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      • KCI등재

        대중교통 환승주차장의 CPTED 체크리스트에 의한 환경디자인 연구

        김대용(Kim, Dae Yong),김태용(Kim, Tae Yong),정승호(Chung, Seung Ho),박현호(Park, Hyeon Ho) 한국전시산업융합연구원 2012 한국과학예술융합학회 Vol.10 No.-

        본 연구는 늘어나는 대중교통인접 환승주차장의 범죄위험성으로부터 이용자들의 안전을 위하여 ‘환경설계를 통한 범죄예방(Crime Prevention Through Environment Design: CPTED, 이하: CPTED)"개념을 적용하여, 환경디자인 개선사항을 도출하는 연구이다. 연구의 방법과 범위로는 CPTED이론, 문헌분석, 관련법 및 법규, 관련 전문가그룹을 통하여 1차 정량·정성체크리스트를 설계하여 현장답사 하였으며, 이를 보안하는 2차 정성체크리스트를 설계, 현장답사 하였으며, 현장답사는 대중교통환승 주차장의 유형과 환승형태, 주차장규모, 운영주체등을 고려하여 수도권의 5개 환승주차장을 선정하였다. 설계된 체크리스트를 바탕으로 현장답사 결과 범죄위험성으로부터 환경디자인 개선사항은 5곳 중 1곳을 제외하고 4곳 모두 개선이 필요한 것으로 분석되었다. 분석은 주차지역, 유지관리, 전자보안, 안내표지, 조경, 조명으로 구분하였으며 조사대상지 대부분 범죄위험성으로부터 전자보안에만 의지하는 행태를 가졌으며, 그 또한 요금 징수 등을 주 목적으로 하고 있다. This study applies the concept of Crime Prevention Through Environmental Design (CPTED) and suggests ways to make improvements in environmental design to provide secure facilities for those who use park-and-ride structures which are increasing on a regular basis. First, the authors made a checklist for field examination after consulting related literature and related laws and holding discussion sessions with the experts of the field. After the field investigation with the quantitative and qualitative checklist, another qualitative checklist was developed to supplement the first one. With the second checklist, the authors visited five different park-and-ride structures around the city of Seoul that were diverse in layout, scale, and management system. The result showed that four out of the five sites assessed needed improvements. The analysis was divided into the following areas: location of the structure, maintenance, electronic security, signs, landscaping, and lighting. A popular method of crime prevention at the parking structures was electronic security which was in fact operated mainly to encourage the drivers to pay their parking fees.

      • KCI등재

        국립공원 내 파충류 자원의 효율적인 관리를 위한 PIT(passive integrated transponder) tag과 무선추적방법(radio telemetry)의 적용

        이정현 ( Jung Hyun Lee ),이헌주 ( Heon Joo Lee ),라남용 ( Nam Yong Ra ),김자경 ( Ja Kyeong Kim ),엄준호 ( Jun Ho Eom ),박대식 ( Dae Sik Park ) 한국환경생물학회 2009 환경생물 : 환경생물학회지 Vol.27 No.2

        본 연구는 PIT tag (passive integrated transponder)과 무선추적법(radio telemetry)을 오대산국립공원과 월악산국립공원에 서식하고 있는 파충류에 적용한 후, 이를 평가하여 효과적으로 국립공원 내 파충류 자원관리 방안을 모색하기 위하여 수행되었다. PIT tag은 현재까지 알려진 파충류 개체표시법 중에서 가장 효과적인 방법으로 2006년 3월부터 2008년 10월까지 오대산국립공원과 월악산국립공원의 조사지역에 출현한 모든 137마리의 뱀류를 대상으로 적용하였다. 무선추적 연구는 월악산국립공원에서 서식하고 있는 황구렁이(Elaphe schrenckii anomala) 2마리를 대상으로 2007년 9월부터 2008년 11월까지 실시하였다. 연구결과, 두 곳의 국립공원 지역에서 연구기간 동안 17마리가 재 포획되어 평균 12.40%의 재포획률을 보였으며, 재 포획된 개체들의 자료를 통하여 누룩뱀(Elaphe dione)과 쇠살모사(Gloydius ussuriensis) 성체의 SVL 증가를 성공적으로 확인하였다. 무선추적을 통하여 확인된 황구렁이 수컷의 행동권 면적은 MCP=389,600 m2, Kernel 95%=471,800 m2, 암컷은 MCP=162,500 m2, Kernel 95%=208,700 m2인 것으로 확인되었다. 국립공원 내에서 보호와 관리가 필요한 종 혹은 멸종위기대상 종인 파충류를 대상으로 PIT tag과 무선추적을 적용한다면 공원 내 파충류의 효율적인 관리 및 보존방안을 마련하는 데 중요한 기초자료를 제공할 수 있을 것으로 생각된다. To suggest effective ways of the management of reptiles in Korea national parks, we applied PIT (passive integrated transponder) tag and radio telemetry research methods in the monitoring of reptiles in Odaesan and Woraksan national parks. We implanted PIT tags into 137 snakes (six species) captured in both the national parks between March 2006 and October 2008 and also radio-tracked two Korean rat snakes (Elaphe schrenckii anomala) from September 2007 to November 2008 in the Woraksan national park. Of total 137 snakes which we had inserted the PIT tag, 17 snakes (12.40%) were recaptured. Based on the PIT tag data of the recapture, we successfully obtained the annual growth rate of Korean cat snakes (Elaphe dione) and Red-tongue pit-viper (Gloydius ussuriensis). Home range of the Korean rat snakes based on the data of radio-tracking was estimated as 389,600 m2 (MCP: Minimum convex polygon) and 471,800 m2 (Kernel 95%) for males and 162,500m2 and 208,700m2 for females. These results suggest that if we apply PIT tag and radio telemetry research methods to manage reptiles in Korea national parks, it could greatly increase our understanding about their basic ecology and as the result, it could allow us to develop better management and conservation ways of reptiles in Korea national parks.

