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        Fine mapping of grain weight QTL, tgw11 using near isogenic lines from a cross between Oryza sativa and O. grandiglumis

        Ji‐Min Oh,Sangshetty Balkunde,Paul Yang,Dong‐Beom Yoon,안상낙 한국유전학회 2011 Genes & Genomics Vol.33 No.3

        In our previous study, we reported the grain weight (GW)QTL, tgw11 in isogenic lines derived from a cross between Oryza sativa ssp. Japonica cv. Hwaseong and O. grandiglumis. The O. grandiglumis allele at tgw11 decreased GW in the Hwaseong background. To fine-map tgw11, one F5 plant homozygous for the O. grandiglumis DNA in the target region on chromosome 11 was selected from F_4 line,CR1242 segregating for tgw11 and crossed with Hwaseong to produce secondary F_2 and F_3 populations. QTL analysis using 760 F_2 plants confirmed the existence of tgw11 with an R^2 value of 15.0%. This QTL explained 32.2% of the phenotypic variance for GW in 91 F_3 lines. Substitution mapping with 65 F_3 lines with informative recombination breakpoints in the target region was carried out to narrow down the position of the tgw11. The result indicated that tgw11 was located in the 900-kb interval between two SSR markers, RM224 and RM27358. QTLs for grain width and grain thickness were also located in the same interval suggesting that a single gene is involved in controlling these three traits. Analysis of F3 lines indicated that the variation in TGW is associated with variation in grain shape, specifically grain thickness and grain width. Genetic analysis indicated that the O. grandiglumis allele for small seed was dominant over the Hwaseong allele. SSR markers tightly linked to the GW QTL would be useful in marker-assisted selection for variation in GW in breeding program.

      • 우리나라 치과 기공사의 건강 습관에 영향을 미치는 요인

        오세윤,김웅철,김지환 高麗大學校 倂設 保健大學 保健科學硏究所 1999 保健科學論集 Vol.25 No.1

        This investigation was carried out to evaluate the relations between the levels of health practices and their attributable factors in Korean dental laboratory technicians A questionnaire listing six groups of health practices and their related factors was mailed to randomly selected 1,900 dental laboratory technicians. Among them, 1,344 dental laboratory technicians filled out the questionnaires and returned them. Before the start of main survey, a pilot survey was carried out for validity test of the questionnaire. All the data obtained were corded and analyzed with PC/SAS 6.12 program. The level of inappropriate health practices was the highest in irregular exercise(85.3%), and followed by smoking(61.0%), drinking of alcohol(59.1%), irregular eating habits(45.6%), inappropriate sleep duration(32.2%), and obesity(9.4%). Statistically significant factors by multiple logistic regression analyses were sex. work part in obesity: age. work area. number of employees in hours of sleeping: sex, self assessed health status, health examination, work area, work hours in eating habits: sex, marital status, education in smoking : sex in drinking of alcohol : self assessed health status : health examination, work hours in exercise '. and sex, work hours in health practice index. With the above considerations in mind, the levels of health practices in Korean dental laboratory technicians was relatively low and that was attributable to most of the sociodemographic characteristics, health examination and health status and work history. It is suggested that health promotion programs for promoting self-assessed health status, carrying out health examination, reducing work hours, and measures for elevating the level of health practice of male techinicians be necessary.

      • 와동형태의 설계에 따라 치아에 발생되는 응력의 변화에 관한 연구 : 1. 온레이의 경우

        오세윤,김웅철,김지환 高麗大學校 倂設 保健大學 保健科學硏究所 1994 保健科學論集 Vol.20 No.1

        Because of the anatomical form of posterior teeth, the amount of tooth reduction at the cuspal area in the typical intracoronal cavity will be inevitably maximal, while stress development on the restoration in this area will be relatively minimal. In an attempt to decrease the amount of tooth reduction at the cuspal area, two modified cavities were newly designed in this study. They had a decreased pupal depth of 1mm at the cuspal area and offsets with the depth of 0.5 ~ 1.0mm were formed at the central fossa area. The Von Mises stresses developed in the gold restoratives and in the teeth were compared with that in the typical intracoronal cavity, which had a simple flat pulpal floor with 1.5mm pulpal depth at the central fossa area. Stress analysis was done with two dimensional finite technique. The obtained results were as follows: 1. The newly modified cavity designs were found to be more advantageous in stress distribution. 2. The effect of offset depth was not significant, but some relationship between the offset depth and stress distribution was found.

