Antiangiogenic-Like Properties of Fermented Extracts of Ayurvedic Medicinal Plants

Che´rif Rabhi,Guillaume Arcile,Le´on Cariel,Christine Lenoir,Je´rome Bignon,Joanna Wdzieczak-Bakala,Jamal Ouazzani 한국식품영양과학회 2015 Journal of medicinal food Vol.18 No.9

The three ayurvedic medicinal plants, Withania somnifera, Emblica officinalis, and Bacopa monnieri, were extracted by high-pressure static extraction using the Zippertex® technology. The extracts were mixed to reach quantifiable amounts of active compounds identified by high-pressure liquid chromatography-mass spectrometry (HPLC-MS) analysis. The mixture of extracts was incubated with resting cells of the fungus Beauveria bassiana ATCC 7159. The fermentation promoted the fluidization of the starting dense mixture, while HPLC monitoring evidenced the disappearance of glucogallin from E. officinalis extract and the concomitant increase in gallic acid content. Topical exposure of the chick embryo chorioallantoic membrane (CAM) to the nonfermented extract led to the extensive necrosis and destruction of the treated membrane. However, the fermented extract was shown to be free of any toxicity. Furthermore, compared with the untreated CAM, the fermented sample reduced CAM vascularization, suggesting its antiangiogenic potency. The innocuity of the fermented extract was demonstrated using the in vivo LD50 test, the morphological examination of internal organs of treated rats, as well as the evaluation of blood biomarkers of liver damage (aspartate aminotransferase and alanine aminotransferase). The fermented extract was developed as a nutraceutical antiangiogenic treatment of age-related macular degeneration and commercialized in an oral form named Ethnodyne-Visio™.

제주 우수 수영 선수들의 년중 훈련효과 분석 및 처방

김철원,임상용,김승곤,오만원,김성찬,이창준,남사웅,이세형,류재청 濟州大學敎 體育科學硏究所 1996 체육과학연구 Vol.2 No.-

The study was undertaken to analysis, evaluate, and prescribe the annual effect of training of periodically anaerobic and erobic motor ability for Che-Ju representive team of elementary, middle and high school athletes, first the performance can be obtained when it was prescribed proper training after analysis of physical fitness by each events, second individually fitness scientific analysis. prescription. proper management of athlete will be necessary to apply.

제주 우수 육상경기 선수들의 년중 훈련효과 분석 및 처방

김철원,임상용,김승곤,오만원,김성찬,이창준,남사웅,이세형,류재청 濟州大學敎 體育科學硏究所 1996 체육과학연구 Vol.2 No.-

The study was undertaken to analysis, evaluate, and prescribe t h e annual effect of training of periodically anaerobic and aerobic motor ability for Che-Ju representive team of elementary, middle and high school athletes. first. the performance can be obtained when it was prescribed proper training after analysis of physical fitness by each events. second, individually fitness. scientific analysis. prescription. proper management of athlete will be necessary to apply. In addition to physiology aspect, it is essential to consider sport biomechanics. sport psychology when we prescribe specific events and necessary approach in demension coach-athlete-researcher for individual.

의료소비자의 관계혜태 지각이 관계의 질 및 행동의도에 미치는 영향

허철선(Che이-Seon Heo),유광우(Kwang-Woo Yoo) 한국무역연구원 2014 무역연구 Vol.10 No.1

Medical institutions are important to develop and maintain enduring relationship with medical service conswners. So, this research aims to find out the effect of medical service conswners perception of relational benefits on relationship quality and behavioral intention. On the basis of the literature review, the research model is established. This research has been done through the survey utilizing medical service consumers in Gangwondo, and the effective 368 questionnaires are tested for the research model. The main findings are as follows. First, among 5 key dimensions of relational benefits, psychological, customization, economic, and information benefits except social benefits have significant effects on relationship satisfaction. Also, medical institutions type and medical service consumers type as moderating variables are included concurrently, and the significant differences are found in other 4 benefits except relationship between social benefits and relationship satisfaction. Second, relationship satisfaction relates positively to relationship commitment and behavioral intention. But the normative commitment, one of 3 key dimensions of relationship commitment, has no significant effects on recommendation to others. Third, the revisit intention has significant effect on recommendation to others. Finally, the findings reveal that the overall goodness fit index of the model is comparatively good and model set in this research is significant. At the end of the research, managerial implications, limitations and future research directions are suggested.

의료 화상을 위한 전처리 필터들의 특성에 관한 연구

강명아,최종주,정종필,정채영,정남채 조선대학교 기초과학연구소 1997 自然科學硏究 Vol.20 No.1

There has been no fixed rule of pre-processing course required to do image processing that it was barely possible to find the proper pre-processing course, only to process with experience till now. In this paper, lots of application method of pre-processing algorithm, only available by the non-typified and experiential method, shall quantify and the algorithm method of algorithm according to the rule shall calculate the frequency of the value of each pixel gray level and the histogrm of the image. And then average it to all pixel number and finally set a high-ranking or optional % standardized by the average value in teh standard value. The result of a experiment showed the Median filter is superior to the Mean filter in all image of the smoothing filter. The sobel filter extracted feature. The laplacian filter presented sectional feature which not showed in original image.

