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Ha, Nguyen Thi Hoang,Ha, Nguyen Thi,Nga, Tran Thi Huyen,Minh, Nguyen Ngoc,Anh, Bui Thi Kim,Hang, Nguyen Thi An,Duc, Nguyen Anh,Nhuan, Mai Trong,Kim, Kyoung-Woong Elsevier 2019 Applied geochemistry Vol.108 No.-
<P><B>Abstract</B></P> <P>Phytoremediation is a plant-based, environment-friendly, and cost-effective technology that can be potentially used to remediate contaminated media. This study was conducted to evaluate the phytoextraction and phytostabilization potential, two common techniques of phytoremediation, of 21 plant species growing naturally at the largest tungsten (W) mine in Vietnam—the second largest production of W in the world. The average concentrations in different soil fractions were in the following order: residue > organically complexed, Fe- and Mn oxide-bound > carbonate bound > exchangeable. The total concentrations of arsenic (As), cadmium (Cd), copper (Cu), and zinc (Zn) in the soil varied by 34–3390, 4.87–81.6, 14.3–2080, and 21.9–370 mg/kg, respectively. The concentrations of As, Cd, Cu, and Zn in the shoots ranged 0.71–2400, 0.05–5.55, 4.81–249, and 13.3–380 mg/kg-DW, respectively. The concentrations of As and Cd in all soil samples and Cu in 70% of soil samples collected around the mine fluctuated within 2–227, 3–54, and up to 21-folds higher than the maximum allowable limit for agricultural soils in Vietnam (QCVN 03-MT:2015/BTNMT). The results indicated that hyperaccumulation levels (mg/kg-DW) were obtained for only As in <I>Pityrogramma calomelanos</I> (2400) and <I>Pteris vittata</I> L. (1860). Based on the recorded hyperaccumulation levels, translocation and accumulation factors, biomass, and fast growth of these plants, <I>P. calomelanos</I> and <I>P. vittata</I> were considered to be promising native plants for the phytoextraction of As contaminated soils. <I>Bidens pilosa</I> L. also has great potential for phytostabilization of mining soils contaminated with As and heavy metals.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Soils near multi-metal (W–F–Cu–Au–Bi) mine were contaminated with As, Cd, Cu. </LI> <LI> Arsenic in shoots were in order of Fern > Monocotyledonae > Dicotyledonae. </LI> <LI> <I>Pityrogramma calomelanos</I> and <I>Pteris vittata</I> L. suggested for phytoextraction of As. </LI> <LI> <I>Bidens pilosa</I> L. suggested for the phytostabilization of mining contaminated soils. </LI> </UL> </P>
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Triblock copolymers for nano-sized drug delivery systems
Ngoc Ha Hoang,임채민,심태훈,오경택 한국약제학회 2017 Journal of Pharmaceutical Investigation Vol.47 No.1
Triblock copolymers have been widely used as a material for developing drug delivery systems (DDS). In terms of architecture, triblock copolymers could be classified into symmetric and asymmetric triblock copolymers. Different types of nano-sized structures such as star micelles, flower-like micelles, and polymer vesicles could be prepared from these block copolymers, which would be very potential in delivering various types of agents such as chemical drugs, genes, and contrast agents. Additionally, the nano-sized carriers have been fabricated for environmentally sensitive (pH-sensitive or temperature sensitive) DDS or for enhancing the gene delivery efficiency. Due to their versatility in structures and drug delivery capacity, the application of triblock copolymers would definitely be expanded in near future.
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A novel mathematical modelling for simulating the spread of heavy metals in solid waste landfills
Ngoc Ha Hoang,Anh My Chu,Kim Thai Thi Nguyen,Chi Hieu Le 대한환경공학회 2022 Environmental Engineering Research Vol.27 No.3
Municipal solid waste (MSW) landfills create the environmental pollutions due to problems related to toxins, leachate, and greenhouse gas, which are the growing environmental concerns, especially in developing countries. This paper presents a novel mathematical modelling for simulating the spread of heavy metals in soil layers in the MSW landfills. A new mathematical modelling procedure is studied for deriving the governing equation which describes the time varying concentration of pollutants in the leachate in a 3-dimensional (3D) space of soil layers. A Finite Element Method (FEM) based algorithm is then constructed to solve numerically the governing equation over time in 3D space for effectively analyzing the variation of pollutants concentrations. Finally, the applicability and advantages of the proposed novel method are demonstrated through the case study with soil samples collected from the actual MSW landfill. The successfully developed algorithm can be applied to model and predict the spread of different heavy metals in the MSW landfill sites; and to develop effective solutions and policies for solid waste classification and management, in order to minimise the negative impacts from the potential risk of the toxic heavy metal pollutions, soil contaminations and groundwater pollutions in the areas nearby the MSW landfill.
