알코올 의존 환자의 금단 증상에 영향을 미치는 도파민계(DRD2, DAT, COMT) 유전자 다형성

최태영,김호남,한덕현,민경준,이영식,나철,Choi, Tai Young,Kim, Ho-Nam,Han, Doug-Hyun,Min, Kyung-Jun,Lee, Young-Sik,Na, Chul 대한생물정신의학회 2006 생물정신의학 Vol.13 No.3

목 적: 유전적 요인에 다른 금단 증상의 차이를 파악하는 것은 알코올 의존의 유전적 요인을 파악하는데 도움이 될 수 있으며, 유전적 요인에 따라 개인별 금단 증상을 예측할 수 있다. 본 연구의 목적은 유전자군의 다형성에 따른 금단 증상의 심각도 및 증상의 종류를 파악하는 것이며 이에 따른 치료적 접근을 다양하게 하는 것이다. 방 법: 대상군으로는 19세 이상 65세 이하의 남자 입원 환자 108명을 대상으로 하였고, 유전자 분포 비교를 위하여 76명의 대조군을 두었다. 금단 증상의 평가는 마지막 알코올 섭취로부터 48시간이 지난 시점에서 Clinical Institute Withdrawal Assessment for Alcohol(이하 CIWA-Ar) 척도를 사용하여 평가하였다. 도파민 수송체, 도파민 수용체(DRD2), Catechol-O-Methyltransferase(COMT) 유전자형을 분석하였다. 결 과: 나이, 교육 기간, 유전자 형에서 알코올 의존 군과 대조군 사이의 유의한 차이는 없었다. DRD2 Taq I : 동형 유전자형에서 환청 항목의 점수가, 이형 유전자형에서 CIWA-Ar 총점의 점수가 높았다. 환청 항목의 비교 위험도가 1.34이었다. DAT1 : DAT-9 대립유전자를 가지지 않은 유전자형 집단에서 발한, 불안, CIWA-Ar 총점 항목에서 높은 점수를 보였다. COMT : 유전자 빈도를 보면 이형 유전자형이 동형 유전자형에 비해 CIWA-Ar 총점의 점수가 높았다. 결 론: DRD2, DAT1, COMT 유전자 다형성은 다양한 알코올 금단 증상과 관련이 있으며, 이는 각 유전자와 관련된 신경전달 물질과 연관되어 작용하는 것으로 생각된다. 또한 금단 증상의 심각도와도 밀접한 관련이 있는 것으로 생각되어 알코올 금단 증상을 보이는 환자의 치료에 중요한 역할을 할 것으로 생각된다. Objectives : We investigated the relationship of the alcohol withdrawal symptoms with genetic polymorphism among alcohol dependence patients. Method : The measuring instruments used in this study were the Clinical Institute Withdrawal Assessment for Alcohol(CIWA-Ar). We analyzed DRD2 TaqI A polymorphism, dopamine transporter(DAT 1) polymorphism, and catechol-O-methyltransferase(COMT) polymorphism in 108 male alcoholics and 76 healthy controls. Results : The major findings was as follows. No significant differences for genotype distribution or allele frequency were revealed comparing controls and alcoholic patients. DRD2 Taq I : The subscale score of auditory hallucination among CIWA-Ar scale in homozygote was significantly higher than in heterozygote(OR=1.34). The total score of CIWA-Ar scale in heterozygote was significantly higher than in homozygote. DAT1 : In the subject without DAT-9 gene allele, it was significantly higher of the subscale score of sweating, anxiety among CIWA-Ar scale than in the subject with DAT-9 gene allele. And The total score of CIWA-Ar scale in the subject without DAT-9 gene allele was significantly higher than in the subject with DAT-9 gene allele. COMT : The total score of CIWA-Ar scale in heterozygote was significantly higher than in homozygote. Conclusion : Our results suggest the relationship between specific genetic factors and the withdrawal symptoms of alcohol dependent patients. As the candidate gene of the severity of alcohol withdrawal syndrome, DRD2 Taq1 gene was recommended.

