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      • KCI등재

        Numerical solution for multiple confocal elliptic dissimilar cylinders

        Y. Z. Chen 국제구조공학회 2017 Smart Structures and Systems, An International Jou Vol.19 No.2

        This paper provides a numerical solution for multiple confocal elliptic dissimilar cylinders. In the problem, the inner elliptic notch is under the traction free condition. The medium is composed of many confocal elliptic dissimilar cylinders. The transfer matrix method is used to study the continuity condition for the stress and displacement along the interfaces. Two cases, or the infinite matrix case and the finite matrix case, are studied in this paper. In the former case, the remote tension is applied in y- direction. In the latter case, the normal loading is applied along the exterior elliptic contour. For two cases, several numerical results are provided.

      • KCI등재

        R&D Status of High-current Accelerators at IFP

        J. J. Deng,J. S. Shi,W. P. Xie,L. W. Zhang,K. Z. Zhang,S. P. Feng,J. Li,M. Wang,Y. He,L. S. Xia,Z. Y. Dai,H. T. Li,L. Wen,S. F. Chen,X. Li,Q. G. Lai,M. H. Xia,Y. C. Guan,S. Y. Song,L. Chen 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.61

        High-current accelerators have many important applications in Z-pinches, high-power microwaves, and free electron lasers, imploding liners and radiography and so on. Research activities on Zpinches, imploding liners, radiography at the Institute of Fluid Physics (IFP) are introduced. Several main high-current accelerators developed and being developed at IFP are described, such as the Linear Induction Accelerator X-Ray Facility Upgrade (LIAXFU, 12 MeV, 2.5 kA, 90 ns), the Dragon-I linear induction accelerator (20 MeV, 2.5 kA, 60 ns), and the Primary Test Stand for Z-pinch (PTS, 10 MA, 120 ns). The design of Dragon-II linear induction accelerator (20 MeV, 2.5 kA, 3 × 60 ns) to be built will be presented briefly.

      • A Phase 3 Evaluation of Daclatasvir plus Asunaprevir in Treatment-Naive Patients with Chronic HCV Genotype 1b Infection

        ( L. Wei ),( F. Wang ),( M. Zhang ),( J. Jia ),( A.A. Yakovlev ),( W. Xie ),( E.Z. Burnevich ),( J. Niu ),( Y.J. Jung ),( X. Jiang ),( M. Xu ),( X. Chen ),( Q. Xie ),( J. Li ),( J. Hou ),( H. Tang ),( 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

        Background/Aims: Treatment-naive GT 1b-infected patients from mainland China, South Korea and Russia were assessed for SVR at follow-up week 12 (SVR12) after receiving daclatasvir (60 mg, QD) and asunaprevir (100 mg, BID) (DCV+ASV). Methods: Patients were randomized 3:1 to receive DCV+ASV (24 weeks; immediate treatment [IM]) or 12 weeks of placebo followed by DCV+ASV (24 weeks; placebo-deferred treatment [PD]). The primary endpoint was to evaluate SVR12 in the IM arm to the historical rate for peginterferon/ribavirin (70%). Secondary endpoints included overall safety and safety comparisons between the treatment arms during the first 12 weeks. Results: 207 patients were randomized to IM (n=155) or PD (n=52); Asian (86%), female (59%), IL28B CC genotype (68%) and median age 49 (range 18-73) years; cirrhosis (13%), HCV RNA ≥6x106 IU/mL (53%). SVR12 in the IM arm was 92% and broadly unaffected by most baseline factors assessed (Figure); SVR12 was higher in patients without (96%) baseline NS5A-L31M/V or Y93H polymorphisms. There were 6 virologic breakthroughs, 6 relapses and 1 detectable HCV RNA at end-of-treatment in the IM arm. Safety was mostly comparable between the two arms during the first 12 weeks. The most frequent adverse events (AEs; ≥5%) during DCV+ASV (24 weeks) treatment in both arms were aminotransferase, bilirubin and INR elevations, hypertension, fatigue and respiratory tract infections; the most frequent treatment-emergent grade 3/4 laboratory abnormalities were aminotransferase (≤4.5%) and hematologic, lipase and total bilirubin abnormalities (≤2%); one patient (IM) discontinued DCV+ASV for aminotransferase elevations, nausea and jaundice (all reversible); one patient PD) discontinued DCV+ASV for a fatal AE unrelated to treatment. Conclusions: These data demonstrate that DCV+ASV is a highly efficacious and well tolerated treatment for treatment-naive HCV GT 1b-infected patients. Those treated immediately with DCV+ASV achieved a 92% SVR12 rate which was unaffected by factors known to attenuate response to interferon.

