1980年 慶北地方 優良兒 選拔大會에 參加한 영유아의 成長發育에 對한 考察

李健秀 慶北大學校 醫科大學 1980 慶北醫大誌 Vol.21 No.2

1980年 慶北地方 優良兒選拔大會에 參加하였던 영유아(7~24個月兒) 431名을 對象으로 하여 이들의 各種 身體計測値 및 血淸蛋白量, 血色素値, 비타민 D 缺乏症狀을 살펴본 結果 다음과 같은 結論을 얻었다. 1. 體重에 있어서 韓國標準値 및 日本平均値와 比較하여 男女 모두 2.40~3.28kg과 1.31~2.07kg 우위에 있었고 身長 역시 3.26~6.01cm 및 0.89~3.51cm 優位에 있었으며 胸圍 및 頭圍에 있어서도 各 1.85~3.49cm, 1.70~2.65cm 및 0.66~l.86cm, 0.02~0.52cm씩 優位임이 測定되었다. 2. 皮膚두께 測定値에서 Triceps skin fold thickness가 洪等의 計測値에 비해 男兒는 2.30~2.58mm, 女兒는 2.73∼3.70mm, Scapular thickness에서는 男兒 1.20~1.80mm, 女兒가 0.73~1.03mm 우위에 있었다. 3. 上腕둘레는 洪等의 計測値보다 男兒 1.27∼2.43cm, 女兒 2.25~2.80cm 優位에 있었다. 4. Hand refractometer를 使用하여 測定한 血淸蛋白量은 男兒平均 7.67gm%, 女兒 7.7gm%로서 年齡別 差異는 없었다. 5. Kaup指數 20以上은 男兒에서 16.4%, 女兒 13.8%로 나타났다. 6. 授乳方法에서는 混合營養이 가장 많아 41.8%였으며 다음이 母乳, 人工營養의 순서였다. 7. 離乳時期는 48.5%가 4~6個月에 始作하여 1年 以內에 大部分(95.3%)이 始作한 것으로 나타났다. 8. 血色素値 10.5gm% 미만을 貧血로 잡았을때 15.3%가 여기에 해당했고 이들은 철분 투여시 6.5%, 투여하지 않는 경우 9.5%였다. 9. 비타민 D 缺乏症狀의 頻度는 1.4%였으며 人工營養, 混合營養의 차례로 나타났다. Authors have conducted a study on 431 infants panticipated in Kyungpook regional well baby contest, hold in 1980. After throughout investigation of several parameters including physical development and nutritional status such as serum protein, Kaup index, hemeglobin and sign of possible vitamin D deficiency, the following results were obtained. Comparing the body weight, height, chest and head circumfernce with Korean Children's Growth Standard(K.S.) and Japanese Children's Growth Standard(J.S.), their body weight were superior of those of K.S.(2.40-3.28kg) and J.S.(1.31-2.07kg), their body length also superior to those of K.S.(3.26-6.01cm) and J.S.(0.89-3.51cm). Triceps skin fold thickness and Scapular thickness were superior to those of Hong(2.30-3.70mm, 0.73-1.80mm), the arm circumference was superior to those of Hong (1.27-2.80cm), too. The kaup index was over 20, considered to be overweight, in 16.4% in boys and 13.8% in girls. Mixed feeding was the most common form of infant feedings, comprising 41.8%, followed by breast feeding and bottle feeding. Weaning was started within 4-6 months of age in 48.5% of infants and the majority within 12 months of age(95.3%) The total mean serum protein was 7.67gm% in boys, 7.71gm% in girls and no difference was found between various age groups. 15.3% of those infants showed anemia, using the criteria of as being hemoglobin less than 10.5gm%. They were found in 6.5% iron supplementation group, and 9.5% on infants group without iron supplementation. In 1.4% of infants, there were signs of possible vitamin deficiency including Harrison's groove.

Guillain-Brarre´ 증후군에 관한 연구

이건수 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

A clinical study was performed on 40 cases of Guillain-Barre´ syndrome which were seen at the department of pediatrics, Chungnam National University Hospital, during the past 10 years from October 1985 to October 1995. The results were as follows : The ratio of male to female was 1.5 : 1 and 50% of the total cases were noted between the age of 1∼5 years. U.R.I was the most common antecedent illness (50∼60%) and preceding illness was found in 65% of the total cases. Muscle weakness was found in all cases. The physical findings were paralysis of upper and lower extremities in 70%. cranial nerve involvement in 50%, paralysis of lower extremity in 30%, involvement of respiratory muscle in 15%, etc. The protein content of C.S.F was elevated in 55% on admission, and in 90% on one week later. The W.B.C count of C.S.F was elevated in 10% (over 10/mm) and the pressure of C.S.F was increased in 15% (over 200mmH_2O). Ninety percent of total cases improved on discharge and the mortality rate was 2.5%. The duration of recovery was less than 4 months in 93.8% of the total cases.

