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      • 詩經正變設考

        金時俊 서울대학교 동아문화연구소 1979 東亞文化 Vol.16 No.-

        It was written at the Mao Shi prefaces (毛詩序) that Shi Jing was divided into two groups; the Zheng Poem and the Bian Poem. According to this, many scholars published various assertions on how to distinguish the Zheng Poem from the Bian Poem in Shi Jing. Conseguently, these assertions were classified into four sorts. 1) Classification by the chronological order according to the political rise and fall 2) Distinction between eulogy and satire 3) Distinction the Poem which was accompanied by music from the poem which was not accompanied by it, 4) Classification by the style of the poem My study on each assertion leads to the following conclusion: 1) Although those scholars who made the first assertion defined that Shi Jing was published by the chronological order and they distinguished the Zheng Poem from the Bian poem by the table of contents, it is proved that Shi Jing was not published by the chronological order. 2) Those scholars who made the second assertion concluded that Shi-Jing was distinguished between eulogy and satiry at every prologue in Mao Shi and that the Zheng poem and the Bian Poem could be divided into eulogy or satire accordingly. But it is proved herein that the distinction eulogy from satire in Mao Shi prefaces was possible by the country and chronology without the definite standard even though the contents of the poem were the same. 3) Those scholars who made the third assertion divided Shi Jing into two parts. One that was accompanied by music was called the Zheng Poem and the other that was accompanied by music was called the Bian Poem. But it is proved that all of Shi Jing were accompanied by music 4) Those who made the fourth assertion distinguished between the Zheng Poem and the Bian Poem by the style of the Poem. But looking into the style, it is proved that the distinction between the Zheng Poem and the Bian Poem is the style itself. Thus, the above classifications seem to be unreasonable so far. Then, why did these assertions come to rise? These assertions were due to the Han scholars who regarded the poem as a remonstration. They attempted to classify the Zheng Poem as the poem of admonition and the Bian poem as that of warning. But they did not succeed in it.

      • Blocking of Cell Proliferation, Cytokines Production and Genes Expression Following Administration of Cordyceps Sinensis in the Bronchoalveolar Lavage Fluids Cells

        Kuo, Yuh-Chi,Wu, Chia-Lin,Tasi, Wei-Jern,Wang, Jir-Yenn,Chang, Shi-Chung,Lin, Ching-Yuang,Shiao, Ming-Shi 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

        Yuh-Chi Kuo¹,Chia-Lin Wn¹,Wei-jern Tasi¹,Jir-Yenn Wang²,Shi-Chung Chang₃,Ching-Yung Lin⁴,and Ming-Shi Shiao⁴¹National Research Institute of Chinese Medicine, ²Department of Biology,Fu Jen University, ³Department of Chest, ⁴Department of Pediatrics, □De[art,amt of Medical Research and Education. Taipei Veterans General Hospital, Taipei, Taiwan Yuh-Chi Kuo¹,Chia-Lin Wn¹,Wei-jern Tasi¹,Jir-Yenn Wang²,Shi-Chung Chang²,Ching-Yung Lin³,and Ming-Shi Shiao⁴.¹National Research Institute of Chinese Medicine, ²Department of Biology,Fu Jen University, ³Department of Chest, ⁴Department of Pediatrics, □De[art,amt of Medical Research and Education. Taipei Veterans General Hospital, Taipei, Taiwan. Blocking of Cell Proliferation, Cytokines Production and Genes Expression Following Administration of Cordyceps sinensis in the Bronchoalveolar Lavage Fluids Cells. Proceedings of international Symposium on East-West Medicine, Seoul. 44-64, 1999.-Cordyceps sinensis is a major parasitic fungus on larva of Lepidoptera. It is one of the well know fungi used in traditional Chinese medicine for treatment asthma, lung and kideney diseases. Many fungi belonging to the genus Cordyceps have been demonstrated to produce natural products with various biological activities. Reported biological activities of genus cordyceps include:(a)inhibition of DNA and RNA synthesis;(b)enhancement of cell differentiation;(c)restruction of cytoskeleton;(d)inhibition of protein kinase activity;(e)antitumor activity on bladder, colon, lung carcinoma as well as fibroblastoma;(f)inhibition of the infection and revers transciptase activity of human immunodeficiency virus type 1; and(g) inhibition of methylation of nucleic acid. Thus, it is suggested that the extracts of Cordyceps sp. Contain antitumor, antiviral, and many other biological activities. In our previous studies, we proved that C. sinensis contains the antitumor and immunomodulatory agents. In the present studies, effects of C. sinensis on bronchoalveolar lavage fluids(BAL)cells were demonstrated. The crude methanolic extracts of C. sinensis were fractionated into 15 fractions by silica gel column chromatography. Effects of various fraction on BAL cells proliferation and lipopolysaccharide(LPS) stimulated interleukin-1β(IL-8),platelet activating factor(PAF), interleukin-6(IL-6), tumor necrosis factor-α(TNF-α),and interleukin-8(IL-8) production on BAL cells were determined. The result indicated that the CS-19-22 fraction suppressed BAL cells proliferation activated by LPS. The median inhibitory concentration(IC50) was 6㎍/ml. The CS-19-22 fraction also decreased IL-1β,PAF,IL-6, TNF-αand IL-8 production.The results of revers transcription-polymerase chain reaction(RT-PCR) demonstrated that the CS-19-22 fraction did not affect IL-1β,PAF,IL-6, TNF-α,and IL-8 mRNAs expression in BAL cells activated by LPS. By contrast, it inhibited the IL-10 mRNA expression but enhanced IFN-γand IL-12 mRNAs expression in activated BAL cells. Moreover, the CS-19-22 fraction blocked PAF-induced platelet aggregation. It is unlikely that cytotoxicity was involved. Because no cell deths were observable. We hypothesize that inhibitory mechanisms of CS-19-22 on BAL cells proliferation may be related to the impairments of gene expression and production of cytokines in BAL cells. The explanation of C. sinensis antiasthma function may involved the following(1)C.sinenesis contained immunomodulatory agents that stimulated IFN-γand IL-12 expression in TH1cells.(2)Enhanced secretion of IFN-γand IL-12 will inhibit the Tγcells immune responses Ex. Decreasing of IL-6 and IL-10 production.(3) The impairments of cytokines production in TH2 cells suppressed th BAL cells proliferation then more cytokines production Ex.IL-1β,PAF,IL-6,TNF-αand IL-8 in activated BAL cells were decreased. (4)The suppression of TH2cells immune responses will inhibit the growth and differentiation of B cells then IgE production will be decreased. (5)Reduced production of IgE will decreased asthma attack occurring in individuals. However, the results of the present study suggested that C. sinensis may also have acted to treat asthma in part by inhibiting BAL cells proliferation and cytokine gene expression and production. Future, experiments with treatment of animals with asthma with C. sinensis will be necessary to defined whether C. sinensis can reduce asthma injury. Plans are underway for the isolation of pure principal growth inhibitors and their mechanisms of action are subjected for further study.

