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( Piao¸ S. Y. ),( Z. R. Li ),( Y. C. Sun ),( J. I. Lee ),( Y. E. Amanor ) 강원대학교 농업생명과학연구원(구 농업과학연구소) 2020 강원 농업생명환경연구 Vol.32 No.S
Rice is an important staple cereal for many households in Ghana. This study examines the factors that influence consumers’ preference for rice. Using questionnaires, 300 rice consumers, who were sampled across the municipality, were interviewed. Descriptive statistics, factor analysis, and multinomial logistic regression model were used to analyze the obtained data. The rice-related attributes that showed marked influence on consumers’ preference for rice were packaging quality, swelling capacity, stickiness of grains after cooking, percentage of broken grains, market availability, price, and degree of whiteness. Therefore, the stakeholders should implement strategies to improve these rice-related attributes and enhance the rice post-harvest chain.
Long Piao(Long Piao),Kwangho Jung(Kwangho Jung) 한국학술연구원 2022 Korea Observer Vol.53 No.4
This paper explores the diverse ways Chinese policymakers view the foreign policy process in China. Two approaches characterize conventional accounts of the foreign policy decision-making process. One of these, based on Graham Allison's rational, organizational, and bureaucratic politics models, focuses on intragovernmental aspects of foreign policy decision-making processes, while the other highlights extra-governmental domestic and foreign factors. However, these approaches have neglected the question of who leads foreign policy and how state, society, and grassroots interact through coalition. We interviewed Chinese scholars and foreign policy experts using Q statements to explore China's foreign policy response to South Korea's deployment of THAAD. Our findings offer new theoretical insights into China's foreign policy process by identifying statedriven, grassroots-based, and state-society coalition models.
Rapid Identification and Characterization of Antioxidants from Ligularia fischeri
Xiang-Lan Piao,Xiao-Yuan Mi,Yan-Ze Tian,Qian Wu,Hui-Shan Piao,Zhikai Zeng,Xiangshu Piao,Ding Wang 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.12
The objectives of this study were to investigate the radical-scavenging activity of Ligularia fischeri on oxidative damage by the radical 1,1-diphenyl-2-picrylhydrazyl (DPPH) and to rapidly identify the active components using the bioassay-linked fractionation method. The MeOH extract and fractions of CH2Cl2, BuOH, and H2O from L. fischeri showed DPPH radical-scavenging effects in a dose-dependent manner (p < 0.01). In particular, the BuOH fraction had the most effective (p < 0.05) antioxidative capacity. The active constituents from the BuOH fraction of L. fischeri were rapidly isolated by bioassay-linked HPLC method and identified as hyperoside and 2''-acetylhyperoside with potent antioxidant effects against the DPPH radical, with IC50 values of 1.31 and 7.09 μg/mL, respectively. They have not been reported from L. fischeri yet.
박연희(Yanji Piao),김민지(Minji Kim) 한국IT서비스학회 2020 한국IT서비스학회지 Vol.19 No.1
With the development and widespread application of online shopping, the number of online consumers has increased. With one click of a mouse, people can buy anything they want without going out and have it sent right to the doors. As consumers benefit from online shopping, people are becoming more concerned about protecting their privacy. In the group buying scenario described in our paper, online shopping was regarded as intra-group communication. To protect the sensitive information of consumers, the polynomial-based encryption key sharing method (Piao et al., 2013; Piao and Kim, 2018) can be applied to online shopping communication. In this paper, we analyze security problems by using a polynomial-based scheme in the following ways : First, in Kamal’s attack, they said it does not provide perfect forward and backward secrecy when the members leave or join the group because the secret key can be broken in polynomial time. Second, for simultaneous equations, the leaving node will compute the new secret key if it can be confirmed that the updated new polynomial is recomputed. Third, using Newton s method, attackers can successively find better approximations to the roots of a function. Fourth, the Berlekamp Algorithm can factor polynomials over finite fields and solve the root of the polynomial. Fifth, for a brute-force attack, if the key size is small, brute force can be used to find the root of the polynomial, we need to make a key with appropriately large size to prevent brute force attacks. According to these analyses, we finally recommend the use of a relatively reasonable hash-based mechanism that solves all of the possible security problems and is the most suitable mechanism for our application. The study of adequate and suitable protective methods of consumer security will have academic significance and provide the practical implications.
