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조현석,김갑성,Cho, Hyun-seok,Kim, Kap-sung The Korean AcupunctureMoxibustion Medicine Society 2003 대한침구의학회지 Vol.20 No.1
목적 : 면역억제 작용을 지닌 것으로 알려진 전갈약침(BMK)의 IL-1으로 야기된 1차성 골관절염 인체 연골 세포에 대한 항염증 효과 골 기능 효과에 대해 연구하였다. 방법 : 골관절염 연골에서 채취된 인체 연골세포는 ID-1(2ng/ml)에 의해 처리되어졌으며, IL-1과 BMK($10{\mu}g/ml$)를 함께 처리한 연골세포와 비교하였다. 결과 : IL-1 단독처리된 연골세포에 비해 BMK가 함께 처리된 연골세포에서 연골세포의 손실과 퇴화의 중요한 요소인 NO의 생산량이 의미있게 저하되었다. IL-1단독으로 처리된 연골세포보다 IL-1과 BMK가 함께 처리된 연골세포에서 iNOS mRNA의 단백질 합성이 의미있게 감소하였다. 또한, 전사인자로서의 NF-B의 활성화가 IL-1 단독으로 처리된 연골세포에 비하여 BMK가 함께 처리된 군에서 상대적으로 의미있게 억제되었다. 결론: 이상의 결과를 종합하면 BMK가 인제 골관절염 연골에 있어서 NF-B 활성화에 의존한 IL-1 유도염증의 치료상에 효과적인 반응억제제임을 시사하며, 골 세포의 골 재흡수 활동에 효과적임을 시사한다.
기울어진 비구면 프레넬 렌즈와 C-8 type 전구를 이용한 해상용 랜턴의 배광곡선 시뮬레이션을 통한 성능평가
조현석,조재흥,박승남,박철웅,김용완,김종태,Cho Hyun Seok,Jo Jae Heung,Park Seungl Nam,Park Chul Woung,Kim Yong Wan,Kim Jong Tae 한국광학회 2004 한국광학회지 Vol.15 No.6
대구경이 가능하며 가벼운 프레넬 렌즈로 10 해리 (18.53 km)까지 빛을 비출 수 있는 해상용 랜턴을 설계하고 배광곡선을 시뮬레이션하였다. 렌즈설계 프로그램으로 직경 250 mm와 300 mm인 프레넬 렌즈를 설계하였으며, 이 프레넬 렌즈의 groove 변수들을 최적화하였다. 해상용 랜턴에서 사용하는 전구의 배광곡선을 고려하여 이 프레넬 렌즈의 배광곡선을 조명설계 프로그램으로 계산하였다. 이 결과 전구를 최적의 위치로 정렬하였을 때 이 해상용 랜턴들의 최대광도는 각각 KS 규격인 720 cd를 훨씬 넘는 1000 cd(직경 250 mm의 해상용 랜턴의 경우)와 1300 cd (직경 300 mm의 해상용 랜턴의 경우)로 계산되었다. 그리고 전구의 정렬오차를 정하기 위하여 렌즈의 초점거리에서 벗어난 정도에 따라 배광곡선이 변하는 정도도 알아보았다. Providing marine signal lanterns with advantages of little weight as well as large aperture, a Fresnel lens has been adopted to transfer the beam from the lanterns up to 10 nautical miles (18.53 km). A Fresnel lens with the diameter of 250 mm and 300 mm was designed by a lens design program and optimized by adjusting the groove parameters of the lens. The angular luminous intensity distribution (ALID) of this lens was calculated by using an illumination analysis program considering the ALID of a light bulb. At the best alignment of the bulb, the maximum luminous intensities (MLI) of the lantern were 1000 cd (in the case of 250 mm diameter) and 1300 cd (in the case of 300 mm diameter). These are more than the critical value of 720 cd that is the Korean Standard of MLI for the marine lantern. The ALID was investigated as a function of misalignment from the lens focus to determine the tolerance of the alignment ranges.
조현석,최유행,장준혁,Cho, Hyun-Seok,Choi, Yoo-Haeng,Jang, Jun-Hyouk 대한침구의학회 2000 대한침구의학회지 Vol.17 No.4
In the treatment of hemifacial spasm, the operative methods, such as neurovascular decompression, rhizotomy etc. are the most efficacious therapy on its control. But, due to some side effects and complication, pharmacotherapy has been the first attempted by first intention of hemifacial spasm. The cabamazepine is the most commonly used agent, however it is often inefficacious in some cases, and attenuates as the time passes, engages in some symptoms, such as dizziness, nausea, vomiting, and causes an aplastic anemia, it has many deficiencies in becoming the first intention. Acupuncture is a simple, effective and conservative spasm control modality. It is so simple to use in hemifacial spasm. We had observed 5 cases of hemifacial spasm which were treated by acupuncture in our hospital recently. We reported these cases and reviewed related literatures briefly. The results of treatment are as follows : The average grade of spasm intensity classified by Scott's description was 3 before acu-therapy and it became 2 after the therapy. These results suggest that acupuncture and ear-acupuncture were effective as the first intention in healing hemifacial spasm.
