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      • Correction: Direct characterization of graphene doping state by <i>in situ</i> photoemission spectroscopy with Ar gas cluster ion beam sputtering

        Yun, Dong-Jin,Kim, Seyun,Jung, Changhoon,Lee, Chang-Seok,Sohn, Hiesang,Won, Jung Yeon,Kim, Yong Su,Chung, JaeGwan,Heo, Sung,Kim, Seong Heon,Seol, Minsu,Shin, Weon Ho The Royal Society of Chemistry 2018 Physical chemistry chemical physics Vol.20 No.4

        <P>Correction for ‘Direct characterization of graphene doping state by <I>in situ</I> photoemission spectroscopy with Ar gas cluster ion beam sputtering’ by Dong-Jin Yun <I>et al.</I>, <I>Phys. Chem. Chem. Phys.</I>, 2018, 20, 615-622.</P>

      • 6-(3,4-디클로로페닐)아미노-7-클로로-5,8-퀴놀린디온의 항진균작용 및 안전성 평가

        윤여표,김동현,이병무,허문영,정해문,강혜영,최정아,김도희,유충규 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

        6-(3.4-Dichlorophenyl)amino-7-chloro-5.8-quinolinedione (RCK50) was tested for antifungal activities in mice systemically infected with Candida albicans. The therapeutic potential of RCK50 was also assessed in comparison with ketoconazole. RCK50 had ED_50 0.22±0.01 ㎎/㎏. Ketoconazole as a positive control had ED_50 6.00±1.70 ㎎/㎏. Intraperitoneally administered RCK50 at the ED_50 for 7 days and 14 days reduced Candida albicans colony count in the kidneys and liver. And administered RCK50 at the ED_50 for 14 days improved survival rates. The genotoxicities of RCK50 had been evaluated. RCK50 was negative in Ames test with Salmonella typhimurium and chromosomal aberration test in CHL cells. RCK50 did not show any clastogenic effect in mouse peripheral blood and was negative in mouse micronucleus assay. These results indicate that RCK50 has no genotoxic potential under these experimental conditions. Acute oral toxicity studies of RCK50 were carried out in ICR mice of both sexes. RCK50 did not show acute oral toxicities and LD_50 values were over 2.850 ㎎/㎏ in ICR mice.

      • 企業의 海外進出에 대한 國際租稅對策에 관한 硏究

        정동윤 培材大學校 1997 培材論叢 Vol.2 No.-

        The purpose of this study is to suggest the adoption of some effective policies to taking some proper measure of strategic management for International Tax Planning of Korean overseas business and investments under the influences of Globaligation in the international enviornments, WTO, OECD etc. It is quite necessary to analyze and review the specified arrangements on the Tax incentives; and the Tax treaty and Tax convention under present systems. However, more effective counter measures in Tax Planning for overseas business and foreign direct investments are required with respect to the convention for avoidance of double Taxations and the prevention of fisical evasion from the Tax on Incomes and Capitals. and also, more active establishment in proper amendments on the present Tax Incentives systems requested to be encouraged practically for Korean overseas business operations. Espescially, enforcemental measurement of our Government should be utilized in coordination international Tax affairs by means of Transfer Pricing system, Thin Capitalization Rules, Anti-Tax Haven Rule, Mutual Agreement Procedure (MAP) etc, on International Tax cooperations for our overseas business. For above mentioned successful Arrangement of Tax incentives, Tax privileges on overseas business and Investments in both Law and Administrative aspects are carefully executed, and followings are pionted out as renedies on counter plannings. 1) Reserve for Loss of the Overseas Direct Investments should be accounted on the basic of the variable case by case. 2) The Deducation from income Tax amounts paid in foreign countries should be carried forward to the prior installment, and the period in respect to calculatating loss amount should be postponed. 3) More proper measurement on the deduction for Indirect Tax Credit from the overseas business should be secured. 4) The Conventions for the Elemination of Double Taxations with respect to the Tax on Incomes and on Capitals should be magnificated in negociations on the bilateral basis. 5) Enforcemental arrangement on the Tax Avoidance and Anti-Treaty Shopping of Multinational Enterprises should be strongly regulated.

