Analysis of Listing by Buying Shell in China

Shuang jun Xu,Hyun-rae, Cho 大田大學校 社會科學硏究所 2020 社會科學論文集 Vol.- No.-

Under the background of strict conditions and strict review procedures for IPO application, some enterprises find another way to obtain listing qualification by buying shell, and then achieve the purpose of raising funds, and promote the long-term development of enterprises. But the process has not been smooth. Therefore,this paper introduces the status of shell listing activities in the Chinese market from the perspectives of otivations, valuation calculation and risks of shell listing,which provides successful experience for other enterprises to successfully complete the merger and acquisition of shell buying listing, and also provides scientific decision-making.It also provides scientific decision-making and reference for investors to rationally investigate the future returns of buying shells for listing.

Harmonic Analysis of SPWM Wave for Single - Phase Bridge Inverter

Shuang Xu,Ling Pang,Jinghua Zhou,Liuchen Chang 전력전자학회 2023 ICPE(ISPE)논문집 Vol.2023 No.-

Two-level single-phase bridge inverters are widely used in distributed energy systems due to its topological symmetry and ease of modulation. The harmonic contents of modulated output waves are critical performance index in quantitatively determining the superiority or inferiority of a modulation strategy and in optimizing the modulation and filter parameters. For past decades, harmonic analyses on sinusoidal pulse width modulated (SPWM) waves of single-phase bridge inverters are mostly based on the double Fourier series representation, which is on the premise that SPWM wave is a two-dimensional periodic function of two variables with different frequencies. However, this premise is more tenable for pulse amplitude modulation (PAM) than for SPWM, since PAM is the product of a line-frequency sine wave and a carrier-frequency rectangular wave, whereas SPWM wave is the compared result of a line-frequency sine wave and a carrier-frequency triangular wave. This paper studies the double Fourier series representation of SPWM wave from double Fourier integral essence, develops a harmonic analysis method for SPWM wave with the aid of fast Fourier transform (FFT), correlates the harmonic spectra of PAM and SPWM, and finally, further analyzes the feasibility of double Fourier series on SPWM wave.

A Review of Researches on Emotional Labor and Its Causality Model Construction

Shuang jun Xu,Park, Kyehong 大田大學校 社會科學硏究所 2022 社會科學論文集 Vol.- No.-

Emotional labor is playing an increasingly important role in contemporary organization management, especially in the service industry. Emotional labor of employees will have various effects to the organization. Based on the literature on emotional labor at home and abroad, this article analyzed the concept of emotional labor from different perspectives, sorted out the dimensions of emotional labor, discussed its antecedent variables and outcome variables from the theory of emotional labor, clarified the construction of the causality model of emotional labor, and finally helped human resource management in the enterpris

Development of High-specificity Antibodies against Renal Urate Transporters Using Genetic Immunization

( Guo Shuang Xu ),( Xiang Mei Chen ),( Di Wu ),( Suo Zhu Shi ),( Jian Zhong Wang ),( Rui Ding ),( Quan Hong ),( Zhe Feng ),( Shu Peng Lin ),( Yang Lu ) 생화학분자생물학회 2006 BMB Reports Vol.39 No.6

QTL Analysis for Low-Temperature Requirement Vernalization in Brassica campestris

Yang Xu,Yu Yang Jun,Zhang Feng Lan,Zhao Xiu Yun,Zhang De Shuang,Xu Jia Bing 한국원예학회 2006 한국원예학회 기타간행물 Vol.- No.-

Molecular characterization and functional analysis of two trehalose transporter genes in the cabbage beetle, Colaphellus bowringi

Li Jia-Xu,Cao Zhen,Guo Shuang,Tian Zhong,Liu Wen,Zhu Fen,Wang Xiao-Ping 한국응용곤충학회 2020 Journal of Asia-Pacific Entomology Vol.23 No.3