Piao, Yongjun,Piao, Minghao,Park, Kiejung,Ryu, Keun Ho Oxford University Press 2012 Bioinformatics Vol.28 No.24
<P>Gene selection for cancer classification is one of the most important topics in the biomedical field. However, microarray data pose a severe challenge for computational techniques. We need dimension reduction techniques that identify a small set of genes to achieve better learning performance. From the perspective of machine learning, the selection of genes can be considered to be a feature selection problem that aims to find a small subset of features that has the most discriminative information for the target.</P>
Prognostic Value of T Cell Immunoglobulin Mucin-3 in Prostate Cancer
Piao, Yong-Rui,Piao, Long-Zhen,Zhu, Lian-Hua,Jin, Zhe-Hu,Dong, Xiu-Zhe Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6
Background: Optimal treatment for prostate cancer remains a challenge worldwide. Recently, T cell immunoglobulin mucin-3 (TIM-3) has been implicated in tumor biology but its contribution prostate cancer remains unclear. The aim of this study was to investigate the role of TIM-3 as a prognostic marker in patients with prostate cancer. Methods: TIM-3 protein expression was determined by immunohistochemistry and Western blotting in 137 prostate cancer tumor samples and paired adjacent benign tissue. We also performed cell proliferation assays using 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyl- 2H tetrazolium bromide (MTT) and cell invasion assays. The effects of small interfering RNA (siRNA)-mediated knockdown of TIM-3 (TIM-3 siRNA) in two human prostate cancer cell lines were also evaluated. Results: TIM-3 expression was higher in prostate cancer tissue than in the adjacent benign tissue (P<0.001). High TIM-3 expression was an independent predictor of both recurrence-free survival and progression-free survival. TIM-3 protein was expressed in both prostate cancer cell lines and knockdown suppressed their proliferation and invasion capacity. Conclusions: TIM-3 expression is associated with a poor prognosis in prostate cancer. Taken together, our resutlts indicate that TIM-3 is a potential prognostic marker in prostate cancer.
Mechanosensitivity of voltage-gated K<sup>+</sup> currents in rat trigeminal ganglion neurons
Piao, Lin,Ying Li, Hai,Park, Chul-Kyu,Cho, Ik-Hyun,Piao, Zheng Gen,Jung, Sung Jun,Choi, Se-Young,Lee, Sung Joong,Park, Kyungpyo,Kim, Joong-Soo,Oh, Seog Bae Wiley Subscription Services, Inc., A Wiley Company 2006 JOURNAL OF NEUROSCIENCE RESEARCH - Vol.83 No.7
<P>We investigated the mechanosensitivity of voltage-gated K<SUP>+</SUP> channel (VGPC) currents by using whole-cell patch clamp recording in rat trigeminal ganglion (TG) neurons. On the basis of biophysical and pharmacological properties, two types of VGPC currents were isolated. One was transient (I<SUB>K,A</SUB>), the other sustained (I<SUB>K,V</SUB>). Hypotonic stimulation (200 mOsm) markedly increased both I<SUB>K,A</SUB> and I<SUB>K,V</SUB> without affecting their activation and inactivation kinetics. Gadolinium, a well-known blocker of mechanosensitive channels, failed to block the enhancement of I<SUB>K,A</SUB> and I<SUB>K,V</SUB> induced by hypotonic stimulation. During hypotonic stimulation, cytochalasin D, an actin-based cytoskeletal disruptor, further increased I<SUB>K,A</SUB> and I<SUB>K,V</SUB>, whereas phalloidin, an actin-based cytoskeletal stabilizer, reduced I<SUB>K,A</SUB> and I<SUB>K,V</SUB>. Confocal imaging with Texas red-phalloidin showed that actin-based cytoskeleton was disrupted by hypotonic stimulation, which was similar to the effect of cytochalasin D. Our results suggest that both I<SUB>K,A</SUB> and I<SUB>K,V</SUB> are mechanosensitive and that actin-based cytoskeleton is likely to regulate the mechanosensitivity of VGPC currents in TG neurons. © 2006 Wiley-Liss, Inc.</P>