무인항공 영상을 활용한 도심녹지 표면온도 특성 분석 - 익산 소라산 자연마당을 대상으로 -

최태영,문호경,차재규,CHOI, Tae-Young,MOON, Ho-Gyeong,CHA, Jae-Gyu 한국지리정보학회 2017 한국지리정보학회지 Vol.20 No.3

본 연구는 도심온도 저감을 위한 녹지의 기능을 규명하기 위하여 여름철 고온 시간대에 도심녹지에서 나타나는 표면온도 특성을 분석하였다. 도시 내 고립된 녹지인 익산 소라산 자연마당을 대상으로 고해상도 UAV 영상을 활용하여 정밀한 표면온도 자료를 취득하였고, 피복유형, 식생유형, 수종유형, 수종별 녹지용적과 표면온도와의 관계를 분석하였다. 연구결과 피복유형 중 습지와 산림은 저온역, 포장지는 표면온도가 월등히 높은 고온역으로 확인되었다. 식생유형에서는 산림 내 침엽수보다 활엽수의 표면온도가 낮았고, 조경수식재지 내에선 활엽수보다 침엽수의 표면온도가 낮은 반대의 결과가 확인되었다. 장초지보다 단초지의 표면온도가 높아 초지의 용적에 따른 온도차이가 확인되었다. 산림수종유형별 표면온도는 침엽수인 소나무림보다 활엽수인 아까시나무림과 활엽수혼효림의 표면온도가 낮았고, 활엽수혼효림과 아까시나무림간의 미세한 표면온도 차이가 확인되었다. 산림수종유형별 녹지용적과 표면온도 분석결과 소나무림과 활엽수혼효림에서는 기존 연구 결과와 유사하게 녹지용적 증가에 따라 표면온도가 감소하는 음의상관관계가 확인되었다. 그러나 아까시나무림은 용적의 증가에 따라 미세하게 표면온도가 상승하는 약한 양의상관관계가 확인되어 수종에 따라서는 용적과 온도의 일관된 상관성에 예외가 있을 수 있음을 확인하였다. 향후 침엽수와 활엽수간 차이, 용적과 온도의 관계, 수종별 차이 등 녹지의 세부적 속성과 온도의 관계에 관하여 정밀한 공간자료를 활용한 다각적인 연구가 계속되어야 할 것으로 판단된다. This study analyzed the surface temperature characteristics of urban green spaces under high summer temperatures to clarify the functions of green spaces in reducing urban temperatures. We obtained accurate surface temperature data using highresolution unmanned aerial vehicle images of the survey site, which was an isolated green space in the city. We analyzed differences in the surface temperature by land cover type, vegetation type, species type, and the relationship between surface temperature and vegetation volume. Based on the results, among the land cover types, wetlands and forests had low temperatures and paving areas had very high temperatures. Regarding vegetation type, broad-leaved trees had lower temperatures than coniferous trees in forests. However, in planted areas, coniferous trees had lower temperatures than broad-leaved trees. The temperature of long grass was higher than that of short grass, which suggested that the volume of grass affected the temperature. Regarding forest species type, the temperature of broad-leaved Robinia pseudoacacia forest and mixed broad-leaved forest was lower than coniferous Pinus densiflora forest. There was a slight difference in temperature between R. pseudoacacia forest and mixed broad-leaved forest. The analysis of the relationship between vegetation volume and temperature by forest species type indicated a negative correlation, where the temperature decreased with increasing vegetation volume, similar to the results of previous studies. However, we found a weak positive correlation in R. pseudoacacia forest; therefore, an increase in volume may not reduce the surface temperature depending on the dominant species.

설악산 국립공원의 산양 보호구역 설정기법에 관한 연구: 서식지 적합성 모형, 서식지 수용능력, 최소 존속 개체군 이론을 이용하여

최태영,박종화,Choi, Tae-Young,Park, Chong-Hwa 한국조경학회 2005 韓國造景學會誌 Vol.32 No.6

Korean goral (Nemorhaedus caudatus raddeanus) is an endangered species in Korea, and the rugged terrain of the Sorksan National Park $(373km^2)$ is a critical habitat for the species. Since the goral population is threatened by habitat fragmentation, it is essential to establish a reserve for the isolated goral population. The objective of this study was to propose a reserve for Korean goral in the national Park We employed habitat suitability model, habitat capability model, and the concept of minimum viable population. The results of the study were as follows. First, the carrying capacity and optimal density of gorals in the national park were projected to be 449 gorals, and 251 gorals, respectively Second, since only one patch was projected to satisfy the criteria of minimum viable population (50 individuals/during 50 years), the long term extinction possibility of gorals in the site would be very high. Finally, the patch that satisfy the minimum viable population of goral was proposed as the core zone of the goral reserve and adjacent patches were included as buffer zones.

