λ-경쇄형 다발성 골수종 1예

박용관,김태원,장영,김진호,강정원,천영욱,박유환,정춘해 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

Multiple myeloma is a disease caused by neoplastic plasma cells that synthesize abnormal amouts of immunoglobulin or immunoglobulin fragments. Light chain myeloma are regarded as a separate category characterized by a more malignant clinical course. Light chain myelomas are said to grow fastest of all and are associated with more osteolytic lesions, more hypercalcemia, and a higher incidence of renal failure and amyloidsis than either the IgG, IgA varienties The authors experienced a case of patients with λ-light chain myeloma. A 43-year-old male patient admitted to our hospital with the chief complaint of both rib and lower back pain. The radiologic findings showed multiple pathologic fracture in ribs. osteolytic lesions in 2nd, 3rd cervical spineimmuture plasma cells. Serum electrophoresis showed normal finding. Urine electrophoresis evealed an M-spike. Urine immunoelectrophoress demonstrated λ-monoclonal protein. With the cycle of melphalan, prednisone and α-interferon chemotherapy improved of pain was observed. So we reported the case with brief review of previous literature.

오픈케이슨기초의 침하촉진을 위한 AIR-JET 공법의 적용성 분석

박진원,류제천,임희대 忠南大學校 産業技術硏究所 2003 산업기술연구논문집 Vol.18 No.2

By air jet method, settlement time was much decreased and settlement was reached even to the depth which conventional method could not. The friction reduction increased more than 20 to 30%. In addition to this merits, air jet method can make caisson settlement without separating loading or increasing dead loads. By this method, size of caisson sections can be reduced for resulting in tremendous cost reduction. Also, caisson damage by blasting can be prevented with this method.

증발잔류 광물의 광물학적 연구

박천영,박신숙,김성구,조갑진,임성수 조선대학교 에너지.자원신기술연구소 2003 에너지·자원신기술연구소 논문지 Vol.25 No.1

This study has focused on mineralogical and geochemical characteritics of evaporated minerals from the mine waters and on variation of constituents in mine water during the evaporation The evaporated minerals are shown in mine waters at the field. In order to form of evaporates in the laboratory, mine waters were sampled from the abandoned mine area(HS, LG and BJ) and were air dried in laboratory for room temperature. During the evaporation of mine waters, TDS, EC values and the concentration of major and minor ions increased, whereas dissolved oxygen(DO) values decreased with the sampling time. Gypsum, epsomite, kaolinite, dolomite and illite were identified in BJ sample, gypsum and epsomite were observed in LG sample, and gypsum, epsomite and vermiculite were founded in HS sample by x-ray powder diffraction studies. The infrared spectra for evaporated minerals show major absorption banded due to OH stretching, adsorbed molecular water and sulfate stretching, respectively. Evaporated minerals were heated at 65, 150, 250 and 350℃ for 1 hour in electrical Furnaces. Gypsum transformed the bassanite at 150℃ heating temperature and epsomite transformed the hexa-hydrite at 65℃, and then converted the kieserite at 250℃. With increasing heating temperature, the intensity of absorption OH band(3407 11㎝^(-1)), adsorbed molecular water band (1654.39㎝^(-1)) and sulfate stretching band (1113.46㎝^(-1)) were decreased, whereas sulfate stretching bands(668.35㎝^(-1) and 603.85㎝^(-1)) were relatively increased in IR due to dehydration.