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Hoa Thi Tran,Giang Thu Nguyen,Hong Ha Thi Nguyen,Huyen Thi Tran,Quang Hong Tran,Quang Ho Tran,Ngoc Thi Ninh,Phat Tien Do,Ha Hoang Chu,Ngoc Bich Pham 한국균학회 2022 Mycobiology Vol.50 No.5
Endophytic fungi are promising sources for the production of podophyllotoxin-an important anticancer compound, replacing depleted medical plants. In this study, the endophytes asso- ciated with Dysosma difformis-an ethnomedicinal plant species were isolated to explore novel sources of podophyllotoxin. Fifty-three endophytic fungi were isolated and identified by morphological observation and ITS-based rDNA sequencing, assigning them to 27 genera in 3 divisions. Fusarium was found the most prevalent genus with a colonization frequency of 11.11%, followed by Trametes (9.26%) and Penicillium (7.41%). Phylogenetic trees were constructed for the endophytic fungi community in two collection sites, Ha Giang and Lai Chau, revealing the adaptation of the species to the specific tissues and habitats. Cytotoxic activity of endophytic fungal extracts was investigated on cancer cell lines such as SK-LU-1, HL-60, and HepG2, demonstrating strong anti-cancer activity of six isolates belonging to Penicillium, Trametes, Purpureocillium, Aspergillus, and Ganoderma with IC50 value of lower than 10 mg/mL. The presence of podophyllotoxin was indicated in Penicillium, Trametes, Aspergillus and for the first time in Purpureocillium and Ganoderma via high-performance liquid chromatography, which implied them as a potential source of this anti- cancer compound.
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Ha-Linh Quach,Thai Quang Pham,Ngoc-Anh Hoang,Dinh Cong Phung,Viet-Cuong Nguyen,Son Hong Le,Thanh Cong Le,Dang Hai Le,Anh Duc Dang,Duong Nhu Tran,Nghia Duy Ngu,Florian Vogt,Cong-Khanh Nguyen 대한의료정보학회 2022 Healthcare Informatics Research Vol.28 No.4
Objectives: Online misinformation has reached unprecedented levels during the coronavirus disease 2019 (COVID-19) pandemic. This study analyzed the magnitude and sentiment dynamics of misinformation and unverified information about public health interventions during a COVID-19 outbreak in Da Nang, Vietnam, between July and September 2020. Methods: We analyzed user-generated online information about five public health interventions during the Da Nang outbreak. We compared the volume, source, sentiment polarity, and engagements of online posts before, during, and after the outbreak using negative binomial and logistic regression, and assessed the content validity of the 500 most influential posts. Results: Most of the 54,528 online posts included were generated during the outbreak (n = 46,035; 84.42%) and by online newspapers (n = 32,034; 58.75%). Among the 500 most influential posts, 316 (63.20%) contained genuine information, 10 (2.00%) contained misinformation, 152 (30.40%) were non-factual opinions, and 22 (4.40%) contained unverifiable information. All misinformation posts were made during the outbreak, mostly on social media, and were predominantly negative. Higher levels of engagement were observed for information that was unverifiable (incidence relative risk [IRR] = 2.83; 95% confidence interval [CI], 1.33–0.62), posted during the outbreak (before: IRR = 0.15; 95% CI, 0.07–0.35; after: IRR = 0.46; 95% CI, 0.34-0.63), and with negative sentiment (IRR = 1.84; 95% CI, 1.23–2.75). Negatively toned posts were more likely to be misinformation (odds ratio [OR] = 9.59; 95% CI, 1.20–76.70) or unverified (OR = 5.03; 95% CI, 1.66–15.24). Conclusions: Misinformation and unverified information during the outbreak showed clustering, with social media being particularly affected. This indepth assessment demonstrates the value of analyzing online “infodemics” to inform public health responses.
