http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Chu, Jia-Qi,Kim, Su-Mi,Lee, Kwang-Nyeong,Oem, Jae-Ku,Ko, Young-Joon,Lee, Hyang-Sim,Kim, Yong-Joo,Park, Jee-Yong,Kim, Kwang-Jae,Parida, Satya,Oh, Yooni,Paton, David J.,Joo, Yi-Seok,Kim, Byounghan,Park, The Korean Society for Microbiology 2012 Journal of Bacteriology and Virology Vol.42 No.3
Interferon is an important cytokine that plays a critical role in the initial host defense against viral infection. Recombinant human adenoviruses expressing human interferon-${\alpha}$ (Ad-$HIFN{\alpha}$) or pig interferon-${\beta}$ fused with interleukin-18 (Ad-$PIFN{\beta}$-IL18) were constructed and used to induce an early protective response against foot and mouth disease (FMD). To analyze the antiviral effect, bovine thyroid and porcine kidney IBRS-2 cells and ICR mice were treated with Ad-$HIFN{\alpha}$, Ad-$PIFN{\beta}$-IL18, and cocktail of Ad-$HIFN{\alpha}$ and Ad-$PIFN{\beta}$-IL18. The survival rate of suckling mice was monitored after foot and mouth disease virus (FMDV) challenge following intra-peritoneal (IP) administration of appropriate adenovirus. Indirect antigen ELISA was performed to evaluate inhibition of FMDV replication following challenge with the FMDV O, A, or Asia 1 serotypes in vitro. These recombinant adenoviruses reduced the replication of FMDV in susceptible cells, thereby decreasing the fatality in mice, suggesting that they can be a useful control method for the early protection against FMD infection in livestock after field trial.
한국노인약물역학코호트에서 폐암 발생률, 사망률 및 생존율, 1994-1998
최남경,윤경은,허대석,김윤이,이승미,박병주 한국역학회 2002 Epidemiology and Health Vol.24 No.2
Purpose : This study was conducted to estimate incidence, mortality and survival rate of lung cancer in the elderly people in Korea. Methods : Study population was Korean Elderly Phamacoepidemiologic Cohort (KEPEC). The lung cancer incidence cases were detected from three different sources, medical utilization database of the Korea Medical Insurance Corporation (KMIC), the database from the National Cancer Registry, and the database from the Regional Cancer Registry. The hospital survey to confirm the final diagnosis of the potential cases was conducted. A specialist on lung cancer reviewed the abstracted data to confirm the final diagnoses. The lung cancer death cases were detected from the mortality database at National Statistical Office. Incidence rate, survival rate and mortality rate of lung cancer and their 95% confidence intervals were estimated with SAS Window ver.8.1. Results : There were 213 confirmed lung cancer cases in KEPEC between Jan. 1994 and Dec. 1998. Age-standardized incidence rate of lung cancer to the Korean population was estimated to be 316.9 per 100,000 person-years in male and 65.2 per 100,000 person-years in female. Age-standardized mortality rate of lung cancer to the Korean population was estimated to be 342.3 per 100,000 person-years in male and 84.8 per 100,000 person-years in female. One years survival rate was 17% in male and 11% in female. Two year survival rate was 2% in male and 4% in female. Conclusion : Age-standardized incidence rate, age-standardized mortality rate and survival rate of lung cancer in the elderly Korean may be useful for further study and making health policy for managing lung cancer in the elderly.
Natural Menopause and Risk of Stroke in Elderly Women
Seong Hye Choi,Seung-Mi Lee,Yooni Kim,최남경,Yong Jin Cho,박병주 대한의학회 2005 Journal of Korean medical science Vol.20 No.6
Although early natural menopause has been postulated to increase stroke risk, stud-ies have not produced convincing results. We examined the associations between stroke risks and age at natural menopause or time since natural menopause. 5,731 naturally postmenopausal women more than 65 yr of age were followed from 1993 to 1998. Information on age at menopause and risk factors were obtained using mailed questionnaires. 186 cases of stroke occurred over a total 27,936 person-years. After adjusting for age, hypertension, and physical activity, age at menopause was not found to be significantly associated with stroke or cerebral infarction. How-ever, adjusted relative risks (aRRs) showed a significant increasing tendency of hemorrhagic stroke versus age at menopause (aRRs, 0.66, 0.48, 1.00 and 2.33 for the following age groups at menopause; 40-44, 45-49, 50-54 [reference group], and ≥55 yr). Time since menopause (11-20, 21-30, and ≥31 yr) was not found to be significantly associated with cerebral infarction, or hemorrhagic stroke. Late menopause (menopause age ≥55 yr) showed a tendency of a lower risk of cere-bral infarction (aRR, 0.79) and a higher risk of hemorrhagic stroke (aRR, 2.33). Fur-ther study is warranted to determine stroke risk in women during the decade follow-ing menopause.
Survey on antibody against bovine herpesvirus 1 (BoHV-1) in cattle in Korea
Choi, Eun-Jin,Song, Seungmin,Oem, Jae-Ku,Oh, Yooni,Kim, Eun-Ju,Song, Jae-Young The Korean Society of Veterinary Service 2014 韓國家畜衛生學會誌 Vol.37 No.2
This study was performed in Korea to get serological information for bovine herpesvirus 1 (BoHV-1), most commonly found in cattle. Antibodies against BoHV-1 were examined by targeting infectious bovine rhinotracheitis (IBR) in unvaccinated and vaccinated cattle, using viral neutralization (VN) test. In 2013, among 261 sera collected from IBR-unvaccinated herds, 7 sera (2.7%) were found seropositive and their VN titers were ranging from 1:4 to 1:32. Among 315 sera collected from IBR-vaccinated herds in large capacity farms, 303 sera (96.2%) were found to be seropositive for BoHV-1 and their VN titers were in the range of 1:4 to 1:2048. It was found that the IBR-vaccinated herds had higher levels of VN titer than IBR-unvaccinated herds. The results indicated that it may be due to heavy vaccination in vaccinated herds and no or a little infection in unvaccinated herds. At the end of the study it was concluded that although the seropositivity in IBR-unvaccinated herds was low, the monitoring of IBR should be continuously practiced to control and prevent the disease because of exportation of living cattle causing its nationwide outbreaks.