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- 저자 : InJae Kim (검색결과 230 건)
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JaeWoo Park,KeeHwan Park,KeunHo Joe,SookHee Choi,InJae Lee,JuHee Hwang,Min Kwon,ShengMin Wang,DaiJin Kim 대한신경정신의학회 2012 PSYCHIATRY INVESTIGATION Vol.9 No.3
Objective-The purpose of the study was to develop the Korean version of the Stage of Change Readiness and Treatment Eagerness Scale for Smoking Cessation (K-SOCRATES-S) based on the Korean version of the Stages of Readiness for Change and Eagerness for Treatment scale (K-SOCRATES). This paper also demonstrates its reliability and validity among patients with nicotine dependence in South Korea. Methods-At seven healthcare promotion centers in Gyeonggi-do, 333 male smokers aged 20 to 70 who visited smoking cessation clinic were recruited for this study and the K-SOCRATES-S was administered. After three months, the number of respondents who successfully stopped smoking was assessed by testing their urine cotinine level. Subsequently, exploratory factor analysis was performed to verify the reliability and validity of the K-SOCRATES-S. Also, a logistic regression analysis was performed to examine the variables that can predict the successful cessation of smoking on subscales of the K-SOCRATES-S. Results-Exploratory factor analysis of the K-SOCRATES-S showed that the scale consisted of three factors: Taking Steps, Recognition, and Ambivalence. The scales measuring Taking Steps and Recognition in this scale had a significantly positive correlation with the scores observed on Kim’s smoking cessation motivation scale. The scales measuring Taking Steps and Recognition had a significantly negative correlation with Ambivalence. Overall, the results indicate that the K-SOCRATES-K scale showed high validity. Conclusion-The K-SOCRATES-S developed in the present study is highly reliable and valid for predicting a patient’s likelihood of success in quitting smoking among patients who want to cease smoking.
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이향련 ( Lee Hyang Yeon1 ),오가실 ( Oh Ka Sil2 ),안양희 ( Ahn Yang Heui3 ),이숙자 ( Lee Sook Ja4 ),김인자 ( Kim Inja5 ) 경희대학교 동서간호학연구소 2010 동서간호학연구지 Vol.16 No.1
Purpose: The purpose of this study was to identify and evaluate outcome measurement scales of nursing education such as communication, professionalism, leadership, and critical thinking. Methods: A methodological study design was used to evaluate the reliability and validity of the scales. Survey was done to the students (n=407) enrolled in baccalaureate nursing schools. Using convenience sampling method, we tried to include all grades of students. Internal consistency, convergent validity and group comparison were used to evaluate the reliability and validity of the scales. Results: All scales were reliable and valid. Only convergent validity of the scale to measure critical thinking was relatively low. It suggested that critical thinking skill and disposition might be measured separately. Also it was inefficient to measure the nursing education outcomes with separate scales. Conclusions: It is recommended to develop a new integrative scale to measure nursing education outcomes. Also it is necessary to set the norm of nursing students to evaluate nursing education outcomes for the quality control of nursing education.
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Donghee Lee,Yelim Seo,Young-Won Kim,Seongtae Kim,Jeongyoon Choi,Sung-Hee Moon,Hyemi Bae,Hui-sok Kim,Hangyeol Kim,Jae-Hyun Kim,Tae-Young Kim,Eunho Kim,Suemin Yim,Inja Lim,Hyoweon Bang,Jung-Ha Kim,Jae-H 대한약리학회 2019 The Korean Journal of Physiology & Pharmacology Vol.23 No.5
Although atopic dermatitis (AD) is known to be a representative skin disorder, it also affects the systemic immune response. In a recent study, myoblasts were shown to be involved in the immune regulation, but the roles of muscle cells in AD are poorly understood. We aimed to identify the relationship between mitochondria and atopy by genome-wide analysis of skeletal muscles in mice. We induced AD-like symptoms using house dust mite (HDM) extract in NC/Nga mice. The transcriptional profiles of the untreated group and HDM-induced AD-like group were analyzed and compared using microarray, differentially expressed gene and functional pathway analyses, and protein interaction network construction. Our microarray analysis demonstrated that immune response-, calcium handling-, and mitochondrial metabolism-related genes were differentially expressed. In the Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology pathway analyses, immune response pathways involved in cytokine interaction, nuclear factor-kappa B, and T-cell receptor signaling, calcium handling pathways, and mitochondria metabolism pathways involved in the citrate cycle were significantly upregulated. In protein interaction network analysis, chemokine family-, muscle contraction process-, and immune response-related genes were identified as hub genes with many interactions. In addition, mitochondrial pathways involved in calcium signaling, cardiac muscle contraction, tricarboxylic acid cycle, oxidation-reduction process, and calcium-mediated signaling were significantly stimulated in KEGG and Gene Ontology analyses. Our results provide a comprehensive understanding of the genome-wide transcriptional changes of HDM-induced AD-like symptoms and the indicated genes that could be used as AD clinical biomarkers.
