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Dong Van VU1,Tai Van PHAM2,Ghi Nha TRAN3,Anh Phuong Thi NGUYEN4,Cong Van NGUYEN5 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.6
This study seeks to examine the relationship between business resources (through VRIN: Valuable - valuable, Rare - scarce; Inimitable - difficult to adapt, Irreplaceable - hard to replace), dynamic capability, external cooperation, and efficiency of startups operating in the seafood export sector. Research data was collected randomly and conveniently from 250 enterprises in Ba Ria-Vung Tau province, Vietnam, from October 2020 to December 2020. After excluding those ineligible, the remaining 204 enterprises meet the research conditions. With the support of SPSS-AMOS 22 dedicated software, using the 5-step Likert scale and Structural Equation Modeling (SEM), the study conducted analysis steps such as verifying convergence, discriminant value, unidirectional and scale reliability when giving the components correlated freely in the critical model by Confirmatory Factor Analysis (CFA) analysis. Results of the study have shown that the enterprise resource factor - VRIN has a positive impact on dynamic capability, and outside cooperation. However, in contrast to previous studies, we found that the relationship between enterprise resources - VRIN and performance as well as the relationship between dynamics capacity and performance is not clear. This shows that seafood exporters need to promote, exploit and effectively use this precious resource to improve business efficiency.
Hieu, Doan Thanh,Anh, Duong Tien,Tuan, Nguyen Minh,Hai, Pham-The,Huong, Le-Thi-Thu,Kim, Jisung,Kang, Jong Soon,Vu, Tran Khac,Dung, Phan Thi Phuong,Han, Sang-Bae,Nam, Nguyen-Hai,Hoa, Nguyen-Dang Elsevier 2018 Bioorganic chemistry Vol.76 No.-
<P><B>Abstract</B></P> <P>In our search for novel small molecules targeting histone deacetylases, we have designed and synthesized several series of novel <I>N</I>-hydroxybenzamides/<I>N</I>-hydroxypropenamides incorporating quinazolin-4(3<I>H</I>)-ones (<B>4a-h</B>, <B>8a-d, 10a-d)</B>. Biological evaluation showed that these hydroxamic acids were generally cytotoxic against three human cancer cell lines (SW620, colon; <I>PC</I>-3, prostate; NCI-H23, lung cancer). It was found that the <I>N</I>-hydroxypropenamides (<B>10a-d)</B> were the most potent, both in term of HDAC inhibition and cytotoxicity. Several compounds, e.g. <B>4e</B>, <B>8b-c</B>, and <B>10a-c</B>, displayed up to 4-fold more potent than SAHA (suberoylanilide hydroxamic acid, vorinostat) in term of cytotoxicity. These compounds also comparably inhibited HDACs with IC<SUB>50</SUB> values in sub-micromolar range. Docking experiments on HDAC2 isozyme revealed some important features contributing to the inhibitory activity of synthesized compounds, especially for propenamide analogues. Importantly, the free binding energy computed was found to have high quantitative correlation (<I>R</I> <SUP>2</SUP> ∼ 95%) with experimental results.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Novel quinazolin-4(3H)-one-based <I>N</I>-hydroxybenzamides/<I>N</I>-hydroxypropenamides were synthesized. </LI> <LI> The <I>N</I>-hydroxybenzamides/<I>N</I>-hydroxypropenamides exhibited potent HDAC inhibition. </LI> <LI> The <I>N</I>-hydroxybenzamides/<I>N</I>-hydroxypropenamides exhibited good cytotoxicity. </LI> <LI> Docking studies and ADMET estimation were carried out. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>Two series of novel, simple <I>N</I>-hydroxybenzamides/<I>N</I>-hydroxypropenamides incorporating quinolin-4(3H)-one (<B>4a-h</B>, <B>8a-d, 10a-d</B>) were designed and synthesized. Biological evaluation showed that these benzamides/propenamides potently inhibited HDAC with IC<SUB>50</SUB> values in sub-micromolar range. A number of compounds also exhibited cytotoxicity up to 4-fold more potent than SAHA, a positive control.</P> <P>[DISPLAY OMISSION]</P>
Factors Affecting the Internal Control System: A Case Study of Chemical Enterprises in Vietnam
Hoang Thanh NGO,Tung Dao NGUYEN,Nga Thuy Thi NGUYEN,Ha Ngoc DAO,Anh Phuong Tran VU 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.12
The article analyzes the impact of factors affecting the internal control system of chemical enterprises in Vietnam, providing more empirical evidence on factors affecting the system of internal control. Research data is collected in the form of face-to-face interviews and email interviews with managers and employees working in different positions, managers at all levels, chief accountants, and accountants of 52 chemical enterprises in Vietnam. The survey results collected 310 questionnaires. After eliminating the invalid questionnaires due to many blank cells, the authors chose to use 297 questionnaires. Quantitative research was carried out with SPSS 25 software. Research results show that Business Strategy, Organizational Structure, Organization’s perception of the instability of the external environment, and Organizational culture are the factors that positively affect the internal control system of chemical enterprises. This can be explained that, for chemical enterprises, Business strategy, Organizational structure, Organization’s perception of the instability of the external environment, and Good organizational culture will positively impact the internal control system of chemical enterprises. Based on the research results, the authors have proposed recommendations to enhance the effectiveness of the internal control system of chemical enterprises in Vietnam, thereby contributing to improving the performance of enterprises in the chemical Vietnamese.