初·中·高 敎師의 人口敎育에 關한 知識 態度 및 敎育活動 調査

李淑姬 김천과학대학 1979 김천과학대학 논문집 Vol.7 No.-

A survey on knowledge, attitude, and behavior of primary, middle and high school teachers with regard to population education was conducted by the author through three provinces for 20 days from September 10, 1979. A total 606 teachers was interviewed with use of a questionaire. Results of the survey are as follows; 1. More than half of respodents (63.0%) had got instruction related to population and its problems. They had been exposed to population related instruction from their schooling, special meetings or seminars. 2. Only 33% of all teachers knew correctly the recent number of Korea population. Most of teachers felt that Korean population is growing rapidly. 3. As for deciding which problems deserve the most serious consideration among those problems caused by over-population, many of respondents chose "Social problem"(37.1%). "Food problem"(36.1%), "problem of economic growth"(13.4%) were chosen secondly and thirdly, respectively. 4. Sixty-eight percent of teachers who strongly agreed to introduce more population and family planning material into school curriculum, would talk about population matters during their classwork with pleasure.(p<0.01). 5. As for appropriate courses for introducing population and family planning matters, they though that those should be handled within social studies (32.2%) and every courses(30.2%). Only 19.8% of teachers who thought that those should be handled in an independent course, reported that this course should be taught by the school health theacher. 6. As for appropriate level of instruction on population, sexual morality and family planning, many teachers (46.5%) reported that education in sexual morality should be introduced from fourth grade of primary school. Over one-third(38.4%) of respondents had the opinion that matters related to population should be introduced at the middle school level. 42.6% of teachers favored introducing family planning material at the high school level. 7. Seventy-three percent among teachers who had taught the courses handled matters related to population, had had instruction about population through special meetings or seminars. (p 0.01). 8.A great majority (82.0%) of teachers felt that they would be useful to learn more about population matters in their own schooling or through special seminars. 9. Teachers during their class-work had talked about the population matters (69.3%), sexual morality (29.3%) and family planning (8.1%). 10. Twenty-five percent of the primary school teachers, 37.2% of middle school teachers and 48.7% of high school teachers had given counsel to their students. (p 0.01). The major import of a counsel was the intersexual matters (39.6%), and 47.2% of those who had given counsel, were very anxious about the social intercourse between boys and girls. 11. Over half(57.5%) of respondents had been practicing contraception, most of respondents (75.4%) wanted to recieve favors on family planning from the health-centers and other hospitals. Certainly an effort should be made any family planning educational program to link population size and to family size. 12. A strong preference for sons among male teachers (61.9%) showed higher rate than those among female teachers (34.9%).

GC 및 GC/MS에 의한 생체시료중 Methidation의 분석법에 관한 연구

이종숙,이재신,최동기,양희진,한백희,구기서 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

경상도 별미김치의 표준화 연구

한지숙,이숙희,이경임,박건영 동아시아식생활학회 1995 동아시아식생활학회지 Vol.5 No.2

This study was conducted to standardize ingredient ratio and preparation method of major traditional special kimchies in Kyungsang province, Korea. There were about 35 varieties of special kimchi in Kyungsang province. Six varieties of them such as burdock kimchi, wild leek kimchi, green thread onion kimchi, perilla leaf kimchi, Godulbaegi(Korean wild lettuce) kimchi, and red pepper leaf kimchi were selected, because they tasted good and the physiological functions of their main ingredients were excellent. The ingredient ratios of the selected special kimchi were standardized through surveying hereditary preparation of some families in Kyungsang province and using the literatures including cooking books. The standardized ingredient ratio of the burdock kimchi was 15.1 pickled anchovy juice, 6.8 red pepper powder, 5.7 garlic, 2.2 ginger, 18.0 rice flour paste, 13.5 green thread onion, and 1.2 sesame seed in proportion to 100 of burdock. The standardized preparation step of the selected special kimchies was similar except some preprocessing methods of main ingredients. The diagonally cut-up burdock was usually parboiled or soaked in salted water, then it was mixed with the other ingredients. Wild leek and green thread onion were usually pickled with salt or pickled anchovy juice. Sometimes the green thread onion pickled was dried in the sun. General preprocessing of perilla leaf, Korean wild lettuce, and red pepper leaf was soaking them in salted water for about 5-10 days. Sometimes red pepper leaf was heated with steam and dried in the sun, then it was mixed with the other ingredients.

