Uveoretinal Adverse Effects Presented during Systemic Anticancer Chemotherapy: a 10-Year Single Center Experience

조아란,윤영희,김중곤,김윤전,이주용 대한의학회 2018 Journal of Korean medical science Vol.33 No.7

Background: The present study describes our 10-year experience with uveoretinal adverse events that manifest because of chemotherapy. Methods: A retrospective chart review was performed for all patients who presented to the ophthalmologic department while undergoing systemic chemotherapy between July 2005 and June 2015. Results: A total of 55 patients (mean age, 51.2 years, 38 women [69.1%]) suspected of having uveoretinal disease owing to the use of chemotherapeutic agents alone were enrolled. Breast cancer was the predominant disease (36.4%); noninfectious anterior uveitis (21.8%) was the most common condition. Bilateral involvement was observed in 16 patients (29.1%). Although cisplatin (21.8%) was the most commonly used drug, daunorubicin, cytarabine, tamoxifen, toremifene, and imatinib were also frequently used. The median duration until ophthalmologic diagnosis was 208.5 days (range, 19–5,945 days). The proportion of patients with final visual acuity (VA) < 20/40 Snellen VA (0.5 decimal VA) was 32.7%. However, no relationship was observed between final VA < 20/40 and age, sex, therapeutic agents, and metastasis. Conclusion: Uveoretinal complications were mostly mild to moderate and exhibited a favorable response to conservative therapy. A considerable number of patients exhibited significant irreversible loss of vision after cessation of the causative chemotherapeutic agent. Ophthalmological monitoring is required during chemotherapy.

제 2 회 전국 초 , 중 , 고 , 대학생 한자교육 진흥을 위한 글 현상공무 수상작 : 교육인적자원부장관상 ; 한자교육은 즐거워요 !

조아란 전국한자교육추진총연합회 2001 한글한자문화 Vol.28 No.-

정서 영상에 대한 정서표상 및 개인 간 반응 일관성

조아란,김현중,김종완 한국감성과학회 2023 감성과학 Vol.26 No.3

This study examined the affective representation and response consistency among individuals using affective videos, a naturalistic stimulus inducing emotional experiences most similar to those in daily life. In this study, multidimensional scaling was conducted to investigate whether the various affective representations induced through video stimuli are located in the core affect dimensions. A cross-participant classification analysis was also performed to verify whether the video stimuli are well classified. Additionally, the newly developed intersubject correlation analysis was conducted to assess the consistency of affective representations across participant responses. Multidimensional scaling revealed that the video stimuli are represented well in the valence dimension, partially supporting Russell (1980)'s core affect theory. The classification results showed that affective conditions were successfully classified across participant responses. Moreover, the intersubject correlation analysis showed that the consistency of affective representations to video stimuli differed with respect to the condition. This study suggests that the affective representations and consistency of individual responses to affective videos varied across different affective conditions.

건성안 지표와 서로 다른 두 기기로 측정된 전면 각막 고위수차의 관계 분석

조아란,강나희,전루민.Ah Ran Cho. MD. Na Hee Kang. MD. Roo Min Jun. MD. PhD 대한안과학회 2015 대한안과학회지 Vol.56 No.1

Purpose: To compare the corneal first surface higher-order aberrations (HOAs) of normal subjects and patients with dry eye using KR-1W<SUP>Ⓡ (Topcon Corp., Tokyo, Japan) and Pentacam<SUP>Ⓡ HR (Oculus Inc., Dutenhofen, Germany). We analyzed the relationship between the aberrations and the diagnostic parameters of dry eye. Methods: We evaluated anterior corneal HOAs in 71 normal eyes and 71 dry eyes using KR-1W<SUP>Ⓡ and Pentacam<SUP>Ⓡ. Dry eye patients were examined for fluorescein staining, tear break-up time (TBUT), and Schirmer I test. Ocular Surface Disease Index (OSDI) was used for assessment of subjective symptoms in dry eye patients. Results: HOAs measured by both instruments were greater in the dry eye group than in the control group, although HOAs using KR-1W<SUP>Ⓡ only achieved statistical significance. The anterior corneal HOAs measured by the 2 instruments were significantly correlated with superficial punctate keratitis. Moreover, TBUT and the Shirmer I test negatively correlated, and OSDI positively correlated, with anterior corneal HOAs. Conclusions: The HOAs in patients with dry eye were significantly different from controls and tended to increase with disease severity. KR-1W<SUP>Ⓡ might be more useful than Pentacam<SUP>Ⓡ to detect tear film instabilities. J Korean Ophthalmol Soc 2015;56(1):6-12