토지이용 유형에 따른 포유류 로드킬 발생 특성

최태영,박종화,Choi, Tae-Young,Park, Chong-Hwa 한국조경학회 2006 韓國造景學會誌 Vol.34 No.5

Wildlife roadkill is a serious problem for road planners and biologists concerned with traffic safety, species conservation, and animal welfare. The objective of this paper was to analyze the effect of land use on the frequency of mammal roadkills. This study took part in three steps. First, data for 1,279 road kills of nine species were collected by survey over 26 months on 107km of roads near the Mt. Jirisan area. Second, the type of land use near the roadkill points was analyzed, and the area of each land use within loom of the road was calculated using GIS. Finally, the question of whether the land use affects the Sequency of mammal roadkills was analyzed by determining the density of roadkill occurrences for each land-use type. The results of the study were as follows. First, the roadkill density of all species was highest near grasslands, especially natural grasslands. Second, when comparing forests and rice fields, roadkill densities of the Eurasian red squirrel, Siberian chipmunk and Korean hare were higher near the forests, while the densities of the raccoon dog, water deer and leopard cat were higher near rice fields. The results of this study could be an essential information source for mitigating the roadkill problem in Korea.

설악산국립공원내 산양(Nemorhaedus Caudatus Raddeanus)의 잠재 서식지 적합성 모형; 다기준평가기법(MCE)과 퍼지집합(Fuzzy Set)의 도입을 통하여

최태영,박종화,Choi Tae-Young,Park Chong-Hwa 한국조경학회 2004 韓國造景學會誌 Vol.32 No.4

Korean goral (Nemorhaedus caudatus raddeanus) is one of the endangered species in Korea, and the rugged terrain of the Soraksan National Park (373㎢) is a critical habitat for the species. But the goral population is threatened by habitat fragmentation caused by roads and hiking trails. The objective of this study was to develop a potential habitat suitability model for Korean goral in the park, and the model was based on the concepts of fuzzy set theory and multi-criteria evaluation. The process of the suitability modeling could be divided into three steps. First, data for the modeling was collected by using field work and a literature survey. Collected data included 204 points of GPS data obtained through a goral trace survey and through the number of daily visitors to each hiking trail during the peak season of the park. Second, fuzzy set theory was employed for building a GIS data base related to environmental factors affecting the suitability of the goral habitat. Finally, a multiple-criteria evaluation was performed as the final step towards a goral habitat suitability model. The results of the study were as follows. First, characteristics of suitable habitats were the proximity to rock cliffs, scattered pine (Pinus densiflora) patches, ridges, the elevation of 700∼800m, and the aspect of south and southeast. Second, the habitat suitability model had a high classification accuracy of 93.9% for the analysis site, and 95.7% for the validation site at a cut off value of 0.5. Finally, 11.7% of habitatwith more than 0.5 of habitat suitability index was affected by roads and hiking trails in the park.

초음파를 이용한 실측 두께 측정과 재질 렌더링

최태영(Taeyoung Choi),진성아(Seongah Chin) 대한전자공학회 2014 전자공학회논문지 Vol.51 No.6

대학원 교육과정 개선 방안

최태영(Tae Young Choi) 영남신학대학교 2008 신학과 목회 Vol.29 No.-

영남신학대학교의 특성화 방향과 미래 인재상에 기초한 교육방향과 목적 및 교과과정에 대한 연구

최태영(Choi, Tae-Young) 영남신학대학교 2014 신학과 목회 Vol.42 No.-

Nowadays, the Youngnam Theological University and Seminary encounters great crises along with most other universities in our country. These are the crises: the people who are expected to enter universities are going to decrease rapidly in about 10 years; the total membership of Korean churches, -especially Sunday school students-, are diminishing quickly. In addition, the finance of churches are becoming a problem; and the image of Christianity toward society is growing worse as well. These causes are making the department of theology in our university weak. To overcome these crises and to gain competitive advantages, we should educate virtuous people through right specialized qualities. After all, for this purpose, it is almost a necessity to make a revolutionary change in curriculum. Our university’s department of theology should seek to provide students with a sound foundation for the next course, -the master of divinity degree. The curriculum the department of theology offers is a kind of preliminary course for the M. Div. course, where one should be well educated in academic and ministerial theology. Therefore, the department of theology needs to provide the following: first, to soundly equip syudents with a humanistic foundation, second, to master Biblical languages and Scriptures, third, to be skillful in speaking and writing both English and Chinese, and in working with computers and the internet etc. and lastly, to have pious leadership. With these perspectives, I propose a new curriculum for the department of theology of YoungNam Theological University and Seminary.

GaN Transistor를 이용한 10W 광대역 UHF 증폭기 모듈 설계

최태영(Taeyoung Choi),마백일(Bakil Mah),서성원(Sungwon Seo),이상필(Sangpil Lee),이경원(Kyungwon Lee) 한국통신학회 2010 한국통신학회 학술대회논문집 Vol.2010 No.6

Agency Theory and Dividend Policy of American Life Insurance Companies

Choi, Tae-Yeong(최태영) 대한경영학회 1999 大韓經營學會誌 Vol.21 No.-