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초기발생 말똥성게의 점액질에 미치는 Phenol독성에 대한 조직화학적 연구
고대재,최병태,조운복 부산대학교 환경문제연구소 1994 環境硏究報 Vol.12 No.-
Phenol이 초기발생 말똥성게의 점액질에 미치는 영향을 조직화학적으로 검색하였다. 대조군의 위란강내에는 다량의 중성점액질과 소량의 산성점액질을 함유하며 산성점액질의 성상으로 보아 nonsulfated mucin과 sulfated mucin을 미량 함유하였다. 난세포에는 중성점액질만 중등량 함유하며 발생 중 배의 일반세포에는 미량 내지 소량의 중성 및 산성점액질을 가지며 산성점액질의 성상으로 보아 미량의 nonsulfated mucin과 sulfated mucin을 함유하고 있었다. phenol실험군의 염색성 변화는 현저하지 않았으나 발생이 지체된 수정난의 위란강내점액질은 대조군보다 다소 많이 함유하고 있었으며 1 및 10ppm농도에서 수정막을 탈피하지 못한 포배 및 낭배의 위란강에는 수정막형성기와 2세포기와 유사한 점액질을 함유하고 있었다. The effect of phenol toxicity on the mucopolysaccharides in the early developmental stages of sea urchin(Hemicentrotus pulcherrimus) were studied by histochemical methods. Sea urchin were induced to develope from the fertilized egg to gastrula in sea water with various concentration of phenol. About the amounts and histochemical properties of mucopolysaccharides, perivitelline space were mixed with large amounts of neutral and small amounts of acid mucopolysaccharides. The egg cells contained moderate amounts of neutral mucopolysaccharides only. General cells of blastula and gastrula contained small to minimal amounts of neutral and acid mucopolysaccharides. About the properties of acid mucopolysaccharides, minimal amounts of nonsulfated and sulfated ones were present in the perivitelline space and general cells of blastula and gastrula. The effect of phenol toxicity on the mucopolysaccharides was not significant. However, in the phenol treated groups, retarded fertilization egg showed a little more mucopolysaccharides in the perivitelline space than the control group. In the 1 and 10ppm phenol treated groups, the retarded blastula and gastrula having fertilization membrane showed a similar distribution pattern of mucopolysaccharides existed in perivitelline space to that of the fertilization membrane and 2-cell stages.
최희원(Hee Won Choi) 전고운(Ko Un Chun) 김황민(Hwang Min Kim) 차병호(Byung Ho Cha) 대한소아신경학회 2004 대한소아신경학회지 Vol.12 No.1
저자들은 18개월 된 여아에서 주기성 빈호흡과 무호흡, 정신 발달 지체, 안구 운동 이상의 소견을 보여 실시한 뇌 자기공명 영상에서 소뇌 충부의 완전 결손을 보여 Joubert 증후군으로 진단된 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Joubert syndrome is a rare autosomal recessive condition characterized by dysgenesis of the cerebellar vermis, hypotonia, developmental delay, ataxia, abnomial eye movements, and a respiratory pattern of alternating tachypnea and apnea. Brain MRI shows the molar tooth sign resulting from dysplasia of the isthmic segment of the brain stem, superior cerebellar peduncles, and vermis. We experienced a case of Joubert syndrome, who was a 18 month-old female with episodic hyperpnea, developmental delay, abnormal eye movements and complete agenesis of the cerebellar vermis. We present this case with a brief review of literature.
고대석,최순석,정수진,박준한,이헌,손병철,엄상화,이채언,배기택,전진호 大韓産業醫學會 1997 대한직업환경의학회지 Vol.9 No.1
This study was conducted to estimate the causing factors of industrial accident, and to prepare the fittable control program for accident through the evaluation of views of the patients who suffered from accidents. From January 5 to February 6 1993, questionnaire survey was executed on 166 persons who were injured and covered by the insurance under industrial accident compensation law at four university hospitals in Pusan. The results were as follows : 1. Most of subjects worked in the manufacturing(56.6%) and constrution(29.5%), and in the small factory less than 49 workers(56.0%). They were thirties and fourties(63.8%), less than 3 years tenure(53.6%), habitual drinker(69.2%). And, 72.3% worked for above 9 hours per day, 53.6% worked as near clerks, 89.2% thought that work is rather suitable to his own personality. 2. Self-recognition for the causing factor of industrial accident was the other's malfunction(19.3%), carelessness(15.1%), lack of education for satefy(15.1%), and they thought the accident occured by mainly some defect of establishment and working environment (34.9%), unskillfulness(22.9%0, self-carelessness(22.3%). 3. The interests and recognition on safety was insufficient, 88.6% require job education, but 53% pointed out the necessity for strengthening of present status - rather incomplete with relying on self-education(40.9%), no previous participation in safety education(29.5%), etc. 4. For the kind of accident, fall-down(16.3%), crash(13.3%), falling(12.7%) was frequent, head(24.7%) and fracture(41.0%) was frequent for the part and type of injury, respectively. And, they had more injured by cooperative work(82.5%) than single work. As results, improvement of working environment and strengthening education program would be emphasized for the effective control of industrial accident. And, there should be prepared the specific prevention program for the small scale industries.