신경세포 이주장애에 관한 연구

이건수,안인철 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.1

25 cases under 15 years of age with neuronal migration disorders were observed at the department of Pediatrics at Chungnam National University Hospital during a period of 6 years from January, 1992 to December, 1997. The results were as follows: 1. The peak incidence of age was 5 to 10 years(40.3%). The sex ratio of male to female was 1.8 : 1. 2. The types of neuronal migration disorders were cortical dysplasia (36%), lissencephaly(28%), schizencephaly(16%), heterotopia(12%) and megalencephaly(8%) in order of frequency. 3. The clinical findings were seizure(76%), delayed development(48%), delayed speech(32%), mental retardation(24%) and motor deficit(20%) in order of frequency. 4. The locations of disorder were frontal lobe(72%), parietal lobe(60%), temporal lobe(40%) and occipital Iobe(32%) in order of frequency. 5. The abnormal EEG findings were 17 cases(68%). Among these cases, focal abnormalities were 5 cases(29.4%), general abnormalities were 11 cases(64.7%) and abnormal background was 1 case(5.9%). 6. The seizure types were generalized seizure(63.2%), partial seizure (31.6%) and mixed seizure (5.3%) in order of frequency. 7. The patients with larger size of lesions had more delayed development, delayed speech and mental retardation.

Thanatophoric Dwarfism

李健秀 慶北大學校 醫科大學 1980 慶北醫大誌 Vol.21 No.2

One case of thanatophoric dwarfism is presented. We experienced characteristic clinical and X-ray findings including, large skull with frotal bossing, depressed nasal bridge, narrow thorax, and shortened and bowed extremities. The female baby was stillborn. Diagnosis was confirmed by Roentgenographic findings. We are reporting our experience of the patient with the reviews of the literature.

간질 환아의 혈청 지질에 관한 연구

이건수,안인철 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.2

Purpose : To assess the changes of treatment of phenobarbital, carbamazepine, valproic acid and polytherapy on serum lipids in epileptic children. Method : We determined serum levels of total cholesterol(TC), high-density lipoprotein cholesterol(HDL-C), low-density lipoprotein cholesterol(LDL-C), and triglycerides in 50 healthy children and in 80 children with epilepsy who had been receiving phenobarbital(9 patients), carbamazepine(20 patients), valproic acid(30 patients), or polytherapy (21 patients) Results : In the group receiving phenobarbital, mean TC, HDL-C and LDL-C levels were significantly higher than in the control group. In the group receiving carbamazepine, mean TC levels were significantly higher than in the control group. In the group receiving valproic acid, mean triglyceride and HDL-C levels were significantly lower than in the control group, but mean LDL-C/HDL-C ratio were significantly higher than in the control group. In the group receiving polytherapy, mean TC and LDL-C levels were significantly higher than in the control group. In neither group did mean TG/HDL-C ratio differs significantly from the corresponding control groups. Conclusion : Our results suggest long-term treatment of anticonvulsants significantly modify serum lipids in epileptic children.

소아 입원 환아의 결핵 반응 양성율에 관한 연구

이건수,권오균 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.2

A clinical study was made on 264 cases of in-patients who had been admitted at Pediatric Department, Chungnam National University Hospital from January 1985 to December 1986. The Mantoux test was performed and B. C. G. vaccination coverage rate was assessed. The results were as follows: 1. The B. C. G. vaccination coverage rate was 90.5% in urban ares, and 89.5% in rural area. 2. The positive rate of the Mantoux test in urban area was 7.8% in B. C. G. vaccinated cases, and 6.3% in B. C. G. non-vaccinated cases. 3. The positive rate of the Mantoux test in rural area was 9.4% in B. C. G. vaccinate cases, and 20% in B. C. G. non-vaccinated cases which was higher than that in urban area. 4. The positive rate of the Mantoux test was highest in 6-12 years(20.6%) and followed as decreasing orders, more than 12 years(11.1%), 3-6 years(10%), and less than 1 year (4%). 5. The postivie rate of the Mantoux test was 10% in boys, and 6.7% in girls. The sex ratio of male: female was 1.5:1. 6. The confirmed cases as tuberculosis of the Mantoux test positive cases was 26.1% and was significantly higher than that in other diseases.