Pharmacokinetic study of mucoadhesive metformin pellets in rats
Jingshu Piao,Ji-Eun Lee,신대환,김진석 한국약제학회 2012 Journal of Pharmaceutical Investigation Vol.42 No.3
Previously, we have reported the preparation and characterization of mucoadhesive pellets of metformin hydrochloride using four high-viscosity polymers including hydroxymethylcellulose (HPMC), HPMC/carbopol, sodium carboxylmethylcellulose (Na-CMC) and sodium alginate (Na-Alg) (Piao et al., Arch Pharm Res 32:391–397, 2009). Here, pharmacokinetic and pharmacodynamic evaluation of these metformin pellets was performed. Metformin pellets were administered orally to normal and streptozotocininduced diabetic rats at 100 mg/kg dose and the blood concentration of metformin and blood glucose levels were determined. The area under the plasma concentration versus time curve from the Na-Alg-coated metformin pellets in normal rats was 69.93 ± 39.63 lg h/mL and it was the highest among tested, followed by Na-CMC-coated pellets (58.38 ± 5.19), HPMC/carbopol-coated pellets (52.24 ±5.29), HPMC-coated pellets (42.70 ± 14.29) and metformin aqueous solution (33.49 ± 2.04). The Cmax from the Na-Alg-coated metformin pellets in normal rats was 29.47 ±10.74 lg/mLand itwas the highest among tested, followed by Na-CMC-coated pellets (15.10 ± 2.73), HPMC/carbopolcoated pellets (11.38 ± 3.04), HPMC-coated pellets (11.29 ± 3.85) and metformin aqueous solution (6.92 ±0.83). The area under the effect versus time curve of the Na-Alg-coated pellets in diabetic rats was the highest as 670.01 ± 211.20 lg h/mL, followed by CMC-coated pellets (542.42 ± 116.93), HPMC-coated pellets (539.46 ±189.91), HPMC/carbopol-coated pellets (444.03 ± 90.30),and metformin aqueous solution (199.28 ± 31.07). These data show that the Na-Alg-coated pellets were found to be the best among tested as a new mucoadhesive formulation for metformin hydrochloride prepared by the powder layering technique with a centrifugal fluidizing-granulator.
박은숙 ( Piao Yinshu ),박용애 ( Piao Yongai ) 중국한국(조선)어교육연구학회 2021 한국(조선)어교육연구 Vol.17 No.0
This essay studies Park Jong-Hwa and the image of Yeonsan Gun in his historical novel, Keunmsam-Eue-pee, through analyzing the differences between the historical and the fictional images. Keunmsam-Eue-pee is the first work which depicts Yeonsan Gun different from the historical records. After the Keunmsam-Eue-pee, in the complicated progress of Korean Modern History, Yeonsan Gun frequently appears in various medias such as novels, movies and plays ect., which testifies that the interests in the image of Yeonsan Gun as a common man with psychological complexity and worries are aroused. The novel Keunmsam-Eue-pee describes Yeonsan Gun from three pespectives: the son revenging for his mother, the king abusing power and violence, as well as the man with loneliness, unease and absence of emotion. That is to say, unlike the historically recorded Yeonsan Gun, in Keunmsam-Eue-pee, he is portrayed as a living man true to life. As the novel is composed when the Korea is under the rule of Japanese Imperialism, during that period, the destructive and rebellious image of Yeonsan Gun indirectly reflects the dissatisfactory and resistance against the Japanese Imperialism. In modern society, the reinterpreted image of Yeonsan Gun has renewed meaning that people should value the emotion and communication with others around.