      • 치과기공사의 직업만족도 측정을 위한 설문도구의 개발

        오세윤,김웅철,김지환,이병기,유진호,김태석,이준석,이주호 高麗大學校 倂設 保健大學 保健科學硏究所 2002 保健科學論集 Vol.28 No.2

        Conflicts between individuals are quite natural and they can act as an positive contributing factor not only to the development of an individual but also to the organization to which one belongs. But too much conflicts will always induce dissatisfaction and stresses, which will be destructive and harmful to all of them, and that is why we are always tying to seek(find) out the causes for the origination of conflicts and remedies to cope with them effectively. The present study, as the first one in a series of studies which our researchers contemplate executing, was designed to develop a measure of job satisfaction for dental laboratory technicians. One job satisfaction measure and two job satisfaction related measures, one for faithfulness for the job and the other for environmental characteristics of dental laboratory were newly developed. The newly developed measures were comprised of a total of 38 items, which were each 12 items for job satisfaction and faithfulness for the job and 14 items for environmental characteristics of dental laboratory With the aid of factor analysis for principal components and categorization of items by panel of professionals, items of each measure were grouped into 2-4 subscales. Contribution to internal consistency was the fina) criterion for an item's inclusion in a subscale. Internal consistency reliability of each item was attested through the statistical analysis on the data obtained from 55 structured questionnaires. Reliability of internal consistency of subscales in each measure of job satisfaction and faithfulness for the job ranged from 0.74 to 0.79 and 0.90-0.91 respectively. The result from this research came to draw the following conclusions. 1. Validity and internal consistency reliability of all the items of each measure was attested. 2. The newly developed measure of job satisfaction was found to be appropriate for (measuring the degree of job satisfaction of) dental technicians, as well as for (other) dental office personnels.

      • 송도 웰빙센터 건립사업 타당성 조사

        윤철현,오세경,강지은 東亞大學校 建設技術硏究所 2008 硏究論文集 Vol.32 No.1

        본 과업의 대상지는 송도 초등학교 내에 위치한 관사부지이다. 이곳을 서구청에서 확보한 예산으로써 서구 주민의 복지를 위한 문화체육시설로 개발할 경우, 그 사업의 타당성 여부를 진단하고 분석하는데 과업의 목적을 두었다. 본 과업은 문화체육센터에 대한 주민의식 및 선호도 파악에 우선 관심을 두었고 서구청 공무원을 조사대상으로 한정하였다. 그 까닭은 공무원 집단은 지역사회 전반에 걸쳐 문제의식이 강하고 가치판단기준이 일반 주민들보다 명확하며 도시 내 주요시설에 대한 식견이 비교적 넓기 때문이다. 본 조사에서 나타난 특징은 첫째, 응답자의 약 85%가 문화체육센터의 수적 부족을 인식한 점이고, 둘째, 45%만이 송도초등학교 내 웰빙센터의 건립에 찬성한 점이다. 반대의 대부분은 일반 주민을 위한 시설이 교육기관과 쉽게 양립 할 수 없다는 것이다. 서구의 인구가 감소한다는 것은 특정시설의 시장여건이 불리해진다는 뜻이다. 이 같은 현실 하에 웰빙센터의 경제적 타당성의 진단에서 나타난 분석결과는 B/C가 1보다 낮고(0.866), 내부수익률 역시 (-)값으로 나타난 점이다. 따라서 송도 웰빙센터 건립사업의 경제적 타당성은 매우 취약하다고 판단된다. 또한 교육청 및 학교당국은 학생중심의 시설건립과 시설 건립 후 교육기관에 기부채납을 요구하고 있으므로 이점이 사업의 결정적인 제약이 되고 있다. 공무원 의식조사에서 나타난 바를 참고할 때 웰빙센터와 같은 문화체육시설은 학교 내가 아닌 인접한 다른 장소에서 적극적으로 건립하는 방안을 모색해 볼 필요가 있다.

      • 당뇨병의 유병기간과 아연 및 구리 영양상태와의 관련성

        윤진숙,오현미,윤지영 啓明大學校 生活科學硏究所 2003 科學論集 Vol.29 No.-

        Literature suggest a relationship between trace elements status and diabetic mellitus. This study was intended to examine the zinc and copper status of diabetic patients. Subjects who participated in this study 79 type H diabetic patients and 77 normal adults. The mean of diabetic duration was 9 years. The mean age of diabetic patients and control group was 57.4 years and 55.2 years, respectively. Zinc and copper intake was measured by food record and food frequency method. Urinary zinc and copper was assessed. There was no significant difference of zinc and copper intake between diabetic patients and control group. Urinary zinc and copper of diabetic patients was significantly higher than control group. It appeared that the longer the diabetic duration, the lower the zinc intake. We concluded that dietary information to increase zinc intake should be included for nutrient education of diabetic patients.