The trehalose, major blood sugar in insects, enhances stress resistance of diapausing individuals in adverse environment and provides an energy source for reproduction. Trehalose transporters (TRETs) play an important role in transport of trehalose from trehalose-producing tissues, e.g. fat body, to trehalose-consuming tissues. Although studies have shown that trehalose contributes to diapause and reproduction, the function of TRETs in these processes remains unclear. In this work, we cloned two TRET genes, TRET1a and TRET1b, from the cabbage beetle Colaphellus bowringi, which is capable of entering reproductive diapause under long-day conditions. We also analyzed the expression profiles of these two genes and investigated their potential roles in diapause and reproduction. The results suggested that both TRET1a and TRET1b belong to sugar-transporter and major facilitator superfamilies. Interestingly, TRET1a was highly expressed in the fat bodies of diapause-destined (DD) females but TRET1b was predominantly expressed in the ovaries of non-diapause-destined (NDD) females. Hormonal induction indicated that juvenile hormone induced TRET1b but repressed TRET1a at transcriptional levels. Methoprene-tolerant and Krüppel homolog 1 mediated the JH-suppressed TRET1a expression but were not involved in the regulation of TRET1b expression by JH. RNAi of TRET1a in DD females elevated the trehalose content in the fat bodies and suppressed the expression of a couple of genes related to stress resistance, which is a critical diapause trait. Knockdown of TRET1b in NDD females reduced the trehalose content in the ovaries but had no apparent effect on the ovary development and yolk deposition. These data suggest that TRET1a and TRET1b could regulate the trehalose content in specific tissues and may play potential roles in reproductive diapause in the females of C. bowringi. Introduction Diapause is a survival strategy for many insects in adapting to adverse environmental conditions (Tauber and Tauber, 1976; Tougeron, 2019). Diapause is a dynamic successive process that consists of diapause induction, preparation, initiation, maintenance, termination, and post-diapause quiescence (Kostal, 2006). Insects accumulate enormous nutrients such as sugars and lipids to enter diapause during diapause preparation phase (Hahn and Denlinger, 2007, 2011). The trehalose is the major hemolymph sugar in insects. The sugar not only provides source of energy but also protects proteins and cellular membranes from dehydration, desiccation, heat, cold, and oxidation (Elbein et al., 2003; Li et al., 2002; Richards et al., 2002; Wyatt and Kalf, 1957; Yancey, 2005; Zhu et al., 2008). Therefore, trehalose can play roles in reproduction and diapause by mediating energy supply and stress tolerance, respectively (Kamei et al., 2011; Lu et al., 2019; Xu et al., 2009).

Lasiokaurin derivatives: synthesis, antimicrobial and antitumor biological evaluation, and apoptosis-inducing effects

Da-Hong Li,Ping Hu,Sheng-tao Xu,Chun-yan Fang,Shuang Tang,Xin-yu Wang,Xing-yan Sun,He Lian,Ying Xu,Xiao-ke Gu,Jin-yi Xu 대한약학회 2017 Archives of Pharmacal Research Vol.40 No.7

Herein, a series of lasiokaurin derivatives were designed and synthesized. All the derivatives together with lasiokaurin and oridonin were tested for their antimicrobial and antiproliferative activity. Compound 16 showed the most promising antimicrobial activity with MICs of 2.0 and 1.0 lg/mL against Gram-Positive bacteria S. aureus and B. subtilis, respectively. All the synthetic lasiokaurin derivatives showed better antiproliferative activity than parent compound lasiokaurin 1. Compound 10 exhibited the strongest cytotoxicity with IC50 values of 0.47 and 0.20 lM against MGC-803 and CaEs-17 cells, accordingly. Moreover, it was shown to have potent antitumor activity in vivo in a murine model of MGC-803 gastric cancer. Preliminary SARs were also concluded based on obtained data. The apoptosis-inducing effects of 10 were further investigated using CaEs-17 cells. The results showed that lasiokaurin derivative 10 could induce apoptosis via mitochondria related pathway and arrest CaEs-17 cell cycle at S phase. Compound 10 could also affect apoptosisrelated proteins that was up-regulation of CDK2 and downregulation of ATM and cyclin A1.

Screening and Anti-virulent Study of N-Acyl Homoserine Lactones DNA Aptamers against Pseudomonas aeruginosa Quorum Sensing

Zu-Guo Zhao,Yun Mei Yu,Bi Yu Xu,Shuang-Shuang Yan,Jun-Fa Xu,Fang Liu,Guo-Ming Li,Yuan Lin Ding,Shu Qing Wu 한국생물공학회 2013 Biotechnology and Bioprocess Engineering Vol.18 No.2

In Pseudomonas aeruginosa, a quorum sensing (QS) system regulates the expression of many virulence factors. N-acyl homoserine lactone (HSL) is the signal molecule of QS system. In order to find a novel HSL binder to interfere with QS signaling and to attenuate P. aeruginosa virulence, an amino lactam surrogate (ALS) of HSL was used as a target to screen HSL aptamers with the technique of systematic evolution of ligands by exponential enrichment (SELEX). Eight HSL aptamers with high affinities for 3O-C12-HSL (20 nM ≤ Kd < 35 nM) or C4-HSL (25 nM < Kd < 50 nM) were finally obtained. In vitro QS-inhibiting study of P. aeruginosa showed that HSL aptamers could inhibit virulence in a dose-dependent manner. ALSap-8 which bound C4-HSL primarily acted on the rhl system and inhibited the secretion of pyocyanin. ALSap-5 which bound 3O-C12-HSL not only showed strong inhibitory activity on biofilm formation as well as secretions of LasA protease and LasB elastase, but also reduced pyocyanin secretion. Since the las system is capable of activating the rhl system mildly, we speculated that ALSap-5 can simultaneously interfere with the las and rhl systems. High-affinity aptamers against HSL in this study are novel QS and virulence-inhibitors, and may have potential as drug candidates for the treatment of P. aeruginosa infection.