商業空間FACADE의 視知覺的 構成要素에 關한硏究 : 압구정동의 Fashion Shop을 중심으로 Focusing on the Fashion Shop of Apkujong Dong

林采震,鄭漢浩 홍익대학교 산업기술연구소 1999 産業技術 Vol.9 No.-

박물관 건설경영에 관한 연구

林采震,文鍾承 홍익대학교환경개발연구원 2001 환경개발연구논문집 Vol.6 No.-

An instance of domestic exhibition facility building case, the shortage of managing personal constructive resulted serious issue on expenses, times, quality, and safty with no satisfaction on its process and result. According to subject's speciality the CM's application methods are varied and because of its speciality, overall process of building an exhibition facility operating by its owner. This study intends to exam a application possibility of CM on exhibition facility construction to make smooth communication among varied area that following to exhibition facility construction.

근로 장애인의 직무만족도에 영향을 주는 심리사회적 변인에 관한 연구

이채식,김명식 한국장애인고용공단 고용개발원 2012 장애와 고용 Vol.22 No.1

This study investigated exploratorily the effect of disability acceptance, job stress, motivation for work, and job attitude influencing the job satisfaction of the working people with disabilities. And it tried to search and suggest the interventions of policy and practice for enhacing their job satisfaction. It used and analyzed the data of 'The 3rd Survey of Employment of the Disabled(2011)" by Korea Employment Promotion Agency for the Disabled. Main results are as follows: The disability acceptance positively influenced the job satisfaction and 'work and interpersonal relation job stress' negatively the job satisfaction, and 'no option' negatively did. The more they perceive their work according with their job aptitudes, the more they perceive their job satisfactions. Therefore its main results will be seem to be used as basic data for suggesting the ways of policy and practice for the disabled. 본 연구는 근로 장애인의 직무만족에 영향을 미치는 요인을 장애수용, 직무 스트레스, 근무동기, 직무적성 등 심리사회적인 변인을 중심으로 구분하여 탐색적으로 검증하고, 본 연구결과를 토대로 근로 장애인의 직무만족도를 높일 수 있는 정책적ㆍ실천적 개입방안을 제시하는데 그 목적이 있다. 이러한 요인을 규명하기 위해 한국장애인고용촉진공단에서 실시한 ‘제3차 장애인고용패널조사(2011)’ 데이터를 활용하였다. 분석결과 장애수용이 직무만족에 긍정적 영향을 주는 것으로 나타났고, 직무스트레스에서는 ‘일과 대인관계’가 직무만족에 부정적 영향을 주는 것으로 나타났다. 또한 근무동기에서는 ‘대안이 없어서’가 직무만족에 부정적 영향을 주며, 직무적성이 직무만족에 주는 영향에서는 직무적성이 일치한다고 지각할수록 직무만족에 긍정적 영향을 주는 것으로 나타났다. 따라서 본 연구 결과는 향후 근로 장애인의 직무만족을 높일 수 있는 정책적ㆍ실천적 개입 방향을 설정하는 데 있어서 중요한 기초자료로 활용될 수 있을 것이다.

부하수준에 따른 보행양상과 일치도에 관한 연구

류재청,김철원 제주대학교 1994 논문집 Vol.39 No.-

동작의 일치하는 정도를 분석하기 위해 적용된 동작은 정상보행동작이었고, 이 때 부하는 체중에 대해 0%BW, 20%BW, 40%BW의 부하를 달리하여 정상보행의 양상과 운동학적 변인간의 인지계수(Recoginition coefficient; Mallwain J.S. 등, 1985)를 구하기 위해 실험 및 분석한 결과 다음과 같은 결론을 얻었다. 부하의 종류가 0%BW, 20%BW일 때 정상보행동안 다른 운동학적 변인간의 인지능력에는 큰 차이를 보이지 않지만 부하가 40%BW이상 및 특수상황과 과부하 보행시에는 인지능력이 감소하여 일치도가 떨어졌다. 동일한 운동학적 변인에서 부하를 달리했을 때 히프각과 무릎각은 부하조건에 상관없이 높은 부하일수록 높은 인지능력을 보였고, 동작의 일치도가 높았다. 히프각속도와 무릎각속도는 부하를 하였을 때 일치감소하였고, 부하조건 간에는 일치도가 매우 높고, 인지능력은 증가했다. 신체중심변위의 경우 부하 및 무부하간의 일치하는 정도는 다소 높은 것으로 나타났고, 부하의 종류에 따라 큰 영향을 받지 않았지만, 신체중심속도는 부하의 종류에 따라 일치도는 감소하여 동작의 인지능력은 적었다. The study was undertaken to investigate congruity of kinematic variables on a kind of load level(%BW) during normal gait with packback system, and the congruity degree was represented with recognition coefficient. The difference of recognition ability between 0%BW and 20%BW was little, but was not in 40%BW, over load situation and grately dropped congruity among other kinematic during variable normal gait. The congruity of hip & knee angle was shown high regardless of loaded conditions in the same kinematic variables, was reduced in hip & knee angular velocity loaded and was shown high between loaded conditions, recognition ability was increased. The congruity degree of COG displacement was rather high in all load level, and was not influenced by load levels, but was decresed according to load levels in COG velocity.

군산시 지하수의 특성에 대한 연구

장재철,성금수,김동원 군산대학교 기초과학연구소 2000 基礎科學硏究 Vol.15 No.-

The purpose of this study is to investigate the pollution characteristics of groundwaters in Kansan city. Volatile organic compounds such as TCE(tri-choroethylene), PCE(tetruchloroethylene), 1,1,1-trichloroethane, THM(trihalo-methane), dichloromethane, pesticides such as diazinon, parathion, malathion, toxic inoganic matters such as As, Hg, Se, Cd, Al, Cr6+, oder, taste and phenol were not detected in the groundwaters. Mean values of groundwater pollution indicators were bellow drinking-water standards, but Bacteria, Total Coliforms, Pb, Mn, NO3-N and NH3-N, total solid and pH exceeded a little in some samples.