      • 방사선치료를 받은 후두암 환자의 특성 및 치료 결과

        오윤경,장지영,도남용 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1

        Pmpose: To present the characteristics and treatment outcome of laryngeal cancer patients who were treated by radiation therapy with or without surgery and chemotherapy. Materials and Melhods: A total of 23 patients with laryngeal cancer treated from 1998 through 2003 were available for analysis. The primary site of the cancer was the glottis in 12 patients, the supraglottis in 10 patients, and the subglottis in 1 patient. The stages were Ⅰ in 7 patients (30%), Ⅱ in 5(22%), Ⅲ in 3(13%), IV in 6(26%), and recurrent in 2(9%). The minimum follow-up period in surviving patients is 3 years after the radiation therapy. They were treated by radiation therapy at least 44 Gy with or without surgery and chemotherapy. Results: The overall survival at 1, 2, 3, 5 years in total patients were 95.6%, 82.6%, 78.2%, 73.9%. The overall survival at 1, 2, 3, 5 years in the glottic cancer patients were 100%, 100%, 91.6%, 91.6%. The overall survival at 1, 2, 3, 5 years in the supraglottic cancer patients were 90%, 70%, 70%, 60%. The 3-year overall survival showed the significant difference according to the primary site (glottic vs. supraglottic), cervical lymph node status (negative vs. positive), and overall time of radiation therapy (<50 days vs. 50-59 days vs. ≥60 days), Conclusion: The overall survival rate of laryngeal cancer patients in this analysis seems to be similar in early glottic cancers and relatively good in supraglottic cancers as compared with the results of other studies even though the total number of patients is small.

      • 와동형태의 설계에 따라 치아에 발생되는 응력의 변화에 관한 연구 : 인레이의 경우

        오세윤,김웅철,김지환,유진호 高麗大學校 倂設 保健大學 保健科學硏究所 1995 保建科學硏究論集 Vol.4 No.1

        Because of the anatomical form of posterior teeth, the amount of tooth reduction near the marginal ridge area in the typical, widely used intracoronal cavity will be inevitably maximal, while occlusal forces on the restoration in this area will be relatively minimal In an attempt to dicrease the amount of tooth reduction at the marginal ridge area, a modified cavity for inlay with a uniform depth of 15mm, just as in amalgam filling was designed in this study. To analize the stress development in the teeth in that cavity design, 2㎏/㎟ distributive forces were applied on the inlay restoratives and obtained results were compared with that in the typical cavity design which had a flat pulpal wall with a depth of 1.5m at the central fossa area. Analysis was done with two dimensional finite technique. The obtained results were as follows : 1. The patterns of stress distribution and displacement showed no apparent differences. 2. The stress values and the amount of displacement developed, both in inlay cast gold and in the teeth, in the cavity with a uniform depth were less than that in the cavity with a flat pulpal wall. 3. Greatest maximum principle values were concentrated around the interface between the base of inlay body and the teeth.

      • 의예과 학생들의 성격유형검사(MBTI)의 특성

        오윤경,장진영,박상학,류소연 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1

        Pmpose: To investigate the characteristics of Myers-Briggs Type Indicator (MBTI) in premedical students of one medical college and to compare the personality profiles of them with those of other studies which involved the K-orean university students and other country population. Mateiials and Methods: The MBTI was used to measure the personality profiles of premedical students at the Center for Teaching & Leaming of Chosun University. One hundred and twenty five premedical students participated in this study and the MBTI profiles of them were compared to those of K-orean university students (1,441 persons), i.e. their potential patients and those of the United Kingdom (UK.) Population (1,634 persons) and a sample of UK- doctors (313 persons) of one medical college involved in other studies. Results: The premedical students had a preference for Introversion (62%) rather than Extraversion (38%), Sensing (70%) rather than Intuition (30%), Thinking (66%) rather than Feeling (34%), and Judging (57%) rather than Perceiving (43%). There were more Thinking (66% vs 57%, p=0.071) in the premedical students than in K-orean university students with borderline significance. There were significantly more Thinking (66% vs 46%, P=0.000) and more Introversion (62% vs 48%, p=0.002) than in UK- adult population. Also there were significantly more Sensing (62% vs 48%, p=0.002), significantly less Judging (57% vs 68%, P=0.034), and more Introversion (62% vs 53%, 0=0.094) with borderline significance than in UK doctors. But no difference was shown in Thinking between the premedical students and UK- doctors, Conclusion: The personality profiles of the premedical students in this study differed in Thinking with borderline significance from K-orean university students and significantly differed from the UK adult population in Thinking and Introversion showing the cultural difference. No difference of Thinking between the premedical students and UK doctors despite of cultural difference suggests the correlation between the Thinking and medical professional choice.

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