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삼백초(三白草)와 어성초(魚腥草)의 암세포(癌細胞)에 대한 독성억제(毒性抑制) 효과(效果)
한상엽,이정호,백승화,이택준,송용선,이기남,Han Sang-Youp,Lee Jeong-Ho,Baek Seung-Hwa,Lee Taek-Jun,Song Yong-Sun,Lee Ki-Nam 대한예방한의학회 2003 대한예방한의학회지 Vol.7 No.2
This study was performed to determine the cytotoxic effect of methanol extract from medicinal plants. 1. The cell viability was determined by MTT method. Their cytotoxic activities against three cancer cell lines such as A549, MDA-MB-231 and SNU-C4 cell line were tested. 2. Among them, The methanol extract of Saururus Ohinensis Bail showed the strongest cytotoxic effect against SNU-C4 cells. These results suggest that the methanol extract of Saururus Ohinensis Bail possessed a potential antitumorous agent. 3. The free radical scavenging activity using DPPH method was the strongest of Saururus Chinensis Bail extract.
인공수정체 공막고정술 후 발생한 푸르처 유사 망막병증 1예
한상엽,강재훈,최영락,천희종,윤희성,Sang Youp Han,Jae Hoon Kang,Yeung Rak Choi,Hui Jong Chun,Hee Sung Yoon 대한안과학회 2006 대한안과학회지 Vol.47 No.9
Purpose: We report a case of Purtscher-like retinopathy following the removal of a dislocated IOL and scleral fixation of a new IOL. Methods: A 60-year-old man presented with sudden visual loss of the right eye. An ophthalmologic examination revealed IOL dislocation. He underwent removal of the dislocated IOL and scleral fixation of the new IOL. Visual acuity was 0.02 in the right eye on the second postoperative day. A fundus examination and fluorescein angiography were performed. Results: A peripapillary multiple cotton wool spot, pale macula and cherry red spot were noted in the right eye. Fluorescein angiography showed arteriolar obstruction around the macula and leakage of the mild arteriolar fluorescein dye. At one month follow-up, macular edema, hemorrhage and peripapillary cotton wool spots were increased. Conclusions: This case of Purtscher-like retinopathy following scleral fixation of the IOL did not have any obvious etiologic cause.
고도근시와 난시 치료를 위해 시행한 ICL 및 반대안 토릭 ICL 삽입술의 임상결과
한상엽,문상정,김호숭,이태헌,이경헌.Sang Youp Han. MD. Sang Jung Moon. MD. Ho Soong Kim. MD. Tae Hun Lee. MD. Kyung Hun Lee. MD 대한안과학회 2010 대한안과학회지 Vol.51 No.6
Purpose: We compared intra-individual visual outcomes and patient satisfaction after implantable contact lens (ICL) and Toric ICL implantation. Methods: Twenty-eight eyes of 14 patients were enrolled in this retrospective study. One eye of each patient was assigned to ICL (ICL Group), and the contralateral eye was allocated to Toric ICL (Toric ICL Group). All patients were examined for visual acuity, refraction, intraocular pressure, slit lamp measurements, and satisfaction one week, one month, two months, and six months postoperatively. Results: Mean spherical equivalents of the two groups were corrected from -7.83D (ICL Group) and -5.55D (Toric ICL Group) to 0.13D and 0.20D, respectively, and the mean refractive cylinders were corrected from 0.92D and 2.60D to 0.42D and 0.27D, respectively, at six months postoperatively. The myopias of these two groups and the astigmatism of the Toric ICL group were effectively corrected. The uncorrected visual acuity (UCVA) of the two groups were 1.02 and 1.05, respectively, at six months postoperatively. The safety index, efficacy index, predictability, and stability were favorable. There were no significant differences between the two groups in terms of postoperative UCVA, intraocular pressure(IOP), vaulting, noticeable complications, or patient satisfaction. Conclusions: The results show ICL implantation is effective treatment for high myopia, and Toric ICL implantation is a viable surgical option for the treatment of compound myopia astigmatism. Selection of proper phakic intraocular lens(IOL) is recommended for correcting astigmatism. J Korean Ophthalmol Soc 2010;51(6):802-808
난시교정인공수정체 삽입 후 난시교정 평가를 위한 KR-1W 수차계의 유용성
김상원,한상엽,이경헌,Sang Won Kim,Sang Youp Han,Kyung Hun Lee 대한안과학회 2012 대한안과학회지 Vol.53 No.11
Purpose: To evaluate the efficacy of the KR-1W aberrometer in assessing the astigmatism and the achieved axis after AcrySof Toric intraocular lens (IOL) implantation. Methods: Thirty-nine patients (48 eyes) that had undergone phacoemulsification and AcrySof Toric IOL implantation were included in the present study. At postoperative 1 month, ocular aberrations of all the eyes were measured using the KR-1W aberrometer before mydriasis and the achieved axis of AcrySof Toric IOL was measured by slit lamp examination after mydriasis. The achieved axis measured by slit lamp examination and the astigmatism of the implanted AcrySof Toric IOL were compared with the KR-1W. Results: The mean achieved lens axis after mydriasis measured by slit lamp examination and KR-1W was 86.43 ± 47.49 degrees and 88.93 ± 41.22 degrees, respectively. The correlation coefficient of the 2 methods was 0.992 (p < 0.001). The measured astigmatism according to the AcrySof Toric IOL model was 1.11 ± 0.47D in SN60T3, 1.71 ± 0.51D in SN60T4, and 3.32 ± 0.78D in SN60T5. Conclusions: Without the need to directly evaluate the axis of implanted Toric IOL after mydriasis, the achieved lens axis can be measured by the KR-1W without mydriasis. The AcrySof Toric IOL model could be assessed by the KR-1W without information about the AcrySof Toric IOL model.
