급성 림프구성 백혈병 환자에서 아스페르길루스 감염을 동반한 호중구감소성 소장결장염에 의한 작은창자 천공

강동백,임태수,박원철,윤기중,이정균 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

저자들은 급성 림프구성 백혈병 치료 도중 아스페르길루스 감염을 동반한 호중구감소성 소장결장염에 의한 작은창자 천공을 경험하였다. 급성 림프구성 백혈병의 항암화학치료 중 발생 할 수 있는 호중구감소성 소장결장염은 다양한 위장관 증상을 보일 수 있으며, 이에 대한 발생 가능성을 고려하여 적극적인 조 기진단과 이에 대한 적극적 치료가 필요하며, 면역기능의 저하로 아스페르길루스 등의 진균 감염이 발생할 수 있으므로 호중구감소성 소장결장염의 치료에 증상의 호전이 없을 때 항진균제를 포함한 광범위한 치료가 고려되어야 한다. Though advancesin imumosuppressive therapy or chemotherapy which have lead to increased survival of leukemia and transplant patient, but the risk of infectious complication has been increasing. Neutropenic enterocolitis is a life threatening complication of chemotherapy for malignancies such as leukemia or lymphoma. Symptoms of neutropenic enterocolitis are nonspecific and it may rapidly lead to intestinal peforation. Aspergilus infection could involve the gastrointestinal tract as a result of neutropenia and mucosal injury after imumosuppressive therapy, chemoetherapy, or antibiotics use, but rarely reported a small bowel perforation combined aspergillus and neutropenic enterocolitis. We present a rare case of ileal perforation caused by neutropenic enterocolitis combined with aspergillus infection during chemotherapy for acute lymphocytic leukemia with a review of the literature.

都市街路의 遲滯度推定에 관한 硏究

임채문,권강훈,이주호,김태형 대구대학교 과학기술연구소 2001 科學技術硏究 Vol.8 No.1

This study suggested input variables whose effects have been considered by adjusting various input variables in the TRANSYT-7F and NETSIM, the Simulation programs employed in calculating the delay time at street sections. The results can be summarized as follow. 1. Among the input variables in the TRANSYT-7F needed to calculate the delay time at street sections, the excluded are those which effect the most on time delay, such as bus stops, pedestrian crossings and on/off ramps. Among the input variables the most affecting factors are Saturation flow rate and time delay whose suggested quotients are well summarized in the text of this study. 2. There are variables which affect the change of time delay in the NETSIM, such as bus stop, pedestrian crossing, bus appearance period, and departure time delay. This study did the Simulation program using those variables except pedestrian crossing because, as the result of the correlation analysis suggests, there is a strong correlation between bus stop and pedestrian crossing. In this study, the survey had been done in the morning and afternoon except the Peak time, so heavily congested sections were excluded. And both sides of three street sections were surveyed. Therefore, there should be further studies on heavily congested situations and many other street sections.

위 점액성 선암 수술 후 이시성으로 발생한 대장 점액성 선암

임태수,강동백,이정균,박원철 원광대학교 의과학연구소 2009 圓光醫科學 Vol.24 No.1

점액성 위암과 점액성 대장암은 각각 드물게 발생하는데 점액성 위암의 근치적 수술 후 10년이 지난 후에 복막 전이를 동반한 점액성 대장암이 발생한 증례가 있어 보고하는 바이다. Mucinous gastric and colon carcinoma is rare histopathologic type of each carcinoma. We report a case of metachronous mucinous carcinoma of colon in 74-year-old female, 10 years after curative gastric surgery. She came to hospital with pain on right upper quadrant. Abdominopelvic computed tomography showed mucinous carcinomatosis peritoni with descending colon cancer. We detected the descending colon cancer by colonoscopy and confirmed mucinous carcinoma by biopsy.

