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      • 대학생 자녀를 둔 중년여성의 자아존중감, 자녀와의 관계, SNS 이용강도가 우울에 미치는 영향

        우지원,김가은,김경미,남주희,박지인,범준희,이나경,조소연,조은경,최영윤,김석선,길민지 이화여자대학교 간호과학대학 2017 이화간호학회지 Vol.- No.51

        Purpose: This study aims to identify the effects of self-esteem, relationship with children, Social Networking Services(SNS) use intensity on depression in middle-aged women with college-age children, and to provide basic data for the health promotion of middle-aged women. Method: A sample of 133 middle-aged people was purposely selected from parents of university students. Questionnaires used for this study were CES-D(The Center for Epidemiological Studies-Depression Scale), Self-esteem Scale, Relationship with Children Scale, SNS Intensity Scale. The collected data was analyzed by SPSS 21 with descriptive statistics, independent t-test, ANOVAs, Pearson correlation, multiple regression. Result: Self-esteem was correlated with relationship with children (r=0.385, p<0.01) and depression (r=-0.440, p<0.01). Relationship with children was correlated with depression(r=-0.402, p<0.01). As a result, a factor having the greatest influence on the subject's depression degree was self-esteem(β=-0.335), followed by relationship with children(β=-0.274). Conclusion: The result of this study suggested that depression in middle-aged women is closely related to self-esteem and relationship with children. This result can be used in Nursing by developing the theoretical basis for education program related to enhancing self-esteem and relationship with children.

      • SCOPUSKCI등재

        포상기태와 융모상피암 환자의 갑상선기능

        박기현,김현만,허갑범,이현철,김경래,김한수,김주항,김세광 대한내분비학회 1988 Endocrinology and metabolism Vol.3 No.1

        It has been recognized that hyperthyroidism occur in patients with trophoblastic disease, either hydatidiform moles or choriocarcinomas. In the past decade, several lines of evidence have shown that human chorionic gonadotropin, secreted by the trophoblastic disease, is a thyroid stimulator and causes hyperthyroidism. In order to evaluate the relationship between level of thyroid hormone and human chorionic gonadotropin in patients with trophoblastic disease, level of thyroid hormone, serum -HCG and amount of urinary excretion of HCG were measured and analyzed in 24 patients with hydatidiform mole and 11 patients with choriocarcinoma who were admitted to Yonsei University Severance Hospital during the period from January 1981 to December 1986. The results are summarzed as follows: 1) Hyperthyroidism was observed in 33.3% of the patients with hydatidiform mole and in 18.2% of the patients with choriocarcinoma. 2) The amount of 24 hour urinary excretion of HCG in patients with hyperthyroidism was more than that in euthroid patients. 3) There was no difference in the level of thyroid hormone, serum -HCG, and amount of 24 hour urinary excretion of HCG in patients with hydatidifrom mole and choriocarcinoma. 4) The amount of 24 hour urinary excretion of HCG had significant correlation with FT4, whereas no similar correlation was observed between the levels of thyroid hormone and serum -HCG. In conclusion, the occurrence of hyperthyroidism is closely related with the amount of urinary excretion of HCG in patients with trophblastic disease.

      • SCISCIESCOPUSKCI등재
      • Altman's Z-score and Option-based Approach for Credit Risk Measure(Bankruptcy Prediction : Book value or Market Value?)

        BUM J. KIM 한국재무학회 2007 한국재무학회 학술대회 Vol.2007 No.04

        Managers, stockholders, lenders and employees concern about their firm’s financial condition. This shared interest creates continual inquiries and recurrent attempt to answer the incessant question about how we predict financial distress or what reveals the credit risk of firms. Despite numerous attempts for bankruptcy prediction and their application over three decades after Altman (1968)’s seminal study, financial distress prediction research has not seemed to reach an unequivocal conclusion. We investigated our postulations concerning Altman’s Z-score and the option-based measure based on arguments that the Z-score should lose its significance since its introduction due to some reasons. Based on our results, we learned that Altman’s Z-score loses its significance as a bankruptcy prediction measure due to two possible grounds; it loses its prediction power for long-term prediction and it was not significance for recent years’ data. In addition, we found that the option-based measure does provide significant results as a prediction measure for later years. We believe that the reduction of prediction time span of Z-score and better performance of the option-based measure implies that the more efficient market shortens the information transition time in the market so that bankruptcy prediction should be based on immediate and continuously changing information about the event and discrete or sporadic variables would mislay the interpretation of information concerning bankruptcy.

      • KCI등재
      • SCISCIESCOPUS

        IL-33–Induced Hematopoietic Stem and Progenitor Cell Mobilization Depends upon CCR2

        Kim, Juyang,Kim, Wonyoung,Le, Hongnga T.,Moon, U J.,Tran, Vuvi G.,Kim, Hyun J.,Jung, Soyeon,Nguyen, Quang-Tam,Kim, Byung-Sam,Jun, Jae-Bum,Cho, Hong R.,Kwon, Byungsuk American Association of Immunologists 2014 Journal of Immunology Vol. No.