리놀레산 함유 고형 모델시스템의 산화에 미치는 토코페롤 및 베타 카로틴의 영향

김명,이숙희,최홍식 부산대학교 유전공학연구소 1995 분자생물학 연구보 Vol.11 No.-

리놀레산 혼합물 (리놀레산 64.6%, 올레산 27.4%, 기타 8.0%)에 토코페롤 isomer 및 β-카로틴을 조합한 모델시스템에서는 정제 잣 지방질에 비해 비교적 낮은 온도인 35℃에서도 급속한 산화가 일어났으며 α-토코페롤은 항산화제로 작용하나 첨가농도가 0.05% 보다 높을수록 오히려 산화촉진 효과를 나타내어 본 실험에서도 0.05% 첨가가 산화 안정성을 유지하는 적정농도라고 추정되었다. γ-토코페롤은 항산화작용을 나타내었고 이 때는 α-토코페롤과는 달리 농도에 다른 항산화력의 차이는 나타나지 않았다. 또한 동일 농도에서 α-토코페롤에 비해 γ-토코페롤의 항산화효과가 크며, 동량 혼합시에는 다소 유도기가 연장되었으며 토코페롤의 감소 경향은 α-, γ-순이었다. β-카로틴은 자동산화 초기에 항산화제로 작용하였으나 γ-토코페롤이 함께 존재할 경우에는 산화를 촉진하는 것으로 나타났으며 β-카로틴의 분해는 지방질의 산화가 진행됨에 따라 급격히 일어났다. 따라서 지방질(유리지방산 상태)의 산화안정성에는 β-카로틴 보다 토코페롤의 영향이 크다고 볼 수 있었다. Effects of tocopherols and β-carotene on the oxidation of the solid model system of a free fatty acid mixture (64.5% of linoleic acid ; 26.4% of oleic acid ; 5.0% of palmitic acid) with tocopherols and β-carotene were studied. α-tocopherol revealed an antioxidant activity at the concentration below 0.05%, however, it showed a prooxidant activity when the concentration was higher than 0.05%. The antioxidant activity of γ-tocopherol was not affected by the concentrations in the range of 0.01∼0.10% in the model and γ-tocopherol showed higher antioxidant activity than that of α-tocopherol. It seemed that α-tocopherol was unstable compared to γ-tocopherol during oxidation. β-carotene showed a weak antioxidative activity at the initial stage of this system while β-carotene showed a prooxidant activity in the presence of tocopherol. β-carotene was highly susceptible to autoxidative degradation during oxidation.

된장의 항돌연변이 효과 : 된장찌개 및 된장국의 Aflatoxin B₁에 대한 돌연변이유발 억제효과 Inhibitory Effect of Doenjang Stew and Soup on the Mutagenicity Induced by Aflatoxin B₁

박건영,문숙희,이숙희 A.R. Liss 1994 ENVIRONMENTAL MUTAGENS AND CARCINOGENS Vol.14 No.2

죽염 처리 청국장의 기능성 증진

김수옥,박수영,이숙희,박건영 대한암예방학회 2003 Journal of cancer prevention Vol.8 No.4

버섯첨가된장의 생리활성 작용

이수진,이경임,이숙희,박건영 한국조리과학회 2004 한국식품조리과학회지 Vol.20 No.4

The study was carried out to evaluate the radical scavenging activity, and antimutagenic and anticancer effects in Korean soybean paste(doenjang) added with various mushrooms. Ganoderma lucidum doenjang(Gl-TD) showed significant inhibitory activity against the 1,1-diphenyl-2-picrylhydrazyl(DPPH) radical, with an IC50 value of 245㎍/㎖. In contrast, the other doenjang varieties appeared to have weaker antioxidant activity. Four kinds of doenjang didn't have any antimutagenic activity against N-methyl-N'-nitro-N-nitrosoguanidine(MNNG) by adding of 5mg/plate, but exhibited a strong inhibitory effect(55~70%) against aflatoxin B1(AFBI). Especially Phellinus linteus doenjang(Pl-TD) inhibited more than 70% of the mutagenicity induced by AFBI in Salmonella typhimurium TA100. On the other hand, the mushroom doenjang varieties showed relatively weak activity toward MNNG in SOS chromotest, their inhibitory rate ranging from 23% to 33%. Methanol extracts of Gl-TD and Pl-TD inhibited by 91%~92% the growth of AGS gastric cancer cells in a concentration of 100㎍/㎖.

김치 추출물에 의한 Aflatoxin B_1의 돌연변이 억제 효과

황승영,허영미,최영현,이숙희,박건영,이원호 부산대학교 유전공학연구소 1997 분자생물학 연구보 Vol.13 No.-

The inhibitory effects of Kimchi extracts on the mutagenicity induced by aflatoxin B₁(AFB₁) in Salmonella and Drosophila assay systems were studied. The kimchi extracts had inhibitory activity for His^+ to His^+ reverse-mutations induced by AFB₁acting on S. typhimurium TA98. A similar inhibitory effect was detected in somatic cell mutation assaying system of D. melanogaster. In Drosophila wing hair spot test, mutant clone frequency induced by AFB₁was consideranly inhibited by the kimchi extracts. These facts suggest that kimchi rxtracts can inhibit gene mutation, deletion, mititic chromosomal recombination and suppress the formation of cancer and mutation by DNA damage.