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        Hot Deformation Characteristics and Processing Map Analysis of Pre-Forged AZ80 Magnesium Alloy

        Shi‑quan Huang,Ming Lu,Sheng‑lan Luo,Hai‑lin He,You‑ping Yi 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.5

        The hot deformation behavior of pre-forged AZ80 magnesium alloy is investigated by the isothermal compression tests attemperatures of 523–683 K and strain rates of 0.0001–0.1 s−1, and analyzed by the processing maps for guiding isothermaldie forging. Flow localization and even cracking occurs at low temperatures and high strain rates, where shear deformationdegree shows a positive correlation with the ��( ̇�� ) value. Two stability regions with high efficiency is found out by theprocessing maps. At common stability region with high temperatures and low strain rates, peak power dissipation efficiencydoes not represent optimum deformation condition as reported in other materials. A Z parameter criterion is introduced forparameters optimization. javascript:void(0); a new stability domain of 523–590 K and 0.0001–0.01 s−1 is observed, which istypical for fine microstructure composed of equiaxed clean α-Mg grains and big particles both about 1 μm (573 K/0.01 s−1).Super plasticity is speculated to occur at that condition.

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        정신분열증 환자의 性(Sexuality)에 관한 임상적 고찰

        최시현 大韓神經精神醫學會 1982 신경정신의학 Vol.21 No.3

        1981년 8월부터 1982년 2월말까지 국립정신병원에 입원중인 정신분열증 환자 358명 중 조사 가능한 260명(남 124명, 여 136명)을 대상으로 하여 이들의 개인적 배경 전반을 알아보고, 性的행동장애, 思考 및 知覺상에 보인 性的문제에 대한 발현양상 및 빈도를 中心으로 조사한 결과 다음의 몇가지 특징을 알 수 있었다. 1) 性的문제를 보인 환자의 男女比는 비슷했고 20-30대가 93%로 거의 대부분이었고, 학력은 고졸 이상이 84%로 비교적 높은 교육정도를 보였고, 대부분이 미혼이었으며 아형별 진단분포는 만성미분화형과 망상형이 대다수였다. 2) 정신분열증환자, 특히 망상형과 만성미분화형의 환자들이 그들의 사고와 지각 및 행동에 있어 性的문제를 상당수에서(38.8%) 가지고 있었다. 사고면에서는 123례(47.3%)였고, 지각에서는 50례(19.2%)였으며, 행동에서는 108례(41.5%)의 빈도를 보였다. 3) 사고장애에서, 과도한 이성에의 집착이나 근친상간 및 사고나 충동의 대다수(90.9%)가 발병전에 이미 경험된 예였고, 동성애적 경향을 보인 환자의 63.6%가 망상형이었다. 지각장애에서 女子는 환청이, 男子는 환시가 性比상 다소 많았고, 환후는 적었다(1.9%), 행동면에서 독신주의, 성적무감동, 성욕 全無 등이 13.8%로 가장 많이 나타난 것은 장기간 입원의 결과와 향정신약물의 영향을 배제키 어려웠다. 근친상간이나 강간의 경우 대부분 조정망상, 환각과 현실감 결여로 인한 점이 주목할만 하였다. 4) 성적 망상이나 환각이 단독으로 존재하는 경우는 드물며 대부분 다른, 과대, 피해, 정치 등의 망상 내용과 복합된 양상으로 존재하고 있었다. 5) 정신분열증 환자에서 性(Sexuality)에 관련된 부분이 상당한 부분(38.8%)을 차지함으로 향후 이 부문에 원인적, 역동학적, 현상학적인 각 측면에 대한 보다 광범위하고 체계적인 연구가 이루어져야 할 것으로 생각된다. The author attempted to study the sexuality in schizophrenic patients in terms of their sexual bebaviors, thought and perceptal disturbances by the method of statistical evaluation. The subjects are 260 schizophrenic patients who were hospitalized in National Mental Hospital during the period of seven months(Aug. 1, 1981-Feb. 28, 1982). Some of their characteristics are as follows: 1) Sex ratio is about the same(F:F; 1:1.1). The marital state is more than half of them(69.3%) are single. The divorce or seperated one are 4.0%. In the educational level, more than three-fourth of them(84.1%) are high school graduates. Regarding to subtype chronic undifferentiated and paranoid types consist of 91.1% of total cases. 2) The majority of patients show sexual problems in their behaviors(41.5%), disturbance in thoughts(47.3%) and perceptions(19.5%). 3) In their thought disturbances, the preoccupation of hetero sexual matters(90.9%), the incestuous thoughts and ipulses(81.0%) occurred mostly at prepsychotic period. The homosexual tendency is predominant(63.6%) in paranoid type. In perceptual disturbuuces, the female shows more of auditory and the male shows of more of visual hallurination. however, the olfactory hallucination(1.9%) is less common both sexes. In the sexual behaviors, the celibacy, the seual apathy, and libidinal impotence are commonly seen in this study(13.8%). The reason seems to be related to the chronicity of hospitalization could we exclude side-effects from neuroleptics. The subject, who committed incest and or rape reveal the symptoms of idea of references, hallucinations and poor reality Resting. 