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8.3% Carbamide Peroxide 함유 펜 형 자가미백제인 BIancTis Forte의 색조개선 및 안전성에 관한 임상연구
이진경,민선홍,홍성태,오소람,정신혜,황영혜,유성엽,배광식,백승호,이우철,손원준,금기연 대한치과보존학회 2009 Restorative Dentistry & Endodontics Vol.34 No.2
This clinical study evaluated the whitening effect and safety of polymer based-pen type BlancTis Forte(NIBEC) containing 8.3% carbamide peroxide. Twenty volunteers used the BlancTis Forte whitening agent for 2 hours twice a day for 4 weeks As a control. Whitening Effect Pen (LG) containing 3% hydrogen peroxide was used by 20 volunteers using the same protocol. The change in shade (ΔE^(*) color difference) was measured using Shadepilot™ (DeguDent) before, during and after bleaching (2 weeks, 4 weeks and postbleaching 4 weeks). A clinical examination for any side effects (tooth hypersensitivity or soft tissue complications) was also performed at each check-up. The following results were obtained. 1 Both the experimental and control groups displayed a noticeable change in shade (ΔE) of over 2 No significant differences were found between the two group (p>0.05) implying that the two agents have a similar whitening effect. 2 The whitening effect was mainly due to changes in a and b values rather than in L value (brightness). The experimental group showed a significantly higher change in b value thus yellow shade than the control(p < 0.05) 3 None of the participants complained of tooth hypersensitivity or soft tissue complications confirming the safety of both whitening agents 8.3%의 carbamide peroxide를 함유한 펜형 코팅용 미백제인 BlancTis Forte (NIBEC, Seosul & JinCheon)를 실험군으로, 3% hydrogen peroxide를 함유한글 Whitening Effect Pen (LG. Seoul) 제재를 대조군으로 각각 피험자 20명에게 2시간씩 1일 2회 제조사의 지시대로 치아표면에 4주간 적용하도록 지시하고 색조개선 효능과 안전성을 평가하였다. 미백 효과는 미백 전 및 미백 2주, 4주 및 미백 종료 4주 후에 Shadopilot™을 이용하여 색 변화를 측정하였고, 매 내원시기마다 모든 환자는 치수생활력 검사와 치주 및 치태 검사를 통해 부작용 여부 (치아과민증 및 구감 내 연조직의 부작용)를 기록한 후 다음과 같은 결과를 얻었다. 1.실험군 및 대조군의 색 변화량 (ΔE)은 2이상으로 인지할 수 있는 색 변화를 보였으며, 두 제품 간에는 통계적으로 유의한 차이를 보이지 않아 (p > 0.05) 유사한 미백효능을 나타냄을 알 수 있었다. 2,미백효과는 명도의 개선보다는 주로 a. b값의 변화에 의한 것으로 특히 실험군에서 b값의 변화, 즉 황색조의 개선효과가 대조군에 비해 유의성 있게 높은 것으로 나타났다 (p <0.05). 3.치아나 치은의 과민증이나 이상증상을 호소하는 피험자는 없어 두 제품 모두 안전성을 확인할 수 있었다.
( Eun Jong Song ),( Sae Mi Park ),( Hye Rim Ko ),( Dae Hong Kim ),( Kum Hee Jung ),( Young Bok Lee ),( Dong Soo Yu ),( Jin Wou Kim ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2
Background: Balneotherapy is considered to have therapeutic properties for psoriasis, however the immunologic mechanism of balenotherapy is not established. Objectives: A imiquimod-induced psoriasis model was used for evaluating the therapeutic effects of balneotherapy with Ul-Jin (Baek-Am) thermomineral water. Methods: Clinical improvements were evaluated using modified SCORAD index. Confocal microscopic imaging analysis was performed for lesional expression of IL-17, CD-4, Foxp3, and TNF-a. Lesional mRNA expression of IL-17, IL-15, IL-6, and Foxp3 was evaluated by real-time reverse transcriptase polymerase chain reaction method. Histologic evaluation was also performed. Results: balneotherapy with Ul-Jin (Baek-Am) thermomineral water showed immunomodulatory effects in psoriasis-like murine model by decreasing inflammatory cytokines and increasing lesional regulatory helper T cells. Conclusion: These results suggest that balneotherapy can be an effective and safe treatment option in psoriasis.