      • 콘택트렌즈 보존 용기 유래 Acanthamoeba lugdunensis KA/L5주의 내공생세균

        정동일,공현희,김태호,황미열,유학선,윤호철,설성용 경북대학교 의학연구소 1999 경북대학교병원의학연구소논문집 Vol.3 No.1

        콘택트렌즈 보존 용기 유래 가시아메바 KA/L5주의 세포질 내에 존재하는 bacterial endosymbiont(내공생세균)를 투과전자현미경으로 관찰하여 확인하였다. 숙주인 가시아메바 KA/L5주는 형태학적으로 제2군에 속하였고, rDNA PCR-RFLP 결과 A. lugdunensis로 동정되었다. 미토콘드리아 DNA RFLP와 동위효소 분석상 이 충주는 국내 콘택트렌즈 보존용기에서 가장흔히 분리되는 type인 KA/Ll주, 국내 임상 분리주 중 하나인 KA/E2주, 내공생세균을 가지는 것으로 보고된 병원 냉각수 유래 KA/W4주 및 L3a주와 동일하거나 매우 유사한 성적을 보였다. 내공생세균은 약 1.38× 0.507㎛의 크기였고, 아메바 세포질 내에 불규칙하게 분포하고 있었으며. 그 표면에 아메바의 ribosome이 부착되어 있었다. 내공생세균을 둘러싼 lacunae나 막과 같은 구조는 관찰되지 않았다. Legionella 특이 primer를 이용한 효소중합반응(PCR)에서 내공생세균의 염색체 DNA는 증폭되지 않았다. A. lugdunensis의 우리말 이름을 담수가시아메바로 제안한다. Transmission electron microscopy of an Acanthamieba isolate (KA/L5) from a contact lens case revealed bacterial endosymbionts within cytoplasm of the amoebae, The Acanthamoeba isolate belonged to the morphological group II. Based on the polymerase chain reaction (PCR) - restriction fragment length Polymorphism (RFLP) of 18S ribosomal RNA coding DNA (rDNA), the Isolate was identified as A. lugdunensis. Strain typing by isoenzyme analysis using isoelectric focusing (IEF) and mitochondrial (Mt) DNA RFLP revealed that the isolate was closely related with KA/Ll , the most predominant type of isolates from contact lens storage cases, KA/E2, a clinical isolate, KA/W4, preciously reported to host endosymbionts, and L3a strains of A. lugdunensis. The endosymbionts were similar to those of KA/W4 In aspects that they were randomly distributed in both trophozoites and cysts, and were rod-shaped bacteria measuring approximately 1.38x 0.50㎛. But the number of endosymbionts per amoeba was significantly lower than that of KA/W4. They were neither limited by phagosomal membranes nor included In lacunae- like structure.

      • KCI등재

        고등학교 지구과학 실험·실습 요목 비교 분석

        정원우,이윤종,기우항,김영호,양승영,강용희,안병호,임성규,윤일희,김중욱,윤성효,강동진 경북대학교 과학교육연구소 1997 科學敎育硏究誌 Vol.21 No.-

        The purpose of this study is to investigate the status of the experimental and practical education in high school earth. The present status and reasonable management of the experimental and practical education in high school earth science have been grasped from the questionaires. To do this, eighty eight earth science teachers in Korea are administered questionaires. The frequency of the experimental and practical items in the seven kind of earth science text books were investigated. The problems and the reasonable management for experimental and practical education were proposed in this paper.

