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高 Mn鋼의 冷間加工에 의한 物性的인 變化와 機械的性質에 관한 硏究
조성석,千炳善,李揆暢 충남대학교 공업교육연구소 1981 論文集 Vol.4 No.1
Austenite series high Mn-steels have a good wear-resistance but its preferred precipitation along the grain-boundary is the weakest point. Authors have studied on the prevention of preferred precipitation along the grain-boundary by the cold-working. Cold-working ranging from 10% to 30% was carried out in the liquid nitrogen atmosphere. Wear-resistance by cold-working was increased in 0.06-0.2㎎/113㎟ than the age-hardened materials. This can be explained by the effect of cold-working which induces the phase-transformation and cause to fine the grain-boundary.
건축공사시방서에서의 KS규격의 국제인증방안에 관한 연구
김경식,이재섭,김용수,이규진,조용훈,최완철,전재열,이현수,구재동,이기환 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1
The purpose of this research is make out construction specifications for International Construction. Using off-shore products incur cost increase and longer delivery term of construction. and inconvenient on International Construction. Expand the range of additional local products conforming to performance. Life Cycle Cost. maintainability. operability. user's acceptability, etc.. And this study is suggest the standard formats and the techniques for construction specification.
Cho, Seok Goo,Min, So-Youn,Park, Min Jung,Lee, Kyung Wha,Cho, Young-Gyu,Cho, Mi-La,Chang, Hong Seok,Park, Se-Ho,Lee, Jong Wook,Min, Woo Sung,Kim, Chun Choo,Kim, Ho-Youn Wiley Subscription Services, Inc., A Wiley Company 2006 Vol.54 No.6
<B>Objective</B><P>To investigate the immunoregulatory effects of allogeneic mixed chimerism induced by T cell–depleted, nonmyeloablative bone marrow transplantation (BMT) on chronic inflammatory arthritis and autoimmunity in mice deficient in interleukin-1 receptor antagonist (IL-1Ra).</P><B>Methods</B><P>IL-1Ra<SUP>−/−</SUP> mice (H-2K<SUP>d</SUP>) were treated with antibody to asialoganglioside G<SUB>M1</SUB> (anti–natural killer cell), total body irradiation (500 cGy), and T cell–depleted, nonmyeloablative BMT derived from C57BL/6 mice (H-2K<SUP>b</SUP>). Engraftment and chimerism were evaluated in peripheral blood, lymph nodes, and spleen by multicolor flow cytometry. The severity of arthritis was evaluated by clinical scoring and histopathologic assessment. Levels of IgG1 and IgG2a subtypes of anti–type II collagen (anti-CII) antibodies were measured in serum samples. After T cells were stimulated with CII, ovalbumin, and phytohemagglutinin, T cell proliferative responses and levels of cytokine production (interferon-γ [IFNγ], tumor necrosis factor α [TNFα], interleukin-10 [IL-10], and IL-17) were assayed in culture supernatants.</P><B>Results</B><P>All IL-1Ra<SUP>−/−</SUP> mice receiving BMT showed marked improvement in arthritis within 3 weeks, as well as successful induction of mixed chimerism. These mice showed higher levels of IgG1, and lower levels of IgG2a anti-CII antibodies and weaker T cell proliferative responses than did mice in the control groups (either no treatment or conditioning alone without bone marrow rescue). In mixed chimeras, the levels of IFNγ, TNFα, and IL-17 produced from CII-stimulated T cells were significantly suppressed and IL-10 production was significantly higher as compared with controls.</P><B>Conclusion</B><P>The introduction of allogeneic mixed chimerism showed a strong immunoregulatory potential to correct established chronic inflammatory arthritis and autoimmunity originating from a dysregulated proinflammatory cytokine network.</P>
Cho, Chang-Won,Ahn, Sungeun,Lim, Tae-Gyu,Hong, Hee-Do,Rhee, Young Kyoung,Yang, Deok-Chun,Jang, Mi Carfax 2017 MEDIATORS OF INFLAMMATION Vol.2017 No.-