Amino acid, fatty acid, and carbohydrate metabolomic profi les with ginsenoside-induced insecticidal effi cacy against Ostrinia furnacalis (Guenee)

Shuangli Liu,Xiaohui Wang,Rui Zhang,Mingjie Song,Nanqi Zhang,Wanying Li,Yingping Wang,Yonghua Xu,Lianxue Zhang 고려인삼학회 2020 Journal of Ginseng Research Vol.44 No.4

Background: Previous studies have shown the insecticidal efficacy of ginsenosides. In the present study,we aimed to investigate the metabolic mechanism related to the inhibitory effect of panaxadiol saponins(PDSs) against the Asian corn borer Ostrinia furnacalis (Guenee). Methods: Third instar larvae of O. furnacalis were fed normal diets with different concentrations of PDSsfor 4 days. The consumption index, relative growth rate, approximate digestibility, and conversion ofingested and digested food were recorded. A targeted gas chromatographyemass spectrometry assaywas performed to detect the profiles of amino acids, fatty acids, and carbohydrates in larvae ofO. furnacalis. In addition, the activity of detoxification-related enzymes was determined. Results and Conclusions: PDSs decreased the consumption index, relative growth rate, approximate digestibility,and conversion of ingested and digested food in the 3rd instar larvae of O. furnacalis in a dosedependentmanner. PDSs decreased 15 free amino acids, 16 free fatty acids, and 5 carbohydrates andincreased the levels of palmitoleic acid, palmitic acid, and 9-octadecenoic acid in the 3rd instar larvae. The activity of detoxification-related enzymes, such as acetylcholinesterase, glutathione S-transferase,cytochrome P450, carboxylesterase, trehalase, acid phosphatase, and alkaline phosphatase, was reducedin a dose-dependent manner in the 3rd instar larvae exposed to PDSs. These data confirmed theinhibitory effect of PDSs against growth, food utilization, and detoxification in the 3rd instar larvae ofO. furnacalis and the potential for using PDSs as an efficient tool for insect pest management forO. furnacalis larvae.

Abbreviated MRI Protocols for Detecting Breast Cancer in Women with Dense Breasts

Shuang-Qing Chen,Min Huang,Yu-Ying Shen,Chen-Lu Liu,Chuan-Xiao Xu 대한영상의학회 2017 Korean Journal of Radiology Vol.18 No.3

Objective: To evaluate the validity of two abbreviated protocols (AP) of MRI in breast cancer screening of dense breast tissue. Materials and Methods: This was a retrospective study in 356 participants with dense breast tissue and negative mammography results. The study was approved by the Nanjing Medical University Ethics Committee. Patients were imaged with a full diagnostic protocol (FDP) of MRI. Two APs (AP-1 consisting of the first post-contrast subtracted [FAST] and maximum-intensity projection [MIP] images, and AP-2 consisting of AP-1 combined with diffusion-weighted imaging [DWI]) and FDP images were analyzed separately, and the sensitivities and specificities of breast cancer detection were calculated. Results: Of the 356 women, 67 lesions were detected in 67 women (18.8%) by standard MR protocol, and histological examination revealed 14 malignant lesions and 53 benign lesions. The average interpretation time of AP-1 and AP-2 were 37 seconds and 54 seconds, respectively, while the average interpretation time of the FDP was 3 minutes and 25 seconds. The sensitivities of the AP-1, AP-2, and FDP were 92.9, 100, and 100%, respectively, and the specificities of the three MR protocols were 86.5, 95.0, and 96.8%, respectively. There was no significant difference among the three MR protocols in the diagnosis of breast cancer (p > 0.05). However, the specificity of AP-1 was significantly lower than that of AP-2 (p = 0.031) and FDP (p = 0.035), while there was no difference between AP-2 and FDP (p > 0.05). Conclusion: The AP may be efficient in the breast cancer screening of dense breast tissue. FAST and MIP images combined with DWI of MRI are helpful to improve the specificity of breast cancer detection.