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Factors Affecting the Internal Control System: A Case Study of Chemical Enterprises in Vietnam
Hoang Thanh NGO,Tung Dao NGUYEN,Nga Thuy Thi NGUYEN,Ha Ngoc DAO,Anh Phuong Tran VU 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.12
The article analyzes the impact of factors affecting the internal control system of chemical enterprises in Vietnam, providing more empirical evidence on factors affecting the system of internal control. Research data is collected in the form of face-to-face interviews and email interviews with managers and employees working in different positions, managers at all levels, chief accountants, and accountants of 52 chemical enterprises in Vietnam. The survey results collected 310 questionnaires. After eliminating the invalid questionnaires due to many blank cells, the authors chose to use 297 questionnaires. Quantitative research was carried out with SPSS 25 software. Research results show that Business Strategy, Organizational Structure, Organization’s perception of the instability of the external environment, and Organizational culture are the factors that positively affect the internal control system of chemical enterprises. This can be explained that, for chemical enterprises, Business strategy, Organizational structure, Organization’s perception of the instability of the external environment, and Good organizational culture will positively impact the internal control system of chemical enterprises. Based on the research results, the authors have proposed recommendations to enhance the effectiveness of the internal control system of chemical enterprises in Vietnam, thereby contributing to improving the performance of enterprises in the chemical Vietnamese.
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Tran Ha Thi Thanh,Dang Anh Kieu,Ly Duc Viet,Vu Hao Thi,Hoang Tuan Van,Nguyen Chinh Thi,Chu Nhu Thi,Nguyen Vinh The,Nguyen Huyen Thi,Truong Anh Duc,Pham Ngoc Thi,Dang Hoang Vu 아세아·태평양축산학회 2020 Animal Bioscience Vol.33 No.10
Objective: The rapid and reliable detection of the African swine fever virus (ASFV) plays an important role in emergency control and preventive measures of ASF. Some methods have been recommended by FAO/OIE to detect ASFV in clinical samples, including real-time polymerase chain reaction (PCR). However, mismatches in primer and probe binding regions may cause a false-negative result. Here, a slight modification in probe sequence has been conducted to improve the qualification of real-time PCR based on World Organization for Animal Health (OIE) protocol for accurate detection of ASFV in field samples in Vietnam. Methods: Seven positive confirmed samples (four samples have no mismatch, and three samples contained one mutation in probe binding sites) were used to establish novel real-time PCR with slightly modified probe (Y = C or T) in comparison with original probe recommended by OIE. Results: Both real-time PCRs using the OIE-recommended probe and novel modified probe can detect ASFV in clinical samples without mismatch in probe binding site. A high correlation of cycle quantification (Cq) values was observed in which Cq values obtained from both probes arranged from 22 to 25, suggesting that modified probe sequence does not impede the qualification of real-time PCR to detect ASFV in clinical samples. However, the samples with one mutation in probe binding sites were ASFV negative with OIE recommended probe but positive with our modified probe (Cq value ranked between 33.12-35.78). Conclusion: We demonstrated for the first time that a mismatch in probe binding regions caused a false negative result by OIE recommended real-time PCR, and a slightly modified probe is required to enhance the sensitivity and obtain an ASF accurate diagnosis in field samples in Vietnam.
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Influence of Corporate Governance on Dividend Policy in Vietnam
NGUYEN, Ha Viet,DANG, Hung Ngoc,DAU, Hung Hoang Korea Distribution Science Association 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.2
The paper examines the impact of corporate governance (CG), on dividend policy (DP) of enterprises in Vietnam. The paper studies the impact of CG on DP of businesses listed on Vietnam's stock exchange in the period 2008-2018 with 2,937 observations. The data of these companies is collected from the financial statements of businesses and Vietstock data sets, as well as aggregated from the data published on some reputable securities websites. The study used GLS regression method for data collected at listed companies in Vietnam in the period of 2008-2018. The research results have found that CG, the chairman of the board of directors (BOD), and the managing director have a negative effect on the DP. Specifically, companies with strong BODs tend to pay low dividends. At the same time, research shows that factors such as profitability, financial leverage, firm size, and investment opportunities affect DP. This result underscores the importance of corporate governance (both internal and external) to the income distribution decision and provides policy implications for investors and company executives. The study finds solid evidence that alternative theory explains better the relationship between corporate governance and dividend policy. Accordingly, companies with weak corporate governance will pay more dividends.
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