of life.

신경세포 이주장애에 관한 연구

이건수,안인철 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.1

25 cases under 15 years of age with neuronal migration disorders were observed at the department of Pediatrics at Chungnam National University Hospital during a period of 6 years from January, 1992 to December, 1997. The results were as follows: 1. The peak incidence of age was 5 to 10 years(40.3%). The sex ratio of male to female was 1.8 : 1. 2. The types of neuronal migration disorders were cortical dysplasia (36%), lissencephaly(28%), schizencephaly(16%), heterotopia(12%) and megalencephaly(8%) in order of frequency. 3. The clinical findings were seizure(76%), delayed development(48%), delayed speech(32%), mental retardation(24%) and motor deficit(20%) in order of frequency. 4. The locations of disorder were frontal lobe(72%), parietal lobe(60%), temporal lobe(40%) and occipital Iobe(32%) in order of frequency. 5. The abnormal EEG findings were 17 cases(68%). Among these cases, focal abnormalities were 5 cases(29.4%), general abnormalities were 11 cases(64.7%) and abnormal background was 1 case(5.9%). 6. The seizure types were generalized seizure(63.2%), partial seizure (31.6%) and mixed seizure (5.3%) in order of frequency. 7. The patients with larger size of lesions had more delayed development, delayed speech and mental retardation.