납 中毒된 흰쥐의 血液에 미치는 補中益氣湯의 影響(Ⅰ)

임종필,강창수,강태욱 又石大學校 1995 論文集 Vol.17 No.-

Lead acetate and Bojungiki-tang extract, a herbal restorative were treated p.o. 40㎎/㎏ and 500㎎/㎏ respectively and concurrently to mouse, and examined blood biochemical parameters and effects of metabolic enzymes of rats. The results obtained in this study are as follows: 1. The value of aspartate aminotrasferase(AST) of lead-treated group increased while the group of concurrent administration with BIT showed significant decrease and the value of alkaline phosphatase(ALP) of lead-treated group decreased while the group of concurrent administration with BIT showed significant increase. 2. The value of δ-aminolevulinic acid dehydratase(ALAD) of lead-treated group de creased while the group of concurrent administration with BIT showed significant in crease and the values of cytochrome p-450 in liver and kidney of lead-treated group increased while the group of concurrent administration with BIT showed significant decrease. The differences (%) of aniline hydroxylase and 2-thiobarbituric acid (TBA) of lead-treated group increased while the group of concurrent administration with BIT showed significant decrease. These results on the whole indicated that concurrent administration with BIT showed significant recovery from the toxicity of lead-treated group.

補中益氣湯이 납中毒된 흰쥐의 臟器重量에 미치는 影響

임종필,남궁동,강창수,강태욱 又石大學校 1994 論文集 Vol.16 No.-

Lead acetate and Bojungiki-tang extract, a herbal restorative were treated p. o. 40㎎/㎏ and 500㎎/㎏ respectively and concurrently to mouse, and examined variation of body weigh, accumulation of lead in organs of rats. The results obtained in this study are as follows: 1. Bojungiki-tang extract(BIT) resulted increase of body weight and the increase ratio of body weight in lead-treated group was dropped but the group of concurrent administration with BIT showed significant recovery. 2. The accumulation of lead in liver of lead-treated group increased but the group of concurrent administration with BIT showed significant decrease. 3. The ratio of liver weight/body weight of lead-treated group increased but the group of concurrent administration with BIT showed significant decrease. These results on the whole indicated that concurrent administration with BIT sowed significant recovery from the toxicity of lead-treated group.