Phytol과 들미나리추출물이 Sarcoma 180마우스의 T Subset에 미치는 효과

류태형,박건영,장명웅,이숙희,선우양일,김광혁 東亞大學校附設基礎科學硏究所 1993 基礎科學硏究論文集 Vol.10 No.1

본 연구는 녹황색채소류에서 추출되어 항암효과를 나타내는 활성물질로 보고 되어 있는 phytol과 들미나리추출물을 sarcoma 180마우스에 주사한 후 적출한 비장세포내 T 임프구와 T subset, 그리고 asialo ?? 세포를 정량하여 다음과 같은 결과를 얻었다. 1) 종양 마우스에 phytol을 투여하였을 때 비장세포내의 T cell과 T-subset은 종양세포이식에 의하여 상승된 치를 더욱 증가시켰다. 그러나 들미나리추출물의 경우는 대동소이하였다. 2) Asialo ?? 세포는 종양마우스에 phytol이나 들미나리추출물을 주사하였을 때 모두 상승하였으며 정상마우스에 phytol을 투여하였을 때도 대조군에 비하여 상승했지만 들미나리추출물을 작용시켰을 때는 저하되었다. 3) ??/?? 세포비는 종양마우스에 phytol을 주사하였을 때 감소를 보였지만 정상 마우스에 투여하였을 때는 더욱 크게 낮아졌다. 그러나 들미나리추출물을 정상마우스에 투여하였을때는 크게 감소하던 것이 종양마우스에 적요 시켰을때는 증가현상을 보였다. 이상의 결과로 미루어 볼 때 phytol이나 들미나리추출물은 종양마우스에서 작용자세포인 자연살해세포(natural killer cell)의 활성인자로서 작용할 가능성이 높을 것으로 사료된다. Several studies have shown that phytol isolated from perilla leaf and small water dropwort(Oenanthe javanica(BL)D.C, wild type)extract reveal antitumor activities. In the present study we investigated the effect of phytol and the small water dropwort extract on the T subset in the sarcoma 180-transplanted mice in order to elucidate the immunological mechanism of antitumor activity of these substances. The results obtained from the experiment were as follows : When phytol was injected into the sarcoma-180 transplanted mice(control), the levels of T cell and T subset by inoculation of the tumor cells were enhanced, but that of T cells in case of small water dropwort extract was similar to the control. Asialo ?? cells were increased when phytol or small water dropwort extract was injected into tumor-transplanted mice. In normal mice the number of asialo ?? cells increased with phytol injection and decreased with small water dropwort extract injection. ??/?? cell ratios were decreased when phytol was injected into tumor-transplanted mice, but increased in case of small water dropwort extract injection. In normal mice the ratios showed large decreases with phytol or small water dropwort extract injection. These results indicate that phytol or small water dropwort extract can activate the proliferation of natural killer cells that are effector cells in tumor-bearing mice.

들깻잎에서 동정한 Phytol의 항암 및 면역활성증강 효과

선우양일,류태형,박건영,이숙희,장명웅,김광혁 東亞大學校附設基礎科學硏究所 1993 基礎科學硏究論文集 Vol.10 No.1

Several studies have shown that extracts from yellow-green vegetables reveal antitumor activities. In the present study we investigated the effect of phytol in order to elucidate the immunological mechanism of antitumor activity of this substance. The results obtained from the experiment as follows : 1) Phytol showed cytotoxic effect on sarcoma 180 cells in vitro. 2) When phytol was injected into the peritoneal cavity of mice transplanted with sarcoma 180 cells, the average survival time(24.0 days) tended to increase as compared with the nontreated control(19.2 days). 3) When sarcoma 180 cells were injected subcutaneously into the right groin of mice and then phytol was injected into the peritoneal cavity the tumor inhibition ratio was 33%. 4) The natural killer(NK) cell activity was significantly augmented by phytol in vitro and in vivo. Similar augmentations of NK cell activity were obtained with culture supernatants of phytol exposed spleen cells and peripheral blood mononuclear cells. 5) Phytol on the macrophage from peritoneal cavity showed a higher effectiveness in vivo than in vitro. These results indicate that phytol shows the inhibitory effect for growth of sarcoma 180 cells in vitro, also it can augment macrophage and NK cell activities in vivo.