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김윤옥, 박성미 공주교육대학교 초등교육연구소 2005 초등학교교육연구 = Elementary school education research Vol.5 No.-
The purpose of this investigation was to analyze the actual condition of the year 2005 transferred students in the Gongju National Univ. of Education in terms of their demography, family background, social economic status, attitudes toward the University, values, psychological characteristics, attitudes toward the Research and Service Center for Students. Among 123 transferred students, 122 (99.1%) students replied to the investigation and were analyzed. The results lead to the following implications. First, most students’ age distribution went up due to the policy of the Ministry of Education to give an opportunity to those with teacher certificate who have never hired since 1970s. Second, they showed high expectancy toward becoming a teacher. Third, they revealed significant consideration about the moral and self-centered problems in the society. Fourth, they might be necessary for counseling or psychological supports to survive in the campus life because the age discrepancy between the transferred and normal undergraduate students are too wide to get along with each other in a campus, and they were worry about survival on the campus. Fifth, they revealed less problem about social relationships but more worries on faculty-student relationship, which seems to be related to their age.
생태 유아교육에 대한 교수, 원장 및 교사의 인식에 관한 연구
임재택,김성옥 부산대학교 영유아보육연구소 2000 영유아보육연구 Vol.6 No.-
The purpose of this research is to find out the level of understandings of professors, directors, and teachers about ecology centered early childhood education. This research is to outline the direction the ecology centered early childhood education should take. Below are the research problems that are dealt with in this research. First, what are the understandings of professors, directors, and teachers about the status of current ecology system? Second, what are the understandings of professors, directors, and teachers to the present early childhood education? Third, what are the understanding of professors, directors, and teachers about ecology centered early childhood education? Fourth, what are the ideas of professors, directors, and teachers about the preconditions and problems that arise when practicing the ecology centered early childhood education? The research targets used in this research are a total of 526 people ; 71 professors from the departments of Early Childhood Education and Child & Family Studies located in the Pusan, Ulsan, Kyung-nam areas and 88 directors and 367 teachers of both private and public kindergartes and child care centers. The research tool used for this research is a questionnaire asking the 'understandings of professors, directers and teachers about the ecology centered early childhood education' that has 48 questions including the forty cπle 5-ponts rating scale asking about each research target. The summaries of the important results of this research are listed below. First, for the understanding of the ecology system, all three research targets did not have the tendency for firmly favoring the ecology system. However, they recognize the crisis of environment and know why this crisis is occurring, Also, they have the understanding that to know why this crisis one has to know the limits of technology, the policy of the government has to be changed, and proper education has to be given. Second, to the understanding of the present early childhood education, there are some difference of understandings, but they recognized that the present early childhood education is not nature based but mostly technology based and they are not satisfied with the present system. This shows that they understand that the present technology oriented early childhood education has to be changed to the ecology early childhood education. Third, for this change to happen, new ecology centered early childhood education programs have to be made and applied, Also, the present early childhood education with the education system of promoting teachers and directors has to be changed to a whole new direction.
Seong, Jin Hyo,Kim, Dong Kie,Shin, Kwang Yong,Kim, Byung Ock,Kim, Myong Soo,Kim, Mi Kwang,Kook, Joong Ki 대한구강보건학회 2002 大韓口腔保健學會誌 Vol.26 No.4
본 연구는 치주질환과 관련된 병원성 세균 중 그람 음성 협기성 세균 종인 Prevorella intermedia (P. intermedia)와 Prevotella nigrescens (P. nigrescens)를 동시에 동정 및 검출할 수 있는 중합효소연쇄반응 프라이머를 개발하기 위하여 시행하였다. 모든 세균 종에 있어서 165 라이보송 RNA의 염기서 열에는 잘 보존된 부위와 종에 따라 다양한 부위가 있다. 이러한 특성을 이용하여 P. nigrescens와 P. intermedia의 알려진 165라이보솜 RNA의 염기서 열을 분석하여 두 세균 종에 공동으로 존재하는 하나의 프라이머와 각각의 세균 종에 특이하게 존재하는 다른 프라이머를 설계 및 제작하였으며, 이때 설계된 프라이머의 이름을 각각 Pin-F, Pi-R 및 Pn-R이라고 명명하였다. 이들의 종 특이성을 조사하기 위해 두 균주의 P. intermedia와 P. nigrescens지놈 DNA를 추출하여, 종 특이성을 중합효소연쇄반응법으로 관찰하였다. 이때 구강 내 6가지 다른 세균 종에서 같은 방법으로 중합효소연쇄반응을 실시한 결과 P. nigrescens와 P. intermedia 두 종만을 특이하게 검출함을 알 수 있었다. 또한 민감도를 조사하기 위해 두 세균 종에서 추출한 지놈 DNA를 4 ng에서 4 fg까지 희석하여 중합효소연쇄반응을 실시한 결과 400 fg의 지놈 DNA까지도 검출할 수 있었다. 이러한 결과를 종합할 때 이들 Pin-F, Pi-R 및 Pn-R프라이머 쌍은 P. inermedia와 P. nigrescens를 동시에 종특이적이며, 민감도 높게 검출 및 동정할 수 있을 것으로 사료된다.