        <P>IL-33 has been implicated in the pathogenesis of asthma, atopic allergy, anaphylaxis, and other inflammatory diseases by promoting the production of proinflammatory cytokines and chemokines or Th2 immune responses. In this study, we analyzed the in vivo effect of IL-33 administration. IL-33 markedly promoted myelopoiesis in the bone marrow and myeloid cell emigration. Concomitantly, IL-33 induced hematopoietic stem and progenitor cell (HSPC) mobilization and extramedullary hematopoiesis. HSPC mobilization was mediated mainly through increased levels of CCL7 produced by vascular endothelial cells in response to IL-33. In vivo treatment of IL-33 rapidly induced phosphorylation of ERK, JNK, and p38, and inhibition of these signaling molecules completely blocked the production of CCL7 induced by IL-33. Consistently, inhibitor of CCR2 markedly reduced IL-33–mediated HSPC mobilization in vivo and migration of HSPCs in response to CCL7 in vitro. IL-33–mobilized HSPCs were capable of homing to, and of long-term reconstitution in, the bone marrow of irradiated recipients. Immune cells derived from these recipients had normal antifungal activity. The ability of IL-33 to promote migration of HSPCs and myeloid cells into the periphery and to regulate their antifungal activity represents a previously unrecognized role of IL-33 in innate immunity. These properties of IL-33 have clinical implications in hematopoietic stem cell transplantation.</P>

      • Future ozone and oxidants change under the RCP scenarios

        Kim, Minjoong J.,Park, Rokjin J.,Ho, Chang-Hoi,Woo, Jung-Hun,Choi, Ki-Chul,Song, Chang-Keun,Lee, Jae-Bum Elsevier 2015 Atmospheric environment Vol.101 No.-

        <P><B>Abstract</B></P> <P>We investigate ozone air quality changes in 2050 caused by global changes in climate and anthropogenic emissions of ozone precursors by using a global chemical transport model driven by meteorological fields from a general circulation model. We use projected emissions based on the Representative Concentration Pathway (RCP) scenarios and conduct model simulations to quantify the effects of climate and emission changes on future air quality, focusing on ozone in surface air. Our model results show that annual mean concentrations of surface ozone will be lower in 2050 relative to 2000 by −3.3, −3.7, and −4.2 ppbv under RCP6.0, RCP4.5, and RCP2.6, respectively. In contrast, the RCP8.5 projection results in a slight increase of 2.1 ppbv caused by a methane increase. The ozone reductions are driven primarily by decreases in NO<SUB>x</SUB> emission, which dominate the climate penalty on ozone driven by temperature increases. We also estimate the effect of 21st century climate change on ozone air quality, assuming no changes in anthropogenic emissions of ozone precursors in the future. We further use a statistical method to analyze the results in order to quantify the effect of each meteorological variable change on ozone concentration in summer. Temperature increase is found to result in ozone increases of up to 2.2 ppbv over land. Ozone over the oceans, however, is largely reduced with specific humidity increase, particularly in the Northern Hemisphere, where the ozone concentration decreases by 0.8 ppbv. We find that future increases in natural NO<SUB>x</SUB> emissions from lightning and soil make an important contribution to the formation of nitric acid and might seriously offset future decreases in nitrogen deposition caused by anthropogenic NO<SUB>x</SUB> emission reduction.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We developed a new linking tool between GEOS-Chem and CESM. </LI> <LI> We investigate ozone air quality changes in 2050 relative to 2000. </LI> <LI> Annual surface ozone changes in 2050 are −4.2–+2.1 ppbv under RCP scenarios. </LI> <LI> Natural NO<SUB>x</SUB> emissions might seriously affect future nitrogen deposition. </LI> </UL> </P>

      • Economic Costs for Adult Asthmatics According to Severity and Control Status in Korean Tertiary Hospitals

        Kim, Sae-Hoon,Kim, Tae-Wan,Kwon, Jae-Woo,Kang, Hye-Ryun,Lee, Yong-Won,Kim, Tae-Bum,Kim, Sang-Heon,Park, Heung-Woo,Park, Sung-Woo,Chang, Yoon-Seok,Cho, You-Sook,Park, Jung-Won,Cho, Young-Joo,Yoon, Ho-J Informa Healthcare 2012 The Journal of asthma Vol.49 No.3

        <P><I>Objective</I>. The prevalence of asthma is increasing, and asthma causes considerable socioeconomic burden worldwide. Few studies have been conducted to evaluate the risk factors associated with economic cost of asthma in Korea. This study evaluated asthma cost according to severity, control, and patient factors in Korean tertiary hospitals. <I>Methods</I>. Direct and indirect costs were assessed in physician-diagnosed adult asthmatics recruited from eight tertiary hospitals in Korea. Official direct medical costs were derived from the analysis of 1-year expenditures related to hospital care utilization and asthma medication. Nonofficial medical costs, nonmedical direct costs, and indirect costs were investigated using a questionnaire designed specifically for the study. <I>Results</I>. A total of 314 patients with persistent asthma were recruited. Both direct and indirect costs were significantly higher for patients with severe persistent asthma than for those with mild and moderate persistent asthma ($2214 vs. $871 and $978, <I>p</I> < .001; $2927 vs. $490 and $443, <I>p</I> < .001, respectively). Costs of asthma increased significantly in poorly controlled compared with somewhat controlled and well-controlled asthma ($7009.8 vs. $2725.3 vs. $1517.3, respectively; <I>p</I> < .001). After stratification for severity, a significant cost increase in the poorly controlled asthma group was observed only for indirect costs and not for direct costs. A multivariate analysis showed that female gender was a risk factor for increased indirect costs. <I>Conclusion.</I> The burden of asthma was higher both for patients with severe persistent asthma and for patients with poorly controlled asthma. More effective strategies are needed to improve control status, particularly targeting patients with severe asthma.</P>

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