조선시대 무속복식연구

조아란,조효순 한국복식학회 1997 服飾 Vol.34 No.-

1) The color of JOGORI and CHIMA was such gorgeous and those garments were put on during the events of GAM-EUNG-CHUNG-BAI, HO-GU-GEO-RI, JO-SANG-GEO-RI, DEWT-JUN and CHAN-BOO-GEO-RI. 2) BULSA-JANG-SAM(JE-SUK-GEO-RI) was white colored and had wide sleeves, putting on a pink priestrobe and a pink belt on it. 3) they put on HONG-CHUL-NIK(GU-REUNG) and CHONG-CHUL-NIK(DAE-GEO-RI). 4) They put on GOO-GUN-BOK(JUN-RIP, JUN-BOK(BYUL-SUNG-GEO-RI), DONG-DA-RI(Expel the demon). 5) MONG-DOO-RI(MAN-SIN-MAL-BYUNG)put on the garment con-structed with the color and form of a w-hite, straight collar, a wide sleeve and a pink belt. 6) A long robe was colored with green(GAM-EUNG-CHUNG-BAI), and was used not as a headdress but as a man`s overcoat. 7) CHANG-EUI was a green colored small CHAHG-EUI(SUNG-JO-GEO-RI). As observed above, the Shaman apparel during Chosun Dynasty is a part of the traditional clothing originated from THE THEORY OF THE COSMIC DUAL FORCES and The FIVE ELEMENTS (i.e.metal, wood, water, fire and earth). It`s basic form and wearing method were not so different from the traditional clothing but it`s color and shape were chiefly similar to the official uniform during Chosun Dynasty and the official uniform was the symbol of authority (almost almighty) at that time of period and to that the Shaman apparel was co-nstructed with the more gorgeous colors to emphasize the sanctity or the descent of the Divine Being from Heaven. We realized that a Shaman had put on the symbolic garment suitable for the grade and nature of the Divine Body at every events to enter into The World of Gods.

한국인 정상안압녹내장 환자에서 안구반응분석기의 진단적 유용성

조아란,최윤정,류진영,최규룡 대한안과학회 2015 대한안과학회지 Vol.56 No.1

Purpose: To compare the parameters measured with the ocular response analyzer (ORA; Reichert Inc., Depew, NY, USA) between normal control subjects and patients with normal tension glaucoma (NTG) and to investigate clinical usefulness of ORA. Methods: Intraocular pressure (IOP) and central corneal thickness (CCT) were measured using the Goldmann applanation tonometer (GAT) in 100 eyes of 100 normal subjects and 100 eyes of 100 NTG patients. Four types of ORA parameters, corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated IOP (IOPg), and corneal-compensated IOP (IOPcc) were also measured. Results: The mean CH values were 11.2 mm Hg and 10.3 mm Hg and the mean CRF values were 10.8 mm Hg and 9.9 mm Hg in the normal subjects group and the NTG group, respectively. Mean CH and CRF were significantly lower in NTG patients (p < 0.001) and the IOPcc were higher than normal subjects (p = 0.004). IOPg was in agreement with the GAT IOP (ICC = 0.811) and IOPcc was not correlated with CCT. The cut-off value of ‘IOPcc - IOPg’ as the diagnostic standard parameter was -0.05 mm Hg (sensitivity; 76%, specificity; 55%). Conclusions: IOPg measurements were similar to GAT IOP, and other ORA parameters (CH, CRF, IOPcc) were significantly different between normal subjects and NTG patients. Consequently, the difference of IOPcc and IOPg could be a useful parameter in NTG diagnosis. J Korean Ophthalmol Soc 2015;56(1):86-92