관공서 이미지 향상을 위한 C.I.P에 관한 연구 : -진해시 C.I.P 이미지조사를 중심으로-

임태윤,강경봉 한국 비쥬얼 디자인학회 1998 한국디자인포럼 Vol.3 No.-

Arsenazo I-XAD-2 킬레이트수지를 이용한 U(VI) 이온의 분리 및 농축에 관한 연구

엄태윤,김인환,이창헌,강창희,이시은,이원,임재희 濟州大學校 基礎科學硏究所 1994 基礎科學硏究 Vol.7 No.1

Aresenazo I-XAD-2 킬레이수지를 합성하고 이 수지에 대한 U(VI)이온의 흡착 거동을 조사 검토하였다. 킬레이트수지는 Arsenazo I 킬레이트제와 Amberlite XAD-2의 디아조늄짝지움 반응에 의해서 합성하였으며 원소 분석법과 적외선 분광법으로 확인하였다. U(VI)이온흡착의 최적 조건을 찾기 위해서 pH, U(VI) 이온농도와 진탕 시간에 관해서 조사하였다. U(VI)이온에 대한 킬레이트수지의 전체 흡착능은 pH 4.0∼4.5 범위에서 0.39mmol U(VI)/g resin이었고, pH값이 증가함에 따라 흡착능이 증가하였다. Arsenazo I-XAD-2 킬레이트 수지에 대한 U(VI)이온의 흡착 메카니즘은 U(VI)이온과 H+ 이온 사이의 경쟁반응임을 확인하였다. 컬럼법으로 구한 U(VI) 이온의 돌파점 부피와 전체 흡착능은 각각 600ml, 0.38mmol U(VI)/g resin 이었다. 3M HNO₃와 3m Na₂CO₃의 탈착용액을 사용하여 구한 회수율은 90∼96%였다. 따라서 본 연구에서는 합성한 Arsenaso I-XAD-2 킬레이트수지는 자연수 바닷물 중에 함유된 U(VI)이온의 분리와 농축에 매우 유용함을 알았다. Some sorption behaviors of U(VI) ion on Arsenazo I-XAD-2 chelating resin were investigated. This chelating resin was synthesized by the diazonium coupling of Amberlite XAD-2 resin with Arsenazo I chelating reagent and characterized by elementary analysis method and IR spectrometry. The optimum conditions for the sorption of U(VI) ion were examined with respect to pH, U(VI) ion concentration and shaking time. Total sorption capacity of this chelating resin on U(VI) ion was 0.39 mmol U(VI)/g resin in the pH range of 4.0∼4.5. This chelating resin was showed increased sorption capacity on the increased pH value. It was confirmed that sorption mechanism of U(VI) ion on the Arsenazo I-XAD-2 chelating resin was competition reaction between U(VI) ion and H+ ion. Breakthrough volume and overall capacity of U(VI) ion measured by column were was 600ml and 0.38 mmol U(VI)/g resin, respectively. The desorption of U(VI) ion was showed recovery of 90∼96% using 3M HNO₃and 3M Na₂CO₃as a desorption solution. The separation and concentration of U(VI) ion from natural water and sea water was performed successfully by Arsenazo I-XAD-2 chelating resin.

화농성 슬관절염이 동반된 수막구균성 수막염 1예

김태연,유진홍,박성환,김연식,임상현,신완식,강문원,정창훈,최문구,강지민 대한화학요법학회 1997 대한화학요법학회지 Vol.15 No.2

저자들은 최근 화농성 슬관절염과 병발한 수막구균성 수막염 1예를 체험하였고, 이는 국내에서 아직 보고되지 않은 드문 예로 사료되어 문헌고찰과 함께 보고하는 바이다. We recently experienced a case of meningococcal meningitis associated with pyogenic arthritis in a 37-year old male patient. Pyogenic arthritis developed in right knee joint during treatment for meningococcal meningitis. He was treated successfully by appropriate antibiotics and arthroscopic irrigation. To our knowledge, such a rare case has not ever been reported in Korea, Hence we report this case with a review of related literatures.

水晶體 β-Crystallin의 Carboxylmethylation에 關한 硏究

李康一,郭相太,林圭 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.2

Changes of protein patterns of nonmethylated and endogenous or exogenous methylated β-crystallin fractions have been investigated, and then the methyl-acceptor proteins identified by urea /polyacrylamide gel electrophoresis. 1. Nonmethylated β_H and β_L-crystallin were separated in ten, eleven fractions, respectively. In the endogenous methylated β_H-crystallin, subfraction No. 10 was disappeared and No.3 was increased when compared with that of nonmethylated. In the β_L-cryallin, subfraction No.8, 10, 11 were decreased and No.6, 7 was increased. 2. When native β-crystallins were electrophoresed, subfraction No. 7, 9 disappeared and No.8b, 10b were newly appeared and. No. 6 was increased in methylated β_H-crystallin, and subfraction No. 11 was disappeared, No.9 was decreased and No.8 was increased in meth ylated β_L-crystallin. But, subfraction profile of methylted a-crystallin was not changed. 3. Methyl-acceptor proteins in each crystallin were subfraction No. 1, 6, 8 in a-crystallin, 2, 3, 6, l0a in β_H-crystallin and 1, 6, 7, 8, 10 in β_L-crystallin, respectively. These results suggest that the effect of carboxylmethylation on the aggregation of β-crystallin is related to not only the interaction of a, r-crystallin subfractions, but also the interaction of β-crystallin subfractions. On the other hand, a-crystallin is only related to the interaction of the other crystallin subfractions.

한국판 정신사회재활 성과 측정도구의 신뢰도 및 타당도 연구

황태연,강대엽,임영란,김명식,이원혜,박용범 용인정신의학연구소 1999 용인정신의학보 Vol.6 No.2