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Kim, Kwang S,Lee, Hong J,An, Jin,Kim, Yun B,Ra, Jung Chan,Lim, Inja,Kim, Seung U Pergamon Press ; Elsevier Science Ltd ; Elsevier S 2014 Cell transplantation Vol.23 No.12
<P>Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that selectively affects motor neurons in the cortex, brain stem, and spinal cord. The precise pathogenic mechanism remains unknown, and there is currently no effective therapy. We evaluated the therapeutic effects of human adipose tissue-derived stem cells (ASCs) in an animal model of ALS. Human abdominal subcutaneous fat tissues were obtained by simple liposuction from donors, and ASCs were isolated from the fat stromal vascular fraction. ASCs were found to differentiate into adipocytes, chondrocytes, osteocytes, and neurons. SOD1G93A ALS mice were divided into three groups: sham, intravenous (IV), and intracerebroventricular (ICV) groups. Human ASCs were transplanted in the ALS mice at 70 postnatal days before the appearance of clinical symptoms. Behavior of transplanted animals was assessed by rotarod test, paw grip endurance (PaGE), and reflex index. Mice in every group were sacrificed after 4 weeks posttransplantation. Transplanted ASCs were identified in the lumbar spinal cords with an antihuman mitochondria antibody and cell type-specific markers for neurons or astrocytes. Delayed onset of clinical symptoms (26 days) and extended survival of animals (24 days) were observed in ALS mice transplanted with ASCs via ICV route. ASCs were found to secrete high levels of neurotrophic factors such as NGF, BDNF, IGF-1, and VEGF. Reduction of apoptotic cell death by these factors was confirmed in cultured CNS cells and in the ALS spinal cord. These results indicate that transplantation of ASCs in ALS mice provides neuroprotective effects by production of cytokines/growth factors, delays disease progression, and prolongs the life span of ALS mice.</P>
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OPTIMIZATION OF THE RAYLEIGH FADING CHANNEL MODEL IN MOBILE ENVIRONMENT
Injae Won,Changhee Kim,Youngju Kim,Keehyun Lee 한국멀티미디어학회 2006 한국멀티미디어학회 국제학술대회 Vol.2006 No.-
Clarke's fading channel model is very simple simulator based on the SOS (Sum-Of-Sinusoids) and has been widely used. However, it has some shortcomings. Its time correlation properties based on the simulated waveform do not correspond to the statistical ones. In this paper, the difference between statistical and time properties of Clarke's fading channel model is examined and new simulator is proposed.
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Kim, Yoonkyung,Jung, Hye‐,youn,Choe, Yun Hui,Lee, Chaewoon,Ko, Sung‐,Kyun,Koun, Soonil,Choi, Yohan,Chung, Bong Hyun,Park, Byoung Chul,Huh, Tae‐,Lin,Shin, Injae,Kim, Eunkyoung WILEY‐VCH Verlag 2012 Angewandte Chemie Vol.124 No.12
<P><B>Mit photochromem Diarylethen vernetzte Dendrimere</B> (blau im Bild) wurden mit dem Fluoreszenzfarbstoff Cy3 (rot) zur reversiblen Fluoreszenzphotoschaltung markiert. Bestrahlt man die erhaltenen Nanocluster mit UV‐Licht, wird die Cy3‐Fluoreszenz durch das Diarylethen in seiner ring‐geschlossenen Form gelöscht, während Bestrahlung mit sichtbarem Licht die Nanocluster fluoreszieren lässt. In lebenden Zebrafischen konnten hochkontrastige Fluoreszenzbilder aufgenommen werden.</P>
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