      • SCIESCOPUSKCI등재

        True Digestibility of Phosphorus in Different Resources of Feed Ingredients in Growing Pigs

        Wu, X.,Ruan, Z.,Zhang, Y.G.,Hou, Y.Q.,Yin, Y.L.,Li, T.J.,Huang, R.L.,Chu, W.Y.,Kong, X.F.,Gao, B.,Chen, L.X. Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.1

        To determine the true digestible phosphorus (TDP) requirement of growing pigs, two experiments were designed with the experimental diets containing five true digestible P levels (0.16%, 0.20%, 0.23%, 0.26% and 0.39%) and the ratio of total calcium to true digestible P (TDP) kept at 2:1. In Experiment 1, five barrows (Duroc${\times}$Landrace${\times}$Yorkshire) with an average initial body weight of 27.9 kg were used in a $5{\times}5$ Latin-square design to evaluate the effect of different dietary P levels on the digestibility and output of P and nitrogen. In Experiment 2, sixty healthy growing pigs (Duroc${\times}$Landrace${\times}$Yorkshire) with an average body weight (BW) of 21.4 kg were assigned randomly to one of the five dietary treatments (12 pigs/diet), and were used to determine the true digestible phosphorus (TDP) requirement of growing pigs on the basis of growth performance and serum biochemical indices. The results indicated that the true digestibility of P increased (p<0.05) linearly with increasing dietary TDP level below 0.26%. The true P digestibility was highest (56.6%) when dietary TDP was 0.34%. Expressed as g/kg dry matter intake (DMI), fecal P output increased (p<0.05) linearly with increasing P input. On the basis of g/kg fecal dry matter (DM), fecal P output was lowest for Diet 4 and highest (p<0.05) for Diet 5. The apparent digestibility of crude protein (CP) did not differ (p>0.05) among the five diets, with the average nitrogen output of 12.14 g/d and nitrogen retention of 66% to 74% (p>0.05), which suggested that there was no interaction between dietary P and CP protein levels. During the 28-d experimental period of Experiment 2, the average daily gain (ADG) of pigs was affected by dietary TDP levels as described by Eq. (1): $y=-809,532x^4+788,079x^3-276,250x^2+42,114x-1,759$; ($R^2=0.99$; p<0.01; y = ADG, g/d; x = dietary TDP, %), F/G for pigs by Eq. (2): $y=3,651.1x^4-3,480.4x^3+1,183.8x^2-172.5x+10.9$ ($R^2=0.99$; p<0.01; y = F/G; x = dietary TDP, %), and Total P concentrations in serum by Eq. (3): $y=-3,311.7x^4+3,342.7x^3-1,224.6x^2+195.6x-8.7$ (R2 = 0.99; p<0.01; y = total serum P concentration and x = dietary TDP, %). The highest ADG (782 g/d), the lowest F/G (1.07) and the highest total serum P concentration (3.1 mmol/L) were obtained when dietary TDP level was 0.34%. Collectively, these results indicate that the optimal TDP requirement of growing pigs is 0.34% of the diet at a total Ca to TDP ratio of 2:1.

