Potential role of immunological factors in early diagnosis of cancer cachexia in C26 tumor‑bearing mice

주재은,김미숙,강주현,이지영,이미소,김은호,정남현,정윤경 한국응용생명화학회 2019 Applied Biological Chemistry (Appl Biol Chem) Vol.62 No.-

Cachexia is a wasting syndrome associated with high mortality in cancer patients through inducing the failure of normal metabolism and reducing the efficacy of cancer treatment. Thus, it is critically important to diagnose cancer cachexia early. To provide background data for the diagnosis of cachexia, cancer cachectic factors were characterized in the present situation, including immunological cachectic changes during cachexia progression in a cancer cachexia mouse model. Major constitution of cachexia progression is known as the stages of pre-cachexia, cachexia, and refractory cachexia. In the pre-cachexia stage, the weights of immune-related organs, including the thymus and spleen were significantly. T cell populations in spleen were markedly reduced and cachectic cytokines consistently increased in a time-dependent manner. Immunosuppression by activation of cytotoxic T-lymphocyte-associated antigen 4 was induced earlier in CD4+ cells versus other T cell populations. Furthermore, monocyte chemoattractant protein 1 and interleukin-6 levels in the cachexia group were significantly increased at 3 days from C26 cell inoculation whereas significant carcass weight loss as a classical diagnostic marker occurred at 9 days from C26 cell inoculation. In conclusion, the initiation of cachectic immunological changes was observed prior to weight loss, during the pre-cachexia stage. Accordingly, these findings reveal that the monitoring of humoral and immunological factors may be more sensitive than weight loss for the initial diagnosis and treatment of cachexia.

주식 배합에 관한 연구 Ⅰ

주재은,김혜영,박근희,안혜원,최숙기 연세대학교 생활과학대학 1971 婦學 Vol.4 No.-

Anti-Diabetic Effects of Red Rose Flowers in Streptozotocin-Induced Diabetic Mice

주재은,주용훈,정남현,한성희,이용권 한국응용생명화학회 2014 Applied Biological Chemistry (Appl Biol Chem) Vol.57 No.4

Diabetes mellitus is a common chronic metabolicdisease that is of increasing concern, because it frequently leads tocomplications such as cardiovascular diseases and cancer. Plantshave been studied as a potential source for anti-diabetics tosupplement dietary modifications, insulin, and other medications. The components of green tea polyphenols can be changed byprocesses such as browning. This processing method was appliedto the red rose flower to determine whether the processed or nonprocessedrose flower has an anti-diabetic effect on the streptozotocininduceddiabetic mouse. Aqueous extracts of processed and nonprocessedrose flowers were analyzed using liquid chromatography/mass spectrometry. The results show that the polyphenol contentdecreased with browning. The hemoglobin A1c level, an indicatorof long-term diabetes, in diabetic mice after administration ofextracts of browned rose flowers for 24 and 48 h were lower thanthose after administration of extracts of non-browned roseflowers. Moreover, the activity of aspartate transaminase, which isoften high in diabetic patients, was low in all groups treated withrose flowers, whether they were non-browned or browned. Takentogether, these results indicate that extracts from red rose flowershave long-term anti-diabetic effects, and that this effect isindependent of the level of polyphenols in the extract.

일부 대학생의 천연 세치제 사용 후 호감도와 만족도 조사

주재은,이민경 한국구강보건과학회 2019 한국구강보건과학회지 Vol.7 No.3

Objectives: Toothpaste, which is essential for toothbrushing, suppresses the formation of calculus to clean the oral cavity, prevent tooth decay and periodontitis, avoid dental plaque, and remove halitosis. However, numerous recent reports on the side effects and toxicity of the chemical compounds in toothpaste have led to active research aiming to develop oral hygiene products that contain safe substances, thereby increasing the development of and interest in natural materials. According to many studies, natural toothpaste has been made from Artemisia capillaris Thunberg, which has strong antibacterial effects throughout the human body; cinnamon, which is used as food and medicine, has a strong scent that helps control halitosis and suppress fungal growth. This study aims to evaluate the favorability of and satisfaction with the use of toothpaste that contains natural materials extracted from A. capillaris Thunberg and cinnamon. Methods: In the experiment, college students used natural toothpaste for five days, and their oral hygiene before and after use was assessed. For statistical analysis, a frequency analysis and a confidence interval test were run using the software SPSS WIN 25.0. Results: Most of the subjects used the rotation method, and 72.5% of them had no experience using natural toothpaste. The expected effect of the natural toothpaste was higher in halitosis reduction than in bacterial reduction. The use of the natural toothpaste also showed a reduction in oral resident bacteria. Conclusions: The favorability of and satisfaction with the use of natural toothpastes were determined. The natural toothpaste effectively removed oral resident bacteria.

중년여성의 신체지각과 이상적 연령에 따른 기성복 맞음새 만족도

주재은,정찬진,정명선 복식문화학회 2001 服飾文化硏究 Vol.9 No.5

The purposes of this study were 1) to examine the effects of the difference between actual and perceived body type and body cathexis on satisfaction with fit and 2) to identify the effect of the difference between chronological and ideal age of middle-aged woman on satisfaction with fit of ready-to-wear. For this study, questionnaires were administered to 500 middle-aged woman in Kwangju. Employing 402 respondents, data were analyzed by using χ2-test, t-test and Pearson Correlation. The results were as follows; 1) There were significant differences between actual and perceived body types among middle-aged women. Those who were inconsistent with actual and perceived body types had a tendency to perceive themselves to be obeser than actual body, 2) Those who were inconsistent with actual and perceived body types had a lower satisfaction level with apparel fit sites at jacket length, hip width, crotch length and waist width than those who were consistent with actual and perceived body types. 3) Correlation for body cathexis and satisfaction with fit of ready-to-wear was significantly positive. 4) There were significant differences between chronological and ideal ages. 5) Those who were inconsistent with chronological and ideal ages had a lower satisfaction level with apparel fit sites at neckline, shoulder width, bust, sleeve length, sleeve width, jacket length, waist width, hip width and skirt length than those who were consistent with chronological and ideal ages. Key words: perceived body type(신체지각), Ideal age(이상적 연령), satisfaction with fit(기성복 맞음새 만족도).