<P>We recently reported the immune-enhancing effects of a high-molecular-weight fraction (HMF) of CW in macrophages and immunosuppressed mice, and this effect was attributed to a crude polysaccharide. As polysaccharides may also have anti-inflammatory functions, we investigated the anti-inflammatory effects and related molecular mechanisms of a crude polysaccharide (HMFO) obtained from HMF of CW in mice with dextran sulfate sodium- (DSS-) induced colitis and in lipopolysaccharide-induced RAW 264.7 macrophages. HMFO ameliorated the pathological characteristics of colitis and significantly reduced production of proinflammatory cytokines in the serum. Histological analysis indicated that HMFO improved the signs of histological damage such as abnormal crypts, crypt loss, and inflammatory cell infiltration induced by DSS. In addition, HMFO inhibited iNOS and COX-2 protein expression, as well as phosphorylated NF-<I>κ</I>B p65 levels in the colon tissue of mice with DSS-induced colitis. In macrophages, HMFO inhibited several cytokines and enzymes involved in inflammation such as prostaglandin E<SUB>2</SUB>, nitric oxide, tumor necrosis factor-<I>α</I>, interleukin-6, inducible nitric oxide synthase, and cyclooxygenase-2 by attenuating nuclear factor-<I>κ</I>B (NF-<I>κ</I>B) and mitogen-activated protein kinases. HMFO attenuated inflammation both in vitro and in vivo, primarily by inhibiting NF-<I>κ</I>B activation. Our findings indicate that HMFO is a promising remedy for treating inflammatory bowel diseases, such as colitis.</P>
Chun, Ji-Yeon,Kim, Byong-Soo,Lee, Jung-Gyu,Cho, Hyung-Yong,Min, Sang-Gi,Choi, Mi-Jung Korean Society for Food Science of Animal Resource 2014 한국축산식품학회지 Vol.34 No.5
Sodium chloride is an important ingredient added to most of foods which contributes to flavor enhancement and food preservation but excess intake of sodium chloride may also cause various diseases such as heart diseases, osteoporosis and so on. Therefore, this study was carried out to investigate the effect of monosodium glutamate (MSG) as a salty flavor enhancer on the quality and sensorial properties of the NaCl/MSG complex and actual food system. For characterizing the spray-dried NaCl/MSG complex, surface dimension, morphology, rheology, and saltiness intensity were estimated by increasing MSG (0-2.0%) levels at a fixed NaCl concentration (2.0%). MSG levels had no effect of the characteristics of the NaCl/MSG complex, although the addition of MSG increased the surface dimension of the NaCl/MSG complex significantly (p<0.05). Furthermore, the effect of MSG on enhancing the salty flavor was not observed in the solution of the NaCl/MSG complex. In the case of an actual food system, model meat products (pork patties) were prepared by replacing NaCl with MSG. MSG enhanced the salty flavor, thereby increasing overall acceptability of pork patties. Replacement of NaCl with MSG (<1.0%) did not result in negative sensorial properties of pork patties, although quality deterioration such as high cooking loss was found. Nevertheless, MSG had a potential application in meat product formulation as a salty flavor enhancer or a partial NaCl replacer when meat products were supplemented with binding agents.
Prospective assessment of risk of bacteremia following colorectal stent placement.
Chun, Yeon Joo,Yoon, Na Ri,Park, Jae Myung,Lim, Chul-Hyun,Cho, Yu Kyung,Lee, In Seok,Kim, Sang Woo,Choi, Myung-Gyu,Choi, Kyu Yong,Chung, In-Sik Plenum Pub. Corp.] 2012 Digestive diseases and sciences Vol.57 No.4
<P>Colorectal stent insertion is an invasive endoscopic procedure. However, there are no reports regarding the incidence of bacteremia with colorectal stent.</P>