癎疾患者의 局所的 腦血流

田珍淑,朴容九,廉夏勇 大韓神經精神醫學會 1988 신경정신의학 Vol.27 No.2

Although nuclear tomography had begun in 1959 by Kuhl, investigators has been interested in the SPECT since 1970s. Among various radionuclide tracers, technetium(Tc99m) has been known to be more available because it can be easily permeable through the blood-brain barrier, adequately retentive, and widely usable in the clinical field because of it's lower costs than the positron emission tomography(PET). So, 99m Tc-HMPAO SPECT has been used in the studies on cerebrovascular diseaese, dementias, epilepsy, tumor, migraine, schizophrenia, alcoholism and affective disorders, etc. In the epilepsy, it was reported that the cerebral blood flow was increased during ictal phase, but decreased during interictal period, while others insisted of interictal hyperperfusion due to subictal neuronal hyperactivity. We compared the cerebral blood flow of 17 epileptics with that of 12 neurotic controls measured by 99m Tc-HMPAO SPECT to observe the perfusion change in the interictal phase. The results were as follows : 1) Compared to the controls whose activity counts per frame were decreased to 5.5 ±3.3%(mean ±S.D.), 29.4% of epileptics showed hyperperfusion to 10.9±7.2%(p<0.05), and 70.6% showed hypoperfusion to 10.8±3.3%(p<0.001). 2) Most of foci of maximal blood flow change were located at the right hemisphere and posterior part. The foci in the anterior part could be found more in controls(33.3%), while posterior foci in epileptics(88.2% ;hyperperfusion group 80.8%, hyoperfusion group 91.6%) without statistical significance. 3) The degree of EEG abnormality was not correlated whit the activity counts per frame. Abnormal findings were more frequently seen in the hyperperfusion gruop(80.8%) than in the hypoperfusion group(41.7%) without statistical significance. The abnormal findings are mostly composed of high voltage(88.9%), and spike with or without wave(50.0%) or slow wave only(50.0%) without correlation with the activity counts per frame.

반복치료로 호전된 호산구성 폐렴 유사 폐흡충증 1예

박세진,김희규,김봉준,이천우,옥철호,정만홍 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.2

우리나라에서 인기 있는 게장등의 섭취로2) 성인뿐만 아니라 소아에서도 지속적으로 보고되고 있는 폐흡충증은 다양한 임상양상을 보일 수 있다. 저자들은 방사선 소견상 만성 호산구성 폐렴과 유사하였고, 반복적인 치료로 호전된 폐흡충증 1예를 경험하였기에 보고하는 바이다. Paragonimiasis mostly occurs by ingestion of raw or undercooked freshwater crabs or crayfish. Recently, re-emergence of paragonimiasis is reported because of ingestion of raw food such as freshwater fish and Gejang (marinated raw crabs). As the radiological features as well as the laboratory findings are similar to those of chronic eosinophilic pneumonia, the diagnosis of pulmonary paragonimiasis is often difficult and delayed. A 43 year-old female was visited our hospital for migrating and new developing consolidative lung lesions and peripheral blood eosinophilia. The eosinophil profile of leukocyte was 32% (absolute count 2,690 /mm3). Histologic finding was organizing pneumonia pattern with severe infiltration of eosinophils. Parasite specific antibody IgG forParagonimus westermani was positive (titer:0.61, normal range<0.20). After treatment with praziquantel (75mg/Kg once a day for 2days), the chest x-ray was clearly resolved. Follow-up study showed right pleural effusion, newly developed focal infiltration, and several nodules. After retreatment, we couldn't find any recurrent evidence.

강원도 함백폐탄광지역에서 생성되는 광산배수의 수질 특성

박천영,정연중,김성구,조갑진 조선대학교 에너지.자원신기술연구소 2001 에너지·자원신기술연구소 논문지 Vol.23 No.2

This study investigated geochemical characteristics of the mine drainage discharged from the abandoned coal mine in the Hamback area. Sampling of stream waters(21) were carried out in the Hamback area. The pH, EC, TDS, Eh and Do contents were measured in field and ions such as Na, K, Mg, Ca, Mn. Fe, S r , Al. Cr, Cu. Zn, Ge, As, Mo, Cd, Sb, Ba, Pb, F, Cl. No₃ and SO₄ were analyzed by GFAAS, AAS, ICP-AES, ICP-MS and IC. In stream waters, pH values increased, whereas total dissolved solids(TDS), electrical conductivity(EC) and dissolved oxygen(D0) values decreased with distance. Eh negative values a t upstream site were found, suggesting that its caused by the organic material in the retention pond, and these value in stream water effluent from the retention pond increased progressively with distance. The concentration of toxic heavy metals and major cations except Na, Cl, No₃, Cu, Mo and Sb decreased rapidly due to retention pond, but the concentration of Na, Cl, No₃, Cu, Mo and Sb increased gradually with distance. The concentration of Na, Cl and No₃ increasing with distance, which indicate by domestic waste. Major ions, such as Na, K, Ca, Mg, F, Cl, SO₄ and HCO₃ were statically analyzed in order to investigate relationship with TDS contents. M is observed that TDS contents have-positive relation with K, Ca, Mg, F, so4 and HC0₃ contents, but negative relationships with Na, Cl and No₃ contents. Most stream surface waters showed a calcium-sulfate and noncarbonate hardness dominating water quality type. In geochemical modeling for stream surface waters, the saturation index of gibbsite were oversaturated with respect to gibbsite.