최은수,한상엽,박동원,노주헌,Eun-Su Choi,Sang-Youp Han,Dong-Won Park,Ju-Hun Rho 대한안과학회 2005 대한안과학회지 Vol.46 No.12
Purpose: The subconjunctival sparganosis is rare tissue helminthiasis which developed frequently in abdominal, urethral, ureteral and vertebral cases. Authors report a case of sparganosis in the subconjunctival mass. Methods: A 51-year-old man with reddish non painful mass in his left eye on the subconjunctiva that was unresponsive to medications for 6months was evaluated and treated surgically. On surgical exploration, a white thread-like plerocercoid 0.2×4.7 cm in size was extracted from the subconjunctival mass and actively motile in the bottle filled with saline. It was confirmed as a typical sparganum under histologic examination. Three months after surgery, the lesion disappeared completely. Results: Although rare, parasitic disease should be suspected in a palpable subconjuntival mass unresponsive to the medical treatment.
펨토초레이저를 이용한 백내장 수술과 고식적 백내장 수술 비교
이우석,한상엽,이경헌,Woo Seok Lee,Sang Youp Han,Kyung Hun Lee 대한안과학회 2013 대한안과학회지 Vol.54 No.8
Purpose: To evaluate the surgical results and efficacy of laser refractive cataract surgery with a femtosecond laser compared with conventional phacoemulsification. Methods: Thirty-one eyes from 31 patients underwent laser refractive cataract surgery (femtosecond laser group), and conventional cataract surgery with phacoemulsification was performed in 30 eyes from 30 patients (conventional group). Best corrected visual acuity, spherical equivalent, surgical induced astigmatism, corneal and ocular astigmatism, total high order aberration, Strehl ratio, objective scatter index, diameter of continuous curvilinear capsulorrhexis (CCC), distance from visual axis to the center of CCC, intraocular lens (IOL) tilt, mean absolute error, effective phaco time, average phaco power and operation time were measured to compare the 2 groups. Results: No significant differences were found between best corrected visual acuity, spherical equivalent, surgical induced astigmatism, corneal and ocular astigmatism, total high order aberration, Strehl ratio, objective scatter index, mean absolute error, effective phaco time, average phaco power or operation time. Significant differences were found in the diameter of CCC, distance from visual axis to the center of CCC, and IOL tilt. Conclusions: Results of laser refractive cataract surgery with a femtosecond laser showed more precise CCC, and more stable IOL position than conventional cataract surgery.
이중엽(Joong-Youp Lee),정태규(Tae-Kyu Jung),한상엽(Sang-Yeop Han),김영목(Young-Mog Kim) 한국항공우주연구원 2006 항공우주기술 Vol.5 No.2
본 논문에서는 제어밸브에 대한 유공압적, 기계적, 전기적 부분에 대하여 전반적인 기술 적인 사항 및 설계 기술들을 다루었다. 특히 제어밸브를 이용한 시험으로부터 도출하기 어려운 많은 요소의 동특성을 시스템 모사코드인 AMESim 을 이용하여 예측해보았고, 일반 적인 물리적 동특성도 또한 실제 시험결과와 비교 검토하였다. 또한 제어밸브의 단품 상태에서의 동특성 외에 시스템 연계 상황에서의 특성도 예측하고자 하였고, 이를 근간으로 하 여 발사체 엔진 추진제공급시스템의 제어 관련 분야에 응용하였다. This paper deals with technological and design skills for all pneumatical, hydraulical, mechanical, and electrical parts related to control valve. Especially, a variety of dynamic characteristics, which are not easily extracted from field tests using control valves, are studied by system-simulation code, AMESim. The simulated results are also compared and examined with actual testing results in terms of physical dynamic characteristics. In addition, this paper contains the simulated system characteristics including dynamic characteristics in component level of valve itself. Based on the results, it is applied to control system of propellant feeding system in liquid-propellant engine of satellite launcher.
발사체 추력제어 안정성을 위한 PWM 솔밸브의 탱크압력제어
이중엽(Joong-Youp Lee),홍문근(Moon-Geun Hong),한상엽(Sang-Yeop Han),김영목(Young-Mog Kim) 한국유체기계학회 2006 유체기계 연구개발 발표회 논문집 Vol.- No.-
This paper achieved dynamic characteristics with test to use solenoid valve for flight model that have present. Designed pressure control virtual system which PWM solenoid valve to use test result. Examination compared solenoid valve dynamic characteristics in atmosphere and cryogenic fluid and presented technique and valuation method that measured upstream and down stream pressure of solenoid valve, as well as, temperature, excitation voltage etc. These test results could confirm solenoid valve response time and maximum using frequency characteristic at use in atmosphere and cryogenic temperature and this derived design variables pressure control system from those bases.