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Plyometric Training과 비타민 C 투여가 남고생의 체력, 혈중 젖산, 암모니아 및 젖산탈수소효소에 미치는 영향
장준원,김세종,이현미,서혜림,조현숙,고정림,염종우,예정복,백영호 釜山大學校 附設 體育科學硏究所 2003 體育科學硏究所 論文集 Vol.19 No.-
The purpose of this was to examine the effect of plyometric training and vitamin C ingestion on physical fitness and fatigue substance....
P148 : A clinical study of skin diseases on vulvar
( Hye Rim Ko ),( So Min Kim ),( Chae Young Won ),( Hyung Jin Hahn ),( Young Bok Lee ),( Jin Wou Kim ),( Dong Soo Yu ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2
Background: Vulvar diseases are not rare in dermatology, however the clinical investigations of the vulvar lesions are insufficient. Objectives: The purpose of this study was to investigate the epidemiological aspects of the vulvar diseases, and to highlight the clinical features of dermatoses of the vulvar with the brief review of the common vulvar diseases. Methods: The retrospective clinical study was performed by reviewing charts, pathologic slide, and clinical photographs of 37 patients who had received skin biopsy for vulvar lesions at Uijeongbu St. Mary’s Hospital between February 2009 and September 2013. Results: The mean age was 47.3 years. The most frequent vulvar diseases were epidermal cyst, lichen sclerosus, lichen simplex chronicus, herpes simplex infection and condyloma accuminatum in the decreasing order of frequency. Except for the 11 asymptomatic patients, the rest of the patients complained of various symptoms such as a pain, prickling sensation, tenderness and pruritus. Of the 37 cases, 14 had patches or plaques, 11 had papules or nodules, 6 had erosions or ulcers and 6 had vulvar mass. Conclusion: We retrospectively studied 37 cases of vulvar diseases. The results of this study are similar to previousreports on the clinical features of vulvar diseases. This study suggests that various conditions can affect the vulvar. Further investigation with a larger group of patients is necessary to better understand the epidemiology of vulvar diseases.
( Hye Rim Ko ),( Sae Mi Park ),( Dae Hong Kim ),( Eun Jong Song ),( Kum Hee Jung ),( Jin Wou Kim ),( Dong Soo Yu ),( Young Bok Lee ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2
Background: A novel injectable filler of polymethylmethacrylate and cross-linked dextran in hydroxypropyl methylcellulose was introduced in commercial filler market. Objectives: For soft tissue augmentation, the safety and biocompatibility should be evaluated and the stability at the implantation site should be assessed by histologic evaluation. Methods: Polymethylmethacrylate and cross-linked dextran in hydroxypropyl methylcellulose was subcutaneously injected into the skin of Spragu-Dawly Rats. Histologic evaluation was performed at 13 weeks and 12 months after the injection. Inflammatory cell infiltration, neovascularization, and fibrosis were scored with grading systems. Results: The mean score of histologic evaluation was 5.7 and 3.9 at 13 weeks and 12 months, respectively. Polymethylmethacrylate and cross-linked dextran in hydroxypropyl methylcellulose was kept in place through fine fibrous capsules at 12 months after injections. Conclusion: The mixture of polymethymetahcrylate and cross-linked dextran in hydroxyproly methylcellulose can be safe material for soft tissue augmentation with more than 12-month longevity.
( Hye-rim Jung ),( Ju-hee Lee ),( Yu-mi Moon ),( Tae-rim Choi ),( Soo-yeon Yang ),( Hun-suk Song ),( Jun Young Park ),( Ye Lim Park ),( Shashi Kant Bhatia ),( Ranjit Gurav ),( Byoung Joon Ko ),( Yung- 한국미생물생명공학회(구 한국산업미생물학회) 2019 Journal of microbiology and biotechnology Vol.29 No.5
Polyhydroxybutyrate (PHB), the most well-known polyhydroxyalkanoate, is a bio-based, biodegradable polymer that has the potential to replace petroleum-based plastics. Lignocellulose hydrolysate, a non-edible resource, is a promising substrate for the sustainable, fermentative production of PHB. However, its application is limited by the generation of inhibitors during the pretreatment processes. In this study, we investigated the feasibility of PHB production in E. coli in the presence of inhibitors found in lignocellulose hydrolysates. Our results show that the introduction of PHB synthetic genes (bktB, phaB, and phaC from Ralstonia eutropha H16) improved cell growth in the presence of the inhibitors such as furfural, 4-hydroxybenzaldehyde, and vanillin, suggesting that PHB synthetic genes confer resistance to these inhibitors. In addition, increased PHB production was observed in the presence of furfural as opposed to the absence of furfural, suggesting that this compound could be used to stimulate PHB production. Our findings indicate that PHB production using lignocellulose hydrolysates in recombinant E. coli could be an innovative strategy for cost-effective PHB production, and PHB could be a good target product from lignocellulose hydrolysates, especially glucose.