      • SCIESCOPUSKCI등재
      • SCISCIESCOPUS

        Morin exerts cytoprotective effects against oxidative stress in C2C12 myoblasts via the upregulation of Nrf2-dependent HO-1 expression and the activation of the ERK pathway

        Lee, Moon Hee,Han, Min Ho,Lee, Dae-Sung,Park, Cheol,Hong, Su-Hyun,Kim, Gi-Young,Hong, Sang Hoon,Song, Kyoung Seob,Choi, Il-Whan,Cha, Hee-Jae,Choi, Yung Hyun UNKNOWN 2017 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Vol.39 No.2

        <P>In the present study, we investigated the cytoprotective efficacy of morin, a natural flavonoid, against oxidative stress and elucidated the underlying mechanisms in C2C12 myoblasts. Our results indicated that morin treatment prior to hydrogen peroxide (H2O2) exposure significantly increased cell viability and prevented the generation of reactive oxygen species. H2O2-induced comet-like DNA formation and gamma H2AX phosphorylation were also markedly suppressed by morin with a parallel inhibition of apoptosis in C2C12 myoblasts, suggesting that morin prevented H2O2-induced cellular DNA damage. Furthermore, morin markedly enhanced the expression of heme oxygenase-1 (HO-1) associated with the induction and phosphorylation of nuclear factor-erythroid 2-related factor 2 (Nrf2) and the inhibition of Kelch-like ECH-associated protein 1 (Keapl) expression. Notably, these events were eliminated by transient transfection with Nrf2-specific small interfering RNA. Additional experiments demonstrated that the activation of the Nrf2/HO-1 pathway by morin was mediated by the extracellular signal-regulated kinase (ERK) signaling cascade. This phenomenon was confirmed with suppressed Nrf2 phosphorylation and consequently diminished HO-1 expression in cells treated with a pharmacological inhibitor of ERK. Collectively, these results demonstrated that morin augments the cellular antioxidant defense capacity through the activation of Nrf2/HO-1 signaling, which involves the activation of the ERK pathway, thereby protecting C2C12 myoblasts from H2O2,-induced oxidative cytotoxicity.</P>

      • Vascular Protective Role of Samul-Tang in HUVECs: Involvement of Nrf2/HO-1 and NO

        Choi, Eun Sik,Lee, Yun Jung,Seo, Chang Seob,Yoon, Jung Joo,Han, Byung Hyuk,Park, Min Cheol,Kang, Dae Gill,Lee, Ho Sub Hindawi Publishing Corporation 2016 Evidence-based Complementary and Alternative Medic Vol.2016 No.-