4) The sexual nature of delusion or hallucination is rarely occurred singly, instead they occur mostly in combined, such as various combinations of grandiose, persecutory, religious, predictive and political themes. As a concluding remark, the author strongly feels that the sexual problems in schizophrenic patients appear to be common phenomenon. Thus the more organized studies in terms of etiology, psychodynamics, and phenomenology of sexuality in the schizophrenics are needed.

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        과잉치로 인한 정중이개의 술후 자발적 폐쇄의 치험례

        김시형,김영진,남순현 大韓小兒齒科學會 1995 大韓小兒齒科學會誌 Vol.22 No.2

        The diastema is defined as a space greater than 0.5millmeter between the proximal surfaces of adjacent teeth. It is a normal stage in the primary dentition and the early mixed dentition(i.e. Ugly duckling stage), especially between the ages of 7 and 12 years. Usually these diastmas close completely after eruption of permanent maxillary cuspid. Genetic factor, heavy labial frenum, habits, degree of deep bite, direction of long axis of incisor and mesiodens can cause midilne diastema. Of these, mesiodens located between both maxillary central incisors can cause diastema. The present case reports show that the abnormal midline diastema caused by mesiodens during Ugly-ducking stage have become spontaneous closure after surgical removal.

      • 우리나라의 耕地汎用化 事業動向과 그 問題點의 解決方案 模索

        金始源,呂運植,金瀅中,金善柱 建國大學校 附設 農業資源開發硏究所 1993 農資源開發論集 Vol.18 No.-

        To make a smooth progress in the multi-utilization undertaking of paddy land, land consolidation is the most important task among the various countermeasures. This study discusses the types and efficiency of subsurface drainage systems, and suggestes their maintenance and management schemes. The results are summarized as follows: 1) Recently an introduction of subsurface drainage systems has been employed. Especially the necessity of subsurface drainage systems has been widely recognized at farms in the suburban districts, however, the undertaking itself cannot overcome an experimental stage. Therefore, studies on the selection of project areas and operation systems should be executed together with the technical establishment. 2) To drive forward the land improvement project reasonably and efficiently, the realities of regional farmings and the natural conditions should be considered, so it is desirable to establish a longterm land improvement plan based on the nation-wide angle of view. 3) To create the multi-utilization paddy land from the single cropping paddy land, the following items should be consolidated. First, reorganize the utilization pattern of paddy land possible to adopt multi-utilization system. Second, land should be consolidated as a large size possible to operate big agricultural machines. Third, develop fundamental techniques for the multi-utilization system. Fourth, collectivization of agricultural land. Fifth, environmental consolidation of the rural community. 4) The maintenance and management technique of the subsurface drainage system should be studied. Since the function of system could be lost by the clog up of drainage pipe, the efficiency and function of system should be recognized for the smooth maintenance and management.

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