Lyme disease presenting with erythema migrans: case report
( Hye Rim Ko ),( Sae Mi Park ),( Hyung Jin Hahn ),( Young Bok Lee ),( Dong Soo Yu ),( Jin Wou Kim ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1
Lyme disease is an infectious condition caused by an exposure to a tick bite containing spirochetes, most notably Borrelia burdorferi. Lyme borreliosis typically begins with an erythematous rash termed erythema migrans, but clinical manifestations include not only dermatologic findings, but also potential cardiac, neurologic findings and arthritis. Most of the cases of Lyme disease have occurred in the United States and Europe, and far fewer cases have occurred in Asia. A 55-year-old women presented with asymptomatic, solitary, 0.3 cm-sized, brownish tick with peripheral erythema on the Lt. axilla detected on the morning of visit to the clinic. There were no extracutaneous symptoms such as arthralgia, fever or malaise. Physical examination, including cardiovascular and neurologic examination, was otherwise normal. Histopathologic findings revealed focal epidermal necrosis and homogenous collagen. Perivascular Infiltration by lymphocytes and neutrophils were also seen. The erythematous patch expanded centrifugally to 15 cm in diameter over three weeks. The patient was diagnosed with lyme disease and was accordingly treated with doxycycline. Herein, we report a case of lyme disease presenting with erythema migrans in a 55-year-old female
Lichen striatus following Blaschko lines
( Hye Rim Ko ),( Ji Won Yun ),( Hyung Jin Hahn ),( Young Bok Lee ),( Dong Soo Yu ),( Jin Wou Kim ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1
Lichen striatus is an uncommon self-limiting dermatosis that occurs mostly in children and rarely in adults. It presents as linear, erythematous, lichenoid papules distributed along Blaschko lines usually on the extremities and rarely on the trunk and face. It is important to distinguish lichen striatus from many conditions following Blaschko lines, particularly the adult “blaschkitis” initially described as a distinct entity from lichen striatus. Blaschkitis is more common in adults, consists of papules and vesicles in multiple lines usually on the trunk, is more recurrent, and histologically shows a spongiotic rather than a lichenoid pattern. However, it is still not clear whether lichen striatus and blaschkitis are two distinct diseases or variations of the same entity. A 45-year-old male presented with pruritic, linear, brownish papules on the back for 1 month. The lesions showed the pattern of a v on the spine, suggesting the distribution along Blaschko lines. Histopathological findings showed minimal spongiosis and lichenoid lymphohistiocytic infiltrates in the upper dermis and around the sweat ducts in the deep dermis. After 6 months, the lesions improved with topical steroid preparations although pigmentation persisted. The clinical features and histologic findings suggested the diagnosis of lichen striatus. Herein, we report a case of lichen striatus distributed along Blaschko lines on a trunk in an adult patient.
단기 창업교육프로그램의 효과분석: D대학교 창업동아리를 중심으로
고혜림(Hye Rim Ko),홍창남(Chang Nam Hong) 한국지방교육경영학회 2016 지방교육경영 Vol.19 No.1
본 연구는 창업교육의 양적 성장에 따른 교육의 질적 효과를 알아보기 위한 연구이다. 단기 창업교육프로그램의 효과를 분석한 결과는 다음과 같다. 첫째, 이론수업 위주의 프로그램보다는 직접 체험할 수 있는 실습형 프로그램이 더 높은 만족도와 교육성과를 보였다. 둘째, 학생의 창업의지와 자기효능감이 창업교육프로그램 참여 이전과 이후에 어떻게 달라졌는지 분석한 결과 창업의지는 통계적으로 유의미한 차이가 나타나지 않았으며, 자기효능감은 통계적으로 유의미한 차이를 나타냈다. 이러한 연구결과는 효과적인 창업교육프로그램을 개발할 수 있는데 영향을 미칠 것이다. This study is to research the qualitative effect of education in accordance with quantitative growth of start=up education. The outcome to analyze the effect of short-term start-up education program which this study intends to research is as follows. First, actual experience program shows higher satisfaction than theory centered program. The performance of education of practice type program also shows higher same as the education satisfaction. Second, as a result of analyzing how different the commitment of entrepreneurship, self-efficacy of student are before and after participation of start=up education program, the commitment of entrepreneurship didn`t show the meaningful difference statistically, the self-efficacy shows the meaningful difference statistically. To research the start-up education program in D university currently, we can find that the start-up education which can enhance the self-efficacy but the education in which we can elevate the commitment of entrepreneurship is not conducted through start-up education. It is assumed that actual founders are not many compared to the activation of start-up education for its reason. It is considered many programs which can elevate the commitment of entrepreneurship should be developed for the future start up education program.
눈꺼풀 피부 악성 종양의 모즈 미세도식 수술 후 결손부의 복원
고혜림 ( Hye Rim Ko ),민정아 ( Jung Ah Min ),이영복 ( Young Bok Lee ),한형진 ( Hyung Jin Hahn ),김진우 ( Jin Wou Kim ),유동수 ( Dong Soo Yu ) 대한피부과학회 2014 大韓皮膚科學會誌 Vol.52 No.12
Background: The reconstruction of eyelid defects is extremely complex because both functional and aesthetic aspects should be considered. Numerous techniques for reconstruction are available for repairing eyelid defects, depending on the size, location, and extent of the defect. Objective: This study was aimed at assessing the effectiveness and cosmetic consequences of various reconstruction techniques for eyelid defects after Mohs micrographic surgery. Methods: Twenty patients who received a diagnosis of skin cancer of the eyelids from November 2005 to August 2009 were analyzed. Among them, 15 patients were treated with a local flap to reconstruct the defective eyelids, and the remaining patients were treated with primary closure. The medical records and photographs were reviewed by two independent physicians, and postoperative results were evaluated. Results: Eyelid defects were reconstructed with various surgical techniques, such as primary closure, transposition flap, subcutaneous island pedicle flap, advancement flap, rotation flap, Tenzel flap, and hard palate mucous membrane graft. The cosmetic results were satisfactory, and 16 of 20 (80%) patients showed good to excellent results. However, one patient developed a sclera show and another patient showed tumor recurrence. Conclusion: Many reconstruction techniques can be used for eyelid defects. An optimal choice would be one that is based on the extent, depth, and location of the defect; skin condition and wishes of the patient; and the surgeon’s experience. Furthermore, it is important to have an understanding of the anatomy of the eyelid, the basic principles of the reconstruction techniques, and the merits and drawbacks of each technique. (Korean J Dermatol 2014; 52(12):864∼872)