신생아 Apgar Score에 관한 연구

이건수 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.1

This clinical study was made on 1000 newborns delivered at the Chungnam University Hospital in 1982-1985 to figure out any relations between Apgar score and problems such as gestational period, birth weight, maternal age, delivery type, meconium staining, and mortality. The results were summerized as followings: 1. The distribution of 1-minute Apgar score was 3.7% for score 0-3, 10.8% for score 4-6, 85.5% for score 7-10, and 5-minutes Apgar score was 2.3% for score 0-3, 2.3% for score 4-6, 95.4% for score 7-10, 5-minutes Apgar score was higher than 1-minute Apgar score. 2. The Apgar score of preterm & postterm newborns were lower than term, especially less than 32 weeks gestational age. 3. There was a trend to lower score in the newborns of the less than 2500 gm or more than 3500 gm. 4. There was no significant differance between maternal age and Apgar score. 5. The Apgar score of C-section delivery was lower than spontaneous & vaccum delivery. 6. There was a trend to lower Apgar scores in the newborns of meconium staining. 7. Perinatal death rate was 3.1% of all newborns, and mortality was higher in low Apgar score. Mortality of 5-minutes Apgar score was more significant than 1-minute Apgar score.

BCG 접종후 결핵반응 추이에 관한 연구

이건수 충남대학교 의과대학 지역사회의학연구소 1981 충남의대잡지 Vol.8 No.2

A author performed tuberculin tests following B.C.G. vaccination to 121 children under 5 years of age during the period of 6 months from Aug. 1980 to Jan. 1981 in order to clarify the time converted from negative to positive reaction following vaccination and compare two dried vaccines made in Korea and Japan on its effect on tuberculin test and side reaction. The results were as follows : 1. Positive rate of Mantoux test before BCG Vaccination was 4.9% and peaked at 3 to 4 years. 2. Abnormal chest P-A of positive tuberculin test prior to BCG vaccination was 66.6% and pulmonary tuberculosis was 3.3% of total cases. 3. Positive conversion rate of tuberculin reaction after BCG vaccination peaked at 29.1% in 6 weeks and total positive conversion rate was 86.4%. Positive conversion reaction was usually detected from 2 weeks to 10 weeks. 4. Positive tuberculin rate became higher with age. 5. Positive BCG induration after BCG vaccination peaked at 30.9% in 4 weeks and general positive BCG rate was 83.6% of total cases. Positive BCG rate was higher than positive tuberculin reaction until 4 weeks and lower than thereafter 6. The degrees of reaction between BCG and tuberculin tests were well proportional 7. Positive conversion rate of Korean BCG vaccination was higher than that of Japan BCG vaccination, and their side reactions were similar in two groups. 8. Side reaction of BCG vaccination was encountered in 6.3% of total cases.

小兒 白血病의 臨床的 觀察

李健秀,金鍾煥,安斗洪,崔正憲,黃基錫 慶北大學校 醫科大學 1974 慶北醫大誌 Vol.15 No.2

A total of, 135 cases of leukemia in children seen at Kyungpook University Hospital from July, 1966 to June 1974 were reviewed with the following results 1) Male patients were more prevalent being male to female ratio 2.23:1 2) The 4-6 years old age group showed the highest morbidity (33.3%), Generally the older children had tendency of being affected more frequently 3) One hundred and thirty two patients with Leukemia were acute type, among which lymphoblastic 93, myeloblastic 23, Monocytic 10, progranulocytic 6. The remaining 3 cases were chronic myelogenous leukemia. 4) The chief complaints in order of the frequency were pallor (58%), fever (57%), hemorrhage or Purpura(54%) and weakness (36%) The bleeding tendency was more common in acute myeloblastic leukemia than acute lymphoblasitc leukemia. 5) Hepatomegaly was observed in 71% of patients, splenomegaly, hepatosplenomegaly and ymphadenopathy 54% 46% and 47% respectively. These were more frequently noted in acute lymphobalstic leukemia than other acute type of leukemia. 6) Hemoglobin level below 10.0gm% were seen in 98%. 7) The leukocyt counts were variable but the tendency of the leukocytosis was found. 8) Thrombycytopenia was noted in 86% of the patients studied. The platelet counts were correlated with the degree of bleeding diathesis.

소아 경련의 임상적 연구

이건수 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

I have observed clinically about 236 patients of convlsive children admitted to the Pediatric Departiucnt of Chungman National University Hospital from Jan. 1989 to Dec. 1990. The results were as follows: 1) The most common cause of convulsions in children was febrile convulsion (24.6%), followed by meningitis(23.7%), epilepsy(13.6%), encephalopathy(12.7%), and encephalitis(5.9%). 2) In the sex distribution, male to female ratio was 1.3:1 3) Convulsions were most frequent in children from 1 to 5 years(48.7%), On the other hand convulsions were most least in children from 10 to 15 years. 4) The most common cause of febrile convulsion was acute pharyngotonsillitis (55.2%), and the next was U.R.I(10.3%), acute gastroenteritis(8.6%), and pneumonia(6.9%) in order of frequency. 5) The most common cause of epilepsy was encephalitis(6.3%) and idiopathic in 84.4%. 6) The most common clinical epilepyic type was generalized seizures(46.9%), followed, by partial seizures(37.5%), unclassified seizures(9.4%), and addendum(6.2%).