      • Composite components damage tracking and dynamic structural behaviour with AI algorithm

        Z.Y. Chen,Sheng-Hsiang Peng,Yahui Meng,Ruei-Yuan Wang,Qiuli Fu,Timothy Chen 국제구조공학회 2022 Steel and Composite Structures, An International J Vol.42 No.2

        This study discusses a hypothetical method for tracking the propagation damage of Carbon Reinforced Fiber Plastic (CRFP) components underneath vibration fatigue. The High Cycle Fatigue (HCF) behavior of composite materials was generally not as severe as this of admixture alloys. Each fissure initiation in metal alloys may quickly lead to the opposite. The HCF behavior of composite materials is usually an extended state of continuous degradation between resin and fibers. The increase is that any layer-to-layer contact conditions during delamination opening will cause a dynamic complex response, which may be non-linear and dependent on temperature. Usually resulted from major deformations, it could be properly surveyed by a non-contact investigation system. Here, this article discusses the scanning laser application of that vibrometer to track the propagation damage of CRFP components underneath fatigue vibration loading. Thus, the study purpose is to demonstrate that the investigation method can implement systematically a series of hypothetical means and dynamic characteristics. The application of the relaxation method based on numerical simulation in the Artificial Intelligence (AI) Evolved Bat (EB) strategy to reduce the dynamic response is proved by numerical simulation. Thermal imaging cameras are also measurement parts of the chain and provide information in qualitative about the temperature location of the evolution and hot spots of damage.

      • Solution for null field CVBIE in plane elasticity using an accurate shape function

        Chen, Y.Z. Techno-Press 2021 Advances in computational design Vol.6 No.2

        This paper provides a numerical solution for null field complex variable boundary integral equation (CVBIE) in plane elasticity. All kernels in the null field CVBIE are regular function. An accurate shape function for the displacement and traction along the contour is suggested. With the usage of suggested shape function, a discretization for the boundary integral equation (BIE) is carried out. The Dirichlet and the Neumann boundary value problems (BVPs) for the interior region and the exterior region are studied. Two numerical examples are provided in the paper. It is shown that a higher accuracy has been achieved in the examples with the usage of the suggested shape function.

      • SCIESCOPUS

        Transfer matrix method for solution of FGMs thick-walled cylinder with arbitrary inhomogeneous elastic response

        Chen, Y.Z. Techno-Press 2018 Smart Structures and Systems, An International Jou Vol.21 No.4

        This paper presents a numerical solution for the thick cylinders made of functionally graded materials (FGMs) with a constant Poisson's ratio and an arbitrary Young's modulus. We define two fundamental solutions which are derived from an ordinary differential equation under two particular initial boundary conditions. In addition, for the single layer case, we can define the transfer matrix N. The matrix gives a relation between the values of stress and displacement at the interior and exterior points. By using the assumed boundary condition and the transfer matrix, we can obtain the final solution. The transfer matrix method also provides an effective way for the solution of multiply layered cylinder. Finally, a lot of numerical examples are present.

      • KCI등재후보

        Smart structural control and analysis for earthquake excited building with evolutionary design

        Z.Y. Chen,Ruei-yuan Wang,Yahui Meng,Qiuli Fu,Timothy Chen 국제구조공학회 2021 Structural Engineering and Mechanics, An Int'l Jou Vol.79 No.2

        In recent years, with the maximization of control design and efficiency, and the improvement of economy and energy efficiency, building technology and control in the theory have attracted the attention of lots researchers. By trying various control theorems, many numerical methods have been investigated in the literature to achieve this target, but all these numerical methods are difficult to work out the problem correctly. This paper puts forward a potentially feasible evolutionary bat algorithm (EB) method for active control of earthquake-induced vibration in building structures. Based disturbance observer based control and S surface combined with the robust adaptive control scheme for solving optimization problems proposed, an important contribution in the control law is what the configuration control in the present study should not require known uncertainty limits and the disturbance is eliminated. A simulation case study was proposed to illustrate the possibility of implementing an apparent learning method in ANN to effectively control structural vibration under the influence of systematic motion under earthquake citations. The proposed learning numerical methods does not need to develop a mathematical model of structural dynamics or train another neural network to approximate the actual structural response to be performed.

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