조현석,이현진,김종규,이상남,강용혁,Cho, Hyun-Seok,Lee, Hyun-Jin,Kim, Jong-Kyu,Lee, Sang-Nam,Kang, Yong-Heack 한국태양에너지학회 2012 한국태양에너지학회 논문집 Vol.32 No.suppl3
It is important to produce the high-temperature and high-pressure air for the concentrated solar power system using the combined cycle. In this paper, we designed two types of tubular receivers to heat up the compressed air and provided their preliminary experimental results for performance evaluation and further improvements. The developed receivers are in a square cavity shape surrounded by flow conduits for easy scale-up and radiation loss reduction. The two receivers were tested with 5 bar air in the KIER solar furnace and evaluated in terms of the outlet temperature and the efficiency.
조현석(Cho Hyun-Seok),동재용(Dong Jae-Young),오상준(Oh Sang-Jun),이주한(Lee Ju-han),서태범(Seo Tae-Beom) 한국태양에너지학회 2010 한국태양에너지학회 학술대회논문집 Vol.2010 No.4
This paper describes the procedure and calculation results of basic design and steady state variation of Performance of 200㎾ solar tower power plant. Solar power towers generate electric power from sunlight by focusing concentrated solar radiation on a tower-mounted heat exchanger (receiver). The system uses hundreds to thousands of sun-tracking mirrors called heliostats to reflect the incident sunlight on to the receiver. To simulate process of plant, calculation computed by using commercial software of ASPEN HYSYS. In order to Simulate the plant process, the design value are necessary. Each Design value are offered by DAEGU CITY GAS Corp.
2009 Influenza A H1N1 감염 중 소아 중증 환자에 대한 고용량 Oseltamivir 투여 효과
조현석 ( Hyun Seok Cho ),민세라 ( Se Ra Min ),이준호 ( Joon Ho Lee ),안성연 ( Sung Yeun Ahn ),이현수 ( Hyeon Soo Lee ),양정희 ( Jeong Hee Yang ),김자경 ( Ja Kyoung Kim ) 대한천식알레르기학회 2014 Allergy Asthma & Respiratory Disease Vol.2 No.1
Purpose: We aimed to evaluate the use and safety of double dose oseltamivir for patients manifesting severe respiratory symptoms or showing no improvement of clinical symptoms after 72 hours’ treatment with the usual oseltamivir dosage. Methods: We analyzed the clinical features of 2009 influenza A H1N1 inpatients who had been admitted to a university hospital’s Department of Pediatrics between August 2009 and January 2010. The Influenza A H1N1 diagnoses were confirmed by real-time reverse transcriptase polymerase chain reaction. Results: The study participants numbered 157 (mean age, 5.0 years; male-to-female ratio, 1.1:1). Among them, twenty (mean age, 5.2 years) were administered double dose oseltamivir. This double dose group showed higher peak body temperatures and more abnormal radiologic results than the other, usual-dose group. The mean time duration between high fever and afebrile status after initiation of double-dose oseltamivir administration was 2.1 days, whereas that within the usual-dose group was 1.7 days. There were no adverse effects in the patients treated with double-dose oseltamivir. Conclusion: Double-dose oseltamivir was well tolerated in patients with severe 2009 influenza A H1N1 infection. (Allergy Asthma Respir Dis 2014;2:64-69)
신생아에서 발생한 혈관종을 동반한 선천성 거대 멜라닌세포 모반 1례
조현석 ( Hyun Seok Cho ),추영광 ( Young Kwang Choo ),민세라 ( Se Ra Min ),이상열 ( Sang Yeol Lee ),이승구 ( Seung Gu Lee ),이현수 ( Hyeon Soo Lee ) 대한주산의학회 2012 Perinatology Vol.23 No.2
Giant congenital melanocytic nevi are very rare skin lesions with an estimated prevalence of 1 in 20,000 live births, and have high risk of malignant melanoma development and leptomeningeal melanocytosis. Hence, its early and exact diagnosis in the neonatal period is important and essential. Only seven cases of giant congenital melanocytic nevi have been reported in Korea, of which none of the cases were associated with hemangioma. Herein, the authors describe a case of giant congenital melanocytic nevi with huge hemangioma with the patho logic findings that exhibited benign and provide a literature review.