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Tran, Quang-Vinh,Kim, Won-Ho,Shin, Jin-Ho,Baek, Woon-Bo Korean Institute of Intelligent Systems 2010 INTERNATIONAL JOURNAL of FUZZY LOGIC and INTELLIGE Vol.10 No.2
This paper proposed an ECAM (Electronic cam) control system which has simple and general structure. The proposed cam controller adopted the linear and polynomial curve-fitting method to generates a smooth cam profile curve function. Smooth motion trajectory of master actuator guarantees the good performance of slave motion and has an important effect on the interpolation quality of ECAM. The auto-tuning PID velocity controller was applied to overcome the uncertainties in ECAM, and the gains of the controller are updated continuously to ensure the consistency of system performance under varying working conditions. The robustness of system against the varying load torque disturbances and noises is guaranteed by using the load torque disturbance observer to suppress the disturbance on master actuator. The velocity compensator was applied to compensate the degradation of performance of slave motion caused from the varying driving speed of master motion. The stability and validity of the proposed ECAM control system was verified by simulation results.
Quang-Vinh Tran,Won-Ho Kim,Jin-Ho Shin,Woon-Bo Baek 한국지능시스템학회 2010 INTERNATIONAL JOURNAL of FUZZY LOGIC and INTELLIGE Vol.10 No.2
This paper proposed an ECAM (Electronic cam) control system which has simple and general structure. The proposed cam controller adopted the linear and polynomial curve-fitting method to generates a smooth cam profile curve function. Smooth motion trajectory of master actuator guarantees the good performance of slave motion and has an important effect on the interpolation quality of ECAM. The auto-tuning PID velocity controller was applied to overcome the uncertainties in ECAM, and the gains of the controller are updated continuously to ensure the consistency of system performance under varying working conditions. The robustness of system against the varying load torque disturbances and noises is guaranteed by using the load torque disturbance observer to suppress the disturbance on master actuator. The velocity compensator was applied to compensate the degradation of performance of slave motion caused from the varying driving speed of master motion. The stability and validity of the proposed ECAM control system was verified by simulation results.
Hoa Thi Tran,Giang Thu Nguyen,Hong Ha Thi Nguyen,Huyen Thi Tran,Quang Hong Tran,Quang Ho Tran,Ngoc Thi Ninh,Phat Tien Do,Ha Hoang Chu,Ngoc Bich Pham 한국균학회 2022 Mycobiology Vol.50 No.5
Endophytic fungi are promising sources for the production of podophyllotoxin-an important anticancer compound, replacing depleted medical plants. In this study, the endophytes asso- ciated with Dysosma difformis-an ethnomedicinal plant species were isolated to explore novel sources of podophyllotoxin. Fifty-three endophytic fungi were isolated and identified by morphological observation and ITS-based rDNA sequencing, assigning them to 27 genera in 3 divisions. Fusarium was found the most prevalent genus with a colonization frequency of 11.11%, followed by Trametes (9.26%) and Penicillium (7.41%). Phylogenetic trees were constructed for the endophytic fungi community in two collection sites, Ha Giang and Lai Chau, revealing the adaptation of the species to the specific tissues and habitats. Cytotoxic activity of endophytic fungal extracts was investigated on cancer cell lines such as SK-LU-1, HL-60, and HepG2, demonstrating strong anti-cancer activity of six isolates belonging to Penicillium, Trametes, Purpureocillium, Aspergillus, and Ganoderma with IC50 value of lower than 10 mg/mL. The presence of podophyllotoxin was indicated in Penicillium, Trametes, Aspergillus and for the first time in Purpureocillium and Ganoderma via high-performance liquid chromatography, which implied them as a potential source of this anti- cancer compound.
Quang, Tran Hong,Ngan, Nguyen Thi Thanh,Minh, Chau Van,Kiem, Phan Van,Nhiem, Nguyen Xuan,Tai, Bui Huu,Thao, Nguyen Phuong,Luyen, Bui Thi Thuy,Song, Seok-Bean,Kim, Young-Ho Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.11
A new compound, kalopanaxin F (3), and 11 known compounds (1, 2, 4-12), were isolated from the stem bark of Kalopanax pictus. Their structures were elucidated on the basis of chemical and spectroscopic methods. Five of the compounds (2, 3, 5, 6, and 12) significantly inhibited $TNF{\alpha}$-induced NF-${\kappa}B$ transcriptional activity in HepG2 cells in a dose-dependent manner, with $IC_{50}$ values ranging from 6.2 to 9.1 ${\mu}M$. Furthermore, the transcriptional inhibitory function of these compounds was confirmed based on decreases in COX-2 and iNOS gene expression in HepG2 cells. Compounds 3-7, 9, and 12 significantly activated the transcriptional activity of PPARs dose-dependently, with $EC_{50}$ values ranging from 4.1-$12.7{\mu}M$. Compounds 4 and 5 exhibited $PPAR{\alpha}$, $PPAR{\gamma}$, and $PPAR{\beta}({\delta})$ transactivational activities in a dose-dependent manner, with $EC_{50}$ values of 16.0 and 17.0, 8.7 and 16.5, 26.2 and 26.3 ${\mu}M$, respectively.
α-Glucosidase Inhibitors from the Roots of Sophora flavescens
Quang, Tran Hong,Ngan, Nguyen Thi Thanh,Minh, Chau Van,Kiem, Phan Van,Tai, Bui Huu,Thao, Nguyen Phuong,Kwon, Se-Uk,Lee, Young-Mi,Kang, Hee-Kyoung,Kim, Young-Ho Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.5