앞허혈시신경병증으로 발견된 모야모야병 1예

조아란,김소영,Aran Cho,MD,So Young Kim,MD,PhD 대한안과학회 2011 대한안과학회지 Vol.52 No.7

Purpose: To present a case of a patient with decreased visual acuity and anterior ischemic optic neuropathy diagnosed with advanced Moyamoya disease. Case summary: A 46-year-old woman presented sudden episodes of headache and decreased visual acuity. On her first visit, her best corrected visual acuity was 20/25 in the right eye and 20/70 in the left eye. The left eye pupil was dilated with a relative afferent papillary defect. Fundus examinations revealed disc swelling in the left eye. After being admitted, steroid pulse therapy was started and Magnetic Resonance Imaging (MRI) studies revealed Moyamoya disease. The diagnosis was confirmed via Magnetic Resonance Angiography (MRA). After steroid pulse therapy, the headaches and visual acuity improved and the patient is continuing follow-up visits at neurosurgery and ophthalmology clinics. Conclusions: Patients with Moyamoya disease may initially present symptoms and signs of anterior ischemic optic neuropathy. J Korean Ophthalmol Soc 2011;52(7):887-892

망막분지정맥폐쇄에 동반된 황반부종의 유리체내 베바시주맙 및 후테논낭하 트리암시놀론 병합요법

조아란,최경식,이미리,이성진 대한안과학회 2012 대한안과학회지 Vol.53 No.2

Purpose: To compare the clinical outcomes of intravitreal bevacizumab with and without posterior subtenon triamcinolone acetonide injections for macular edema with branch retinal vein occlusion. Methods: Intravitreal bevacizumab injection (single group) or intravitreal bevacizumab injection with posterior subtenon triamcinolone acetonide injection (combined group) were performed in 30 eyes each, and intravitreal bevacizumab injection was given once a month in both groups until macular edema was in the normal range. A best corrected visual acuity and central macular thickness were measured pre- and post- injection. Results: The required number of injections to achieve improved macular edema in the normal range was 2.8 ± 0.5 times in the single group and 2.0 ± 0.6 times in the combined group. Six months after injection, average central macular thickness decreased to 185.3 ± 63.5 μm in the single group and to 260.0 ± 74.6 μm in the combined group. The best corrected visual acuity (log MAR) improved from 0.71 ± 0.63 to 0.35 ± 0.44 in the single group and from 0.67 ± 0.42 to 0.08 ± 0.11 in the combined group. The number of cases in which the central macular thickness increased again within 6 months after the injections was 19 eyes in the single group and 6 eyes in the combined group. Conclusions: In macular edema with branch retinal vein occlusion, early rapid recovery of visual acuity and decrease of central macular thickness were observed due to the synergistic effect of bevacizumab and triamcinolone acetonide in combined therapy, and the recurrence frequency of macular edema was reduced by the long-term effect instilled by the long half-life of triamcinolone acetonide. J Korean Ophthalmol Soc 2012;53(2):276-282

Bilateral Branch Occlusive Retinal Vasculitis Induced by Septic Embo-lism in Endogenous Klebsiella Endo-phthalmitis

조아란,김중곤 대한안과학회 2017 Korean Journal of Ophthalmology Vol.31 No.2

LIDAR 센서용 대면적 스캐닝 마이크로 미러의 설계

조아란(Ah Ran Cho),한아름(Aleum Han),주선아(Suna Ju),지창현(Chang-Hyeon Ji) 대한전기학회 2015 대한전기학회 학술대회 논문집 Vol.2015 No.11