여대생의 내향적-외향적 특질과 신체 만족도에 따른 의복 이미지 선호도

주재은, 정명선 전남대학교 가정과학연구소 2000 生活科學硏究 Vol.10 No.-

The purpose of this study was to investigate the effects of internal-external personal traits and body cathexis of college women on their clothing image preferences. Data were collected using questionnaire from 400 female students from 4 Universities located in Kwangju. Data from 332 respondents were analyzed using SAS package. The frequency, percentage, arithmetic mean, t-test, correlation. Principal Factor Analysis were used. The results were as follows : 1.The body cathexis of respondents to their own body was not so high, the satisfaction to their body parts were face features, shoulder, arms and hands, legs and feet, height, torso, physique, weight orderly. 2.The clothing image preferences classified by the 5 factors : usual-individualis tic, casual-formal, refined-splendid, and masculine-feminine image. 3.The extroversion group preferred the individualistic clothing image more to introversion group and the introversion group preferred the masculine clothing image more to extroversion group. 4.Higher the body cathexis respondents preferrer the splendid and the individualistic clothing images. 5.Higher the satisfaction to face features, shoulder, arms, and hands, legs and feet the respondents preferrer the splendid clothing image. 6.Higher the body cathexis, the respondents belong to introversion group preferrer the splendid clothing image, and the respondents belong to extroversion group preferrer the casual clothing image.

중년여성의 신체지각과 이상적 연령에 따른 기성복 맞음새 만족도

주재은,정찬진,정명선 복식문화학회 2001 服飾文化硏究 Vol.9 No.5

여대생의 내향적-외향적 특질과 신체 만족도에 따른 의복 이미지 선호도

주재은(Jae Eun Ju),정명선(Myung Sun Chung) 전남대학교 생활과학연구소 2000 生活科學硏究 Vol.10 No.-

The purpose of this study was to investigate the effects of internal-external personal traits and body cathexis of college women on their clothing image preferences. Data were collected using questionnaire from 400 female students from 4 Universities located in Kwangju. Data from 332 respondents were analyzed using SAS package. The frequency, percentage, arithmetic mean, t-test, correlation. Principal Factor Analysis were used. The results were as follows: 1. The body cathexis of respondents to their own body was not so high, the satisfaction to their body parts were face features, shoulder, arms and hands, legs and feet, height, torso, physique, weight orderly. 2. The clothing image preferences classified by the 5 factors : usual-individualis tic, casual-formal, refined-splendid, and masculine-feminine image. 3. The extroversion group preferred the individualistic clothing image more to introversion group and the introversion group preferred the masculine clothing image more to extroversion group. 4. Higher the body cathexis respondents preferrer the splendid and the individualistic clothing images. 5. Higher the satisfaction to face features, shoulder, arms, and hands, legs and feet the respondents preferrer the splendid clothing image. 6. Higher the body cathexis, the respondents belong to introversion group preferrer the splendid clothing image, and the respondents belong to extroversion group preferrer the casual clothing image.

Investigating the Structural Relationships among Sense of Presences and Institutional Support Toward Online Learner Satisfaction in a Cyber University

주영주,주재은,김은경 이화여자대학교 교과교육연구소 2016 교과교육학연구 Vol.20 No.6

This study analyzes the online survey results of 788 students at W Cyber University to investigate the structural relationships among learners' sense of presence of the Community of Inquiry framework (Teaching, Cognitive, and Social Presence) and institutional support toward learner satisfaction by applying structural equation modeling. After satisfying the fitness of the measurement and the structural models, this study confirmed the direct effect of Teaching Presence, Cognitive Presence, and institutional support on learner satisfaction. Social Presence, however, did not show a significant causal relationship toward satisfaction, probably due to the lower level of learners' perception and needs for Social Presence in this study. These results suggest that online education should establish strong Teaching Presence with clear learning objectives and immediate feedback, and Cognitive Presence emphasizing on interactive, reflective learning activities to generate new knowledge. It was also confirmed that institutional support such as quality administrative assistance and institutional culture had a direct effect on learner satisfaction in a cyber university. In order to understand and improve learners' experiences in an online learning environment, research on the multiple components of the Community of Inquiry's presences, and how these components interact with other learning conditions (e.g. learners' characteristics) is suggested.

워크숍 : 지오지브라를 활용한 미적분 교육과 3차원 기하

김동석,최경식,주재은 한국수학교육학회 2014 뉴스레터 Vol.30 No.5

지오 지브라는 ‘모두를 위한 움직이는 수학-과학’ 이라는 모토로 수학교육 및 STE따d교육을 위한 기능을 제 공하는 무료 수학-과학 소프트웨어이다. 지오 지브라는 초등학교부터 대학교에 이르는 범위의 모든 수학 개념을 소프트왜어내에 구현하였으며, 특별히 미적분과 3차원 기하에 대하여 강력한 기능을 갖고 있다. 본 워크삽에서는 지오 지브라를 활용하여 고등학교 및 대학교 교양미적분과 3차원 기하에 활용할 수 있는 다양한 방안에 대하여 살펴보고자 한다.