      • KCI등재

        한국판 아동용 예일-브라운 강박 척도:신뢰도와 타당도 연구

        정선주,이정섭,강윤형,조성진,서동혁,홍강의 대한소아청소년정신의학회 2000 소아청소년정신의학 Vol.11 No.1

        목적 : 본 연구는 소아, 청소년의 강박 증상을 평가하기 위한 도구인 아동용 예일-브라운 강박척도(Childen's Yale-Brown Obsessive Compulsive Scale : Y-BOCS)의 한국판을 제작하여 그 신뢰도와 타당도를 검증하고자 시행되었다. 방법 : 강박장애로 진단된 42명의 아동과 청소년들을 대상으로 CY-BOCS를 시행하였다. 평가자간 신뢰도를 측정하기 위하여 20명의 환자를 2명의 평가자가 동시에 면담하였다. 수렴타당도와 변별타당도의 검증을 위해 총괄적인 임상 인상척도-강박장애(Clinical Global Impression-Obsessive Com-pulsive Disorder : CGI-OCD). 아동용 Leyton 강박 척도(Lryton Obsessional Inventory-Child Version : LOI-CV), 소아우울척도(Child Depression Inventory : CDI), 소아 상태-특성 불안척도(State-Trait Anxiety Inventory for Children : STAI-C)를 시행한다. 결과 : Cronbach's α값으로 평가한 내적 일치도는 0.86으로 높게 나타났다. CY-BOCS 전체 점수 강박사고, 강박행동 소척도 점수에 대한 군내 내적일치도는 각각 0.94. 0.94. 0.84로 우수한 평가자간 일치도를 보였다. CY-BOCS 전체 점수와 CGI-OCD 점수간의 상관관계는 매우 높게 나타났고(r-0.88), LOI-CY 총점과도 통계적으로 유의한 상관관계(r=0.51)가 관찰되었다. CY-BOCS 전체 점수와 STA-I-C의 상태불안 점수간에는 상관관계가 나타나지 않았고(r=0.25), 특성불안 점수(r=0.43) 및 CDI 점수(r=0.49)와는 유의한 상관관계를 나타냈다. 결론 : 본 연구결과, 한국판 CY-BOCS의 높은 타당도 및 신뢰도가 입증되었으며, 향후 강박 증상의 객관적인 평가 및 정량화를 위해 유용하게 사용될 수 있을 것이다. Objective : This study was carried out to evaluate the reliability and validity of the Korean form of the Children's Yale-Brown Obsessive Compulsive Scale(CY-BOCS). Method : Forty-two children with obsessive-compulsive disorder(OCD)(31 boys and 11 girls, aged 7 to 18 years) were assessed with CY-BOCS. Interrater agreement was assessed by two raters in subsample(n=20). discriminant and convergent validity were assessed by comparing CY-BOCS scores to Clinical Global Impression-OCD(CGI-OCD), Leyton Obsessional Inven-tory-Child Version(LOI-CV), State-Trait Anxiety Inventory for Children(STAI-C), and Child Depression Inventory( CDI ). Results : Internal consistency was high, measuring 0.86 for the 10 items and total score. The intraclass correlations for the CY-BOCS total, obsession, and compulsion scores were 0.94, 0.94, 0.84, suggesting excellent interrater agreement for subscale and total scores. The CY-BOCS total score showed highest correlation with CGI-OCD(r=0.88), and significant correlation with LOI-CV(r=0.51), Trait Anxiety score(r=0.43), and CDI scores(r=0.49), but it was not correlated with State-Anxiety score(r=0.25). Conclusion : The results of this study indicate that the Korean form of CY-BOCS is a reliable and valid scale for rating obsessive-compulsive symptom severity. KEY WORDS : Development · Rating scale · Obsessive-compulsive disorder · Reliability Validity.