우수 사과酒酵母의 分離와 利用에 關한 硏究

朴允仲,金燦祚,李錫健,吳萬鎭,孫天培 충남대학교 농업과학연구소 1978 農業技術硏究報告 Vol.5 No.1

Extensive selection works on wild yeasts of fruits were carried cut to obtain strains which are applicable to apple wine making. Among the total number of 1,358 yeast strains which were isolated from various fruit samples collected from the vicinity of Daejeon and other regions of Korea, the strains SH-49, SH-129 and SH-338 were found to be useful. Then experiments on their morphological and physiological characteristics, and on the aspects of practical use in apple wine making were proceeded. The results obtained were as follows: 1. The strains SH-49 and SH-129, particularly SH-49, were appeared to have good fermentation ability, tolerance to sulfur dioxide and to produce fine quality of apple wine. 2. Apple wines made by using the strain, SH-49 and SH-129 contained less amount of total acids than those by other strains. 3. Apple wines of SH-49 and SH-129 were clarified rapidly during the primary fermentation period, and their absorbancy at 430 nm after 45 days of storage were approximately half of others. 4. Apple wine of SH-338 contained higher amount of residual sugar and its quality was superior to others. It is considered that this strain could be used in the production of apple wine of a characteristic quality. 5. The strains SH-49 and SH-338 were identified as a Saccharomyces cerevisiae according to Taxanomic Study of Yeasts by Lodder, however, classification of SH-129 was suspended for further study.

甚한 惡液質을 同伴한 若年性 進行痲痺 (晩發性 先天梅毒) 1例

田珍淑,朴容九 大韓神經精神醫學會 1988 신경정신의학 Vol.27 No.4

A 15 year-old boy, who had been ill in bed with pervasive cognitive impairment, poor intelligence, global aphasia, disuse muscular atropy, etc since the age of 11 years is reported under the impression of juvenile general paresis. His mother and an elder brother also had positive responses to serologic tests for syphilis. Brain computed tomography showed marked dilatation of ventricles without sulcal enlargement, which was interpreted as communicating hydrocephalus rather than cerebral atropy. He showed some improvements of intelligence and cognitive functions after intramuscular penicillin administration and ventriculoperitoneal shunt. However, it was not good enough to say that his daily living activities in general had improved.

정신분열병 환자에서의 뇌위축

전진숙,박용구 大韓神經精神醫學會 1988 신경정신의학 Vol.27 No.4

Cerebral and cerebellar atrophic changes on computerized tomography (CT) scans of 18 schizophrenics and 25 age-matched controls were reviewed. Sizes of variable portions of ventricles and several cisterns was measured and presence of abnormal widenings of several subarachnoid cisterns was investigated on CT scans. The prevalences of both cerebral and cerebellar atrophy were significantly higher(p=0.001, p=0.001) in the schizophrenics than the controls. However, all of the atrophic changes were questionable or mild except two cases in each supratentorial and infratentorial structures. The cerebral and cerebellar atrophic changes had statistically significant positive linear correlation. The mean symptom duration was significantly longer in the undifferentiated type than the paranoid type (p=0.007), in the cases with negative symptom than with positive symptom(p=0.03). Negative symptoms were more in the undifferentiated type. These findings were consistent with previous reports that correlate the cerebral and cerebellar atrophies with schizophrenia and these results suggest that the brain atrophy in schizophrenics is not an isolated event but a feature of diffuse brain atrophy.

鋼管多段 Grouting 工法의 Tunnel 補强效果에 關한 硏究

박진원,류체천,김송만,박춘수 충남대학교 산업기술연구소 2001 산업기술연구논문집 Vol.16 No.1

When Umbrella Arch Method is applied in construction of the first Ok-chon tunnel which have soft ground zone or fractured zone, the result as finite element analysis method, the PENTAGON-2D, is following. 1)There is little effect in bottom displacement due to side wall reinforcement, but side wall displacement decrease 50%. 2)Before reinforced by Umbrella Arch Method, rockbolt axial stress is 16 ton which exceed allowed axial stress, however after reinforced, that is about 5.5ton in up and down path, therefore rockbolt axial stress after reinforced is safe. 3)In shotcrete, compression stress decrease average 65% and shearing force and bending moment is decrease more than average 65%. hence shotcrete has great effect on ground reinforcement in side wall. 4)Umbrella Arch Method was proven as assistant method in fractured zone, but in long term stability, judging the fact that bottom displacement is slightly great, the tunnel invert is continued. Or bottom must be reinforced with reinforced with reference to field measurement data in excavation.