        <P>Samul-Tang (Si-Wu-Tang, SMT), composed of four medicinal herbs, is a well-known herbal formula treating hematological disorder or gynecologic disease. However, vascular protective effects of SMT and its molecular mechanisms on the vascular endothelium, known as the central spot of vascular inflammatory process, are not reported. The aim of this study was to investigate vascular protective effects of SMT water extract in human umbilical vein endothelial cells (HUVECs). Water extract of SMT was prepared and identified by HPLC-PDA analysis. Expression of cell adhesion molecules (CAMs) and heme oxygenase-1 (HO-1) and translocation of nuclear factor-kappa B (NF-<I>κ</I>B) and nuclear factor-erythroid 2-related factor 2 (Nrf2) were determined by western blot. Nuclear localization of NF-<I>κ</I>B and Nrf2 was visualized by immunofluorescence and DNA binding activity of NF-<I>κ</I>B was measured. ROS production, HL-60 monocyte adhesion, and intracellular nitric oxide (NO) were also measured using a fluorescent indicator. SMT suppressed NF-<I>κ</I>B translocation and activation as well as expression of CAMs, monocyte adhesion, and ROS production induced by TNF-<I>α</I> in HUVECs. SMT treated HUVECs showed upregulation of HO-1 and NO which are responsible for vascular protective action. Our study suggests that SMT, a traditionally used herbal formula, protects the vascular endothelium from inflammation and might be used as a promising vascular protective drug.</P>

      • SCOPUSSCIEKCI등재

        두개골조기봉합증환자에서 3차원단층촬영영상의 이용

        박세혁,윤대영,이규호,오세문 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.7

        Technical advances in computer image analysis have made possible three-dimensional(3D) surface reformations of anatomic structures from contiguous axial CT slices We have recently utilized this 3D CT reconstruction with spiral CT scanner in S consecutive patients with primary or secondary craniosynostosis to assess the pres-ence and extent of synostosis. associated calvarial deformity and to facilitate surgical planning of ths craniectomy sits High resolution 3- mm contiguous CT sections were obtained and 3D shaded-surface reconstruction image gen-erated after reformation at f- mm interval In each case 9D CT demonstrated the exact extent of synostosis. and in 3 cases it was confirmed by surgical inspection 3D CT lmages facilitated surgical planning by precisely localizing the proper sits for craniectomy Three-dimensional CT with shaded-surface display may be a us㉣ful adjunct to im-aging and surgical planning in the patients with craniosynostosis. as well as a useful follow-up imaging study during observation or after surgery

      • SCOPUSKCI등재
      • 교차로계획에서 현대식 회전교차로(Modern Roundabout)의 도입 타당성

        박병호,송대섭 충북대학교 건설기술연구소 2003 建設技術論文集 Vol.22 No.2

        This study deals with the rationalities of modern roundabouts in the intersection planning. The goals are three-folds: (1) to compare modern roundabouts with the traditional traffic circles, and (2) to describe the types of modern roundabouts, and (3) to analyze the effectiveness of introducing the modern roundabouts to the intersection planning. The main results are as follows. Frist, the modern roundabouts have such the merits as improved safety, shorter delay, increased capacity and aesthetics compared to the traffic circles. Secondly, the modern roundabouts are described as six types of roundabouts according to the entering speed, number of lane, capacities and others. Finally, the literature survey shows that the roundabouts have such the general effects as the improved safety, decreased delay, urban aesthetics and other.

      • SCIESCOPUSKCI등재
      • 선천성상부요로기형에서 발생한 요석에 대한 체외충격파쇄석술

        박희수,박경민,정용호,김철성,장대수 조선대학교 부설 의학연구소 1999 The Medical Journal of Chosun University Vol.24 No.1

        Purpose: We sought to determine the efficacy of extracorporeal shock wave lithotripsy(ESWL) in the treatment of urolithiasis with congenital upper urinary tract anomalies. Materials and Methods: Using the Northgate SD-3 lithotriptor, 43 patients with calculi with upper urinary tract anomalies were treated with extracorporeal shock wave lithotripsy(ESWL) at Chosun University Hospital from 1996 to 1998. The upper urinary tract anomalies were duplicated ureter in 12 cases, bifid pelvis in 10, malrotated kidney in 4, ureterocele in 3, UPJ obstruction in 3, caliceal diverticulum in 3, horseshoe kidney in 3, pelvic kidney in 2, medullary sponge kidney(MSK) in 2 and polycystic kidney in 1. The age range of the patients was from 22 to 70 years of age(mean of 49.6 years). There were 23 men and 20 women. The mean size of the stone was 10.1x8.6±4.9x4.3mm, General or regional anesthesia was not required. Results: The average frequency was 2.3 sessions and the average number of shock wave was 2258±1404 shock. The 3-month stone free rate was 90.7%, Complications of stone removal were petechia in 43 cases, gross hematuria in 36, severe flank pain in 9 and urinary infection in 2. All complications were treated successfully with conservative management. Conclusion: We conclude that ESWL monotherapy is a safe and successful modality as a noninvasive management of urolithiasis in patients with upper urinary tract anomalies.

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