( Hye Rim Ko ),( Sae Mi Park ),( Dae Hong Kim ),( Eun Jong Song ),( Kum Hee Jung ),( Jin Wou Kim ),( Dong Soo Yu ),( Young Bok Lee ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2
Background: A novel injectable filler of polymethylmethacrylate and cross-linked dextran in hydroxypropyl methylcellulose was introduced in commercial filler market. Objectives: For soft tissue augmentation, the safety and biocompatibility should be evaluated and the stability at the implantation site should be assessed by histologic evaluation. Methods: Polymethylmethacrylate and cross-linked dextran in hydroxypropyl methylcellulose was subcutaneously injected into the skin of Spragu-Dawly Rats. Histologic evaluation was performed at 13 weeks and 12 months after the injection. Inflammatory cell infiltration, neovascularization, and fibrosis were scored with grading systems. Results: The mean score of histologic evaluation was 5.7 and 3.9 at 13 weeks and 12 months, respectively. Polymethylmethacrylate and cross-linked dextran in hydroxypropyl methylcellulose was kept in place through fine fibrous capsules at 12 months after injections. Conclusion: The mixture of polymethymetahcrylate and cross-linked dextran in hydroxyproly methylcellulose can be safe material for soft tissue augmentation with more than 12-month longevity.
장중첩증으로 발현한 회장 말단의 외투 세포 림프종 1예
유금혜 ( Kum Hei Ryu ),심기남 ( Ki Nam Shim ),송현주 ( Hyun Joo Song ),나윤주 ( Yoon Ju Na ),백수정 ( Su Jung Baik ),윤수진 ( Su Jin Yoon ),정해선 ( Hae Sun Jung ),염혜정 ( Hye Jung Yeom ),정성애 ( Sung Ae Jung ),김태헌 ( Tae Hun 대한장연구학회 2006 Intestinal Research Vol.4 No.1
Although the gastrointestinal tract is one of the major sites of primary extranodal malignant lymphoma, the colon and small bowel are less frequently involved than the stomach. Mantle cell lymphoma comprising only 6% of the malignant non-Hodgkin lymphomas. Mantle cell lymphoma usually distributes from the esophagus to rectum, with advanced stages of peripheral lymphadenopathy, splenomegaly, and bone marrow infiltration. We report a case of ileocolic intussusception due to ileal mantle cell lymphoma. (Intestinal Research 2006;4:61-63)
Kwon, Na Hye,Jang, Young Jae,Kim, Dong Wook,Shin, Dong Oh,Kim, Kum Bae,Kim, Jin Sung,Choi, Sang Hyoun Korean Society of Medical Physics 2020 의학물리 Vol.31 No.4
This study investigated and analyzed the Korean and international status of radioactive waste management for medical linear accelerators (linacs) and proceed prior research to suggest radiation safety regulations and guidelines for the safe use of radiation. We analyzed the number of linacs installed in the radiation oncology departments of 103 institutions. In addition, we analyzed the procedures and standards for disposal in Korea and foreign countries. For foreign countries, we analyzed the status based on reports from the United States, Japan, Europe, and Canada. A total of 182 linacs are installed in Korea and 95% of them use more than 10 MV of energy. In Korea, standards for managing radioactive waste from a linac, disposal procedures, and clearance criteria have yet to be established. Therefore, radioactive waste is disposed of in different ways depending on the hospitals where they originate. Japan, the US, and Canada have recommended clearance levels and procedures for linacs. Other countries have provided management guidelines for research or large-scale accelerators, but not for medical purposes. In this study, we investigated the management of radioactive waste from medical linacs in Korea and abroad. Several foreign countries have suggested a clearance level and criteria for disposing of waste storage drums. For the safe management of medical linacs, it is necessary to establish safety management regulations. In Korea, standards for disposal, such as radiation or dose limits, are required for medical linacs. A system for clearance when disposing at a medical institution should be created.