Ko, Young Un,Cho, Sung-rheb,Choi, Kyoung Soon,Park, Yensil,Kim, Sung Tae,Kim, Nam Hee,Kim, Soo Young,Chang, Suk Tai The Royal Society of Chemistry 2012 Journal of materials chemistry Vol.22 No.8
<P>We report a new class of rapid solution processes for fabricating highly uniform chemically derived graphene thin films with control over the thickness on the subnanometre scale. The film deposition directly on various substrates is driven by dragging a meniscus of microlitre graphene oxide (GO) suspension trapped between two plates. The fine tuning of the optoelectronic properties of the graphene thin films is achieved by simply varying the number of depositions, GO concentration, dragging speed, and angle between two plates. This coating technique is simple, inexpensive, and easy to scale for large-area graphene films used as transparent electrodes with a significant reduction of the material consumption.</P> <P>Graphic Abstract</P><P>A new class of rapid microlitre scale solution processes for fabricating highly uniform and large-area chemically derived graphene thin films has been developed. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2jm15299a'> </P>
( Un Suk Jung ),( Kyung Tai Kim ),( Jae Man Bae ),( Won Moo Lee ),( A Ra Koh ),( Jung Hwa Ko ),( Joong Sub Choi ) 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-
목적: The purpose of this study was to evaluate the feasibility and efficacy of laparoscopic para-aortic lymphadenectomy (LPAL) to the level of the left renal vein for patients with gynecologic malignancies. 방법: We conducted a retrospective chart review of 283 patients with gynecologic malignancies who had undergone LPAL by a single surgical team between November 2003 and July 2014. We evaluated demographic characteristics, surgical outcomes, and, lymphadenectomy-related complications. 결과: Two hundreds and seventy-seven patients underwent LPAL in part of staging, restaging, and debulking surgery. Six patients with isolated para-aortic lymph node recurrence underwent a repeat LPAL. The median age and body mass index of the patients were 54 years (range 28?81 years) and 26.0 kg/m² (range 20.3?37.2 kg/m²). The median numbers of harvested para-aortic lymph nodes were and 10 (range 1? 36). The median operating time was 40 minutes (range, 20?70 min). There were eight cases of intraoperative complications: five cases of major vessel injuries (three in inferior vena cava injuries, one in aorta, and one in common iliac vein) and three cases of ureteric injuries. There were four postoperative complications: two in lymphocysts and two cases of chylous ascites. There were two conversions to laparotomy: one case was to repair of left common iliac vein laceration and another to remove completely enlarged para-aortic lymph node. 결론: It is feasible and efficient to perform LPAL to the level of the left renal vein for women with gynecologic malignancies by well-trained gynecologic oncologic surgeons.
최인철,김성덕,고홍,김광우,김석곤,민성원,노시운,김계용,정영균 대한마취과학회 1988 Korean Journal of Anesthesiology Vol.21 No.6
We experienced one case of anesthesia for liver transplantation in a 14-year-old girl with Wilson's disease. The liver was donated from a patient with a brain tumor who was diagnosed as brain death. We monitored blood pressure, heart rate, cardiac output, pulmonary capillary wedge pressure, systemic vascular resistance, arterial pH, arterial PCO_2, serum potassium, ionized calcium, glucose, and blood coagulation states including platelet count, prothrombin time, activated partial thromboplastin time and coagulation factor assay, We used isoflurane and nitrous oxide as the main inhalation anesthetics. The operation was performed without serious problem. The patient became conscious three hours after the operation.