      • KCI등재

        상악 결손부 수복을 위한 측두피판의 이용

        정창주,진국범,이동근,윤성필,김귀희,김영조 大韓顎顔面成形再建外科學會 1994 Maxillofacial Plastic Reconstructive Surgery Vol.16 No.1

        The functional deformity following removal of the maxilla is considerable, especially following maxilla cancer excision. Rehabilitation of oral and maxillofacial region used to be very difficult with prosthesis or traditional flaps. Temporal muscle and fascia flaps have been described for immediate reconstruction following hemi-maxillectomy, but not total maxillectomy. The muscle and superficial fascia of the temporal area differ in their physical characteristics, vascular supply and clinical applications. Both can be employed independently or simultaneously as regional flaps in the reconstruction of a variety of complex craniofacial defects. Four case is presented in which 3 case maxilla cancer, one case non-union after maxilla fracture, and all case showed successful use of this flap. Only one patient developed partial necrosis of the flap ; significant necrosis did not occur in any other patient. This present paper reviews the anatomy, surgical technique and utilisation of temporal muscle and fascia flaps.

      • KCI등재

        Cervical Headgear와 Anterior bite plate를 이용한 Ⅱ급 부정교합의 치험례

        손동수,이상훈,장기택,박윤정 大韓小兒齒科學會 1995 大韓小兒齒科學會誌 Vol.22 No.2

        The headgear is an extraoral appliance which used to distal movement of the teeth, inhibition of maxillary growth and reinforcement of anchorage. In case of treatment of Class Ⅱ malocclusion, however, it is not sufficient to simply restrict the horizontal growth of maxilla but to need treatment on mandibular retrusion. Generally, the combination theraphy of activator and headgear is conventional, but other study about combination therapy with other intraoral removable appliance is done. In this case, theatments were done by the combination therapy of headgear and anterior bite plate. The results were followed: 1. Reduction of SNA, upper lip to esthetic plane and lower lip to esthetic plane were observed. 2. 1 to FH plane angle was corrected. 3. Severe overbite, large overjet, and deep curve of spee was corrected. 4. Class Ⅱ molar relation was changed by class Ⅰ.

      • 일차배양 간세포를 이용한 Nitric Oxide(NO)의 항산화 활성 및 약물대사 효소에 미치는 영향

        남성윤,정연봉,김동석,이종철 慶星大學校 1996 論文集 Vol.17 No.2

        The purpose of the present study was to determine the antioxidative activity and effects on drug metabolism of nitric oxide. In experiments, the incubation of isolated rat hepatocytes with lipopolysaccharide(LPS) resulted in the slight inhibition of lipid peroxidation but superoxide productivity not affected. Also LPS increased intracellular glutathione and glutathione S-transferase activity. In contrast, N??-monomethyl-L-Arginine (L-NMA), an inhibitor of both the constitutive and inducible nitrix oxide synthases, decreased in lactate dehydrogenase. And, LPS inhibited increasse of ethoxycoumarin O-deethylase activity by phenobarbital, but other monooxygenase activity not affect. Treatment of L-NMA to phenobarbital -pretrteated rat hepatocytes results in slight increase of cytochrome P-450 I Al specific enzyme ethoxyresorufin O-deethylase activity.

      • KCI등재

        생물막 공정에서 질소제거효율 향상을 위한 유기성담체의 효용성 검토

        최동욱,최영균,김대영,김윤중,정태학 대한상하수도학회 2003 상하수도학회지 Vol.17 No.3

        Availability of organic media for improving nitrogen removal efficiency in a biofilter process was studied. Although, aerobic and anoxic phase could be clearly divided during the operation of single-stage biofilter process and nitrification efficiency was about 80%, denitrification efficiency was very low due to depletion of organic substrate in anoxic phase. However, the deficiency could be improved by addition of organic media in anoxic phase from the simulated result. Nitrogen removal efficiency in a biofilter process packed with organic media in anoxic phase was predicted to be 29% higher than that packed with inorganic media. In addition, about 79% of nitrogen removal efficiency could be obtained from a column test using organic media innoculated by activated sludge. Improvement in nitrogen removal efficiency was responsible for organic leaching from the organic media and the leaching rate was 0.21㎎COD/g-org.media/day.

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