Kim, Kyung Hee,Kim, Jin Man,Choi, Yoon-La,Shin, Young Kee,Lee, Ho-chang,Seong, In Ock,Kim, Bum Kyung,Chae, Seoung Wan,Chung, Yun-Shin,Kim, Seok-Hyung Blackwell Publishing Asia 2009 Pathology international Vol.59 No.5
<P>The aim of the present study was to determine the expression profile of the hedgehog (Hh) signaling molecules in normal, hyperplastic, and carcinomatous uterine endometrium. For this purpose, 271 endometrial tissue samples, (62 of normal endometrium, 127 of endometrial hyperplasias, and 82 endometrial adenocarcinomas) were studied using antibodies recognizing Hh-related signaling proteins, such as, sonic hedgehog (Shh), Patched (PTCH), Smoothened (Smo), Suppressor of fused [Su(Fu)], Gli-1, Gli-2, and Gli-3 by immunohistochemistry. The mRNA expression of these molecules was also assessed on reverse transcription–polymerase chain reaction. In the normal endometrium, the expression of Hh signaling molecules was generally downregulated except for Su(Fu), Gli-2, and Shh. In particular, the expression of both PTCH and Smo was very low or almost absent. Overall expression of Hh signaling molecules increased in hyperplastic endometrium; in particular, PTCH and Smo were significantly highly expressed in complex and atypical hyperplasia. In carcinoma samples extensive alterations were observed in the expression pattern of the signaling molecules. Nuclear Gli-2, cytoplasmic Gli-3, and Su(Fu) were overexpressed, whereas Shh, PTCH, and Smo expression were significantly reduced compared with the hyperplastic endometrium. The results suggest that the alteration of Hh signaling may be implicated in tumorigenesis of the endometrium.</P>
Kim, Ju-Ock,Kim, Hyung-Soo,Kim, Sun-Young,Jeong, Seong-Soo,Heo, Ho-Jin,Seok, Jeong-Ho,Lee, Choong-Jae The Korean Society of Pharmacology 2005 The Korean Journal of Physiology & Pharmacology Vol.9 No.3
In this study, we investigated whether sphingosine-1-phosphate, furosemide, and indomethacin affect mucin release from airway goblet cells. Confluent primary hamster tracheal surface epithelial cells were metabolically radiolabeled and chased for 30 min or 24 hr in the presence of varying concentrations of the above agents to assess the effects on $^3H-mucin$ release. Sphingosine-1-phosphate stimulated mucin release during 30 min of treatment period in a dose-dependent manner. However, furosemide and indomethacin showed no effect on both basal and stimulated mucin release during 30 min or 24 hr of treatment period. We conclude that sphingosine-1-phosphate can affect mucin release by directly acting on airway mucin-secreting cells.
생활의 질적 향상을 위한 부엌의 작업대 및 수납장에 관한 연구
김여은,김은주,김재희,김현애,김희경,성은희,옥여명,이선희,전연희,조성진 연세대학교 생활과학대학 1985 婦學 Vol.18 No.-
The purpose of this study was to examine present conditions of kitchen work centers and cabinets and to determine responses of residents in relation to them. The sample comprised of 42 households in Seoul. A questionnaire was developed, which consisted of three parts; sociodemographic information of the households, present conditions of kitchen work centers and cabinets, and their responses in relation to them. Data was analyzed by hand, using frequency and percentage. Findings from this study were as follows: 1. L shape and one wall kitchen shape were dominated, 55.0% and 32.0% respectively. The kitchen work centers were arranged most frequently in sequence of refrigerator center, sink center, mixing center, cooking center, and serving center. 2. Widths/heights of kitchen work centers and cabinets were close to the recommended measurements, however the vertical distance between the top line of kitchen work centers and the bottom line of wall cabinets showed higher than the recommended measurement. 3. Residents were satisfied to some degree with the sequence of arrangement, heights, widths, design, and color of kitchen work centers and cabinets, however they need more storage space. 4. The functional aspect and design were the major factors influenced residents' decision making for the buying behavior of the kitchen work centers and cabinets.